... (and that these are the equivalent time-lines forthe G1 phase, tG1); then a further 58, 56, 54 and 52 days would be required for actual division ofthe tubercle bacilli to occur Therefore, M.tb ... bases as metabolites, the time ts required for DNA duplication by the tubercle bacillus may be estimated Second, from thetheoretical model that the timeline forthe G1 phase ofthe M.tb cell cycle ... valid forthe purpose of reducing time-lines to the reading of TB cultures What may be affected is drug resistance profiling, since this requires measurement ofthe levels of TMK in the culture Therefore,...
... Structure ofthe subject CHAPTER 1THEORETICAL BASISOF DEVELOPING BUSINESSSTRATEGYOF ENTERPRISES 1.1 Businessstrategy and its role in enterprises 1.1.1 Definition 1.1.2 Roles ofbusinessstrategy ... strategy, theenterprise should consider a number of factors that affect the choice ofstrategy These factors include the strength ofthe industry and theenterprise Strategic objectives ofthe enterprise, ... STRATEGYOF ENTERPRISES 1.1 Businessstrategy and its role in enterprises 1.1.1 Definition There are many definitions on businessstrategy Approaching in any way, the nature ofthebusiness strategy...
... proposing on the situation of manufacturer for board of directors 2.3 Summarizing the results of operations ofthe company during the period 2007 – 2011 2.3.1 Summarizing the operations ofthe Company ... incomplete information is incorrect Therefore, implementation of results and the plan table is often a big difference On the other hand, the planning based almost exclusively on thebasisof subjective ... Functional control ofthe Company is made good Operation in the form of joint stock company, the company had a separate board under the control ofthe General Assembly of shareholders ofthe Company...
... scientific analysis of actual situation ofthe firm Providing the evaluations and solutions for developing businessofthe firm forthe period of 2010 to 2015 Limitation and methodology of research ... duration for preparing and completing the report, the subject only focused on the matter of business- level strategyfor ALPHANAM Paints The methodology practiced in the report is a combination of ... 1962: the determination ofthe basic long-term goals and objectives of an enterprise and the adoption of courses of action and the allocation of resources for carrying out these goals” Kenneth...
... thousandth of a watt (10 mW) The milliwatt is the unit of measure used for power in telecommunications circuits Rather than absolute measure of power, we often concerned with the comparison of one ... us the ratio of two power levels, that is it expresses the gain ofthe system But some time we want to express the exact output power of a system rather than the gain In that case, we compare the ... to 3400 Hz Bandwidth, of a signal is the width ofthe spectrum The bandwidth ofthe intelligent voice signal is 3100 Hz Telephone equipment allows the voice a bandwidth of 4000Hz, which includes...
... whereas the A-domain of module activates two molecules of l-serine (Fig 1A) Another striking feature of these NRPSs is related to the C-terminus ofthe synthetase VioG Although there is no need for ... results from conformational control ofthe enzyme on the side chain rotamer ofthe bound substrate For example, in AsnO, a trans conformer is selected forthe v1 torsion angle of bound l-asparagine, ... number of residues ofthe sequence used forthe alignment The query and target structures are aligned in three dimensions on thebasisof spatial closeness, minimizing rmsd, and maximizing the number...
... by the K103N mutation The electron density for Cc ofthe K103N mutant structures is well defined but the quality ofthe map does not allow assessment ofthe orientation ofthe amide plane There ... reduced by the stacking of Od1 in between the plane ofthe thiourea moiety and the Ca of G190 Hence, the undefined orientation ofthe N103 amide Od1 and Nd2 atoms may reflect the repulsive forces exerted ... However, in the cases of MSC194 and PNU142721 the position ofthe sulfur atom is such that the repulsive forces are less apparent In the MSC194 mutant complex the rotational freedom ofthe amide...
... second conformation ofthe side chain of Glu221, which also adopts two conformations but not correlated with the anomeric form ofthe bound mannose is shown in dark green site for subunit B The crystal ... arm in the monosaccharide binding site [34] The conformation ofthe GlcNAcb(1–2)Man entity occupying the )1 and M subsites of LOL roughly resembles the conformation seen in the NA2F complex of PAL ... consequence ofthe correlation of fitting parameters often observed for weak binding events Evidence for this stems from the reproducibility of this result as well as from the c-value used in the titration...
... either the N45D or the N64D mutation into Dm-dNK (lacking the 20 C-terminal residues) The resulting mutants were first tested in two plate assays, either forthe presence ofthe TK activity or their ... and then the strains were examined for growth, +, in the presence of different concentrations of thymidine in the medium In the last column, LD100 values are given (in lM) forthe growth of KY895 ... phosphorylation ofthe natural substrates ofthe double mutant with the single mutant, it seems that the mutation N45D in the double mutant counteracts the negative effect(s) ofthe N64D mutation For phosphorylation...
... decrease in the cofilin binding in the presence of actin suggesting that the actin–cofilin complex impedes the interaction of cofilin with the actin peptide The complex formation between the C-terminal ... that this was the case for both ADP and ATP–actin (not Fig Effect of pH on the interaction of actin with cofilin (A) Effect of pH on the interaction of RITC-actin with cofilin Binding of RITC-labeled ... respect to the rest ofthe monomer In this report we study the pH-dependence ofthe actin– cofilin interface and provide evidence for a pH-dependent movement of subdomain that may be involved in the...
... [15, Theorem 1.1], the cardinality ofthe set of i-dimensional (h, µ)-fillings equals the dimension ofthe degree-2i part of H ∗ (H(X, h)) Therefore, the degree-i generators of R/Jh give the 2ith ... function Then The number of leaves in the h-tree at Level n + equals n i=1 βi The collection of leaf labels at Level n + in the h-tree is exactly thebasisof monomials Bh (µ) of R/Jh given by Theorem ... distinct The proof of Theorem 3.3.5 relies on combinatorial facts about the two numbers in question, namely the cardinalities ofthe set of possible (h, µ)-fillings and the set of leaves of an h-tableau-tree...