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Báo cáo y học: "Maternal Outcomes According to Placental Position in Placental Previa"
Ngày tải lên :
25/10/2012, 10:56
... exam prior to delivery In addition to the location in the anterior portion or posterior portion of uterus, they were classified by sonographers blinded to the outcomes when sonographic exam according ... outcomes, the hemoglobin level of prior to surgery, day after surgery, and days after surgery, the amount of transfusion during surgery, estimated blood loss during operation, placental accreta, hysterectomy, ... according to the level of the placental coverage over internal os of cervix as complete, partial, marginal, low lying, and vasa previa [10] Most of last sonographic exams were done on the day of operation...
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Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
Ngày tải lên :
25/10/2012, 10:02
... tendency to hyperglycaemia that are the root of hospital acquired hyperglycaemia and in the long term lead to development of diabetes Although the incidence of hospital acquired hyperglycaemia ... There were no differences in age and sex distribution Patients in the hyperglycaemia group had a higher proportion of positive family history of diabetes and higher body mass indexes During the ... hyperglycaemia had a higher proportion of positive family history of diabetes and higher median body mass index which shows that usual risk factors for diabetes contribute to development of hyperglycaemia...
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Báo cáo y học: " Derivation and preliminary validation of an administrative claims-based algorithm for the effectiveness of medications for rheumatoid arthritis"
Ngày tải lên :
25/10/2012, 10:45
... For infliximab, must have received the number of infusions expected between the index and the outcome visit date to conform to a schedule of 0, 2, 6, and 14 weeks followed by every weeks thereafter ... substantial contributions to conception and design, and to the analysis and interpretation of the data TRM and GWC handled acquisition of data All authors contributed to the manuscript revision ... sensitivity and specificity, unlike PPV and NPV, should be less dependent on the prevalence in the population, and more reflective of the test itself, lessening the impact of any unique features of the...
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Tài liệu Báo cáo khoa học: X-ray crystallographic and NMR studies of pantothenate synthetase provide insights into the mechanism of homotropic inhibition by pantoate docx
Ngày tải lên :
16/02/2014, 09:20
... back to the position of the Fig Superimposition of the A-chain of nPS (green), the B-chain of nPS (cyan), and the substrate-free protein (1IHO.pdb; magenta) The carbon and oxygen atoms of pantoate ... oxygen atoms of pantoate are shown in yellow and red, respectively The carbon and oxygen atoms of ATP are shown in red, the nitrogen atoms in blue, and the phosphorus atoms in orange (see text ... oxygen of Ser54 are hydrogen-bonded to the O4 atom of pantoate via a network that consists of two water molecules The backbone carbonyl oxygen of Phe56 is also hydrogenbonded to the O4 atom of...
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Tài liệu Báo cáo Y học: The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168 pdf
Ngày tải lên :
21/02/2014, 01:21
... in the conversion of GDP-4-keto-6-deoxy-D-mannose to GDP-4-keto-6-Ldeoxygalactose to GDP-L-fucose in the formation of fucose in the colanic acid extracellular polysaccharide [43] The role of ... GlcA2)+ and m/z 2301 (GalNAc4, Rib3, GlcA3)+ Similarly to PS-2, the 1D-TOCSY experiments were used to identify the spin systems for each residue and pendant groups of PS-1 The 1D-TOCSY for anomeric ... units was obtained by FAB-MS of the methylated core OS derivative Figure and Table shows a series of A-type primary glycosyl oxonium ions, and secondary ions, of defined compositions at m/z 260fi228...
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Tài liệu Báo cáo Y học: Role of electrostatics in the interaction between plastocyanin and photosystem I of the cyanobacterium Phormidium laminosum ppt
Ngày tải lên :
21/02/2014, 01:21
... shown in the plastocyanin–photosystem I system of Synechocystis [14] and Prochlorothrix [46] It seems reasonable to conclude from Fig by extrapolation that k8 of the plant plastocyanin–photosystem ... the time of chloroplast origin had poorly defined interactions between Cyt f and plastocyanin and/ or plastocyanin and photosystem I, and subsequently the nature of the interactions in the two lineages ... Navarro, J.A (2002) A comparative study of the thermal stability of plastocyanin, cytochrome c6 and photosystem I in thermophilic and mesophilic cyanobacteria Photosynth Res 70, 281–298 Jordan, P.,...
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Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx
Ngày tải lên :
21/02/2014, 15:20
... 2-amino-2-deoxygalactose and lysine The D configuration of GalA and GalN was determined by GLC of the acetylated (S)-2-butyl glycosides and the L configuration of lysine by GLC of the acetylated (S)-2-butyl ... least two types Antibodies of the first type bound to an epitope on LPS of P mirabilis G1 and S1959 Antibodies of the other type bound to another epitope shared by the homologous LPS and LPS of all ... demonstrating the presence of Na-galacturonoyllysine (GalA6Lys) This conclusion was confirmed by typical 13C NMR chemical shifts for the free carboxyl group of lysine (d 177.9) and the amidated carboxyl...
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Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx
Ngày tải lên :
21/02/2014, 15:20
... TSAPDTRPAPGST and the antibody SM3 was determined by Dokurno et al [19] They report a significant contribution of Arg4 to binding by analyzing the surface of the residues covered by the protein They also ... between ˚ the peptide and the non binding bottom of the Fab is 173 A2 which corresponds to about 36% of the interaction of the full peptide with the binding cavity of SM3 The sizes of the surfaces ... ligand ˚ atoms and protein atoms of less than A These additional interactions are solely due to crystal packing and are certainly contributing to the stabilization of the C-terminal portion of the...
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Tài liệu Báo cáo Y học: Antibacterial and antifungal properties of a-helical, cationic peptides in the venom of scorpions from southern Africa pptx
Ngày tải lên :
21/02/2014, 15:20
... in the theory that amphipathicity, a-helicity and cationicity due to the presence of high amounts of lysine and arginine are the most important factors for activity and are important for the ... monocytogenes, melittin acts synergistically with amoxicillin, cefuroxime and erythromycin Parabutoporin and opistoporin enhance the antibacterial activity of cefuroxime Mastoparan shows no synergism ... peptides in the venom of scorpions belonging to the same family, independent of the continent and region where they live In this study, the biological activity of parabutoporin and opistoporin is...
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Tài liệu Báo cáo Y học: Molecular modeling of the dimeric structure of human lipoprotein lipase and functional studies of the carboxyl-terminal domain docx
Ngày tải lên :
21/02/2014, 15:20
... catalytic activity If the substrate recognition site and the catalytic site in the same polypeptide were responsible for catalyzing the lipid substrate, which is the expectation of the head -to- head ... (Fig 4A and B, 5) The lipase activity of the K413A mutant is similar to that of wild type LPL, whereas the esterase activity is reduced to 60% of the wild type and the model structure displays no ... one subunit and the substrate recognition site in the C-terminal domain of the other face each other, thereby bringing together the substrate-binding and catalytic functions in proximity for effective...
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Tài liệu Báo cáo Y học: Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin doc
Ngày tải lên :
22/02/2014, 04:20
... D.W., Gray, E.T Jr, Mazid, M.A., Tom, R.T., Nieboer, E & Sadler, P.J (1994) Dioxygen-induced decarboxylation and hydroxylation of [NiII(glycyl-glycyl-L-histidine)] occurs via NiIII: X- ray crystal ... consequence of the presence of the same kind of spectrum for 4N complexes of GGH, where the a carbon of the His residue is the sole source of chirality [10] However, while positions of the component ... b(MH-jL) log b(HnL), j and n ẳ 2, except for DAHKam, where j ẳ and n ẳ b Ni(II) data from ref [11] c [31] d [36] glycylglycylhistamine, [9] f a-hydroxymetylseryl-a-hydroxymetylserylhistidinamide; Cu(II)...
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Tài liệu Báo cáo Y học: Purification, characterization, immunolocalization and structural analysis of the abundant cytoplasmic b-amylase from Calystegia sepium (hedge bindweed) rhizomes ppt
Ngày tải lên :
22/02/2014, 07:20
... measured by the dinitrosalicylic acid method Inhibition of the enzyme activity by glucose, maltose and cyclohexaamylose For the study of the enzyme inhibition by glucose, maltose and cyclohexaamylose ... b-amylase (Cys83, Cys96, Cys209 and Cys344) are homologous to those found in soybean b-amylase (Cys82, Cys97, Cys208 and Cys343) On the analogy of the soybean b-amylase, the active site of the ... for the b-amylase from C sepium using the X- ray coordinates of the soybean b-amylase (Fig 4) According to the Ramachandran plot of this model the f and c angles of most of the residues are in the...
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Tài liệu Báo cáo Y học: Mutations in the docking site for cytochrome c on the Paracoccus heme aa3 oxidase Electron entry and kinetic phases of the reaction pptx
Ngày tải lên :
22/02/2014, 07:20
... from the so-called high-affinity phase, and the kcat value is derived from the low-affinity phase Positions W121 and Y1 22 A comprehensive set of single mutants in each of the two positions, or of ... all complexes not deviate from that of wild-type by more than a factor of 1.6, the catalytic activity of any mutant in the W121 position is drastically diminished Residual activities for the two ... hand for the docked complex, the interaction domain for cytochrome c on the cytochrome bc1 complex of yeast turned out to be confined to a few residues only [33] Both the mutants H119N and N160D...
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Báo cáo Y học: Electrostatic properties of the structure of the docking and dimerization domain of protein kinase A IIa doc
Ngày tải lên :
08/03/2014, 22:20
... Arg43, and Arg44, of which Arg42 and Arg44 are located in the disordered end A recent study on the flexibility of the full length regulatory subunit of free RIa isoform and complexed with the catalytic ... model of the best (closest to the mean) structure of RIIa D/D, in an orientation rotated by 90° about the x- axis from the orientation of (A) The colours of the two monomers (yellow and grey) and of ... D/D with other parts of the regulatory subunit and the catalytic subunit are currently in progress, with the hope that they might shed light into the importance of the intriguing, highly charged,...
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Báo cáo Y học: Purification and biochemical characterization of some of the properties of recombinant human kynureninase pptx
Ngày tải lên :
08/03/2014, 22:20
... found to be mixed inhibitors of the enzyme (data not shown) The pH optimum was determined as 8.25 and the activity of the enzyme was found to be strongly dependent on the ionic strength of the ... the absence and presence of D,L-3,7-dihydroxydesaminokynurenine (Fig 2), the enzyme appears to be subjected to co-operative modulation by the substrate 3-hydroxykynurenine The mixed inhibition ... Ki¢, and when the lines intersect below the x- axis then Ki > K 0i (in both instances the lines have to intersect to the left of the y- axis) The data obtained for L-kynurenine gave Ki ¼ 20 lM and...
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Báo cáo Y học: Structural and biochemical characterization of calhepatin, an S100-like calcium-binding protein from the liver of lungfish (Lepidosiren paradoxa) docx
Ngày tải lên :
08/03/2014, 22:20
... DEAE-cellulose chromatography, and gel filtration on a Superdex 200 column They were then concentrated with the Centriprep concentrator up to a concentration of 10 mgÆmL)1 and stored at )40 °C Ó ... corresponding to this peak was submitted to sequencing by MS/MS A summary of the sequence analyses and the resulting primary structure of lungfish calhepatin is shown in Fig The protein is composed of 75 ... that the N-terminus is an acetyl group, the molecular mass was calculated to be 8670 Da The alignment of the amino-acid sequence of lungfish calhepatin with other members of the S100 family indicates...
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Báo cáo Y học: Expression and purification of the recombinant subunits of toluene/ o-xylene monooxygenase and reconstitution of the active complex potx
Ngày tải lên :
17/03/2014, 10:20
... to its capacity to modulate the activity of the hydroxylase component of the complex, as it Fig The effect of different ratios of Tomo C (A), Tomo D (B) and Tomo F (C) components with respect to ... oxygenase complexes, like T4MOD [33] and component B of methane monooxygenases [38,39] In these cases the absence of the regulatory subunit induces only a reduction of the hydroxylase activity ... conclusively) its regulatory role in the complex In fact, the 3.6-fold increase in the ability of Tomo H to transform p-cresol into 4-MC, in the absence of any capability of Tomo D to transfer...
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Báo cáo Y học: Propionate CoA-transferase from Clostridium propionicum Cloning of the gene and identi®cation of glutamate 324 at the active site pdf
Ngày tải lên :
17/03/2014, 17:20
... sequenced using standard laboratory protocols The sequence data were analysed using the EXPASY (Expert Protein Analysis System) server of the Swiss Institute of Bioinformatics, the computational ... allowed to proceed for another 10 at 25 °C Aliquots of the samples were assayed for CoA-transferase activity The samples were reductively carboxymethylated and the buffer was exchanged by gel ®ltration ... acids of a protein similar to the 2-hydroxyglutaryl-CoA dehydratase b subunit of A fermentans, was detected upstream of the transferase gene This gene probably encodes one subunit of the (R)lactoyl-CoA...
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Báo cáo Y học: Structural and serological relatedness of the O-antigens of Proteus penneri 1 and 4 from a novel Proteus serogroup O72 pptx
Ngày tải lên :
17/03/2014, 17:20
... established by displacements of the signals for C5 and C6 of GalNAcI to d 73.7 and 68.1, compared with their positions at d 75.7 and 61.9, respectively, in the spectrum of the P penneri polysaccharide, ... of the Gal residue [19] Signi®cant low-®eld displacements of the signals for C6 of Glc, C3 and C4 of Gal, and C3 of GalNAcI to d 66.8, 81.3, 77.1, and 81.6 in the 13C NMR spectrum of the polysaccharide, ... that of Gal by lower-®eld positions of the signals for H2 (d 4.07 and 4.02, as compared to d 3.76, respectively) and by their correlation to the corresponding nitrogen-bearing carbons at d 52.5 and...
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Báo cáo Y học: The opgGIH and opgC genes of Rhodobacter sphaeroides form an operon that controls backbone synthesis and succinylation of osmoregulated periplasmic glucans pot
Ngày tải lên :
17/03/2014, 17:20
... coli, and what properties they confer in this context The highly anionic character of OPGs synthesized by E coli is due to the presence of phosphoglycerol and succinyl residues Two genes mdoB and ... ethanol from the cell pellets The extracts were concentrated by rotary evaporation, and lipids and proteins were then removed by the addition of a mixture of chloroform and methanol (2 : 1) The aqueous ... attached to, or in the close vicinity of, the backbone synthetic enzymes (Y Lequette & J.-P Bohin, unpublished data) Primary substitution by phosphoglycerol residues is catalyzed by another membrane...
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