transforming growth factor beta1 beta2 beta3 and tgfalpha

báo cáo hóa học:" Enhanced serum concentrations of transforming growth factor-beta1 in simple fatty liver: is it really benign?" pot

Ngày tải lên : 18/06/2014, 15:20

... ng/mL 600 700 Association between serum TGF-β1 and ferritin Figure Association between serum TGF-β1 and ferritin TGF-β1, transforming growth factor- beta1 To let us get down to the grassroots of ... (NASH) and also of the severity of fibrosis in NASH J Gastroenterol 2007, 42:573-82 Khan R, Sheppard R: Fibrosis in heart disease: understanding the role of transforming growth factor- beta1 in ... reactive protein; TGF-β1, transforming growth factor beta1; BMI, body mass index; US score, hepatic steatosis score at ultrasound; r, Pearson's correlation coefficient and rho, Spearman's rank...

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Báo cáo y học: "β Transforming growth factor-β-induced regulatory T cells referee inflammatory and autoimmune diseases" potx

Ngày tải lên : 09/08/2014, 06:22

... TGF-β signaling and regulation TGF-β is a potent cytokine and growth factor whose biological activity is primarily regulated post-translationally [30], because it is transcribed and translated ... CD4+CD25+ regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness J Exp Med 2002, 196:237-246 Chen W, Jin W, Hardegen N, ... D, Geiser A, Lyght M, Flanders KC, Roberts AB, Sporn MB, Ward JM, Karlsson S: Transforming growth factor β1 null mutation in mice causes excessive inflammatory response and early death Proc Natl...

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Báo cáo y học: " Aging, osteoarthritis and transforming growth factor-β signaling in cartilage" pps

Ngày tải lên : 09/08/2014, 07:20

... employed TGF-β isoforms 1, 2, and 3, TGF-β receptors I and II, Smads 2, 3, 4, 6, and 7, and phosphorylated Smad (Smad-2P) were localized in the joints of young and old mice In 2-yearold mice ... BMP-2, BMP-7, and growth differentiation factor (GDF-5) GDF-5 is also known as cartilage-derived morphogenetic protein (CDMP 1) and has been implicated in articular cartilage development and maintenance ... homoeostasis, and regeneration Ann Rheum Dis 2003, 62 Suppl 2:ii73-ii88 Davidson ENB, Schartstuhl A, Vitters EL, van der Kraan PM, van der Berg WB: Reduced transforming growth factorbeta signaling...

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Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx

Ngày tải lên : 09/08/2014, 08:22

... PE: Transforming growth factor beta in renal allograft recipients Transplantation 1994, 57:1727-1731 16 Coupes BM, Williams S, Roberts IS, Short CD, Brenchley PE: Plasma transforming growth factor ... 16:137-161 Geiser AG, Letterio JJ, Kulkarni AB, Karlsson S, Roberts AB, Sporn MB: Transforming growth factor- beta1 (TGF -beta1) controls expression of major histocompatibility genes in the postnatal ... TGFbeta1 act synergistically to promote activation of the vascular endothelium and formation of lipid lesions J Cell Sci 2000, 113:2355-2361 Mallat Z, Tedgui A: The role of transforming growth factor...

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Báo cáo y học: "Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling" pot

Ngày tải lên : 09/08/2014, 10:21

... interacts with and influences the effects of key bone regulators insulin-like growth factor (IGF)1 and transforming growth factor (TGF)-β [93,94] STC1 Stanniocalcin inhibits calcium uptake and has inhibitory ... increased insulin-like growth factor types I and II and transforming growth factor beta in cortical bone from the iliac crest Possible mechanism of increased bone density and protection against ... insulin-like growth factor- 1, insulin-like growth factor- 2 and TGF-β1 in cortical bone from the iliac crest [38]; matrix metalloproteinase (MMP)2 and liver alkaline phosphatase in subchondral bone [4]; and...

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Báo cáo y học: "Adipose-derived mesenchymal stem cells from the sand rat: transforming growth factor beta and 3D co-culture with human disc cells stimulate proteoglycan and collagen type I rich extracellular matrix" ppsx

Ngày tải lên : 09/08/2014, 10:23

... of the transforming growth factorbeta (TGFβ) super family such as the TGFβ isoforms and the BMPs [15] Also important are the fibroblast growth factor isoforms and insulinlike growth factor (IGF-1) ... cells, perhaps through contact or growth factor upregulation leading to increased matrix production TGFβ, IGF-1, epidermal growth factor and platelet-derived growth factor were significantly upregulated ... contributions HEG and ENH conceived the study and participated in its design and co-ordination HT and HEG wrote the manuscript HT, MK and RD performed all experiments and assays HT and RD retrieved...

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Association between transforming growth factor b1 polymorphisms and atrial fibrillation in essential hypertensive subjects pptx

Ngày tải lên : 10/08/2014, 05:21

... Hutchinson IV: Genotypic variation in the transforming growth factor- beta1 gene: association with transforming growth factor- beta1 production, fibrotic lung disease, and graft fibrosis after lung transplantation ... the circulating concentration of transforming growth factor type beta1 Human molecular genetics 1999, 8:93-97 27 Peterson MC: Circulating transforming growth factor beta-1: a partial molecular ... K: Transforming growth factor- beta1 gene polymorphisms and coronary artery disease Clin Sci (Lond) 1998, 95:659-667 25 Xu HY, Hou XW, Wang LF, Wang NF, Xu J: Association between transforming growth...

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Báo cáo y học: "Gender-based reciprocal expression of transforming growth factor-β1 and the inducible nitric oxide synthase in a rat model of cyclophosphamide-induced cystitis" ppsx

Ngày tải lên : 11/08/2014, 08:22

... Nilbert M: Transforming growth factor beta1 in the human endometrium Cyclic variation, increased expression by estradiol and progesterone, and regulation of plasminogen activators and plasminogen ... Latent transforming growth factorbeta activation in mammary gland: regulation by ovarian hormones affects ductal and alveolar proliferation Am J Pathol 2002, 160:2081-2093 Casslen B, Sandberg ... IL-1beta and soluble interleukin-1 receptor antagonist (sIL-1RA) but similar IL-2, sIL2R, IL-3, IL-4, IL-6, sIL-6R, IL-10, tumour necrosis factor (TNF)-alpha, transforming growth factor (TGF)-beta and...

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báo cáo khoa học: " Effects of enamel matrix derivative and transforming growth factor-b1 on human osteoblastic cells" pot

Ngày tải lên : 11/08/2014, 20:21

... healing and regeneration[23] and the association of growth factors seems to synergistically affect the regenerative process[24-27] Because the effects of the association of EMD with growth factors and ... mediated by growth factors found in its composition or in the culture medium modified by cells under EMD exposure[15] The interactions between growth factors and precursor cells are key factors in ... derivative and transforming growth factor- beta1 on human periodontal ligament fibroblasts J Clin Periodontol 2007, 34:514-522 Page of 14 Tokiyasu Y, Takata T, Saygin E, Somerman M: Enamel factors...

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Báo cáo y học: "Bone Morphogenetic Protein (BMP)-4 and BMP-7 regulate differentially Transforming Growth Factor (TGF)-β1 in normal human lung fibroblasts (NHLF)" pdf

Ngày tải lên : 12/08/2014, 11:22

... interstitial fibroblasts is mediated by transforming growth factorbeta1-induced release of extracellular fibroblast growth factor- 2 and phosphorylation of p38 MAPK and JNK J Biol Chem 2005, 280(52):43000-43009 ... UK) and grown at 37°C in a humidified 5% CO2 atmosphere in fibroblast growth medium (FGM, Lonza Rockland Inc, Rockland, ME, USA) supplemented with 0.5 ml recombinant human fibroblast growth factor- B, ... is SMad-dependent and enhanced by fibronectin and TNF-alpha Fibrogenesis & Tissue Repair 2010, 3(2): 14 Schmidt-Weber CB, Blaser K: Regulation and role of transforming growth factorbeta in immune...

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Báo cáo y học: "Platelet-derived growth factor and transforming growth factor beta synergistically potentiate inflammatory mediator synthesis by fibroblast-like synoviocytes" potx

Ngày tải lên : 12/08/2014, 12:20

... and/ or growth factors (10 ng/ml), and supernatants analyzed by ELISA Mean & SEM, n = RA FLS lines Asterisk indicates P < 0.05 between the combination and the added values for TNF alone and growth ... inflammation and hyperplasia induced by transforming growth factor beta J Exp Med 1990, 171:231-247 Kumkumian GK, Lafyatis R, Remmers EF, Case JP, Kim SJ, Wilder RL: Platelet-derived growth factor and ... effects of transforming growth factor- beta1 on gene expression J Biol Chem 1996, 271:16567-16572 31 Heldin CH, Ostman A, Ronnstrand L: Signal transduction via plateletderived growth factor receptors...

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Báo cáo khoa học: Control of transforming growth factor b signal transduction by small GTPases pot

Ngày tải lên : 07/03/2014, 01:20

... & Colicelli J (2008) Integration of transforming growth factor beta and RAS signaling silences a RAB5 guanine nucleotide exchange factor and enhances growth factor- directed cell migration Mol ... signaling during transforming growth factorbeta-induced smooth muscle differentiation J Biol Chem 281, 1765–1770 Deaton RA, Su C, Valencia TG & Grant SR (2005) Transforming growth factor- beta1- induced ... transcription factors and the role of such interactions in the timing and shuttling behavior of Smads remains unexplored [27] One nuclear factor that seems to fulﬁll the criteria for a tethering factor and...

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Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx

Ngày tải lên : 15/03/2014, 11:20

... or inhibit protein synthesis and cell growth [2] The most well deﬁned signaling mechanism regulating mTOR activity in skeletal muscle is the insulin like growth factor- 1 (IGF-1) ⁄ insulin-dependent ... or TSC2 have higher mTOR activity, resulting in a robust cell growth and tumorigenesis [9,10,17,18] Although it is clear that growth factorinduced activation of Akt blocks TSC1 ⁄ TSC2 inhibition ... control, IGF-1 stimulation decreased membrane TSC1 and TSC2 by 36% and 51%, respectively, whereas cytosolic TSC1 and TSC2 increased by 57% and 63%, FEBS Journal 277 (2010) 2180–2191 ª 2010 The...

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Báo cáo khoa học: Fragile X-related protein FXR1 controls posttranscriptional suppression of lipopolysaccharide-induced tumour necrosis factor-a production by transforming growth factor-b1 doc

Ngày tải lên : 22/03/2014, 21:21

... cytokine transforming growth factor- b1 (TGF-b1) of the proinﬂammatory cytokine TNF-a via the induction of FXR1 is the focus of this article TGF-b1, a member of the large transforming growth factor- b ... tumor necrosis factor alpha and transforming growth factor beta during induction of collagen type II arthritis in mice Proc Natl Acad Sci USA 89, 7375– 7379 29 Mendez-Samperio P, Hernandez-Garay ... interleukin-4, transforming growth factorbeta and interleukin-1 beta by peripheral blood mononuclear cells from tuberculosis patients: relationship with the severity of pulmonary involvement Scand J...

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Báo cáo y học: Identiﬁcation of an element within the promoter of human selenoprotein P responsive to transforming growth factor-b ppt

Ngày tải lên : 31/03/2014, 23:20

... expression by transforming growth factor- b1 Mol Pharmacol 59, 716–724 ¨ 22 Dohr, O & Abel, J (1997) Transforming growth factorbeta coregulates mRNA expression of aryl hydrocarbon receptor and 23 24 ... (6710): 491] Nature 394, 909–913 Roberts, A.B & Sporn, M.B (1990) The transforming growth factor- bs In Peptide Growth Factors and Their Receptors I (Sporn, M.B & Roberts, A.B., eds), pp 419–472 ... Harada, J., Tashiro, S., Gotoh Mandeville, R., Maekawa, T & Ishii, S (1999) ATF-2 is a common nuclear target of Smad and TAK1 pathways in transforming growth factorbeta signaling J Biol Chem...

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transforming growth factor-beta protocols

Ngày tải lên : 11/04/2014, 07:14

... B and Roberts, A B (1988) Peptide growth factors are multifunctional Nature 332, 217–219 Roberts, A B and Sporn, M.B (1990) The transforming growth factor betas, in Peptide Growth Factors and ... epidermal growth factor, transforming growth factor, and insulin on DNA and protein synthesis and morphology in serum-free cultures of AKR-2B cells Cancer Res 44, 710–716 34 Anders, R A and Leof, E ... 87–97 26 Koli, K and Keski-Oja, J (1993) Vitamin D3 and calcipotriol enhance the secretion of transforming growth factorbeta and- beta in cultured murine keratinocytes Growth Factors 8, 153–163...

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Báo cáo sinh học: " Liver-spleen axis, insulin-like growth factor-(IGF)-I axis and fat mass in overweight/obese females" pot

Ngày tải lên : 18/06/2014, 22:20

... Correlation between IGF-I zSDS (a and b) and IGFBP-1 (c and d), with HS score at ultrasound (US), and FM% IGF-I zSDS, standard deviation score (SDS) of insulin-like growth factor- I levels according to ... of and/ or between transaminases and UA FM% also correlated positively with HOMA and HS severity IGF-I zSDS and IGFBP-1 correlated negatively with FM% and HS severity at US (Figure 1a, b, c, and ... were 3.4, 3.0, and 1.5% for low, medium, and high points on the standard curve, respectively; inter-assay CVs were 8.2, 1.5, and 3.7% for low, medium, and high points on the standard curve, respectively...

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báo cáo hóa học: " Effect of anti-inflammatory agents on transforming growth factor beta over-expressing mouse brains: a model revised" potx

Ngày tải lên : 19/06/2014, 22:20

... receptor γ ; TGF-β1, transforming growth factor β1, TZD, thiazolidinedione Competing interests Gary Landreth received a honorarium for a talk given to Takeda North America in 2003, and received funding ... western blots and development of the morphometric method to quantitate microglia activation; GL and MH organized and paid for the synthesis and delivery of the chow containing pioglitazone and ibuprofen ... pathogenesis and effects on the ageing and Alzheimer brain Neurol Res 2003, 25:611-616 Wyss-Coray T, Lin C, Sanan DA, Mucke L, Masliah E: Chronic overproduction of transforming growth factor beta-1...

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báo cáo hóa học: " Vascular endothelial growth factor-A (VEGF-A) and chemokine ligand-2 (CCL2) in amyotrophic lateral sclerosis (ALS) patients" ppt

Ngày tải lên : 19/06/2014, 22:20

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báo cáo hóa học:" Liver-spleen axis, insulin-like growth factor-(IGF)-I axis and fat mass in overweight/obese females" docx

Ngày tải lên : 20/06/2014, 04:20

... Correlation between IGF-I zSDS (a and b) and IGFBP-1 (c and d), with HS score at ultrasound (US), and FM% IGF-I zSDS, standard deviation score (SDS) of insulin-like growth factor- I levels according to ... of and/ or between transaminases and UA FM% also correlated positively with HOMA and HS severity IGF-I zSDS and IGFBP-1 correlated negatively with FM% and HS severity at US (Figure 1a, b, c, and ... were 3.4, 3.0, and 1.5% for low, medium, and high points on the standard curve, respectively; inter-assay CVs were 8.2, 1.5, and 3.7% for low, medium, and high points on the standard curve, respectively...

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