trail trail receptors lessons from studies at the molecular level
Báo cáo khoa học: New insights into Fragile X syndrome Relating genotype to phenotype at the molecular level docx
Ngày tải lên :
30/03/2014, 15:20
... kJÆmol)1) The thermal denaturation transition is cooperative (Fig 4C) but irreversible (data not shown) The KH1-KH2(I307N) protein also exhibits cooperative chemical and thermal denaturation transitions ... association of FMRP in RNP particles Thus, despite the fact that the I304N mutation causes Fragile X syndrome, and that investigations of the I304N mutation play a key role in Fragile X research, there ... thio-b-d-galactoside after the cell culthe free energy on denaturant concentration are calculated ture reached attenuance of 0.6–0.7 at 600 nm The growth was continued for additional h at 30 °C The cells were...
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Strong Performers And Successful Reformers In Education Lessons From PISA For The United States doc
Ngày tải lên :
22/03/2014, 16:22
... reflections regarding their findings, interpretations, arguments and the appropriateness of these to the given situations At the next highest level, Level on the PISA mathematics scale, students ... minority status of the students, the nature of the assessments that students must take, the nature of the qualifications they might earn and so on, in great detail In this way, while the causal nature ... of their use of the benchmarking techniques they employed The aim of the American firms was to learn enough from their competitors to beat them at their own game To this, they identified their...
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báo cáo sinh học:" Recent changes in human resources for health and health facilities at the district level in Indonesia: evidence from 3 districts in Java" doc
Ngày tải lên :
18/06/2014, 17:20
... staff, the item that, under Indonesia’s decentralization, has first call on the general allocation fund from the central government Thus, in the absence of a matching increase in the general allocation ... districts, the outcome of a national policy, are likely to be indicative of what happened across the nation They have important implications for the sector as a whole in terms of funding, decentralization, ... coherent approach to improving the performance of the health sector [7] At the same time the health information system is unable to provide the district level information needed to track changes...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_1 pot
Ngày tải lên :
21/06/2014, 08:20
... as the packaging, Jobs controls every other aspect of the customer experience from the TV ads that stimulate desire for Apple’s products, to the museum-like retail stores where customers buy them; ... enigmatic “These things were not mysteries anymore,” he said “[It] became much more clear that they were the results of human creation, not these magical things.”5 Jobs’s birth parents had made attending ... to say your goodbyes.” But later that evening, a biopsy revealed that the tumor was an extremely rare form of cancer that is treatable with surgery Jobs had the operation.8 Now in his early fifties,...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_2 potx
Ngày tải lên :
21/06/2014, 08:20
... successful artists at some point in their careers atrophy: they keep doing what made them successful in the first place, but they don’t evolve “If they keep on risking failure, they’re still artists,” ... out of the papers There are stories—likely apocryphal—of Jobs cornering luckless employees in elevators and quizzing them on their role at the company If the answers weren’t satisfactory, they’d ... some of the most loyal customers of any corporation anywhere If they continued to buy Apple’s machines, they were a great foundation for a comeback The Clones Jobs killed the clone business The move...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_3 pdf
Ngày tải lên :
21/06/2014, 08:20
... unless they can attract talented programmers to create applications for them, just like game consoles are doomed unless they can attract great games From the Mac to the Palm Pilot and the Xbox, the ... suggested that their functions should be illustrated by an animation that was triggered when the mouse cursor hovered over them But then Jobs made what seemed like an odd suggestion: that the buttons ... during which they’d show him their latest mockups For each element of the new interface the menus, the dialogs, the radio buttons—Jobs requested several variations so that he could select the best...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_6 docx
Ngày tải lên :
21/06/2014, 08:20
... sketch on late-night comedy shows, then the ads have graduated from the commercial to the cultural realm Jobs’s association with the ad company began in the early 1980s, when the agency—then known ... celebrating the misfits, the rebels, the troublemakers the crazy ones.” The people who are crazy enough to think they can change the world are the ones that do,” the ad proclaimed The commercial ... from whether there should be fans for cooling machines to the font used on the box But although Jobs is king of the mountain, the decision making at Apple isn’t all top down Argument and debate...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_7 doc
Ngày tải lên :
21/06/2014, 08:20
... collaborators like getting yelled at Or at least, they like the effect it has on their work They appreciate his passion He pushes them to greatness, and, though they might burn out, they learn ... the best way to get creative advertising is to hire the most creative agency Chiat/Day is one of a handful of the most creative agencies in the world, but the real trick is to communicate what ... leaked the information, but lost the case Some speculated that Jobs sued the websites to keep the press in line The lawsuit was seen as press intimidation, a scare tactic designed to intimidate the...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_8 pdf
Ngày tải lên :
21/06/2014, 08:20
... but at the very center of it The computer was the “digital hub,” the central docking station for all the digital devices And by hooking digital devices to the computer, they became enhanced: the ... that people who worked with great intimidators often found the experience “profoundly educational, even transformational.” Jobs works people hard and heaps on the stress, but they produce great ... longer than that “Some people can stick it out for longer than that Avie Tevanian, Bertrand Serlet I’ve seen him screaming at both of them, but they had some way of weathering that There have been...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_9 ppt
Ngày tải lên :
21/06/2014, 08:20
... to go out of their way The store wasn’t located where they did their shopping—in the mall The store was in a remote parking lot At the height of Gateway’s retail operation, when the company owned ... they’ve had and synthesize new things And the reason they were able to that was that they’ve had more experiences or they have thought more about their experiences than other people Unfortunately, ... games There’s no pressure to spend any money, and the staff is happy to answer any question, even the most basic Later on in the evening there’s a class on video editing at a small theater at the...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_10 pot
Ngày tải lên :
21/06/2014, 08:20
... change the way people shopped for technology The retail stores demonstrate Apple’s innovation at work The philosophy, design, and layout came from the digital hub strategy, and the execution from ... some as the best on any platform But, on their own, they have failed to attract new users to the Mac in huge numbers They haven’t proven to be killer apps Nonetheless, as corporate strategy, the ... confident that the Mac can be the hub of this new digital lifestyle by adding value to these other devices.”2 The digital hub is a fresh spin on the old “killer apps” strategy that has long driven the...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_11 pptx
Ngày tải lên :
21/06/2014, 08:20
... where the tech comes from it’s the combination that matters The iPod is more than a sum of its parts • Leverage your expertise Never start from scratch —Apple’s power-supply team fixed the battery, ... aspect of the organization’s functioning, from the food the employees eat to how much they can tell their families about their work, which is pretty much nothing Before Jobs returned to Apple, the ... a software update The update also closed holes that had allowed some iPhone owners—in fact, quite a lot of them—to “unlock” their phones from AT& T’s network and use them with other wireless providers...
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Inside Steve''''s Brain Business Lessons from Steve Jobs, the Man Who Saved Apple by Leander Kahney_13 ppt
Ngày tải lên :
21/06/2014, 08:20
... transformative device Windows compatibility iPhoto iPod advertising as closed platform design of and digital hub concept engineering of evolution of as innovation and iTunes lessons from Steve ... secrecy as theater Mercer, Paul Microsoft Apple innovations, use of investment in Apple OS X, support of patent lawsuit PlaysForSure problems R&D spending vertical integration Windows-compatible ... studio/design team detail orientation of iPod and Ive Jobs design process lessons from Steve Mac MacOS X and manufacturing process materials used motherboard attempt packaging process of QuickTime...
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Identifying common errorss in written english of students of english at the intermediate level
Ngày tải lên :
19/12/2013, 10:39
... shown in the previous chapter that there are various causes leading to the errors in written English of the Vietnamese students of English at the intermediate level Each error is generated from a ... communicative needs and the attitudes towards the second language community If learners want to fulfill their purpose, they will perceive the communicative value of the second language and will therefore ... vocabulary errors These questionnaires (presented in the appendix) intend to find out what common written errors students of English at the intermediate level commit and what the sources of the errors...
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Tài liệu Priority Setting for Reproductive Health at the District Level in the context of Health Sector Reforms in Ghana doc
Ngày tải lên :
13/02/2014, 10:20
... confirms that reproductive health is a “stated” priority at both the national and district levels Priority setting is essentially driven at the national level The study suggests that the national level ... recommendations that are negotiated at the summit The last component of the health summit is the business meeting, which is attended by delegates of the MOH and funding partners It is at the business ... study confirms that reproductive health is a “stated” priority at both the national and district levels But priority setting is essentially driven at the national level the national level sets priorities...
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ICT skills at the intermediate level in South Africa docx
Ngày tải lên :
07/03/2014, 09:20
... the various levels on the education spectrum – higher education and training (HET) at levels 5–8 (skills and competencies at diploma/occupational certificate to doctoral level) ; further education ... education with good mathematics and science results This severely limits the number of candidates that can enter ICT-related fields, where mathematics is usually a requirement Analysis of the ... qualifications at the post-school, pre-higher education level obtained them from private institutions (Moleke, Paterson & Roodt 2003) These providers offered courses that spanned a wide range of levels...
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Báo cáo khoa học: Insulin resistance in human adipocytes occurs downstream of IRS1 after surgical cell isolation but at the 1 level of phosphorylation of IRS1 in type 2 diabetes pot
Ngày tải lên :
07/03/2014, 16:20
... know the details of the molecular dysregulation in the target cells of the hormone Studies of cells from patients with the disease and nondiabetic subjects have demonstrated that mutations in the ... incubation of the cells Incubation for 48 h did not further increase (or decrease) the insulin sensitivity The insulin receptor, the immediate downstream signal mediator IRS1, and the further ... phosphorylation of the insulin receptor and IRS1 was required to increase the phosphorylation of ERK1 ⁄ (Figs 1C and 5) Our findings indicate that the collagenase treatment to isolate adipocytes from the...
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ICT skills at the intermediate level in South Africa pot
Ngày tải lên :
15/03/2014, 02:20
... the various levels on the education spectrum – higher education and training (HET) at levels 5–8 (skills and competencies at diploma/occupational certificate to doctoral level) ; further education ... education with good mathematics and science results This severely limits the number of candidates that can enter ICT-related fields, where mathematics is usually a requirement Analysis of the ... qualifications at the post-school, pre-higher education level obtained them from private institutions (Moleke, Paterson & Roodt 2003) These providers offered courses that spanned a wide range of levels...
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Báo cáo khoa học: "Customizing Parallel Corpora at the Document Level" pot
Ngày tải lên :
17/03/2014, 06:20
... 1993 .The Mathematics of Statistical Machine Translation: Parameter Estimation In Computational Linguistics, 19:263-312 Koehn, P Europarl: A Multilingual Corpus for Evaluation of Machine Translation ... domains? Natural approaches also include choosing the largest corpus available, or using all corpora together Figure shows the effect of these strategies selecting individual documents that match the ... blind feedback Translating the query by taking the dot product between the query vector (with weights from step 1) and a translation matrix obtained by calculating translation probabilities or...
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Báo cáo khoa học: "Automatic Detection of Poor Speech Recognition at the Dialogue Level" potx
Ngày tải lên :
23/03/2014, 19:20
... constructed from rather different feature sets (such as acoustic and lexical features) suggest that there is some redundancy between these feature sets (at least with respect to the task) Fourth, the ... in the literature (to empirically test theoretically motivated proposals) The output of each machine learning experiment is a classification model learned from the training data To evaluate these ... errors resulting from crossvalidation It is clear that performance depends on the features that the classifier has available The BASELINE accuracy rate results from simply choosing the majority class,...
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