the use of releasable linkers

... built from the X-ray structure of the C-terminal domain of Ure2p and integrates the finding that the N-terminal domain of Ure2p is flexible An enlargement of the region of Ure2p involved in the interaction ... and another where two Ure2p molecules are bound to one Ssa1p (151 346 Da) Because the binding of the cross -linkers leads to an increase in the molecular mass (Table S1), the number of cross -linkers ... species, were observed in the presence of ATP No change in the mobility of the Ure2p–Ssa1p complexes was detected in the presence of ATP The stoichiometry of Ure2p and Ssa1p within the 120 and 160 kDa...

Ngày tải lên: 15/03/2014, 00:20

... artifacts ), the study is confined to the verbal aspects of the act of giving bad news with the use of politeness and hedging In addition, adjacency pairs are beyond the scope of this paper - The study ... weakeners mentioned above in the scope of the study because of the suitability to the topic of the thesis “Hedging before giving bad news” Weakening particles is to use adverbs as: “really, sincerely, ... “hedges” and these hedging devices attenuate or reduce the strength of the utterance or soften/ weaken the effect of the utterance They damp down its force or intensity or directness By giving the notion...

Ngày tải lên: 07/11/2012, 14:44

... agency of the Department of Agriculture The first is the threat of fire and fuel This year, forest fires have burned more than three million hectares of land That is almost two times as much as the ... starts to accelerate in the second half of this century, as many scientists expect, the area of warm air will be much larger during the summer than it is now The impact on the jet stream will be ... SATISFACTION Over the years, the development of different theories of management and different approached to organization has affected the way we view motivation In the 19th century, the writer Federick...

Ngày tải lên: 07/11/2012, 14:58

... overview of the study in which the rationale for the research, the research problem, the purposes, the research questions, the scope of the study, the research method, the significance of the study, ... terms of: (1) The height of the bulk of the tongue in the mouth (2) The front/back position of the tongue in the mouth (3) The degree of lip-rounding (4) The length of vowels (Roach, 1998: 13-14) ... have the habit of pronounce a new-formed word according to the pronunciation of the root one For example, they tend to pronounce the sounds of Exhibition like the sound of Exhibit With the help of...

Ngày tải lên: 07/11/2012, 14:58

... thương hiệu, khách hàng, dịch vụ, đầu tư phát triển kỹ nhân viên Bước - Kế hoạch theo dõi điều chỉnh: Các công cụ theo dõi đánh giá thực kết thu qua giai đoạn cụ thể - 22 1.3 Kinh nghiệm chiến ... lược Marketing du lịch nước: Tư tưởng Marketing giới phát triển theo ba xu hướng chính: Xu hướng Mỹ: Chú trọng phát triển Marketing theo hướng nghiên cứu quan hệ định hướng thị trường hoạt động ... tăng lên, chất lượng sống người ngày cải thiện tạo động thúc đẩy du lịch phát triển không ngừng Theo luật du lịch ban hành tháng 6/2005 thì: “Du lịch hoạt động có liên quan đến chuyến người nơi...

Ngày tải lên: 08/04/2013, 17:02

... column to keep the moisture content inside the column uniform while water was sprinkled over the top of the medium until the outflow from the bottom of the column equaled the volume of the water input ... differences in the values of the distribution coefficient of two soils Given the fact that the distribution coefficient depends on the specific surface of the medium, Andisols provide the diversity of transport ... To compare the change of BTCs in the same flow condition of Reynolds number, the variation of first and second temporal moments as a function of the mixture ratio of - 358 - Journal of Water and...

Ngày tải lên: 05/09/2013, 10:15

... illustrates the efficiency of the reactors for the removal of TP The highest efficiency for the removal of TP was obtained upon using reactor II, and the maximum removal rate is 80% The least efficient ... a certain extent, because the radius of H+ is less than the radius of K+, Na+ and Ca2+ The H+ ion replaces the positive ion K+, Na+, Ca2+ hole volume is enlarged, force of chemical bond between ... microcells, then the iron could be reduced The reaction can reduce the toxicity of pollutants, promote growth of microorganism in reactors especially biological degradation for pollutants, then, lower the...

Ngày tải lên: 05/09/2013, 10:17

... Acknowledgements Abstract Table of contents PART I: INTRODUCTION Rationale of the Study Significance of the Study Scope of the Study Aims of the Study Overview of the Study PART II: DEVELOPMENT ... in the language classroom This may be a composite of the classroom itself, the lesson routines, the audio-visual aids, etc The triangle of the teacher, the learner and the environment are the ... attitudes • the extent of teacher’s responsibility • - the philosophy of the school the general pattern of staff behaviour The classroom itself: • • the temperature/ fresh air • the acoustics • the lines...

Ngày tải lên: 07/09/2013, 13:06

... that the frequency of the use of the speech act of refusal by the Australian NSs of English was different from that by the VLEs Although the VLEs and the Australian NSs of English employed the ... according to the status of the interlocutors The above review of the related literature of the speech act of refusal shows that the use of refusal strategies by Vietnamese learners of English is ... Order of semantic formulas Excuse(5) Offer of alternative (7) NSEs The example in the table shows that there are statements of regret of the responses by the VLEs expressed in the first position of...

Ngày tải lên: 07/09/2013, 13:31

... setInterval() action To remove the functionality of the setInterval() action, use the following syntax: clearInterval(myInterval); Using the syntax shown, you can initiate the setInterval() action ... turned on and off by assigning a variable name, as in the following example: var myInterval:Object = setInterval(rotateClip, 1500); This example assigns the name myInterval to the setInterval() ... action is set up to call the rotateClip() function every 1.5 seconds (1,000 milliseconds equals second) If you want to pass arguments to the called function, simply add them to the setInterval() action:...

Ngày tải lên: 20/10/2013, 14:15

... notify the FDA of their intent to market new products However, they are not required to establish the safety or the effectiveness of their products Once a dietary supplement is on the market, the ... interactions with concomitant use of other drugs and alcohol (Mathews et al., 2002) Because of these reports, regulatory agencies in Europe and Canada now warn consumers of the potential risks associated ... which often tend to be slow acting or require administration of prescribed doses over an extended period of time (not hours or days, but weeks) 14.3 Risks in the Use of Medicinal Herbs The use of...

Ngày tải lên: 25/10/2013, 05:20

... elucidation of specific biosynthetic enzymes, and the identification of end-products The complete genetic makeup of an organism has been generated in the plant sciences as well Because of the success of ... example, the flow of precursors into the disrupted pathway often results in the accumulation of one or more intermediates upstream of the blocked step This is because elevated concentrations of the ... All of these data are then used in the second step to reconstruct the biochemical reaction networks that underlie the cellular function of interest When such data are put into the format of a...

Ngày tải lên: 25/10/2013, 05:20

... effect on the adenoma formation Taken together, the results of these three groups, the efficacy of berry preparations, Mirtoselect from V myrtillus, and C3G in the Min/+ mouse, warrant the further ... out of use by 1745 due to inappropriate use (Wilkins et al., 1985) Dr William Withering introduced foxglove back to the medical profession in An Account of the Foxglove and Some of Its Medical Uses: ... intervals measure the robustness and stability of the estimate of the response rate ratio, and if the confidence interval excludes 1.0, then there is a statistically significant association In the larger...

Ngày tải lên: 25/10/2013, 05:20

... getting the same result; hence there is less variability in the data The typical measure of the variability of the data is the SD 51 Section 3: Chance The third factor, also frequently ignored, is the ... ignored, is the effect size: the larger the effect size, the greater the power of the study; the smaller the effect size, the lower the statistical power Sometimes, an effect of a treatment might be ... analyzed at the end of the study (as in completer analysis where dropouts before the end of the study are not analyzed), then one cannot be sure that the two groups at the end of the study are...

Ngày tải lên: 01/11/2013, 11:20

... the functionality of SJ-2000 jacks The use of this jack allows instantaneous signal rerouting Patch panels act as the mechanical support for the jacks The two rear connectors are bridged as the ... Dynamic Reconfiguration of Indoor Combination Networks Through the Use of Patch Panels Alternative Through the Use of Radiofrequency Patch Panel 2000 homes in optical nodes ... resulting in the following advantages: • As the ratio changes, there is no effect on the fixed cabling as all the fixed cabling is on the rear side of the patch panels • Changes can be made without...

Ngày tải lên: 10/12/2013, 18:15

... presented by Doff (1988) and the other by Darn (2008), results from the different angels of views and focuses However, both of them agree on the fact that questions are used for the main purpose of checking ... given in the textbooks Also, they are not aware of whether these tasks are effective for them or not Nevertheless, they express their desire for some types of language activities that they have ... work are only the way that an activity is done not a kind of activity Because of it, the result of the survey was not completely exact One of the pioneering studies on the application of eliciting...

Ngày tải lên: 18/12/2013, 10:03

... know their mother tongue It is known that the habits of their mother tongue affect their acquisition of the second language They use their previous experience of their first language as a means of ... and their causes 2.7.1 Errors and their causes in section of test 2.7.2 Errors and their causes in section of test 2.7.3 Errors and their causes in section of test 2.7.4 Errors and their causes ... going to the beach today Neither you nor I am prepared for the exam (2) Concord of verb and "there" as subject The form of the verb depends on the number of the noun nearest to it E.g: a There is...

Ngày tải lên: 18/12/2013, 10:04