the twin twin transfusion syndrome evolving concepts
Tài liệu Báo cáo khoa học: Evidence for interactions between domains of TatA and TatB from mutagenesis of the TatABC subunits of the twin-arginine translocase docx
Ngày tải lên :
19/02/2014, 17:20
... rearrangements of the TM spans of these subunits It has not been established whether these TM spans simply anchor the amphipathic regions and cytosolic 2272 domains to the membrane, or whether they serve ... conjunction with the data shown in Fig 6, these data show that the severe effects of the TatA ⁄ 3Gly mutations can be rescued by the presence of additional mutations either elsewhere in the TatA TM ... expressing the various mutated subunits, and the data for the TatA and TatB mutants (expressed using the pBAD vector) are shown in Fig The expression of the wild-type tatABC from the pBAD-ABC...
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Báo cáo khoa học: The Rieske protein from Paracoccus denitrificans is inserted into the cytoplasmic membrane by the twin-arginine translocase doc
Ngày tải lên :
07/03/2014, 11:20
... in the cytosolic and membrane fractions of the C152S mutant, demonstrating: (a) the inability of the mutant to insert a cofactor, and (b) the specific origin of the signal in the other samples The ... contrast, both the R16K mutation and the R15K ⁄ R16K double mutation result in almost complete loss of the signal in the membrane fraction The bands for the Y20K mutant resemble the wildtype, ... transport depends on the presence of the Tat consensus motif However, as in the case of the thylakoid ISP and in contrast to the majority of other Tat substrates, transport of the P denitrificans...
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Episode 7 The twin docx
Ngày tải lên :
15/03/2014, 17:20
... understand If you are there, then who is in the bathroom? Episode The Twin What?!! BRIDGET What? Ahhhhhhhh! Annie, what are you doing? ANNIE But you're, you're … ! BRIDGET … Twins ANNIE Bridget, ... that the other box is empty HECTOR Hey! She's going round the back ANNIE OK, gentlemen, place your bets, please Which box you think Bridget is in? NICK The box on the left HECTOR No, no, the box ... something to ask you Episode The Twin ANNIE Yes, Hector? HECTOR The thing is, you like to come to the cinema tomorrow night with me? ANNIE Pardon? HECTOR Would you like to come to the cinema tomorrow...
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Báo cáo khoa học: The twin-arginine translocation (Tat) systems from Bacillus subtilis display a conserved mode of complex organization and similar substrate recognition requirements doc
Ngày tải lên :
16/03/2014, 04:20
... and the mobilties of molecular mass markers (in kDa) are indicated on the left strates [8] Within the DmsA signal peptide we found that the twin arginine motif, the )1 serine residue and the ... the membrane if not exported (much of the membrane-bound GFP was incorrectly folded, suggesting a nonspecific interaction rather than a specific interaction with the translocon) Nevertheless, these ... targeted to the cell wall, where it is involved in the release of inorganic phosphate [20] The absence of a TatB component led to the idea that the TatAd protein may be bifunctional, fulfilling the roles...
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Báo cáo toán học: "On the twin designs with the Ionin–type parameters" doc
Ngày tải lên :
07/08/2014, 06:20
... note that there is a similarity between the way that we get twin designs from Bush–type Hadamard matrices and the way that the twin designs with the Ionin–type parameters are obtained from the weighing ... such matrices exist, then the construction method given in this paper simplifies Ionin’s method substantially On the other hand the non–existence of these matrices would imply the non–existence of ... for our construction For completeness we include the following result of the author [5] Theorem Let 4n be the order of an Hadamard matrix, then there is a Bush-type Hadamard matrix of order 16n2...
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Nanog in the twin fish models medaka and zebrafish functional divergence or pleiotropy of vertebrate pluripotency gene
Ngày tải lên :
14/09/2015, 08:45
... PGCs) are created in one part of the embryo, often far away from their final destination They must then migrate to the somatic part of the future gonads, where they become mature germ cells — ... (blastoderm) atop the yolk During cleavage, the volume of the embryo remains essentially constant, so that the divisions produce a larger number of smaller cells The cells in the blastoderm form the embryo ... Lixiu and Yan Yan for their kind help and the happy time they brought to the lab I also thank Liang Dong, Li Yan, Xiang Wei, Wang Xingang, Li Zhen, and Zhan Huiqin for their kind help in zebrafish...
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Báo cáo y học: "The Systemic Inflammatory Response Syndrome (SIRS) in acutely hospitalised medical patients: a cohort study"
Ngày tải lên :
25/10/2012, 09:56
... interests The authors declare that they have no competing interests Authors' contributions PC contributed to the design of the study, obtained data, made the analysis, interpreted the data and wrote the ... patients were registered on arrival by the nurses The data were collected a few minutes after the patient arrived in the ward The nurses were aware of the study and were repeatedly reminded to ... conclusions from the opposite setting It is important to remember that the results reflect the standard of care in the actual ward, which is not necessarily generalisable to other wards As in other studies...
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Tài liệu The Mare Reproductive Loss Syndrome and the Eastern Tent pptx
Ngày tải lên :
13/02/2014, 15:20
... 2003.48 parison with the sensitivity of nonpregnant horse, mice, rats, and possibly other animals) is the next step in the syndrome Step Variable Defense Resources The final step is the poor antibacterial ... each of the MRLS-associated syndromes is local bacterial infection of hematogenous origin, with the bacteria initially entering the blood stream at the site of exposure to the caterpillar The cardiac ... through the lung capillary beds and into the systemic circulation An obvious mechanism is movement of the material through the lungs in the same way they enter into and move through the intestine...
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Tài liệu The Java EE 6 Tutorial Basic Concepts Fourth Edition pptx
Ngày tải lên :
18/02/2014, 05:20
... Figure 1–2 shows the various elements that can make up the client tier The client communicates with the business tier running on the Java EE server either directly or, as in the case of a client ... network services The description includes the name of the service, the location of the service, and ways to communicate with the service WSDL service descriptions can be published on the Web GlassFish ... Model The Java EE application model begins with the Java programming language and the Java virtual machine The proven portability, security, and developer productivity they provide forms the basis...
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Báo cáo khoa học: "Semantic Retrieval for the Accurate Identification of Relational Concepts in Massive Textbases" ppt
Ngày tải lên :
17/03/2014, 04:20
... in GENA and the UMLS meta-thesaurus1 Table shows the size of the original database and the number of entries expanded by name variations Terms in MEDLINE were then identified by the longest matching ... of the word ID of modifying phrase ID of the X-th argument of the word event type sentence’s ID whether gene, gene prod, or disease ID in GENA ID in the UMLS meta-thesaurus short form of the ... X-2 clarifies the effect of using the term ontology Comparison of X-2 and X-3 shows the effect of the event expression ontology The results for X-3 indicate the maximum performance of the current...
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The Java EE 6 Tutorial Basic Concepts Fourth Edition ppt
Ngày tải lên :
17/03/2014, 12:20
... Figure 1–2 shows the various elements that can make up the client tier The client communicates with the business tier running on the Java EE server either directly or, as in the case of a client ... network services The description includes the name of the service, the location of the service, and ways to communicate with the service WSDL service descriptions can be published on the Web GlassFish ... Model The Java EE application model begins with the Java programming language and the Java virtual machine The proven portability, security, and developer productivity they provide forms the basis...
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Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx
Ngày tải lên :
23/03/2014, 07:20
... together, these data suggest that the RS-rich region of the SARSCoV N protein is possibly phosphorylated by SRPK1 Phosphorylation of multiple serines within the RS motif The RS motif of the SARS-CoV ... examined whether the SARS-CoV N protein plays a role in premRNA splicing due to the presence of the RS motif but, so far, we not have any evidence to support this hypothesis (data not shown) In the present ... are located in the cytoplasm as well as in the nucleolus [34,35] Nevertheless, the SARS-CoV N protein does not localize substantially to the nucleolus [36,50], as also observed in the present study...
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Báo cáo khoa học: Distribution of the extrinsic proteins as a potential marker for the evolution of photosynthetic oxygen-evolving photosystem II ppt
Ngày tải lên :
23/03/2014, 15:21
... with the result of Shibata et al [21] The presence of PsbV in C paradoxa is consistent with the presence of the psbV gene in the complete sequences of the cyanelle genome [24], in which the psbU ... elucidate the evolutionary process of the oxygenevolving complexes In addition to these biochemical studies, genomewide analysis of the extrinsic proteins has been largely advanced, owing to the sequencing ... Among the extrinsic proteins, the 33 kDa protein (PsbO) which plays an important role in maintaining the stability and activity of the manganese cluster is present in all of the oxygenic photosynthetic...
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Báo cáo khoa học: "THE TEXTUAL DEVELOPMENT OF NON-STEREOTYPIC CONCEPTS" potx
Ngày tải lên :
01/04/2014, 00:20
... (re-)integrates them coherently into the already existing view The concepts constructed in the view during discourse provide the text specific perspective on the background knowledge The layer of the referentialstructure ... on the concepts of the background knowledge A discourse state is defined by the actual state of all the five layers of the text representation, which renders the actual state of the view and the ... clustering This trace represents the progression of themes and the development of focusing The notion of thematic structure is based on the Prague School approaches to the thematic organization (e.g...
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Báo cáo sinh học: " The Severe Acute Respiratory Syndrome (SARS)-coronavirus 3a protein may function as a modulator of the trafficking properties of the spike protein" docx
Ngày tải lên :
18/06/2014, 22:20
... Furthermore, the juxtaposition of the YxxΦ motif and a ExD (diacidic) motif was found to be essential for the transport of 3a to the cell surface, consistent with the role of these motifs in the ... the plasma membrane into the endosomes Interaction between the adaptor protein complex (AP-2) with the YxxΦ motif present in the cytoplasmic domain of the internalizing protein concentrated the ... decrease in the expression of S on the cell surface Thus, this viral-viral interaction confers the functional role for the YxxΦ motif found in other coronaviruses to the SARS-CoV S This hypothesis...
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Báo cáo hóa học: "Assessment of nutritional knowledge in female athletes susceptible to the Female Athlete Triad syndrome" pot
Ngày tải lên :
20/06/2014, 00:20
... essential in the evaluation of the Triad [26] It is therefore important to stress that this study examined 'at risk' behaviour of the Triad rather than the occurrence of the disorders themselves ... with the same respondents two weeks later The final survey packet contained the following tests: i) Disordered eating was assessed with the EAT-26 [20] The EAT-26 is a shortened version of the ... concept and design, analyses the data and drafted the manuscript; EQ contributed to the interpretation of the results and drafted the manuscript All authors read and approved the final manuscript References...
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báo cáo hóa học:" The Severe Acute Respiratory Syndrome (SARS)-coronavirus 3a protein may function as a modulator of the trafficking properties of the spike protein" docx
Ngày tải lên :
20/06/2014, 04:20
... Furthermore, the juxtaposition of the YxxΦ motif and a ExD (diacidic) motif was found to be essential for the transport of 3a to the cell surface, consistent with the role of these motifs in the ... the plasma membrane into the endosomes Interaction between the adaptor protein complex (AP-2) with the YxxΦ motif present in the cytoplasmic domain of the internalizing protein concentrated the ... decrease in the expression of S on the cell surface Thus, this viral-viral interaction confers the functional role for the YxxΦ motif found in other coronaviruses to the SARS-CoV S This hypothesis...
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Báo cáo y học: "Is vitamin D deficiency involved in the immune reconstitution inflammatory syndrome?" pptx
Ngày tải lên :
10/08/2014, 05:21
... 1,25(OH)2D locally at the site of inflammation Protease inhibitors (PI) inhibit the function of the hepatic-CYP3A4 and the macrophage-CYP27B1 which are critical for active vitamin D synthesis, and exert ... and Therapy 2009, 6:4 http://www.aidsrestherapy.com/content/6/1/4 could result in an increased risk of IRIS in patients treated with a PI-based regimen [29] Testing the hypothesis Our hypothesis ... [46] Implication of the hypothesis There is an inter-relationship between vitamin D metabolism, HAART therapy and immunity Impaired vitamin D metabolism in macrophages, whether caused by vitamin...
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Báo cáo y học: "Leukocyte oxygen radical production determines disease severity in the recurrent Guillain-Barré syndrome" doc
Ngày tải lên :
11/08/2014, 03:20
... between the individual attack frequency (shorter interval between relapses including the time from the onset to the second relapse) and respiratory burst, indicating a higher tendency for the disease ... (produced by the NADPH oxidase) consuming MPO-H2O2-halide system Our findings therefore suggest that the overall function of the oxidase is intact in patients with severe RGBS, and that the reduced ... the subject of further study, along with studies outlining the role of leukocyte-derived oxygen radical for other autoimmune diseases Acknowledgements This work was supported by grants from the...
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Báo cáo y học: "Status dystonicus resembling the intrathecal baclofen withdrawal syndrome: a case report and review of the literature" pptx
Ngày tải lên :
11/08/2014, 03:21
... as neuroleptic malignant syndrome, malignant hyperthermia and serotonergic syndromes [6-8] Whether the clinical features observed are the result of a true withdrawal syndrome representing physiological ... reports are described in the literature and the term ‘ITB withdrawal syndrome has been used to define them Comparisons have been drawn between ITB withdrawal syndrome and other acute, life-threatening ... ITB withdrawal; the case serves as a caution against over-diagnosing ITB withdrawal syndrome and highlights the possibility that, the complications observed in “ITB withdrawal syndrome, ” and exceptionally...
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