treatment of relapsed acute lymphoblastic leukemia
báo cáo khoa học: " Plasma levels of leptin and soluble leptin receptor and polymorphisms of leptin gene -18G A and leptin receptor genes K109R and Q223R, in survivors of childhood acute lymphoblastic leukemia" docx
Ngày tải lên :
10/08/2014, 10:21
... survivors of childhood acute lymphoblastic leukemia: A report from the childhood cancer survivor study J Clin Oncol 2003, 21:1359-1365 21 Pui CH, Evans WE: Treatment of acute lymphoblastic leukemia ... Survivors of pediatric acute lymphoblastic leukemia (ALL) are at substantially increased risk of developing obesity [3-5] The most common explanations involve late effects of chemo-and radiotherapy, treatment ... reducing the inhibitory effect of the peripheral signal informing of the accumulation of body stores of energy We cannot explain the presence of particular clusters of leptin receptor levels (above...
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Báo cáo y học: " Challenges in implementing individualized medicine illustrated by antimetabolite therapy of childhood acute lymphoblastic leukemia" ppt
Ngày tải lên :
13/08/2014, 13:20
... increase the risk of relapse for some children with acute lymphoblastic leukemia J Clin Oncol 2003, 21:1332-1339 Cunningham L, Aplenc R: Pharmacogenetics of acute lymphoblastic leukemia treatment response ... Long-term results of NOPHO ALL-92 and ALL-2000 studies of childhood acute lymphoblastic leukemia Leukemia 2010, 24:345-354 Schmiegelow K, Bjork O, Glomstein A, et al: Intensification of mercaptopurine/methotrexate ... childhood acute lymphoblastic leukemia N Engl J Med 1998, 338:499-505 17 Erb N, Harms DO, Janka-Schaub G: Pharmacokinetics and metabolism of thiopurines in children with acute lymphoblastic leukemia...
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báo cáo hóa học: " Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: an exploratory study" pdf
Ngày tải lên :
20/06/2014, 15:20
... al.: Impaired sleep affects quality of life in children during maintenance treatment for acute lymphoblastic leukemia: an exploratory study Health and Quality of Life Outcomes 2011 9:25 Submit ... ALL: Acute lymphoblastic leukemia; CHQ: Child Health Questionnaire; CSHQ: Children’s Sleep Habits Questionnaire; IQR: Inter quartile range; PedsQL: Pediatric Quality of Life Inventory 3.0™ Acute ... Rothney M, Feeny D: Health-related quality of life during post-induction chemotherapy in children with acute lymphoblastic leukemia in remission: An influence of corticosteroid therapy Int J Oncol...
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CLINICAL EPIDEMIOLOGY OF ACUTE LYMPHOBLASTIC LEUKEMIA - FROM THE MOLECULES TO THE CLINIC docx
Ngày tải lên :
17/03/2014, 12:20
... infections and risk of acute lymphoblastic leukemia in the offspring American journal of epidemiology 2003;158(3) 207-213 Infectious Etiology of Childhood Acute Lymphoblastic Leukemia, Hypotheses ... experience and the risk of childhood acute lymphoblastic leukemia American journal of epi‐ demiology 2000; 152(5):1136-44 Model for Identifying the Etiology of Acute Lymphoblastic Leukemia in Children ... Epidemiology of Acute Lymphoblastic Leukemia - From the Molecules to the Clinic Figure Interaction among the three phenomena Acute lymphoblastic leukemia (AL) in childhood is the result of the interactions...
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báo cáo hóa học: " Health-related quality of life assessment in Indonesian childhood acute lymphoblastic leukemia" potx
Ngày tải lên :
18/06/2014, 19:20
... quality of life in survivors of childhood cancer in Uruguay Pediatr Blood Cancer 2008, 50:838-43 Sutaryo , Sumadiono , Suhadi , et al.: The Protocol of Wijaya Kusuma acute lymphoblastic leukemia of ... coping with the disease and its treatment Abbreviations ALL: acute lymphoblastic leukemia; HRQOL: healthrelated quality of life; PedsQL™: the Pediatric Quality of Life Inventory™ Competing interests ... Childhood acute lymphoblastic leukaemia – current status and future perspectives Lancet Oncol 2001, 2:597-607 Pui CH, Jeha S: New therapeutic strategies for the treatment of acute lymphoblastic...
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báo cáo hóa học:" Health-related quality of life assessment in Indonesian childhood acute lymphoblastic leukemia" docx
Ngày tải lên :
20/06/2014, 16:20
... quality of life in survivors of childhood cancer in Uruguay Pediatr Blood Cancer 2008, 50:838-43 Sutaryo , Sumadiono , Suhadi , et al.: The Protocol of Wijaya Kusuma acute lymphoblastic leukemia of ... coping with the disease and its treatment Abbreviations ALL: acute lymphoblastic leukemia; HRQOL: healthrelated quality of life; PedsQL™: the Pediatric Quality of Life Inventory™ Competing interests ... Childhood acute lymphoblastic leukaemia – current status and future perspectives Lancet Oncol 2001, 2:597-607 Pui CH, Jeha S: New therapeutic strategies for the treatment of acute lymphoblastic...
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Báo cáo khoa học: "Mitochondrial DNA alterations of peripheral lymphocytes in acute lymphoblastic leukemia patients undergoing total body irradiation therapy" ppt
Ngày tải lên :
09/08/2014, 09:21
... Comparison of intensive chemotherapy, allogeneic or autologous stem cell transplantation as post-remission treatment for adult patients with high-risk acute lymphoblastic leukemia Final results of the ... rate of 4.5-4.9 cGy/min over two successive days None of the patients had prior exposure to any cytotoxic treatment for at least weeks before the start of radiotherapy All patients had ml of PB ... alterations of peripheral lymphocytes in acute lymphoblastic leukemia patients undergoing total body irradiation therapy Quan Wen1, Yide Hu1§, Fuyun Ji2, Guisheng Qian2 Third Department of Oncology,...
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báo cáo khoa học: "Persistence of TEL-AML1 fusion gene as minimal residual disease has no additive prognostic value in CD 10 positive B-acute lymphoblastic leukemia: a FISH study" doc
Ngày tải lên :
10/08/2014, 22:20
... Journal of Hematology & Oncology 2008, 1:17 Background Acute lymphoblastic leukemia (ALL) is the most common malignancy of childhood Cure of many of these children is difficult ... Study Group for Adult Acute Lymphoblastic Leukemia: Clinical significance of minimal residual disease quantification in adult patients with standard-risk acute lymphoblastic leukemia Blood 2006, ... childhood acute lymphoblastic leukemia: analysis of patients in continuous complete remission or with consecutive relapse Leukemia 1992, 6:282-288 Potter MN, Steward CG, Oakhill A: The significance of...
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báo cáo khoa học: "Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia" doc
Ngày tải lên :
10/08/2014, 22:21
... Heerema NA: Biology and treatment of childhood T-lineage acute lymphoblastic leukemia Blood 1998, 91:735-746 Morris JC, Waldmann TA, Janik JE: Receptor-Directed Therapy of T-Cell Leukemias and Lymphomas ... article as: Huang et al.: Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia Journal of Hematology & Oncology 2010 3:44 ... amounts of the genes of interest and the b2M reference gene were measured in two independent assays The 2(-ΔΔCT) method was used to present the data of the genes of interest Huang et al Journal of...
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báo cáo khoa học: " FCR (Fludarabine, Cyclophosphamide, Rituximab) regimen followed by 90yttrium ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma: a report of 9 cases" pot
Ngày tải lên :
10/08/2014, 10:21
... al reported an incidence of t-MDS and t-AML (treatment- related acute myeloid leukemia) after 90 Y-RIT of 0.3% per year after the diagnosis of NHL and 0.7% per year after treatment Most patients ... analysis Treatment Patients at relapse had received cycles of FCR: fludarabine at a dose of 25 mg/m2 i.v on days to 3; cyclophosphamide at a dose of gr/m2 i.v on day and rituximab Page of at a dose of ... population composed mainly of patients with a history of prior treatment using rituximab plus chemotherapy A longer follow up and a larger number of patients with relapsed grades and FL are required...
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báo cáo khoa học: "SET-NUP214 fusion in acute myeloid leukemia- and T-cell acute lymphoblastic leukemia-derived cell lines" ppsx
Ngày tải lên :
10/08/2014, 22:20
... translocation breakpoint sequences of two DEK-CAN fusion genes present in t(6;9) acute myeloid leukemia and a SET-CAN fusion gene found in a case of acute undifferentiated leukemia Genes Chromosomes ... reported in a single case of acute myeloid leukemia (AML) [5] SETNUP214 positive T-ALL patients exhibited high expression levels of HOXA cluster genes [4] Downregulation of the fusion gene repressed ... Grosveld GC: SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoetic progenitors and hyperproliferation of stomach mucosa in transgenic mice...
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Báo cáo y học: " Precursor B-cell acute lymphoblastic leukemia presenting as obstructive jaundice: a case report" pdf
Ngày tải lên :
10/08/2014, 23:21
... mass: a rare presentation of acute lymphoblastic leukaemia in an adult JOP 2010, 11:72-74 Takamatsu T: Preferential infiltration of liver sinusoids in acute lymphoblastic leukemia Rinsho Ketsueki ... precursor B-cell acute lymphoblastic leukemia Page of major contributor to the Discussion section NA was involved in the patient’s care (as an oncology fellow) and supervised the drafting of the manuscript ... function test results in acute leukemia Ann Pharmacother 2005, 39:1752-1754 doi:10.1186/1752-1947-5-269 Cite this article as: Siddique et al.: Precursor B-cell acute lymphoblastic leukemia presenting...
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Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report." doc
Ngày tải lên :
11/08/2014, 03:21
... concurrent presence of radiation, so the proof of efficacy and superiority of TMZ has led to a paradigm shift in the management of aggressive CNS gliomas [1] Although the recommended treatment- cycle ... mutagenic risk potential for development of myeloid leukemia, but not for lymphoblastic leukemia TMZ is a new alkylating agent; its safety profile and lack of data on any mutagenic potential has ... subsequent to the use of TMZ Some case reports exist of myelodyplasia rapidly transforming in undifferentiated leukemia [3,5] and one report of Ph negative T-ALL in a patient receiving treatment [6]...
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Báo cáo y học: "Acute lymphoblastic leukemia subsequent to temozolomide use in a 26-year-old man: a case report" potx
Ngày tải lên :
11/08/2014, 07:20
... concurrent presence of radiation, so the proof of efficacy and superiority of TMZ has led to a paradigm shift in the management of aggressive CNS gliomas [1] Although the recommended treatment- cycle ... mutagenic risk potential for development of myeloid leukemia, but not for lymphoblastic leukemia TMZ is a new alkylating agent; its safety profile and lack of data on any mutagenic potential has ... subsequent to the use of TMZ Some case reports exist of myelodyplasia rapidly transforming in undifferentiated leukemia [3,5] and one report of Ph negative T-ALL in a patient receiving treatment [6]...
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CD137L signalling induces differentiation of primary acute myeloid leukemia cells
Ngày tải lên :
09/09/2015, 11:15
... to God, with whom all things are possible ii TABLE OF CONTENTS SUMMARY vii LIST OF TABLES viii LIST OF FIGURES ix LIST OF ABBREVIATIONS xi LIST OF PUBLICATIONS xiv INTRODUCTION 1.1 CD137 biology ... differentiation of the transformed myeloid cells in acute myeloid leukaemia Primary acute myeloid leukaemia blasts isolated from either the bone marrow or peripheral blood of patients at time of diagnosis ... developed 1.6 Acute myeloid leukaemia Acute myeloid leukaemia (AML) is a cancer of the myeloid lineage of white blood cells, characterized by arrested myelopoiesis and over-proliferation of clonal,...
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Relapse prediction in childhood acute lymphoblastic leukemia by time series gene expression profiling
Ngày tải lên :
10/09/2015, 15:50
... tool in leukemia diagnosis The diagnosis of leukemia refers to 1) the confirmation of a leukemia case, and 2) the identification of the subtype of a leukemia case A recent study, consisting of over ... samples of MILE-AML and MILE-NBM, respectively The GSS of relapses are shown in the figure 96 x LIST OF ABBREVIATION ALL Acute Lymphoblastic Leukemia AML Acute Myeloid Leukemia ... CHILDHOOD ACUTE LYMPHOBLASTIC LEUKEMIA BY TIME-SERIES GENE EXPRESSION PROFILING DIFENG DONG (B COMP., FUDAN UNIVERSITY) A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF COMPUTER...
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Báo cáo y học: "The impact of therapy for childhood acute lymphoblastic leukaemia on intelligence quotients; results of the risk-stratified randomized central nervous system treatment trial MRC UKALL XI" ppsx
Ngày tải lên :
10/08/2014, 21:23
... start of treatment, gender and number of previous tests taken In addition, examining the proportion of patients with an IQ < 80 showed no differences by treatment allocation (data not shown) Treatment ... differences of 10 points These results were unchanged when allowing for age at the start of treatment, gender, and the number of previous tests taken Again, analysis of the proportion of patients ... 18(3):319-338 Kaleita TA: Central nervous system-directed therapy in the treatment of childhood acute lymphoblastic leukemia and studies of neurobehavioral outcome: Children’s Cancer Group trials Curr...
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Báo cáo y học: "A meta-analysis of CAG (cytarabine, aclarubicin, G-CSF) regimen for the treatment of 1029 patients with acute myeloid leukemia and myelodysplastic syndrome" ppsx
Ngày tải lên :
10/08/2014, 21:23
... EH: Treatment of relapsed and refractory acute myelogenous leukemia Leukemia 2000, 14(3):476-479 Gregory TK, Wald D, Chen Y, Vermaat JM, Xiong Y, Tse W: Molecular prognostic markers for adult acute ... H, McIntyre OR, Schiffer C: A comparative study of two different doses of cytarabine for acute myeloid leukemia: a phase III trial of Cancer and Leukemia Group B Blood 1991, 78(10):2520-2526 31 ... CR rate of CAG was significantly higher than those of other regimens, with an odds ratio of 2.43 (95% CI, 1.52-3.88) (Figure 5) Cardiotoxicity and early death rate of CAG The toxicity of CAG in...
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báo cáo khoa học: "A homoharringtonine-based induction regimen for the treatment of elderly patients with acute myeloid leukemia: a single center experience from China" pptx
Ngày tải lên :
10/08/2014, 22:20
... therapy in patients 61 years or older with acute myeloid leukemia in first remission: results of second randomization of the AML HD98-B treatment Trial Leukemia 2006, 20:748-750 Olivieri A, Capelli ... method using the SPSS 13.0 software Results Characteristics of the patients Characteristics of the patients at the time of diagnosis are listed in Table The median age of these patients was 70 (60–84) ... response (OR) of 56.5% (13/23) Page of (page number not for citation purposes) Journal of Hematology & Oncology 2009, 2:32 http://www.jhoonline.org/content/2/1/32 Table 1: Clinical data of 23 patients...
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In vitro and in vivo study of ABT 869 in treatment acute myeloid leukemia (AML) alone or in combination with chemotherapy or HDAC inhibitors insight into molecular mechanism and biologic characterization
Ngày tải lên :
11/09/2015, 09:06
... including acute lymphoblastic leukemia, 6 acute myeloid leukemia, 7,8 myelodysplastic syndromes (MDS),9 chronic leukemias,10,11 lymphoma12,13 and multiple myeloma (MM).12,14 In AML, a number of studies ... Antileukemic effect of combination of ABT-869 with SAHA or VPA on leukemia cell lines with FLT3-ITD mutations 89 Figure 4.2 Western blot analysis of acetylation of H3, H4 and expression of p21, cleaved ... M.sc National University of Singapore) A THESIS SUBMITTED FOR THE DEGREE OF DORCTOR OF PHILOSOPHY DEPARTMENT OF MEDICINE YONG LOO LIN SCHOOL OF MEDICINE NATIONAL UNIVERSITY OF SINGAPORE Singapore...
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