tissue derived stem cells and their regeneration potential

... Cite this article as: Pak: Regeneration of human bones in hip osteonecrosis and human cartilage in knee osteoarthritis with autologous adipose -tissue- derived stem cells: a case series Journal ... the true mechanism of tissue regeneration Conclusions After three months of treatment, all the patients reported on above were able to straighten their hips and extend their knees further, affecting ... the staff of Miplant Stems Clinic Authors’ contributions JP was in charge of patient treatment and follow-up, was responsible for manuscript drafting and revision, and read and approved the final...

Ngày tải lên: 10/08/2014, 23:21

... thigh region, and used lentiviruses to induce the cells to pluripotent cells These pluripotent cells are studied and characterized The pluripotent stem cells exhibited morphology and genomic markers ... Aims and objectives 14 Literature Review 15 3.1 Human Embryonic Stem Cells (hESCs) 15 3.2 Porcine Embryonic Stem Cells 16 3.3 Generation of Induced Pluripotent Stem Cells ... to Induced Pluripotent Stem Cells 45 iv 4.10 Culture of Porcine Induced Pluripotent Stem Cells 45 4.10 Characterization of Porcine Induced Pluripotent Stem Cells 46 4.10.1 Immunocytochemical...

Ngày tải lên: 30/09/2015, 10:13

... 1155-1160 27 Ogawa R The importance of adipose -derived stem cells and vascularized tissue regeneration in the field of tissue transplantation Curr Stem Cell Res Ther 2006, 1, 13-20 28 Olby NJ, De Risio ... HE Stem cell therapy for neurologic disorders: therapeutic potential of adipose -derived stem cells Curr Drug Targets 2005, 6, 57-62 33 Satake K, Lou J, Lenke LG Migration of mesenchymal stem cells ... adipose tissue- derived stromal cells after cerebral ischemia in rats Exp Neurol 2003, 183, 355-366 Kang SK, Shin MJ, Jung JS, Kim YG, Kim CH Autologous adipose tissue- derived stromal cells for...

Ngày tải lên: 07/08/2014, 23:22

... engineering and regeneration [134] Mesenchymal stem cells versus embryonic stem cells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can ... remaining stem cells for tissue regeneration and repair? In conclusion, MSCs derived from adult tissue present an exciting progenitor cell source for applications of tissue engineering and regenerative ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymal stem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stem cells are found...

Ngày tải lên: 09/08/2014, 01:21

... pad cells IPFP cells at passage expanded with and without FGF-2 stained strongly for CD13, CD44, CD90, and CD105 (markers for mesenchymal stem cells) and for CD29 (β1 integrin) (Figure 3) The cells ... was derived from haematopoetic, neural, or myogenic progenitors or stem cells Evidence for pericytes in the IPFP tissue and IPFPderived cells 3G5 distinctively stains pericytes and these cells ... from IPFP -derived cells contained cells that can be grown as clones after limiting dilution and that some clonally expanded cells had high proliferative potential The lack of CD34 and CD56 expression...

Ngày tải lên: 09/08/2014, 10:23

... embryonic stem cells, induced pluripotent stem cells and then the adult bone marrow derived stem cells, which are well known and best studied for their immune modulatory properties Finally, cells ... Fetal/neonatal stem cells 2.4.1 Background Fetal and neonatal stem cells come in between embryonic and adult stem cells in the developmental continuum Studies of these cells have provided information and ... mesenchymal stem cells Adult stem cells, also known as somatic stem cells, are found throughout body after embryonic development, in various tissues and organs They are undifferentiated cells that...

Ngày tải lên: 11/09/2015, 10:02

... shed light on the role of neural stem cells as the transformational cells in GBM formation, hence their accurate terminology as glioma stem cells or -initiating cells1 4, 16, 17 Traditionally, the ... patient‟s original tumor 1.3 GLIOMA STEM CELLS OR -PROPAGATING CELLS In recent years, the distinction between glioma stem cells, gliomainitiating or –propagating cells has been highlighted Elegant ... Self-Renewal and Multipotentiality 3.1.1 Patient magnetic resonance imaging (MRI) and 31 histopathology 3.1.2 Anaplastic oligoastrocytoma -derived GPCs (NNI-8) display 33 stemness expression and extensive...

Ngày tải lên: 03/10/2015, 21:57

... Stem cells circulate among tissues, and stem cells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process in which a lot of molecules were involved Once tissues ... molecules, and stem cells are motivated and migrate into peripheral blood and target tissue, in which specific receptors or http://www.medsci.org Int J Med Sci 2011, ligands expressed in injured tissues ... Chen B, et al Ex vivo expansion and in vivo infusion of bone marrow -derived Flk-1+CD31-CD34- mesenchymal stem cells: feasibility and safety from monkey to human Stem Cells Dev,2006,15(3):349-357...

Ngày tải lên: 25/10/2012, 11:18

... structure of posttranslational modifications of plasma -derived and recombinant human HCII from CHO cells and their effects on heparin binding MATERIALS AND METHODS Outdated citrated human plasma was ... delayed-extraction and reflectron systems and a N2 laser (337 nm) operating with 3-ns pulse width and 107)108 WÆcm)2 irradiance at the surface of 0.2 mm2 spots In addition to the positive mode standard procedure ... posttranslational modifications of human HCII from circulating blood and genetically modified CHO cells and their effects on heparin binding All three potential N-glycosylation sites were found to be populated...

Ngày tải lên: 08/03/2014, 22:20

... cells derived from cultured mouse ESCs are fat cells, various brain and nervous system cells, insulin-producing cells of the pancreas, bone cells, hematopoietic cells, yolk sac, endothelial cells, ... http://books.nap.edu/catalog/.html STEM CELLS AND THE FUTURE OF REGENERATIVE MEDICINE ment cells of the skin, cartilage and bone in the face and skull, and connective tissue in many parts of the body Neural crest cells from ... with fetal tissue so far has been limited to only a few cell types: neural stem cells, including neural crest cells; hematopoietic stem cells; and pancreatic islet progenitors Neural stem cells, ...

Ngày tải lên: 15/03/2014, 09:20

... astroglial cells and the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts derived ... history and the most advanced discoveries in neural stem cells This book provides the strategies and challenges of utilizing neural stem cells for therapy of neurological disorders and brain and ... Formation of Nervous Systems and Neural Stem Cells in Ascidians 121 Kiyoshi Terakado Chapter Regeneration of Brain and Dopaminergic Neurons Utilizing Pluripotent Stem Cells: Lessons from Planarians...

Ngày tải lên: 30/03/2014, 23:20

... novel circulating human embryonic blood stem cells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stem cells into embryoid bodies comprising the ... tái tạo Tài liệu tham khảo Amit et al (2000); Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture Dev Biol 227, ... Thomson, J A., et al (1998); Embryonic stem cells lines derived from human blastocysts Science 282, 1145 - 1147 12 Raisman, G., (2001); Olfactory ensheathing cells - another miracle cure for spinal...

Ngày tải lên: 02/04/2014, 22:20

... at 28 and 112 J/cm2 of human peripheral blood mononuclear cells, a heterogeneous population of T cells, B cells, NK cells, and monocytes has been described to induce chromatin relaxation and to ... [115] Direct evidence of LLL stimulating stem cells has been obtained using mesenchymal stem cells derived both from the bone marrow and from the adipose tissue [116,117] Interestingly in vivo ... N, O’Valle F, Hernandez-Cortes P, Rico L, Buscher D, Delgado M: Human adipose -derived mesenchymal stem cells reduce inflammatory and T cell responses and induce regulatory T cells in vitro in...

Ngày tải lên: 18/06/2014, 16:20

... 1998 origin primary tissue primary tissue pleural effusion primary tissue primary tissue primary tissue primary tissue primary tissue primary tissue primary tissue primary tissue pleural effusion ... breast tissue normal mammoplasty (transformed) normal mammoplasty (transformed) primary tissue primary tissue primary tissue primary tissue primary tissue lymph node primary tissue primary tissue ... Telmer and Eva Turley Breast Cancer Stem Cells 235 Chapter 11 The Microenvironment of Breast Cancer Stem Cells Deepak Kanojia and Hexin Chen Chapter 12 Involvement of Mesenchymal Stem Cells in...

Ngày tải lên: 27/06/2014, 17:20

... adult cells are already specialized, their potential to regenerate damaged tissue is limited Another limitation of adult stem cells is their inability to effectively grow in Human embryonic stem cells ... Andrews PW Culture and characterization of human embryonic stem cells Stem Cells Dev 2004, 13, 325-336 18 Drukker M, Benvenisty N The immunogenicity of human embryonic stem -derived cells Trends Biotechnol ... repair and transplantation medicine There are several approaches in human clinical trails that employ adult stem cells (such as blood-forming hematopoietic stem cells and cartilage-forming cells) ...

Ngày tải lên: 07/08/2014, 18:21

... Feinberg AP: Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts Nat Genet 2009, 41:1350-1353 ... embryonic stem cells and differentiation Nat Rev Mol Cell Biol 2006, 7:540-546 51 Park SH, Kook MC, Kim EY, Park S, Lim JH: Ultrastructure of human embryonic stem cells and spontaneous and retinoic ... Pellegrini M, Plath K, Lowry WE: Molecular analyses of human induced pluripotent stem cells and embryonic stem cells Cell Stem Cell 2010, 7:263-269 94 Deng J, Shoemaker R, Xie B, Gore A, LeProust EM,...

Ngày tải lên: 11/08/2014, 12:21

... their capacity for tissue regeneration by homing at the injured tissue and differentiating onto damaged cell phenotypes, MSC secrete soluble mediators which can immuno-modulate inflammation and ... would be sensed by the MSC in the bone marrow (and in other tissues which are also reservoirs of these cells) and would induce their mobilization from their original niche to the bloodstream In fact, ... single-cell -derived colonies than human marrow stromal cells Stem Cells 2001, 19:219-25 10 Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, et al.: Clinical applications of blood -derived and marrow-derived...

Ngày tải lên: 12/08/2014, 11:22

... augment resident stem cells, and we comprehensively review such data from lung Finally, there is great hope that embryonic stem cells, embryonic germ cells, or even adult somatic stem cells can be ... mast cells, and macrophages, has hindered identification of lung stem cells and patterns of cell migration during tissue renewal Nevertheless, the prevailing view is that airway basal and Clara cells ... stem cells may home to the lung There is great excitement and hope that exogenous and/ or mobilized endogenous stem cells may be harnessed to prevent or treat acute and chronic lung diseases and...

Ngày tải lên: 12/08/2014, 18:21