therapeutic applications of nuclear medicine

... sources in nuclear medicine is to avoid or minimize the chance of contamination For safe use of radionuclides in nuclear medicine, the following basic requirements should be met: The nuclear medicine ... generated due to nuclear medicine investigations hardly poses any problem of storage or disposal However, it is not the same for therapeutic nuclear medicine, for which a large amount of radioactive ... Piffanelli A (1999) Quality control of Mo99/Tc99m generators: results of a survey of the radiopharmacy working group of the Italian Association of Nuclear Medicine (AIMN) Nucl Med Com mun 20:1077...

Ngày tải lên: 06/03/2014, 09:21

... from the presence of Dr L Biro, Minister Secretary of State with Nuclear Safety, who presented a documented image of the nuclear energy in Romania and emphasized the importance of a durable development ... 3,4He) emitted in neutron of interest [5] for evaluation of nuclear data for D on 6'7Li The basic input for the calculations of the double-folded OP are the nuclear densities of the colliding nuclei ... NEW APPLICATIONS OF MLJCl—S^FP F=ISSIOiNI This page is intentionally left blank Proceedings of the International Workshop on the NEW APPLICATIONS Bucharest, Romania OF - September...

Ngày tải lên: 17/03/2014, 20:21

... History of Nuclear Medicine Henry N Wagner, Jr A Personal History of Nuclear Medicine Henry N Wagner, Jr., MD, PhD Professor of Environmental Health Sciences, Johns Hopkins Bloomberg School of Public ... focus of research in the future of the NIH This declaration of intent by the NIH was exciting for those in nuclear medicine, because molecular imaging had been the hallmark of nuclear medicine ... History of Nuclear Medicine Figure Elias Zerhouni trained in nuclear medicine at Johns Hopkins At present, he is head of the National Institutes of Health in Bethesda, Maryland “atomic medicine ...

Ngày tải lên: 29/03/2014, 15:20

... number of nucleotides to the 3’ side of the cleavage site of the substrates and by changing the length of the 5’ hybridizing arms of the nbozymes All Hendry, Lockett, and McCall Length of Helix ... range of helix nbozyme-substrate lengths were assayed m order to optimize the length of helix By making a ribozyme capable of forming a range of lengths of helix up to 10 bp, the range of hehx ... linkers consisting of nucleotides (20,25,26), or of short polymers of ethyleneglycol and phosphopropanedlol (17,19) The rates of cleavage by mimzymes increase as the number of atoms m the chain...

Ngày tải lên: 11/04/2014, 10:37

... rate of approximately 0.1%, where an amount of Liras Journal of Translational Medicine 2010, 8:131 http://www.translational -medicine. com/content/8/1/131 fat ranging from a few hundreds of milliliters ... characteristics of the different therapeutic protocols and on the requirements of each condition, each type of stem cell has its advantages and disadvantages Thus, embryonic stem cells have the advantages of ... in implantation of hepatic stem cells, or in implantation of hepatic cells obtained by differentiation of a different type of stem cell, such as mesenchymal stem cells Other applications, still...

Ngày tải lên: 18/06/2014, 16:20

... an altered level of miRNA production is a defining trait of tumorigenesis [16,17] While the production of some miRNAs is universally altered in tumors, more often unique patterns of miRNA production ... miRNAs of about 22 nucleotides originate from primary miRNA (pri-miRNA) transcripts Nuclear pri-miRNAs of hundreds to thousands of base pairs are converted into stem–loop precursors (pre-miRNA), of ... risk stratification Applications in cancer for microRNAs and prediction of therapeutic responses in patients with cancer Corruption of miRNA expression in cancer The genetic basis of cancer, in part,...

Ngày tải lên: 16/03/2014, 01:20

... paragraph of section 2.1 45 NUCLEAR MEDICINE NUCLEAR MEDICINE 3.1 Introduction The safe, efficient and efficacious practice of nuclear medicine involves the integration of a number of processes ... open to a wide range of applications They may offer a multiplicity of modes (and sub-modes) of operation A set of the modes and submodes that represent the intended uses of the equipment should ... verification Limitation of overexposure Verification of AEC optical density (OD) under reference conditions Repeatability of OD Verification of sensors of AEC Verification of AEC IEC (1994) EN (1994)...

Ngày tải lên: 17/03/2014, 14:20

... to the leg lengths of each subject, so that the hip and knee joints of the Lokomat were aligned with those of the subject During 22 Applications of EMG in Clinical and Sports Medicine both Lokomat ... choice of the cut-off frequency of an ideal lowpass filter for pre-filtering purposes therefore is 500 Hz, resulting in a typical Sampling Frequency of 1000 Hz, twice the cut-off frequency of pre-filtering ... equations (31) and (28) in terms of Mi and yi resulted in the determination of the weights of the cubic spline ai, bi, ci and di 30 Applications of EMG in Clinical and Sports Medicine =6 =2 = +2 (31)...

Ngày tải lên: 27/06/2014, 16:20

... that often arises is that of the communication of the results of computer simulation experiment to other members of a community Quite often the necessary description of the technical substance of ... manageable set of applications, the main thrust of this book is to emphasize applications of Monte Carlo simulation methods in biology and medicine But it became necessary, due to the acceptance of a large ... is an eclectic mix of applications of Monte Carlo methods in many fields of research should not be surprising, because of the ubiquitous use of these methods in many fields of human endeavor In...

Ngày tải lên: 29/06/2014, 13:20

... strategies, a number of generic problems must be overcome for the development of successful clinical applications These include development of methods for reliably generating large numbers of specific ... whether transdifferentiation of MSCs or other stem cell populations occurs at a high enough frequency to be useful for stem cell replacement therapy Regardless of the source of the stem cells used ... study of human ES cells has been controversial, and their use in clinical applications would be unacceptable to some patients and physicians despite their enormous potential Somatic cell nuclear...

Ngày tải lên: 07/07/2014, 01:20

... ischemic heart disease; and (3) stimulation of endogenous stem cells to facilitate repair—e.g., administration of appropriate growth factors to amplify numbers of endogenous stem/progenitor cells or ... Disease and Cardiomyocyte Regeneration Because of the high prevalence of ischemic heart disease, extensive efforts have been devoted to cell replacement of cardiomyocytes Historically, the adult heart ... infarct size The preponderance of evidence suggests that the functional benefits are not derived from direct generation of cardiomyocytes but rather from indirect effects of the stem cells on resident...

Ngày tải lên: 07/07/2014, 01:20

... the development of dyskinesia Transplantation of stem cell– derived dopamine-producing cells offers a number of potential advantages over fetal transplants, including the ability of stem cells ... reported, and clinical trials of such cells have begun for a number of neurologic disorders Clinical trials of a conditionally immortalized human cell line and of human umbilical cord blood cells ... level The proliferative capacity of the replacement cells must be tightly regulated to avoid excessive expansion of βcell numbers with the consequent development of hyperinsulinemia/hypoglycemia,...

Ngày tải lên: 07/07/2014, 01:20

... members of a society Stem cell research raises questions about the definition of human life, and it has raised deep fears about our ability to balance issues of justice and safety with the needs of ... Essentials of Stem Cell Biology San Diego, Elsevier Academic Press, 2006 Mimeault M et al: Stem cells: A revolution in therapeutics-recent advances in stem cell biology and their therapeutic applications ... coadministration of scaffolding, artificial extracellular matrix, and/or growth factors to orchestrate differentiation of stem cells and their organization into appropriate constituents of the organ...

Ngày tải lên: 07/07/2014, 01:20

... clinical applications Here, we refined and compared three of the state -of- the-art immune effector cell preparation approaches, the IFN-γ and the CD137 selection methods for emergency preparation of therapeutic ... sample, 5,000 Page of 16 (page number not for citation purposes) Journal of Hematology & Oncology 2009, 2:34 microbeads were acquired, facilitating the calculation of absolute numbers of target cells ... increased proportion of CD137 positive CD4 cells in the total population of T cells before and after stimulation (Fig 1B) However, quantitative analysis of the expression level of CD137 demonstrated...

Ngày tải lên: 10/08/2014, 22:20

... multiplexing capabilities of protein probes The group of Prof Mirkin has designed a sophisticated multifunctional Page of (page number not for citation purposes) Journal of Nanobiotechnology 2004, ... AP: Biological applications of colloidal nanocrystals Nanotechnology 2003, 14:R15-R27 Pankhurst QA, Connolly J, Jones SK, Dobson J: Applications of magnetic nanoparticles in biomedicine J Phys ... reproducibility of beads was high letting for the bead identification accuracies of 99.99% Manipulation of cells and biomolecules [30] Functionalised magnetic nanoparticles have found many applications...

Ngày tải lên: 11/08/2014, 00:22

... ward, neurological screening revealed loss of strength of both shoulders and arms and sensibility loss of both arms This was attributed to compression of the shoulders by the concrete blocks Eight ... effectiveness of artificial cooling will never be tested in a randomized clinical trial This means that case reports describing the use of therapeutic hypothermia and demonstrating therapeutic ... evidence of neurological impairment The situation of patient A is comparable with the clinical situation of stroke There was a localized ischaemic period resulting from the dissection of a cerebral...

Ngày tải lên: 12/08/2014, 20:20

Ngày tải lên: 31/07/2015, 20:17

... the understanding of collagen P4H’s structure, stereochemistry, and mechanism of action, a variety of small molecule inhibitors of collagen P4H were developed with the aim of treating fibrosis ... the delivery of PHIs is necessary We therefore propose the use of PHI-delivering scaffolds as a strategy for improving vascularization in tissue engineering applications As a proof -of- concept, ... regenerative medicine applications As discussed in the previous chapter, repeated injections of PHIs into sites of implantation or injury is not feasible due to the associated pain, distress and risks of...

Ngày tải lên: 09/09/2015, 11:11

... POTENTIAL APPLICATIONS OF CHITOSAN-BASED HYDROGELS IN REGENERATIVE MEDICINE RUSDIANTO BUDIRAHARJO (M Eng.), Chulalongkorn University A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY ... and efficacy of covalent immobilization of growth factor for expanding the potential applications of chitosan hydrogel in bone and wound healing They also highlight the benefits of using the ... cleared of the biofilms However, this treatment is only effective to preserve the tooth, not to regenerate it Moreover, replacement of the filler is often needed due to the limited life span of the...

Ngày tải lên: 10/09/2015, 09:23

... without financal worry in Singapore I TABLE OF CONTENTS ACKNOWLEDGEMENTS TABLE OF CONTENTS SUMMARY I II VIII LIST OF TABLES X LIST OF FIGURES XI LIST OF SYMBOLS XIII CHAPTER I INTRODUCTION 1.1 ... of Nogo-B and Systematic Dissection of the Am-Nogo-A 92 3.3.1 Bioinformatics analysis 93 3.3.2 CD and NMR characterization of N- and C-termini of Nogo-B 97 3.3.3 CD and NMR characterization of ... II alignment of human RTNs 169 Appendix III Publications 173 VII SUMMARY Nogo-A, the largest isoform of RTN4/Nogo, was originally identified as an inhibitor of neurite outgrowth of the central...

Ngày tải lên: 14/09/2015, 12:53