the structure and electrical activity of neurons

... determining the structure of component organic compounds Testing of insecticidal and fungal activity of extracts and component organic compounds New contributions of the dissertation 3.1 For the first ... discusses the background, the scientific and practical significance, and the objectives of the research project Chapter Literature review 1.1 The fungi, insects harmful and the role of plant protection ... isolated and identified These are the first announcements about the genome of endogenous fungal strains on the Vietnamese C longa L and P betle L plants in Vietnam 30 Extracts of leaves and bark of the

Ngày tải lên: 09/01/2020, 14:59

... temperature? ?and? ?replacement ratio? ?of? ?Ni with Mn.   The? ?dependence? ?of? ?the? ?conductivity on? ?the? ?nickel substitution ratio? ?and? ?the? ?synthetic  temperature are shown in Fig.13? ?and? ?14.  The? ? calculation  results  of? ? the? ? lithium  ... increases with increase? ?of? ?the? ?annealing temperature? ?and? ?decreases with? ?the? ?increase? ?of? ?the? ? ratio? ?of? ?Ni.? ?The? ?values are between 8.21? ?and? ?8.24 Å.? ?The? ?ionic conductivity? ?of? ?the? ?materials  is strongly dependent on? ?the? ?substitution ratio? ?of? ?Ni molecules for Mn .The? ?sample has? ?the? ? ... because? ?the? ?concentrations? ?of? ?Mn3+? ?and? ?Mn4+ are equal in? ?the? ?material. Then F ( )  is clearly  distinguished by? ?the? ?substitution? ?of? ?Ni? ?and? ?the? ?sequence A1g becomes distinct? ?and? ?sharper  from? ?the? ?region F ( ) ? ?The? ?change in A1g? ?and? ?F

Ngày tải lên: 28/06/2021, 19:38

... energy of 30 eV and 15 eV for analysis of the regions and of 285 eV for calibration of the binding energies of the peak C 1s The atomic percentage of the elements present on the surface of the NPs ... in the reduction of the hydrodynamic diameter and the PDI of the NPs (Table 1) The reduction in the hydrodynamic diameter of the nanoparticles after addition of lecithin may be related to the ... encapsulation of the curcumin, an increase in the hydrodynamic diameter, the PDI and the zeta potential of the NPs was observed, as shown in Table This indicates the success in the encapsulation of the

Ngày tải lên: 07/01/2023, 21:27

... virtual orbitals of ANC and ANT is seen above –1 eV and is mainly composed of Al 3s atomic orbitals The valence band of the SANC appears in the region from –6 to –17 eV The new band below the original ... positions of openings from the ˚ with the interaction energy ( ∆ E Int ) of –23.8 kcal/mol, or adsorb the inside of the cage at a distance of 2.3 A top of the Al(I) site of openings at a distance of ... ANC and Al 50 O 75 ANT The observed bands at 1037 and 851 cm −1 are assigned to the stretching vibrations of Al–O bonds related to the openings and internal pore of the SANC, respectively The

Ngày tải lên: 12/01/2022, 23:54

... correct folding of the recombinant pro- teins, and the influence of N-glycosylation site occu- pancy in the structure of the proteins. SPR and PAGE studies confirm the ability of the nucleolin- derived ... 95%. Characterization of the glycosylation of recombinant proteins In order to check the occupancy of glycosylation sites and the structure of glycans, GC ⁄ MS, MALDI-TOF Fig. 1. Schematic structural ... of the recombinant nucleolin- derived proteins. Interference of N-glycosylation with the structure of the recombinant nucleolin-derived proteins The two minima observed at 210 and 222 nm in the CD

Ngày tải lên: 14/03/2014, 23:20

... to the termini of the module, which define the two apices of the some- what ellipsoidal protein. CCP structures are highly variable, with the invariant parts comprising mainly the b-strands. The ... FEBS under the conditions applied and therefore the constructs could be reliably used to assess the interde- pendence of the modules. This was corroborated by the calculated s c values of the tandem ... strands B and C, known as the ‘hypervariable loop‘, D and E, E and F, F and G, and G and H are particularly tolerant of longer insertions [19]. In multimodular proteins, however, insertions in the

Ngày tải lên: 15/03/2014, 23:20

... in vivo [22]. On the other hand, colocalization of VCP and PtdIns-4-kinase IIa on the buoyant subfraction of ER-derived mem- brane was observed [66]. The ND of VCP, rather than the D1 or D2 domains, ... are AAA- ATPases. Dysfunction of the ATPase activity of either of the two proteins results in peroxisome biogenesis disorders [4–7]. The ATPase activities of PEX1 and PEX6 are believed to be indispensable ... FEBS located at the end of the shallow groove between the N-lobe and C-lobe of PEX1-ND. An exposed constel- lation of hydrophobic residues is found along a longi- tudinal line of the kidney-shaped

Ngày tải lên: 16/03/2014, 12:20

... onto the dorsal surface and into the gut of the amphibian [1–4] A number of different types of bioactive peptides have been identified from the glandular skin secretions of Australian anurans of the ... reflect the poorly defined nature of the first turn of the a-helix due to the lack of hydrogen bonds to their NH protons Comparison of the observed NH chemical shifts of A4K14-citropin 1.1 with the ... to the frog as after about 10 of exposure on the skin a further endoprotease removes the first two residues of the peptide destroying the antibiotic (and anticancer) activity [9] The solution structure

Ngày tải lên: 17/03/2014, 09:20

... i. Because of the nested nature of the models (i.e., the model with con- straints on the slopes is a subset of the baseline model), the difference in the chi-square values for the baseline model and the ... groups. The next step examined the invariance of the variance–covariance matrix of the errors (⌰). Finally, the equivalence of the variances of the latent variables (⌽) was evaluated. The results of ... Studies 9 and 10, but in the former the 60–69 age group differed from the other two, whereas in the latter the oldest group differed from the others. Again, there was no pattern in either the items

Ngày tải lên: 22/03/2014, 11:20

... inwards, the arms close and the tips of the arms wrap around the DNA. The amplitudes and time scales of the intramolecular motions experienced by the protein backbone are com- monly determined from the 15 N-NMR ... composed of Leu8, His16, and Gly17, is present in seven structures, and another antiparallel b-bulge (B2), composed of Val57, Glu87, and Arg88, is observed for all the structures. The secondary structure ... rigid parts of MC1, such as the a-helix and the b-strands, excluding bulges. The correlation functions for two residues, Val18 in a bulge and Asn70 in the arm, are also shown. The fast decay of the Val18

Ngày tải lên: 22/03/2014, 17:20

... organization of the Cc RNase gene and its derived mRNA isoforms. The rectangles represent the exons and the horizon- tal bold lines the introns. The black parts of the rectangles show the protein-coding ... (SpuUn_WGA56223_2:75333–76952) and Nematostella vectensis (NW_001834409:c1450413–1449631). The numbers above the boxes indicate the size of the exons, and those below the lines indicate the size of the introns. ... (AAUAAA). The first signal (AAUAUA) is located just 19 bp upstream of the poly(A) tail of the shorter transcript and the second one is located 46 bp upstream of the poly(A) tail of the alternative transcript.

Ngày tải lên: 23/03/2014, 06:20

... However, the overall structures of aB-crystallin and HSP27 predicted by these two models are very similar, and the positions of the b-strands correlate well with the corresponding positions of the ... sHsp The primary structure of the a-crystallin domain of human sHsp is very conservative and the loop connecting the b5 and b7 strands is shorter than the corresponding loop connecting the b5 and ... and in the N-terminal part of the b7 strands destabilize the structure of HSP22 Limited trypsinolysis of the wild-type HSP22 and its K137E and K137,141E mutants Fig Far-UV CD spectra of the wild-type

Ngày tải lên: 23/03/2014, 07:20

... residues Tyr988 and Lys987 of the second molecule of the ‘dimer’ clash with the region where the adenosyl group of AdoMet is bound in the MetH structure. While the side chain of Lys987 can move ... domain and the FMN domain of MSR Titration of the activation domain of MS (both the D963E ⁄ K1071N mutant and wild-type proteins) with the FMN domain of human MSR resulted in a quenching of the ... versus the concentration of the activation domain and the curves show the best fit of the data to the quadratic Eqn (1). Table 3 lists the calculated dissociation constants for the wild-type and

Ngày tải lên: 23/03/2014, 09:21

... from the heme normal (z¢ axis), a is the angle between the projection of the tilt of the z axis on the x¢, y¢ plane (defined direction of tilt of z and the x¢ axis), and j % a + c defines the location ... ligated water molecule The two structures of WT metHb and rWT metHbH2O, exhibit significant differences in the interaction of the FG loop with the heme and in the position of the B-helix, with ˚ ... of WT and the other of rWT metHb, exhibit differences that include important portions of the protein that we have characterized above Thus parts of the FG corner move away from the heme and the

Ngày tải lên: 23/03/2014, 17:22

... Furthermore, the analysis of the calculated structures revealed a short distances between NH of Leu7 and the side chain carboxyl group of the Asp6 residue (< 0.28 nm), and NH of Leu7 residue and ... Characterization of the secondary structure of these two ligands of ODN receptors should provide useful information for the design of potent, stable and selective agonists and antagonists of these receptors ... ligands [13,14,27] The Ala-scan of OP has revealed that the side chain of each residue is required for the full activity of the peptide [12] These data led us to synthesize cyclic analogs of

Ngày tải lên: 24/03/2014, 04:21

... were to investigate the interactions between the KL 4 peptide and lipid bilayers, and the role of both the lipid composition and KL 4 structure on the surface adsorption activity of KL 4 -containing ... confocal microscopy of giant unilamellar vesicles (GUVs), (b) the effect of the lipid composition on KL 4 struc- ture, in the absence and presence of Ca 2+ , using CD and (c) the role of the lipid composition and ... would be in the fluid state. The T m of KL 4 -DPPC ⁄ POPG ⁄ PA (39.5 ± 0.1 °C) was quite similar to the T m of human lung surfactant in the presence of calcium and showed the end of the melting

Ngày tải lên: 30/03/2014, 11:20

... first introns and exons of Y1, Y2andY3. An alignment of the peptides predicted from the pleurocidin genes and pseudogenes is shown in Fig. 1. All of the genes, and even most of the pseudogenes, encode highly ... variants of this antimicrobial peptide family, predicted their sequences and determined the activity of synthetic peptides corresponding to these sequences against a variety of pathogens. With the ... genes and pseudogenes and determined the antimicrobial activities of synthetic peptides predicted from these sequences. We have performed a comprehensive survey of the differential expression of these

Ngày tải lên: 31/03/2014, 07:20

... Therefore, the structure of peptide cER consists of two b-turns, located at the N- and C-termini A comparison of the b-turn structure of cER with the similar region in the crystal structure of ... with the higher inhibitory activity of the cEL peptide and the very low inhibitory activity of the cYT peptide compared to other peptides The flanking residue of the b-turn, i.e Tyr3 of the cVY ... [38] Analysis of the crystal structure of CD2 revealed that on either side of the binding surface of CD2, there are b-turns which stabilize the b-strands Thus, we hypothesized that these b-turns...

Ngày tải lên: 19/02/2014, 13:20

... Fragments of HSQC and HMBC spectra of compound Labels illustrate assignment of the amide linkage between the amino group of Asp and the carboxyl group of GalA residue E Scheme The structures of oligosaccharides ... monosaccharides present in the products and were identified, and the ratio of structures and was close to : All chemical shifts remained mostly unchanged with the exception of H/C-2 and H/C-3 of the glycerol ... because of the existence of branches in the molecule Similarly, the tandem MS was conducted for the doubly charged ion at m/z 1180.25 (data not shown) and the mass spectral data fully agree with the...

Ngày tải lên: 19/02/2014, 16:20

... estimate the fair value at the grant date of the equity instruments” (FAS An alternative way to measure accuracy is the standard deviation of the difference between the reported value and the benchmark ... time-specific Thus, the amount of reporting flexibility and the ease of auditing may differ across the inputs I discuss these differences when interpreting the results of the reliability analysis ... in the contractual length and moneyness of options On average, mandatory recognizers reduced the contractual length of CEO and executive options by 3.5 and 2.5 months (significant at the 5% and...

Ngày tải lên: 03/06/2014, 01:05