... all cases of MM arise from MGUS [55] On the other hand, the majority of MGUS cases will not develop into MM Although the status of M-protein may offer insight into the development of MM, it is ... 'balance' the difference ofthe reporter group; and iii) a peptide reactive group that reacts with the N-terminus of peptides and lysine side chains Labeled samples are then mixed together and analyzed ... increasing the AC amplitude, ions of increasing m/z ratio are ejected and measured by the detector In Time of Flight (TOF), ions of different m/z values are injected into one end ofthe tube so that they...
... inhaled and deposited in the terminal alveoli of another person The likelihood of this is a function ofthe concentration of droplet nuclei containing viable bacilli andthe quantity of infected ... dealing with the case where the infected individuals remain in the exposed class until they either catch multiple infections or die In the steady state ofthe system of equations (2), we have the trivial ... overcoming the immune response and resulting in the onset of disease When mathematical modelling encompasses the natural history of disease (the onset of disease after a long period since the first...
... respect and obey the rules that they But the city’s laws were there before your mother and father, and are therefore equally if not more important than the laws of your mother and father It is ... in the society The voice ofthe latter school is much weaker than the former’s The situation may be partly due to the fact that the view ofthe latter is the view which has been adopted by the ... the world, notably the Civil Rights Movement led by King in the United States andthe Anti-Apartheid Movement in South Africa under the leadership of Nelson Mandela C Martin Luther King and the...
... unified the field of control and communication theory, and defined it with the same title as his book: as the study of control and communication in the animal andthe machine The study of messages, ... that control ofthe media is in the hands ofthe dominant classes who divert them to their own advantage But for Enzensberger and other Marxist theorists, as Baudrillard argues, the media remains ... understand the theoretical framework of participation and in this chapter, I will retrace the concept of participation in the domain of film, art and then demonstrate how some concerns within these...
... between the worlds of ideas andof experimental data The world of ideas includes theories, hypotheses, human knowledge and any other mental constructs, while the world of data consists of experimental ... Most of these have yet to be identied chemically The history of biomedicine as perceived via the awards ofthe Nobel Committee indicates the importance to our understandingofthe subject of both ... describes the networks structure, and has nothing to with structural biology) that denes the participants in the process of interest andthe (qualitative) nature ofthe interactions between them; then...
... Results ofthe link validation Most ofthe synonymy links between candidate terms are detected at the first iteration (383 liens out of 396) The majority ofthe validated links are given by the two ... ofthe line) cofit d'investissement de la ligne (cost of investissement ofthe line) d6clenchement de la ligne (tripping ofthe line) ordre de d~clenchement (order of tripping) de la ligne (of ... hour andthe validation ofthe links has been done in two hours The main difficulty is to evaluate the recall in the results because there is no standard reference in that matter, giving the overall...
... particular, the targets in these plans will needs of current prevention of mother-to-child be expressed in terms ofthe number of Countries will conduct a mapping ofthe transmission of HIV programmes and ... breastfeeding and private sources Countries will regularly their mothers alive period, andthe monitoring ofthe survival revisit resource allocation in light of how of mothers and their retention ... guidelines will be updated the number of their mothers kept alive in the first year ofthe plan Metrics for measuring the survival ofof new HIV infections among children and mothers with HIV will be...
... the formula ofthe Boussinet, then the assumption about the random force will lead, in particular, to the results ofthe work The physical reason ofthe assumption about the uncorrelativity of ... Multiple Meaning SIMULATED MECHANICAL TRANSLATION In the first works on the theory ofthe Brownian movement (see also ) the values ofthe velocity ofthe particle in the various moments ofthe ... uncorrelativity ofthe random force is the shortness of its time ofthe correlation as compared with the time ofthe relaxation ofthe velocity for the large Brownian particles (large frequency ofthe collisions)...
... South and North To the south ofthe bay of Hangzhou, the coast is rocky and indented with many harbours and offshore islands To the north, except along the Shandong and Liaodong peninsulas, the ... °F (10 °C) in North China andthe southern part of Xinjiang, and to 41 °F (5 °C) in the southern area ofthe Northeast, the northern part of Xinjiang, and places near the Great Wall It drops below ... level, is the loftiest highland area in the world The western part of this region, the Qiangtang, has an average height of 16,500 feet (5,000 m) and is known as the “roof ofthe world.” The second...
... design and analysis MM participated in the development ofthe theoretical framework andthe final analysis FR participated in the design ofthe analytical strategy VC participated in the literature ... on the health workforce are quite scarce in the LAC region overall, with the exception of Brazil, Colombia, Mexico, Nicaragua and Peru, andthe initiatives of international collaborations Ofthe ... at a comprehensive situational analysis ofthe status of HRH training andthe labor market, andthe need to expand and/ or reconsider regulations in either area, progress must be made in constructing...
... importance and must be weighted accordingly Their importance varies in function ofthe nature ofthe terminology andofthe text The three criteria are combined by the product ofthe functions, ... illustrate the role ofthe zone while setups (4), (5), and (6) demonstrate the importance ofthe evidence, the proximity, andthe specificity, respectively For the sake of brevity, only the optimal ... However, the specificity andthe proximity are important to improve the identification ofthe terms The size ofthe zone selected to identify the words has an impact on the performance ofthe method...
... defects In addition, Ofut1 and Ofut1R275A both bind the NECD, and expression of Ofut1R275A in cultured cells can increase both the amount andthe ligand-binding activity of secreted NECD [16] ... events and that Ofut1 acts non-catalytically to regulate the exit of Notch from the ER Thus, Ofut1 probably acts as a chaperone in the ER to promote the proper folding ofthe extracellular domain of ... (NECD in green) and is Ofucosylated by Ofut1 (yellow diamond) It is then transported to the plasma membrane and adherens junctions (AJs, cyan) through the Golgi In the absence of Ofut1, Notch remains...
... illustrates the bijection of Theorem 13 Proof (of Theorem 7) The desired conclusion is an immediate consequence of Theorem 13 andthe existence of a parity-reversing involution ρ on the walks w ... (P, Q) of m and with the same shape Theorem [Symmetry Theorem [Ful97, pag 40]] If π is a permutation of [m], then P(π −1 ) = Q(π) and Q(π−1 ) = P(π) The following corollary of Lemma and Theorem ... In the next section we give a sketch and a proof of Theorem Both are straightforward adaptations ofthe proofs in [GWW98] dealing with the r = case In order to motivate the second main result of...
... urticaria, just as the histology ofthe two groups is strikingly similar.27,45 All of these findings provide a basis for further investigation ofthe pathogenesis and treatment of this disease.46–48 ... examined closely.27 The T lymphocytes are a combination of T helper (Th)1 and Th subtypes, and neutrophils and monocytes are more prominent in the lesions of chronic urticaria than in the late-phase ... Progress and Challenges in theUnderstandingof Chronic Urticaria ionomycin and found that CD4+ lymphocytes from patients with chronic urticaria produced significantly higher amounts of IL-4 and IFN-c...
... enhanced the expression ofmultiple MMP mRNAs (namely, MMP-1, -2, -3, -7, -10, and 11; p < 0.05) As in the case of MMP protein expression pattern, the response ofthe fibroblasts in terms of MMP ... in less severe SA and osteomyelitis in murine models of these diseases We therefore tested the ability of cell lysates and culture supernatants obtained from these mutants and their isogenic parent ... to augment the risk of infection in patients with RA The reasons for the predominance of S aureus in SA andthe mechanisms of pathogenecity are not yet fully understood The synovium of patients...
... systematic understandingofthe impact ofthe condition on individuals is currently hampered by the lack of an organized understandingof what aspects of a person’s life is affected, and second, ... process, the end point of this paper is the detailing ofthe hypothesized measurement model ofthe overall burden of back pain from the perspective of individuals with this condition andthe description ... the top right hand corner; 2) the variety of statements related to the effort of living, down the right hand side ofthe map These range from having to think about and plan daily activities and...
... disorder Like the pervasive effects of culture, distortion of consciousness lies at the heart of both the individual experience of mental disorder andthe effect of it on the embedding ofthe individual ... or the other ofthe teams, or separate counts ofthe number of bounce and areal passes During the game, a figure in a full gorilla suit appears, faces the camera, beats its breast, and walks off ... [11] Invoking the spirit ofthe Shannon-McMillan Theorem, essentially the zero-error limit ofthe Rate Distortion Theorem discussed in the Mathematical Appendix, allows definition of an adiabatically,...
... dissertation of Fraser (2009) and Beyza and Leyla (2007), andthe examination on brand equity of Nguyen & Nguyen (2008) Within the scope ofthe first chapter, the retail market of Vietnam in general and ... as umbrella brand (B-level brand of price and A-level brand of quality) of food products only They are therefore set to compete to corresponding levels of national brands The brand level is ordered ... supported by the data On the other hand, variety attributes ofthe store had no effect on the consumer attitudes towards private labels and hypothesis H1 was thus rejected Hypotheses and their status...
... school towardsthe application of pair and groupwork in teaching and learning speaking skills (ii) to examine the current situations ofthe application of pair and group work in teaching and learning ... with their working partner rather than the neighbor These depend on the amount of time as well as the type of activity In groupwork, the teacher divides the class into small groups to work together ... frequency ofthe organizing pair and group work, 75 % ofthe teachers said that they often organized pair work and group work in their speaking lessons and 25 % organized always Question stated the...