the tibial 1 pioneer pathway an in vivo model for neuronal outgrowth and guidance
Báo cáo khoa học: " The complete genomic sequence of an in vivo low replicating BLV strain" pps
Ngày tải lên :
12/08/2014, 04:21
... sequences These include: 1) a deleted C (base 14 41) , and TAGT (bases 15 21 15 24) in the BLV CG p24 gag sequence; 2) an inserted C (base 2202) in the BLV GAGA protease sequence; and 3) an inserted ... of the BLV A Tax is shown, and the rest is indicated by the an wavy lines In the Env proteins the N-linked glycosylation sites are shown in bold, while the neutralizing domains (ND), the transmembrane ... shown In the GIV protein the two putative cellular protease cleavage sites are indicated by an inverted triangle and the amino acid myb-like motif (MYB) and the arginine-rich nucleus targeting...
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Báo cáo khoa học: " The complete genomic sequence of an in vivo low replicating BLV strain" pot
Ngày tải lên :
12/08/2014, 04:22
... sequences These include: 1) a deleted C (base 14 41) , and TAGT (bases 15 21 15 24) in the BLV CG p24 gag sequence; 2) an inserted C (base 2202) in the BLV GAGA protease sequence; and 3) an inserted ... of the BLV A Tax is shown, and the rest is indicated by the an wavy lines In the Env proteins the N-linked glycosylation sites are shown in bold, while the neutralizing domains (ND), the transmembrane ... shown In the GIV protein the two putative cellular protease cleavage sites are indicated by an inverted triangle and the amino acid myb-like motif (MYB) and the arginine-rich nucleus targeting...
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Báo cáo khoa học: A steady-state modeling approach to validate an in vivo mechanism of the GAL regulatory network in Saccharomyces cerevisiae ppt
Ngày tải lên :
07/03/2014, 16:20
... [Gal3p]max 2.0 · 10 )10 M 0.4 1. 0 1. 0 · 10 )7 M 1. 0 · 10 )10 M 5.0 · 10 )11 M 6.3 · 10 )11 M 1. 0 · 10 )10 M 30 0.5 · 2.372 · 10 )11 · 2.372 · 10 )11 5.47 · 10 )9 M 1. 0 · 10 )6 M 5.0 · 10 )6 M M M ... vitro binding coefficients Further results from studies in molecular biology and bioinformatics can limit the number of candidate models Finally, the relevance of the different mechanisms at the ... two binding site for Gal4p Molar balance equations The following are the molar balance equations for the four candidate models after considering interactions specific to the model: Model I ½D1t...
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The development of an in vivo humanized mouse model to investigate epstein barr virus infection and tumorigenesis
Ngày tải lên :
10/09/2015, 09:22
... seen in the first year post- transplant124 The overall incidence of PTLD is - 2% The incidence of the disease in renal and liver transplant is – 5%, in heart and heart-lung transplant is – 15 %, and ... 15 %, and in intestinal transplant is 10 – 15 % 12 5 The incidence of PTLD in bone marrow transplant is 0.5% in HLA-matched 32 Humanized mouse model of EBV infection Introduction transplants and rises ... of the NK activating ligand MIC-B, thereby nullifying the susceptibility of the infected cells to NK-mediated lysis 21 1.2.4 EBV and the human cytokine system Both acute lytic EBV infection and...
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Báo cáo khoa học: A simple in vivo assay for measuring the efficiency of gene length-dependent processes in yeast mRNA biogenesis doc
Ngày tải lên :
07/03/2014, 12:20
... SUA7 (strains FP177, FP207 and FP142) (D) tfa1-T 218 D, tfa1-C127F and an isogenic TFA1 (strains YSB326, YSB3 31 and YSB324) (E) srb10D, srb11D and an isogenic wild type (strains SLY7, SLY107 and SLY3) ... supported by the Ministry of Education and Science of Spain (grant BMC200307072-C03- 01 to SC and fellowships to MM-H and to MV), and by the Andalusian Government (CVI2 71) 10 11 12 13 References 14 Aguilera ... FY 710 and FY120) (D) GLAM ratios of htz1D, swr1D, isw1D, chd1D, rpd3D and an isogenic wild type (strains Y 017 03, Y03693, Y03385, Y0 616 0, Y 011 14 and BY47 41) Fig In uence of mutations affecting...
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Báo cáo khoa học: Insertion of the plant photosystem I subunit G into the thylakoid membrane In vitro and in vivo studies of wild-type and tagged versions of the protein doc
Ngày tải lên :
07/03/2014, 21:20
... His and Strep tags in PSI-G constructs and transformed plants were treated separately with thermolysin and trypsin as described for the in vitro import analyses PSI-G, and a control protein, ... the control of the 35S promoter and terminator For each tagged variant and the wild-type PSAG, a cassette containing the PSAG construct flanked by the 35S promoter and terminator was excised and ... C-terminally and looptagged PSI-G can insert into the thylakoid in vivo (Figs and 5), it is possible that the tags hinder assembly into PSI complexes Therefore, it was of interest to find out whether...
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Báo cáo Y học: NMR structure of the HIV-1 regulatory protein Vpr in H2O/trifluoroethanol Comparison with the Vpr N-terminal (1–51) and C-terminal (52–96) domains pot
Ngày tải lên :
31/03/2014, 23:20
... may expose the N-terminal (1 39) portion of the protein and allow its tight binding to Lys-tRNA synthetase [15 ] The C-terminal domain (52–96)Vpr and not the N-terminal domain (1 51) Vpr, has been ... been suggested that these findings could be explained by an interaction between the N- and C-terminal domains in the intact Vpr protein resulting in steric hindrance in the C-terminal recognition ... (in pink) and (52–96)Vpr (in green) domain structures The (17 –46) domain backbone of the N-terminal (1 51) Vpr (pink) is superimposed with the (17 –46) domain backbone of the intact protein ˚ (1 96)Vpr...
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báo cáo hóa học:" An in vivo evaluation of bone response to three implant surfaces using a rabbit intramedullary rod model" doc
Ngày tải lên :
20/06/2014, 04:20
... dehydrated in absolute alcohol and de-fatted in 50% mixture of ether and acetone before being placed in 10 0% alcohol again for 12 hours Methods Implants for intramedullary implantation in rabbit ... harvested, cleaned of soft tissue, and fixed in 70% ethanol The femur bone was trimmed above and below the ends of the implant, cleaned of soft-tissue, and fixed in 70% alcohol The specimen was further ... developed intestinal obstruction after ingesting surgical dressing and was euthanized days before schedule The femora were harvested from this rabbit and included in the SEM analysis The details...
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Báo cáo y học: "Pre-clinical development as microbicide of zinc tetra-ascorbo-camphorate, a novel terpenoid derivative: Potent in vitro inhibitory activity against both R5- and X4-tropic HIV-1 strains without significant in vivo mucosal toxicity" docx
Ngày tải lên :
10/08/2014, 05:21
... Vaginal irritation index < 8: Acceptable; 9 10 : Marginal; and ≥ 11 : Unacceptable, according to Eckstein and colleagues (Eckstein et al., 19 69) and not into macrophages and DC, and decreased dramatically ... rabbit vaginal irritation model and helped draft the manuscript CC carried out the extraction and quantification of HIV -1 DNA and p24 ELISA BG and AM provided C14, participated in the Page of 11 (page ... HIV-1NDK and R5-tropic HIV-1Ba-L CC50a Antiviral molecules IC50b MΦ DC T cells MΦ* DC* T cells* C14 >10 >10 >10 HIV-1Ba-L 1. 3 ± 01 HIV-1NDK 0.02 ± 0.0 HIV-1Ba-L 1. 3 ± 0 .1 HIV-1NDK 1. 8 ± 0 .1 HIV-1Ba-L...
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báo cáo khoa học: " Osseointegration of zirconia implants compared with titanium: an in vivo study" ppsx
Ngày tải lên :
11/08/2014, 20:20
... period for both zirconia and titanium implants (Figure 5) After week of healing, the mean BIC was 35.3% ± 10 .8 for the zirconia and 47.7% ± 9 .1 for the titanium implants, respectively After weeks in ... (Masson-Trichrome-Goldner, 10 0-fold) were 71. 4% ± 17 .8 for the zirconia implants and 82.9% ± 10 .7 for the titanium implants There were no statistically significant differences observed betweeen the titanium and zirconia ... implant insertion into the maxillae of monkeys followed by months of loaded healing (68% for sandblasted zirconia implants and 73% for sandblasted and acid-etched titanium implants) However, the...
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Báo cáo y học: " Reproducibility of the airway response to an exercise protocol standardized for intensity, duration, and inspired air conditions, in subjects with symptoms suggestive of asthma" pdf
Ngày tải lên :
12/08/2014, 11:22
... FEV1 (L) Pack Yrs N =1 Ht (cm) Wt (kg) Mean 13 .0 21. 5 2.83 94.2 6.9 0.43 15 7.6 54.9 SD 3.0 4.3 0.92 12 .5 12 .8 16 .7 18 .2 Range 6 -17 13 .4-33 .1 1 .15 -5 .15 63.7 -12 7.4 0 -11 5 11 8 -19 2 20 -10 2 Median 14 21. 3 ... ventilation during the 2nd and 6th minute of the exercise with the highest fall in FEV1 was 57.3% ± 14 .5 and 53 .1% ± 12 .9 for adults and 54.6% ± 12 .9 and 51. 1% ± 11 .0 for the children The estimated ... FEV1 min -1 for the whole group and for adults and children separately are given in Table 3, together with mean and highest falls in FEV The variation for the response in all the adults and all the...
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Báo cáo y học: "Interleukin-18 as an in vivo mediator of monocyte recruitment in rodent models of rheumatoid arthritis" potx
Ngày tải lên :
12/08/2014, 14:22
... tissue MAA and CL assisted with arthritis induction and animal scoring of the ZIA model CL and HM performed the Western blotting, and CL and JHR performed the chemotaxis studies SS performed the ELISA ... Chicago, IL 60 611 , USA and 3Department of Internal Medicine, Ann Arbor Veteran's Administration, 2 215 Fuller Road, Ann Arbor, MI 4 810 9, USA 1Department 15 16 17 18 Received: 21 January 2 010 Revised: ... MS, Dinarello CA: Interleukin -18 (IFNgamma-inducing factor) induces IL-8 and IL-1beta via TNFalpha production from non-CD14+ human blood mononuclear cells J Clin Invest 19 98, 10 1: 711 -7 21 64 Thomassen...
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Báo cáo y học: " Cysteinyl-leukotrienes in the regulation of β2-adrenoceptor function: an in vitro model of asthma" ppsx
Ngày tải lên :
12/08/2014, 16:20
... 10 -7M MLK 10 -6M GFX 10 -7M GFX 10 -6M 5 72 ± 77 ± 10 2 ± 14 10 9 ± 11 6; 99 96 0.72 ± 0.04 0.73 ± 0 .11 0. 91 ± 0.05 0.84 ± 0 .15 0.96; 1. 23 1. 05 12 ± 12 ± 19 ± 14 ± 31; 10 Data are mean ± s.e.m or individual ... and 10 6M, n = 5), or GF109203X (10 -7M, n = and 10 -6M, n = 1) , or PSS (n = 6) for 30 and then challenged by a 60min incubation with 200 AU/ml of Dermatophagoides mix at 37°C Challenged rings incubated ... directly affected by LTD4 Relaxant responses to salbutamol in human bronchial rings The mean weight of the 24 bronchial rings was 91 ± mg The mean resting force and the mean normalizedresponse to carbachol...
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Báo cáo y học: "Tracing the HIV-1 subtype B mobility in Europe: a phylogeographic approach" doc
Ngày tải lên :
12/08/2014, 23:21
... (47%) 16 (18 %) (14 % (3%) 10 (11 %) (7%) (8%) 11 (13 %) (8%) 17 (19 %) (0%) (11 %) ( 21% ) 32 (36%) 19 ( 21% ) 15 (18 %) (19 %) 19 ( 21% ) 35 (39%) 16 (36%) 10 (11 %) 28 ( 31% ) (0%) (0%) (5%) (0%) (0%) (0%) (1% ) ... 77, 10 0, 10 3, 10 6 ,10 8, 11 5, 11 6, 15 1, 18 1, 18 4, 18 8, 19 0, 210 , 215 , 219 , 225, and 236) leaving 687 nt Phylogenetic analyses Sampling strategy For the estimation of country-wise clustering (migration), ... under panmixis – were detected from Italy to Austria and Switzerland, from Portugal to Luxembourg and also from the Netherlands to Germany (Table S2 in Additional file 1) On the other hand, Belgium,...
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Báo cáo y học: " Changes in the accessibility of the HIV-1 Integrase C-terminus in the presence of cellular proteins" doc
Ngày tải lên :
12/08/2014, 23:23
... for streptavidin binding after entry into the cell Biotinylation and capture of IN- BAD IN- BAD and IN- WT vector preparations were analysed by Western blot using anti -IN or anti-Biotin antibodies ... transducing units (Fig 1B) The kinetics of viral DNA synthesis (Fig 1C) and integration (Fig 1D) determined by PCR [17 ] over 72 hours following transduction were identical for IN- BAD and IN- WT ... the INQ168A-BAD and LEDGF/p75 in infected cells (293 INQ168A-BADv, Fig 4A lane 5) Another clear effect of the IN mutation was to render the IN C-terminus accessible for SA capture (Fig 4A, lane...
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Chemical modifications of DNA activate the cGAS STING signaling pathway even in the presence of the cytosolic exonuclease TREX1
Ngày tải lên :
26/11/2015, 10:17
... important for ligand recognition (Martin and Wesche, 2002), and an intracellular Toll/ interleukin1 receptor homology (TIR) domain, necessary for the recruitment of adapter proteins and intracellular ... IFNs initiate the Janus kinase (JAK)- signal transducer and activator of transcription (STAT) signaling pathway (Platanias, 2005) JAK1 and Tyrosine kinase (TYK2) bind to the activated IFNARs and ... the antibody can only bind to the binding sites of the specific target protein and not to unspecific binding sites of the membrane After blocking, the proteins of interest were labeled with an antibody...
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Tài liệu The wisdom of coaching: Essential papers in consulting psychology for a world of change pot
Ngày tải lên :
21/02/2014, 16:20
... relationship Establishing the working alliance Identifying and managing transferences Initiating and preserving containment Creating and managing expectations of coaching success Providing an experience ... performance Allenbaugh (19 83), Aurelio and Kennedy (19 91) , Bell (19 87), Bielous (19 94), Chiaramonte and Higgins (19 93), Cohen and Jaffee (19 82), Herring (19 89), Lucas (19 94), Rancourt (19 95), and ... control over the problems and issues Assessing, confronting, and solving problems and issues Identifying and working with emotions Identifying and managing resistance, defenses, and operating problems...
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The Project Gutenberg EBook of An Elementary Treatise on Fourier’s Series and Spherical, potx
Ngày tải lên :
15/03/2014, 00:20
... − 12 ; π 3π sin sin 12 12 sin DEVELOPMENT IN TRIGONOMETRIC SERIES 33 11 π π 33π 3π = π − , and = 3π − ; 12 12 12 12 but π sin π − 12 π sin 12 therefore 3π 12 3π sin 12 sin 3π − − = 1 − = 0, 2 and ... a1 sin = a1 sin 2π 4π + a2 sin 6π + a2 sin 8π + a2 sin 10 π + a2 sin + a2 sin 3π 6π + a3 sin 9π + a3 sin 12 π + a3 sin 15 π + a3 sin + a3 sin 4π 8π + a4 sin 12 π + a4 sin 16 π + a4 sin 20π + a4 sin ... for it V =√ M + x2 (1) c2 where M is the mass of the ring, and x the distance of the point from the centre of the ring Let us use spherical co¨rdinates, taking the centre of the ring as origin...
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Báo cáo khoa học: A study of microRNAs in silico and in vivo: bioimaging of microRNA biogenesis and regulation doc
Ngày tải lên :
16/03/2014, 01:20
... that the imaging of neuron-specific miRNA9 and miRNA9* can be important for understanding the functional role of miRNA during neurogenesis, and for investigating differences between miRNA and miRNA* ... collected and implanted (e.g into the thighs of a mouse) The expression level of the primiRNA transcript can be obtained from living animals by imaging the in vivo bioluminescence signals The optical ... detected in three cell lines using the Gaussia luciferase reporter vector containing three tandem repeat regions of miRNA23 binding sequence (reprinted with permission [11 ]) information for understanding...
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