the tissue engineering approach
Tissue engineering approaches to tendon repair studies on the use of bone marrow stromal cells and knitted poly (d, l lactide co glycolide scaffold
... Strehlow 1969) The organization of the extracellular matrix molecules of the tendon is the principal determinant of the physical function of this tissue The degree to which tissue engineering approaches ... loop is a measure of the energy that is lost during the loading-unloading test of the tendon; it therefore is an indication of the viscous properties of the tissue (Butler 1978) The mechanical properties ... With time, the scar tissue may assume some of the characteristics of the tendon, but complete regeneration does not appear to occur The goal of tissue engineering approaches is to improve the quality...
Ngày tải lên: 17/09/2015, 17:18
báo cáo hóa học: " An overview of tissue engineering approaches for management of spinal cord injuries" docx
... have shown the ingrowth of axons from the rostral stump into the bridge, but the axons did not leave the bridge On the other hand, the transduced neurons in the caudal stump extended their processes ... to have the same mechanical properties similar to the spinal cord [175177] They are nonbiodegradable materials The advantage of these materials over the biodegradable materials is that they not ... enter the distal stump [78] In another experiment, instead of infusion of BDNF distal to the implant, the BDNF was added to the SC/ Matrigel cable inside the PAN/PVC guidance channels This approach...
Ngày tải lên: 19/06/2014, 10:20
Tissue engineering approach for annulus fibrosus regeneration
... the tissue culture environment without the use of trypsin, onto the scaffolds and other tissue engineering constructs (Kikuchi et al 1998) There have been studies done on 10 the benefits of the ... would be another contributing factor to IVD degeneration, as the disc is the largest avascular tissue in they body The nearest blood supply is found within the cartilage end-plates of the vertebral ... study the effects on the BMSC cell-sheet and determine the feasibility of the 12 assembly to be used for AF tissue engineering in the future 13 14 All the above mentioned objectives would lead the...
Ngày tải lên: 11/09/2015, 09:57
Tissue engineering approach to anterior cruciate ligament reconstruction
... connective tissue also supports the neurovascular elements of the ligament [13] These individual fascicles are either oriented in a spiral fashion around the long axis of the ligament or they pass ... restricted their use in tissue engineering applications [42] On the other hand, adult MSCs and other tissue- specific stem cells are present in large quantities in the human body; hence, there are ... Polysaccharides differ in the composition of the monomeric unit, the linkages between them, and the ways in which branches from the chains occur Except for the demand from tissue engineering for...
Ngày tải lên: 16/09/2015, 08:30
Báo cáo y học: "Tissue engineering in the rheumatic diseases" ppsx
... disadvantages hamper the prevalence of ACI: (a) the nonuniform spatial distribution of chondrocytes and the lack of initial mechanical stability, (b) the suture of the periosteal flap into the surrounding ... Figure PubMed entries for tissue engineering in the rheumatic diseases (a) The first entry for the key word tissue engineering’, also called ‘regenerative medicine’, in the National Center for ... toward joint tissues and to orchestrate tissue repair effectively (reviewed in [30]) Mesenchymal stem cells for joint tissue engineering As with the key word tissue engineering’, the number of...
Ngày tải lên: 09/08/2014, 01:22
Vascularised bone tissue engineering endothelial progenitor cells and human mesenchymal stem cells coculture in 3d honeycomb scaffolds and the effect of bi rotational bioreactor and hypoxic microenvironment 1
... subsequent transplantation in the mandible Figure 2-9 Graphical representation of the molecular weight loss of the 3D scaffold with respect to the growth and remodelling of the tissueengineered constructs ... the age and health status of the patient, as well as the difficulty in graft shaping for filling of defect sites hamper its use The need for two surgeries on the same patient also increases the ... my proposed BTE approach and the individual BTE components, as well as its relation with the natural bone Detailed justification of the proposed BTE approach will be discussed in the next chapter...
Ngày tải lên: 09/09/2015, 10:16
Improving the mechanical and functional performance of extrusion based additive manufactured scaffolds for bone tissue engineering
... collector [16] Therefore, a simple combinational approach should be developed to improve the cell seeding efficiency, and thereby to improve the functional performance of the scaffolds The hypothesis, ... that the scaffold is retained until the fracture is remodelled by the host tissue [6] Specially, it was proposed that the implanted scaffolds should match the stiffness and strength of native tissue ... elaborated in the following sections 1.3 Research hypothesis and objectives Having the above mentioned challenges in mind the following hypothesis can be formed: “To further improve the range of...
Ngày tải lên: 10/09/2015, 15:51
Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 1
... using these films as scaffolds to complement the cell sheet approach The aim of the present thesis was to investigate the use of PCL films as scaffolds in layered tissue engineering, using the ... assembly, the tissue construct can be more quickly implanted, as there is no need for extended in vitro culture for maturation Furthermore, the substrate cues can be introduced to the material, or the ... situation compounded by the inability of the host to remodel the graft The synthetic SMCs invade the tunica intima, resulting in neointimal hyperplasia and re-occlusion of the vessel Some work is...
Ngày tải lên: 14/09/2015, 08:49
Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 2
... Characterisation Of Vascular Progenitors Figure 4-3: Primary culture of haemopoietic tissue in EGM Following culture in endothelial cell media, outgrowth colonies were generated from (a) umbilical cord ... spindle morphology (c) When cultured in the same medium, fibroblastic cells quickly grew out from fetal liver mononuclear cells, and failed to express endothelial phenotype 122 Chapter Isolation...
Ngày tải lên: 14/09/2015, 08:49
Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 3
... medium, the adhered fibroblasts and MSC quickly outgrew the EPC population To verify the presence of haematopoietic and endothelial lineage cells in the liver, I studied the expression profile of the ... expansion resulted in the generation of a haemangioblast-like population However, these cells were incapable of further expansion In the light of these findings, UCB currently represent the best source ... during the 18th week of gestation (Nava 2005), further suggesting the presence of EPC in the liver The discrepancies in numbers can be explained by difference in isolation techniques, as well as the...
Ngày tải lên: 14/09/2015, 08:49
Development of cell sheet constructs for layer by layer tissue engineering using the blood vessel as an experimental model 4
... onto the respective surface to generate bio-synthetic cell sheet constructs, which can then be assembled to form stratified tissue 7.2 Hypotheses The aim of this project was to examine whether the ... biomolecules These developments contribute towards improved biocompatibility of the tissue engineering scaffolds In the specific context of vascular tissue, two other important classes of tissue responses ... grafting, and then the introduction of an N1speak following the conjugation of the CD34 antibody, indicating presence of the protein High resolution surveys of the C1s core spectra revealed the presence...
Ngày tải lên: 14/09/2015, 08:49
Nanofabrication, architecture control, and crosslinking of collagen scaffolds and the potential in corneal tissue engineering application
... throughout Then the salt crystals are leached away using water to form the pores of the scaffold The process is easy to carry out The pore size can be controlled by the size of the salt crystals and the ... growth in the shape dictated by the scaffold so as to replace the damaged tissue The requirements of scaffolds for tissue engineering are complex and specific to the structure and function of the targeted ... certain distance from the polymer solution With the increase of the voltage charged on the polymer solution, the pendent drop of the polymer solution formed at the tip of the capillary is deformed...
Ngày tải lên: 14/09/2015, 09:33
Application of rapid prototyping technology to the fabrication of 3d chitosan scaffold for tissue engineering
... by the system computer The binder is delivered to the powder bed to produce the first layer and the bed is then lowered by a fixed distance Powder is then deposited and spread evenly across the ... top of the first and a heated roller passes over the two squeezing and bonding them together The entire object is formed in this way The downside in this process is the burnt edges due to the laser ... the first layer, the base is rotated by 90 degrees and the dispensers are lifted to a higher level that allows for the chitosan gel for the next layer to lie on the previous layer The robot then...
Ngày tải lên: 30/09/2015, 13:49
Incorporating english cultural elements into english training with the comparing - contrasting approach: A case of tourism students at haiphong community college part 3
... the task sheets Then divide the class into groups of three or four Explain the task to the students They are to work together in groups, studying the schedule and answering the questions on the ... activities as they are the most reliable data, or to check the reliability of the data collected from other sources- the survey questionnaire The author of the study observed the C.QDL 05.2 The observation ... respectively) From the discussion, the students say that they care work element most because they think it will help them with their future jobs Besides, they confide that they want to learn the other English...
Ngày tải lên: 07/11/2012, 15:06
INCORPORATING ENGLISH CULTURAL ELEMENTS INTO ENGLISH TRAINING WITH THE COMPARING CONTRASTING APPROACH a CASE OF TOURISM STUDE
... the task sheets Then divide the class into groups of three or four Explain the task to the students They are to work together in groups, studying the schedule and answering the questions on the ... activities as they are the most reliable data, or to check the reliability of the data collected from other sources- the survey questionnaire The author of the study observed the C.QDL 05.2 The observation ... respectively) From the discussion, the students say that they care work element most because they think it will help them with their future jobs Besides, they confide that they want to learn the other English...
Ngày tải lên: 07/09/2013, 13:41
Biodegradable Polymers as Scaffolds for Tissue Engineering
... compensate for the loss of the missing liver tissue The amount of liver regenerated is equivalent to the amount of liver removed The liver regenerates by the proliferation of the existing tissues The regenerating ... Regeneration There are two modes of tissue engineering for tissue construction One is in vitro (ex vivo) tissue engineering and the other in vivo (in situ) tissue engineering In the beginning of tissue ... epidermis The exposed connective tissue of the wound – the granulation 343 344 14 Biodegradable Polymers as Scaffolds for Tissue Engineering tissue – contracts to tug the wound edges together and,...
Ngày tải lên: 25/10/2013, 08:20
The electrical engineering handbook CH107
... coefficients in the same manner as the coefficient of utilization The room position multiplier is a function of the room cavity ratio and of the location in the room of the point where the illumination ... both Reduce the area of high luminance causing the glare condition Increase the angle between the glare source and the line of vision Increase the luminance of the area surrounding the glare source ... Ratios The ability to see details depends on the contrast between the detail and its background The greater the contrast difference in luminance, the more readily the seeing task is performed The...
Ngày tải lên: 30/12/2013, 22:33
The electrical engineering handbook CH051
... tensile stress in the x-direction, for example, will strain the lattice in the xy-plane and destroy the three-fold symmetry, thereby lifting the degeneracy of the energy minima However, the four-fold ... permission.) According to the deformation potential theory, the strain will shift the energy of all the states in a given band extremum by the same amount, i.e., the valley moves along the energy scale ... perpendicular to the valley For an applied E field parallel to the stress, the conductivity will increase (i.e., the resistivity decreases) relative to the unstressed state because of the increase in the number...
Ngày tải lên: 30/12/2013, 22:33