virus epstein barr virus nuclear antigen 1 and anti smd antibodies
Báo cáo y học: "Identification of a SmD3 epitope with a single symmetrical dimethylation of an arginine residue as a specific target of a subpopulation of anti-Sm antibodies" ppsx
... erythematosus Autoantibody to U1-68 kD SMP positive Percentage U1-C SmBB' SmD Ro-52 Ro-60 La histone dsDNA β2 Glycoprotein 8 /16 12 /25 11 /26 11 /22 11 /16 5/22 12 /48 4/22 10 /38 13 / 51 4 /16 χ2 test: 48% ... immune recognition Epstein Barr virus, Epstein Barr virus nuclear antigen and anti- SmD antibodies Epitope-mapping studies on SmD1 have identified an epitope motif (amino acids 95 11 9) that crossreacts ... predictor of antigenicity on the Sm complex On U1-RNP-A, SmB' and SmD1 , the average pI of antigenic regions was 10 .4 (nonantigenic 6.0) and on SmD2 and SmD3 the pIs were 9.0 or higher [19 ] These...
Ngày tải lên: 09/08/2014, 06:22
Báo cáo y học: " Genome-wide analysis of host-chromosome binding sites for Epstein-Barr Virus Nuclear Antigen 1 (EBNA1)" pot
... NM_0 011 45447 ZNF200 4000 chr16 chr17 32 215 95 717 70850 32 215 96 717 708 51 NM_0 011 45447 NM _18 2565 ZNF200 FAM100B 4000 4000 chr17 13 35740 13 357 41 Motif NM_0 010 80950 MYO1C 500 chr17 58 917 775 58 917 776 ... NM_0 011 34420 CDC7 500 chr1 15 417 0655 15 417 0656 NM_ 014 949 KIAA0907 500 chr10 613 38790 613 387 91 NM_005436 CCDC6 3000 chr 11 64 216 95 64 216 96 NM_000 613 HPX 4000 chr12 67007430 670074 31 NM_ 017 440 MDM1 ... 368723 31 Motif 2.Motif NM_ 015 568 PPP1R16B 5000 chr22 chr3 26645 510 757 616 60 26645 511 757 616 61 NR_026962 NR_0 317 14 LOC284900 MIR1324 500 2000 chr6 18 376590 18 3765 91 chr6 14 9683865 14 9683866 chr6 3 919 014 0...
Ngày tải lên: 12/08/2014, 01:22
Báo cáo khoa học: "Epstein-Barr Nuclear Antigen 1 modulates replication of oriP-plasmids by impeding replication and transcription fork migration through the family of repeat" ppt
... of EBNA1 binding sitesa Colonies per 10 5 live, transfected cells platedb AGP73 AGP74 AGP 212 AGP 213 FR (10 ), DS FR(20), DS FR (10 ), DS, FR (10 ) FR (10 ), FR (10 ), DS) 4390 ± 311 .1c 12 96 ± 10 6.1c 10 048 ... (R01CA 112 564) to AA supported this work References 10 11 Adams A: Replication of latent Epstein- Barr virus genomes in Raji cells J Virol 19 87, 61: 1743 -17 46 Yates JL, Guan N: Epstein- Barr virus- derived ... activation by Epstein- Barr nuclear antigen J Virol 2003, 77 :11 767 -11 780 Sears J, Ujihara M, Wong S, Ott C, Middeldorp J, Aiyar A: The amino terminus of Epstein- Barr Virus (EBV) nuclear antigen contains...
Ngày tải lên: 12/08/2014, 04:21
Báo cáo y học: "Seroprevalence of hepatitis B and C virus in HIV-1 and HIV-2 infected Gambians" pps
... (36.0) 11 7 (78.5) 16 (10 .1) (18 .8) 10 9 (76.8)* HIV-2 (10 .3) (0.0) 24 (85.7) 24 (11 .1) (17 .4) 17 4 (89.2)* Dual Infection P-value difference (5.3) 0.27 (10 0.0) 0 .17 17 (99.4) 0. 21 (11 .1) 0.96 (10 0.0) ... μL -1) * *14 0 ( 210 .0) **649.0 (450.0) 600.0 ( 510 .0) CD4 Count < 200 cells μL -1 17 (58.6) (4.2) 26 (10 .7) 10 (14 .0) 34.0 (10 .0) 33.0 (11 .0) N = 19 1. 60 × 10 5 (3.4 x105) 10 0 (5.8 × 10 3) N = 10 – 14 0.0 ... (50.0) 2.2 × 10 0.83 0. 81 14 (58.3) 2.2 × 10 2 45-93 years P-value difference (33.3) 1. 9 × 10 (40.0) 2.0 × 10 3 0. 31 0.30 0 .12 0.53 ( 21. 4) 1. 1 × 10 4 17 (40.4)* 4.3 × 10 2 (14 .2) (18 .5)* 2 .1 × 10 3 HIV...
Ngày tải lên: 12/08/2014, 01:21
Báo cáo y học: "Association between anti-nucleophosmin and anti-cardiolipin antibodies in (NZW × BXSB)F1 mice and human systemic lupus erythematosus" doc
... References 10 11 12 13 14 15 16 17 18 19 20 R1403 Hang LM, Izui S, Dixon FJ: (NZW × BXSB)F1 hybrid A model of acute lupus and coronary vascular disease with myocardial infarction J Exp Med 19 81, 15 4: 216 -2 21 ... ± 11 .5 Females 73 (89.0) 18 * 55 Males (10 .8) 5* aCL 32 (39) 15 (65.2)** 17 (28.8)** ANA-positive 66 (80.5) 23 (10 0) 43 (72.8) Anti- DNA 46 (56) 13 (56.5) 33 (55.9) Anti- β2GPI 15 (18 .3) ( 21. 7) 10 ... by the presence of anti- nucleolar antibodies, had anti- NPM and aCL antibodies and SLE However, our results, showing that anti- NPM antibodies are constantly detected in WB mice and frequently observed...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo khoa học: "Epstein-Barr virus latent membrane protein-1 (LMP-1) 30-bp deletion and Xho I-loss is associated with type III nasopharyngeal carcinoma in Malaysia" docx
... 0 .15 8 1/ 10 (10 .0) 0.363 14 /19 (73.7) Malay vs Chinese, p = 0.046* 3 /11 (27.3) 0.689 3 /14 ( 21. 4) Malay vs India, p = 1. 000 16 /17 (94 .1) Malay vs Chinese, p < 0.050* 16 /18 (88.9) 5 /17 (29.4)Ø 7 /17 ... (64.7)§ 0.289 4 /15 (26.7) 2 /11 (18 .2)∞ 1. 000 12 /15 (80.0) 19 / 21 (90.5)∂ 0.630 4 /16 (25.0) 5 /10 (50.0)Ω 0.234 6 /13 (46.2) 11 /16 (68.8)Φ 0.274 3 /15 (20.0) Malay vs India, p = 1. 000 Malay vs Chinese, ... NKC, p = 1. 000 5 /12 ( 41. 7) SCC vs UC, p = 0. 011 * 2/6 (33.3) SCC vs UC, p = 1. 000 14 /16 (87.5) SCC vs UC, p = 0.006* 4/6 (66.7) SCC vs UC, P = 1. 000 5 /12 ( 41. 7) SCC vs UC, p = 0.0 61 13 /16 ( 81. 3) NKC...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo khoa học: Fast set-up of doxycycline-inducible protein expression in human cell lines with a single plasmid based on Epstein– Barr virus replication and the simple tetracycline repressor ppt
... intensity was 19 5 in the off-state and 18 60 in 786 Doxycycline – Relative background transcription (%) 0. 014 0. 014 0.0 011 0.0052 0.045 0.0 017 0.068 0.0077 0.0 31 0. 012 1. 4 1. 6 0.096 0.33 1. 9 0.22 3.4 ... from Epstein Barr virus in various mammalian cells Nature 313 , 812 – 815 Lupton S & Levine AJ (19 85) Mapping genetic elements of Epstein Barr virus that facilitate extrachromosomal persistence of Epstein Barr ... Natl Acad Sci USA 10 2, 5256–52 61 10 Lang Z & Feingold JM (19 96) An autonomously replicating eukaryotic expression vector with a tetracyclineresponsive promoter Gene 16 8, 16 9 17 1 11 Bornkamm GW,...
Ngày tải lên: 23/03/2014, 09:21
Báo cáo hóa học: " Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinom" pot
... http://www.translational-medicine.com/content/8 /1/ 30 Page of Table 1: Correlation between LMP1 and mTOR signaling pathway genes in NPC LMP1 expression Low Case Low 60 54 11 4 High 19 86 10 5 Low 57 58 11 5 High 22 81 103 Low 49 44 ... vs ≥ 46) 1. 7 21 1.085-2.729 0.0 21* Univariate analysis WHO type (I vs IV) 1. 025 0. 618 -1. 700 0.925 Clinical stage (I + II vs III + IV) 1. 824 1. 012 -3.286 0.045* T stage (T1~2 vs T3~4) 1. 5 71 0.972-2.540 ... high) 1. 274 0.796-2.040 0. 314 p-P70S6K expression (low vs high) 1. 447 0.907-2.309 0 .12 1 p-4EBP1 expression (low vs high) 1. 920 1. 154-3 .19 5 0. 012 * Gender (male vs female) 0.447 0.234-0.8 51 0. 014 *...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " Quantitative profiling of housekeeping and Epstein-Barr virus gene transcription in Burkitt lymphoma cell lines using an oligonucleotide microarray" docx
... 0. 01 0 .12 0. 51 1.46 2.03 1. 26 2.08 1. 92 2.08 1. 00 0.25 0.20 0.00 0.32 0. 01 0.09 0. 01 0 .18 0.49 0 .14 0.00 0.25 0. 01 0.05 0.00 0 .18 0.75 1. 04 1. 35 1. 18 1. 35 1. 35 1. 35 1. 29 0 .10 0 .15 0.04 0 .11 0.04 ... expression 1. 73 0.04 0.02 1. 68 0.28 0 .17 1. 21 0.07 0.06 2.28 0.23 0 .10 0.78 0 .13 0 .16 1. 72 0.24 0 .14 1. 34 0. 01 0.00 1. 49 0.46 0. 31 1.69 0.02 0. 01 1.00 0.24 0.24 1. 42 0.04 0.02 1. 16 0.05 0.05 1. 65 0. 01 ... CS 11 21 416 82.4 60.0 CS 70 16 76 903 82.4 60.0 CS Hs .11 8786 70 19 29 15 4 78.8 51. 4 CS 384D8-2.2 Hs.356523 71 22 81 334 80.6 52.2 CS Hs .11 8786 70 19 29 15 4 78.8 51. 4 CS PSMD2 Hs.74 619 70 2828 12 2...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo y học: "Epstein–Barr virus and rheumatoid arthritis: is there a link''''" docx
... to Epstein- Barr virus and tumorrelated antigens J Natl Cancer Inst 19 76, 57 :10 51- 1056 12 2 Shimizu N, Yamaki M, Sakuma S, Ono Y, Takada K: Three Epstein- Barr virus (EBV)-determined nuclear antigens ... References 10 11 12 13 14 15 16 17 18 19 20 21 Gabriel SE, Crowson CS, O’Fallon WM: The epidemiology of rheumatoid arthritis in Rochester, Minnesota, 19 55 19 85 Arthritis Rheum 19 99, 42: 415 -420 Linos ... IgG, IgA [11 3 ,11 4] ↑ ↑ [82-86 ,12 2] EA, EBV early antigen; EA-D, EBV early antigen – diffuse; EA-R, EBV early antigen – restricted; EBNA, EBV nuclear antigen; VCA, EBV viral capsid antigen aAbnormalities...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "Effect of methotrexate and anti-TNF on Epstein-Barr virus T-cell response and viral load in patients with rheumatoid arthritis or spondylarthropathies" ppt
... peptides (n = 11 3, P = 0. 017 , R = 0. 21) (Figure 4), to latent-cycle peptides (P = 0.035, R = 0 .16 ) and to lytic-cycle peptides (P = 0. 011 , R = 0 .16 ) (data not shown) Unadapted Epstein- Barr virus- specific ... 611 RLRAEAQVK A 11 EBNA3B 399 to 408 AVFDRKSDAK A 11 EBNA3B 416 to 424 IVTDVSVIK A 11 LMP2 340 to 350 SSCSSCPLSKI A23 LMP2 13 1 to 13 9 PYLFWLAAI A24 EBNA3A 246 to 253 LYSIFFDY A24 LMP2 419 to 427 TYGPVFMCL ... at week 12 Available online http://arthritis-research.com/content /11 /3/R77 Figure virus- specific T-cell response Correlation between the Epstein- Barr virus viral load and Epstein- Barr virus- specific...
Ngày tải lên: 09/08/2014, 14:21
báo cáo khoa học: "Co-existence of acute myeloid leukemia with multilineage dysplasia and Epstein-Barr virus-associated T-cell lymphoproliferative disorder in a patient with rheumatoid arthritis: a case report" docx
... pattern, i.e., anti -Epstein- Barr virus- viral capsid antigen (VCA) IgM
Ngày tải lên: 10/08/2014, 22:20
Báo cáo y học: " Systemic Epstein-Barr-virus-positive T cell lymphoproliferative childhood disease in a 22-year-old Caucasian man: A case report and review of the literature" docx
... June 2 011 Published: June 2 011 References Straus SE, Cohen JI, Tosato G, Meier J: NIH conference Epstein- Barr virus infections: biology, pathogenesis, and management Ann Intern Med 19 93, 11 8:45-58 ... disorders American journal of clinical pathology 19 93, 99:265-276 doi :10 .11 86 /17 52 -19 47-5- 218 Cite this article as: Tabanelli et al.: Systemic Epstein- Barr -virus- positive T cell lymphoproliferative ... Tabanelli et al Journal of Medical Case Reports 2 011 , 5: 218 http://www.jmedicalcasereports.com/content/5 /1/ 218 Page of Table Cases of systemic Epstein- Barr virus positive (EBV+) T cell lymphoproliferative...
Ngày tải lên: 10/08/2014, 23:21
Báo cáo y học: "Primary effusion lymphoma associated with Human Herpes Virus-8 and Epstein Barr virus in an HIV-infected woman from Kampala, Uganda: a case repor" pptx
... 900 W 1: 3 CD38 SPC32 Novocastra EDTA 750 W 1: 10 1: 10 § CD79a JCB 117 Prof D Mason EDTA 750 W HHV8 13 B10 Menarini EDTA 750 W 1: 10 CD138 - Neomarkers EDTA 900 W 1: 20 Ki-67 Mib -1 Dako EDTA 900 W 1: 20 ... × 10 3/μL 4 -11 × 10 3/μL Neutrophils 62.5% 45-70% Lymphocytes 22.0% 20-40% Monocytes 14 .4% Platelets 3 -10 % 219 × 10 /μL 15 0-400 × 10 3/μL Haemoglobin 6.8 g/Dl 12 -18 g/dL CD4 cell count 12 7/μL 410 -15 90/μL ... 2006, 355 (13 ) :13 31- 1338 11 Cool C, Bitter M: The malignant lymphomas of Kenya; morphology, immunophenotype, and frequency of Epstein- Barr virus in 73 cases Hum Pathol 19 97, 28(9) :10 26 -10 33 12 Lazzi...
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: " Measurement of Epstein-Barr virus DNA load using a novel quantification standard containing two EBV DNA targets and SYBR Green I dye" pps
... 1, 000 20. 31 23.85 10 ,678 1, 133 1, 207 12 9 10 .00% 16 .00% 11 . 31 11. 41 100 27.65 10 2 3.00% 3.90 10 31. 42 10 17 .88% 0.998 18 .95 BHRF -1 Intra-Assay Variation (same day) 10 0,000 17 .23 97,884 9 ,14 4 8.08% ... 26.34 1, 000 25. 21 1,057 10 0 7.00% 9.50 10 0 29 .10 10 3 38 32 .12 % 37.25 10 32. 91 11 46 .16 % 0.9 91 57.50 EBNA -1 Intra-Assay Variation (different days) 10 0,000 16 .94 89,643 8 ,16 4 11 .00% 9 .11 10 ,000 1, 000 ... 10 1,644 14 ,058 10 .99% 28.35 10 ,000 23.75 10 ,660 1, 4 71 13.65% 13 .80 1, 000 27.68 1, 084 19 1 18 .67% 17 .60 10 0 31. 71 111 49 33.58% 43.75 10 35.86 12 65.03% 0.990 75.85 BHRF -1 Inter-Assay Variation 10 0,000...
Ngày tải lên: 12/08/2014, 01:22
Báo cáo y học: "Sequence analysis of the Epstein-Barr virus (EBV) BRLF1 gene in nasopharyngeal and gastric carcinomas" docx
... 10 4238 10 4237 10 4236 10 4073 10 4072 10 40 71 104055 10 4054 10 4053 10 3977 10 3976 10 3975 10 3968 10 3967 10 3966 10 3944 10 3943 10 3942 10 3749 10 3748 10 3747 10 3 719 10 3 718 10 3 717 10 3698 10 3697 10 3696 10 3560 10 3559 ... http://www.virologyj.com/content/7 /1/ 3 41 Nucleotide BRLF1 subtype B95-8 GD1 C666 -1 542 496 489 479 414 406 403 377 3 71 316 292 288 284 273 10 4367 10 4366 10 4365 10 4334 10 4333 10 4332 10 4322 10 43 21 104320 10 4 310 10 4309 10 4308 10 4238 ... 38(66.7%) 9(32 .1% ) 316 (K-E) 18 (52.9%) 38(66.7%) 9(32 .1% ) 377(A-E) 11 (32.3%) 20(35 .1% ) 18 (64.3%) 489(Q-K) 10 (29.4%) 11 (19 .3%) 9(32 .1% ) 1( 3.6%) 489(Q-R) 16 (47 .1% ) 25(43.9%) 15 (53.6%) 542(S-N) 21( 61. 8%)...
Ngày tải lên: 12/08/2014, 02:20
The development of an in vivo humanized mouse model to investigate epstein barr virus infection and tumorigenesis
... INTRODUCTION 1. 1 Epstein- Barr virus life cycle 1. 2 EBV and the immune system 1. 2 .1 1.2.2 CD4+ helper T cell responses .6 1. 2.3 EBV and NK cells 1. 2.4 EBV and the human ... system 1. 2.5 Anti- EBV antibody responses 11 1. 2.6 1. 3 CD8+ cytotoxic T cell (CTL) responses .5 Immune evasion mechanisms of EBV .12 Latent EBV infection 15 1. 3 .1 1.3.2 Latency ... neutralizing antibodies in acute IM 42 Thus by the onset of clinical symptoms, high titers of anti- viral capsid antigen IgM and IgG as well as IgG against early antigen and membrane antigen complexes...
Ngày tải lên: 10/09/2015, 09:22
Epstein barr virus episome replication and transcription
... plasmids 63 4 .1. 1 .1 Amplification of oriP DNA 63 4 .1. 1.2 pcDNA 3 .1+ 65 4 .1. 1.3 p-oriP-S 66 4 .1. 1.4 p-S-oriP and p-S-oriP .1 67 4 .1. 1.5 p-oriP-∆S 70 iv 4 .1. 2 Replication of p-oriP-S in EBNA -1 expressing ... Saccharomyces cerevisiae 10 2 .1. 2.2 Origin of replication in Drosophilia melanogaster 12 2 .1. 2.3 Origin of replication in mammalian cells 14 2.2 Epstein- Barr Virus 17 2.2 .1 Epstein- Barr Virus latent origin ... origin of replication oriP and the viral nuclear antigen, EBV Nuclear Antigen- 1 (EBNA -1) OriP contains multiple EBNA -1 binding sites, and with the help of bound EBNA -1, help recruit cellular proteins...
Ngày tải lên: 05/10/2015, 21:24
Nghiên cứu và thử nghiệm hạt từ nano được chức năng hóa bề mặt trong chẩn đoán virus epstein barr
... M10 Mgsi 26,78 1. 18x106 M10 I 27,73 7.04x105 Từ kết real-time PCR ta thấy số ADN EBV tách theo kít Virus Magnet Nano Kit hai mẫu 10 tƣơng ứng M7 Mgsi =7 .17 x103, M10 Mgsi = 1. 18x106 copies/ml cao ... bảng 3 .1 Bảng 3 .1: Kết real–time PCR định lượng ADN EBV tách ba kít Mẫu CT (chu kỳ ngƣỡng) Số copies/ml M7 Q 35.6 9,64x103 M7 Mgsi 36.2 7 ,17 x103 M7 I 40.62 6,53x102 M10 Q 25,96 1. 84x106 M10 Mgsi ... Epstein barr virus , 21- 37 14 Elisabeth S., Aravind P (2007), BioNanotechnology 1st edit., Morgan & Claypool , Conecticut, USA, 31- 79 15 Epstein MA., Barr YM ADN Achong BG (19 64), Virus particles...
Ngày tải lên: 10/02/2014, 20:38
Nghiên cứu chẩn đoán lâm sàng và gen virus epstein - barr trong ung thư vòm mũi họng
... 4,00 1, 00 1, 00 0,00 T3 T4 Tổng n 30 33 26 11 1 200 15 16 ,5 13 55,5 10 0% [10 ,5 20,9] [11 ,8 22,5] [8,8 16 ,6] [48,3 62,5] p p 0,05 p1, p2< 0,05 Bệnh nhân đến khám giai đoạn muộn T3 (13 %), ... n 30 20 14 1 200 % 4,5 15 10 71, 5 10 0% p p1>0,05 p1, p2
Ngày tải lên: 08/04/2014, 13:28