tool condition monitoring tcm for ball nose milling

Use of upconversion fluorescent nanoparticles for simultaneous imaging, detection and delivery of sirna

Ngày tải lên : 14/09/2015, 08:39

... Processing for Properties and Performance 11-15 Dec 2006, Singapore Proceeding 46-48 Oral Presentation Shan Jiang, Wee Beng Tan and Yong Zhang Multifunctional Nanoparticles-mediated siRNA Delivery for ... receptors and cytoskeleton for a high sensitivity of detection with strong signal-to-background ratio for imaging of cells In addition, the nanoparticles were also used for targeted delivery of ... Yezhelyev et al., 2007) For example, Yezhelyev et al demonstrated the use of multicolor QDs for quantitative and simultaneous profiling of multiple biomarkers using FFPE (formalin-fixed and paraffin...

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In vitro and in vivo evaluation of transferrin conjugated lipid shell and polymer core nanoparticles for targeted delivery of docetaxel

Ngày tải lên : 09/10/2015, 11:18

... formulated in PLGA/50-50 NPs formulation, PLGA/50-50 Tf NPs formulation and Taxotere® at various drug concentrations Table 4: Mean non-compartmental pharmacokinetic parameters of SD 78 rats for ... rationale for using nanocarrier to reformulate the docetaxel without using Tween 80 Docetaxel formulation without using potentially toxic adjuvant, Tween 80 (polysorbate 80), can be achieved by formulation ... count for SD rats after intravenous 79 administration of Taxotere® and PLGA/50-50 NPs at a dose of 7.5 mg/kg, and for rats receiving no injection (as control) Table 6: Serum chemistry for SD...

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báo cáo khoa học: " Conjugated polymer nanoparticles for effective siRNA delivery to tobacco BY-2 protoplasts" potx

Ngày tải lên : 11/08/2014, 11:21

... FM4-64 for 10 min, showed uniform red fluorescence in the plasma membrane, and bright spots where vesicles begin to form (Figure 2A, arrowheads) Few internal vesicles appear Following staining for ... (bp) using forward (5’- AGTGTATGTGGGTACCGGATG- 3’) and reverse (5’- CCATATGGGACA ATGCCTAC - 3’) primers Following a 5-min denaturation at 94° C, PCR was performed for 34 cycles of 94°C for min, ... internal control Following 10-min denaturation at 95°C, PCR was performed for 30, 35, 40, 45 cycles of 95°C for 15 s and 60°C for 60 s PCR products were analyzed using ethidium bromide stained...

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Báo cáo hóa học: " Both FA- and mPEG-conjugated chitosan nanoparticles for targeted cellular uptake and enhanced tumor tissue distribution" docx

Ngày tải lên : 20/06/2014, 22:20

... the resultant mixture, followed by stirring for 12 h at 37°C to form chemical cross-linking NPs, which were isolated by centrifugation at 12,000 rpm for 30 min; and the deposits (NPs) were then ... stirred at room temperature under dark condition for h, and a yellow FA-NPs suspension was obtained The FA-NPs were collected by centrifugation at 12,000 rpm for 30 min, and the deposit was washed ... chitosan microspheres as drug carrier for prednisolone sodium phosphate as model for antiinflammatory drugs J Control Release 1996, 39:17 Tian XX, Groves MJ: Formulation and biological activity...

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báo cáo hóa học: " Beyond platinum: synthesis, characterization, and in vitro toxicity of Cu(II)-releasing polymer nanoparticles for potential use as a drug delivery vector" ppt

Ngày tải lên : 21/06/2014, 02:20

... Only peaks for C, O, and Cu were observed in EDX spectra obtained for CuCNPs (Figure 2B), and the measured weight percents were consistent with both ICP MS and XPS EDX was also performed on samples ... MS and XPS EDX was also performed on samples immediately before and after the addition of CuSO Before CuSO4 treatment, only peaks for C, O, and Na were observed; after treatment, the Na peak ... nitric acid and then analyzed for6 3Cu content via ICP MS Cu content was determined by comparison with a calibration Microanalysis was performed by Columbia Analytics (formerly Desert Analytics)...

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Báo cáo hóa học: " Oral Delivery of DMAB-Modified DocetaxelLoaded PLGA-TPGS Nanoparticles for Cancer Chemotherapy" potx

Ngày tải lên : 21/06/2014, 08:20

... sonicated for 120 s at 25 W output to form O/W emulsion The emulsion was then evaporated overnight under reduced pressure to remove DCM The particle suspension was centrifuged at 22,000 rpm for 20 ... DMAB-modified PLGA-TPGS nanoparticle suspension at 37°C for h, the cells were rinsed with cold PBS for three times and then fixed by ethanol for 20 The cells were further washed twice with PBS, ... amount of nanoparticles for 24, 48 and 72 h, respectively At determined time, the formulations were replaced with DMEM containing MTT (5 mg/ml) and cells were then incubated for additional h MTT...

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Báo cáo hóa học: " Fluorescence Modiﬁed Chitosan-Coated Magnetic Nanoparticles for High-Efﬁcient Cellular Imaging" pdf

Ngày tải lên : 22/06/2014, 01:20

... was still sufficient emission for biological imaging The strong and stable fluorescence of the FITC-CS@MNPs provided a visual detection method for cell labeling and monitoring their location in ... resonance contrast agents for MRI and optical probes for intravital fluorescence microscopy Cytotoxicity test demonstrated that the prepared FITC-CS@MNPs possessed a suitable property for biomedical application ... parameter for their metabolic activity Figure 11 demonstrates a dose-dependent reduction in MTT absorbance for cells treated with FITC-CS@MNPs and naked MNPs After having been incubated for 12 h,...

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Magnetic chitosan nanoparticles for removal of Cr(VI) from aqueous solution

Ngày tải lên : 02/07/2014, 14:14

... the form of H2CrO4, while in the pH range of 1–6, different forms of chromium 2− − 2− − such as Cr2O7 , HCrO4 , and Cr3O10 coexist while HCrO4 predominates 2− 2− As the pH increases, those form ... nanoparticles Therefore, maintaining such a high saturation magnetization value (Ms) after coating these nanoparticles is advantageous and susceptible to the external magnetic ﬁeld for magnetic separation ... respectively), when keeping reactive amino groups intact for complexing reaction with heavy metal ions [14,16,19] Next, selecting an optimum pH is very important for the adsorption process, since pH affects...

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báo cáo khoa học: "Cationic nanoparticles for delivery of amphotericin B: preparation, characterization and activity in vitro" potx

Ngày tải lên : 11/08/2014, 00:22

... integrity of red blood cells [28] Therefore, similar studies should be performed for the formulations described in this paper Conclusion At the chosen condition for the AmB/DODAB BF/CMC assembly, ... allowed to interact for 10 minutes Thereafter, CMC was added and allowed to interact for 20 minutes before adding PDDA, which was also allowed to interact for 20 minutes, before determining zeta-average ... Correlation for AmB formulation at low (ᮀ) and high P (l) Correlation between Candida albicans viability (%) and zeta-potential (mV) for AmB formulation at low (ᮀ) and high P (●) At high P, formulations...

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ROMP based polymer nanoparticles for the targeted delivery of antitumor agents

Ngày tải lên : 23/08/2015, 18:48

... OH 100% exo Institute for BioNanotechnology in Medicine A Toolbox for Monomer Development I O O O OH Cl n O OH O Br O >120 new monomers for ROMP Watson et al Institute for BioNanotechnology in ... Institute for BioNanotechnology in Medicine Requirements for Drug Delivery • Drug delivery particle should self-assemble from drug molecules, components for targeting, and components for stability ... O’Halloran group Institute for BioNanotechnology in Medicine Summary • ROMP - powerful methodology for the construction of a multifunctional polymeric nanoparticle platform for molecular therapeutics...

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Delivery of proapoptotic biomolecules and drugs using amphiphilic block copolymer nanoparticles for anti cancer therapy

Ngày tải lên : 30/09/2015, 05:59

... treated with different formulations for 48 hours P(MDS-co-CES) concentrations were fixed at 40 ppm for both cell lines Cell culture was performed in serum-containing medium Each condition was tested ... required for protein functions For many proteins, it can be difficult to manufacture in recombinant form or expressed in microbial systems For instance, the commonly used bacterial systems for protein ... Methods for analyzing drug interactions 1.2.5 Issues and strategies for combination therapy 1.2.5.1 Practical issues for consideration 1.2.5.2 Mechanistic considerations 1.2.5.3 Strategies for determining...

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Carboxymethyl chitosan functionalized magnetic nanoparticles for disruption of biofilms of straphylococcus aureus and escherichia coli

Ngày tải lên : 02/10/2015, 17:14

... incubation in PBS for 24 h, (b) and (e) with addition of CMCS-MNPs (2.0 mg/mL) without MF for and after incubation in PBS for 24 h, (c) and (f) with addition of CMCS-MNPs (2.0 mg/mL) with MF for and after ... CMCS-MNPs (2.0 mg/mL) without a MF for and after incubation in PBS for 24 h, (c) and (f) with addition of CMCS-MNPs (2.0 mg/mL) with MF for and after incubation in PBS for 24 h Figure 4-10 Viability ... rate can be expected Therefore, efforts have focused on the development of bacterial-resistant prosthetic parts through binding of antimicrobial polymers to the materials For instance, chitosan...

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Tài liệu KRONE - Catalogue - HighBand - For Broadband delivery - HK- Jun 2000 pdf

Ngày tải lên : 09/12/2013, 15:15

... termination tool KRONE termination tool Backmount frame mounting system I P O RTA N T N O T E M KRONE termination tool HIGHBAND and Series modules can both be terminated using the standard KRONE tool ... Test Cord Used for testing HIGHBAND 10 circuits Product Number: 6451 100-30 3M Pack Qty: Bag of Please contact KRONE for further information on the full range of Test/Patch cords for the HIGHBAND ... contact maintain a continual force on the connection Clamping ribs isolate contact area from stress on both sides of the connection Grips wire from two directions for greater security Resists...

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Tài liệu KRONE AccessNET - Opens the Pipe for Broadband Delivery doc

Ngày tải lên : 22/12/2013, 12:15

... • Internet Access or combinations of these and other services, the ‘Speed for Need’ is critical To satisfy this need for speed the delivery infrastructure has to be resilient, cost effective ... SUBSCRIBER INTERFACE SOLUTIONS Products for both residential and commercial subscribers that solve issues around Network Termination Points, receiving and managing information via POTS, ISDN, xDSL, etc ... AccessNET as an end to end connectivity solution for access networks provides seamless integration to PremisNET; the complete in-house solution for structured cabling in commercial premises Central...

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Báo cáo khoa học: NovelN,N¢-diacyl-1,3-diaminopropyl-2-carbamoyl bivalent cationic lipids for gene delivery – synthesis,in vitro transfection activity, and physicochemical characterization docx

Ngày tải lên : 23/03/2014, 07:20

... cytofectins for gene delivery H3C H3C N CH3 N H3C N O O O NH O NH R R The R group varies with the derivative: C11H23 for dilauroyl (1,3lb1) C13H27 for dimyristoyl (1,3lb2) C15H31 for dipalmitoyl ... parameter is equal to for a univalent base (and -1 for a monoprotic acid) The pKa values listed in Table for the bivalent lipids are the mean of two acid dissociation constants, one for each of the ... except for formulations containing 1,3lb1, which were poorly tolerated (data not shown) FEBS Journal 275 (2008) 148162 ê 2007 The Authors Journal compilation ê 2007 FEBS 151 Novel cytofectins for...

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nanoparticle technology for drug delivery, 2006, p.427

Ngày tải lên : 04/06/2014, 15:15

... requirements for nanoparticulate systems can vary These aspects are discussed in Chapter for injectable delivery, Chapter for oral delivery, Chapter 10 for brain delivery, Chapter 11 for ocular ... Supercritical Solution for Particle Formation 59 RESS with Solid Cosolvent for Nanoparticle Formation 63 Supercritical Antisolvent Process for Particle Formation 66 SAS with Enhanced ... reduction operations utilize high-shear wet milling for the production of nanoparticles Milling is explained in detail in chapter Typical operation time for the wet milling may be hours to days, hence...

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Báo cáo hóa học: " Efficient data replication for the delivery of highquality video content over P2P VoD advertising networks" pdf

Ngày tải lên : 20/06/2014, 22:20

... influences the availability of resources in a P2P network; therefore, it is essential for system designers to determine an appropriate policy for sharing resources to deal with video distortion resulting ... title and video description fields may provide useful information about the selfinterest of individual peers, making them a useful tool for the promotion of advertisements Second, advertising ... quality varies greatly There exists at least one forward path and a backward path for each peer in the channel The RTT is, by definition, the sum of the forward trip k times (FTT) and backward trip...

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Báo cáo hóa học: " Functionalized halloysite nanotube-based carrier for intracellular delivery of antisense oligonucleotides" pdf

Ngày tải lên : 20/06/2014, 23:20

... laser for FAM excitation at 488 nm was used for imaging, and an oil immersion objective (Plan Apo, SEIWA OPTICAL AMERICA INC., Santa Clara, CA, USA; magnification = 63 × 1.4) was used for cellular ... drug delivery, bioimplants, and for protective coating (e.g., anticorrosion or antimolding) [19-23] Despite these prospects, however, their utilization as biocarrier for ASODNs delivery has been ... clay powder was added, and the suspension was dispersed ultrasonically for 30 The suspension was then refluxed at 120°C for 20 h under constant stirring In the refluxing system, a calcium chloride...

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Báo cáo hóa học: " Catalytic properties of Co3O4 nanoparticles for rechargeable Li/air battery" doc

Ngày tải lên : 20/06/2014, 23:20

... catalyst for the air electrode of a Li/air battery The shape and size of the nanoparticles are observed using scanning electron microscopy and transmission electron microscopy analyses The formation ... villiform-type Co3O4 nanoparticles is superior to that of electrodes containing cube- and flower-type Co3O4 nanoparticles This is probably due to the sufficient pore spaces of the villiform-type ... batteries are potential candidates for advanced energy storage systems because of their high storage capability [1-3] They not store a ‘cathode’ in the system, which allows for a higher energy density...

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Báo cáo hóa học: "Preparation and evaluation of novel mixed micelles as nanocarriers for intravenous delivery of propofol" potx

Ngày tải lên : 21/06/2014, 04:20

... CLE before the first 12 h, the release rate of the two formulations was comparable thereafter Overall, quick release rate for mixed micelles might produce a favorable pharmacological effect for ... of the EE was performed using the same method described above Page of Stability of mixed micelles under storage condition The physical stability of mixed micelles under storage conditions was also ... micelles and CLE, separation of the two phases was performed using ultracentrifugation Ultracentrifugation was performed at 10,000 rpm (14000 g) for 20 Amicon ultra centrifugal filter units (Amicon...

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