the role of viral integration in the development of cervical cancer

Ngày tải lên: 14/08/2014, 14:21

Ngày tải lên: 07/08/2014, 14:23

... cost-effective way of as- sessing health risks; the identification of all risk points along the chain of events from the origin of the wastewater to the consumption of the produce (e.g. the farm-to-fork ... Ho- epner,2008). There is scope to improve the sustainability of the desalination process. The process results in the discharge of a concentrated brine into the receiving waters. Temperature and salinity ... approach of the HAPPC meth- od in food safety); the design of a combination of health risk management mea- sures, to be applied along the same chain of events, with the aim of ensuring health...

Ngày tải lên: 17/02/2014, 10:20

Ngày tải lên: 17/03/2014, 07:20

Ngày tải lên: 29/03/2014, 22:21

Ngày tải lên: 10/08/2014, 09:22

Ngày tải lên: 12/08/2014, 04:20

Ngày tải lên: 14/08/2014, 08:20

... Secondly, Linh Dam New Town (located in the south-west of Hanoi) deserves one of the new urban models, dealing with the high-density development in the south-west of Hanoi. By learning from the ... landscape in the south gateway of the capital city (HUD). 3.2.2. Uses and Activities Linh Dam project is one of the successful models of the development of high-rise apartment buildings. The development ... quarters, the last one is the central area for the purpose of resettlement. Generally, getting along with the rapid expansion, the east bank of the Red River exhibited the beginnings of urbanization....

Ngày tải lên: 29/08/2013, 08:15

... jobs as family care, selling goods in the streets or in- waiting labor markets. Although working time is rather long (11- 13 hours/day) and continuously, their montly income average only ranges ... labors selling goods in the streets and in- waiting labor market have to work in unsafe environments; their daily life are rather poor. 22.86% female freelane labors live in boarding houses characterized ... factors (living and working environments in cities, home-town customs, working conditions and relating policies) were identified as the determinants affecting to jobs and daily life of female...

Ngày tải lên: 29/08/2013, 08:15

... under the framework of financial globalization. II. Review of Institution Building in the Financial Sector A. Main driving forces of institution building A review of the developments of China’s financial ... source of financing for enterprises, if their own capital is excluded. In summary, the deepening process of the financial markets has rendered the dominance of the banking sector in the financial ... forceful in improving microeconomic performance. 2. Role of the central bank The central bank has played a role of policy designing and implementation in the process of institution building in the financial...

Ngày tải lên: 18/10/2013, 07:15

... ( 39 ). The renewed interest in examining the indications for BCG vaccination in the United States included consideration of the wide range of vaccine efficacies deter- mined by clinical trials ... to explore the sources of the heterogeneity in the efficacy of the BCG vaccine reported in the individual studies. Using a model that included the geographic latitude of the study site and the data ... <5 mm induration after skin testing with 5 TU of PPD tuberculin. The Tice strain of BCG is administered percutaneously; 0.3 mL of the reconstituted vaccine is usually placed on the skin in the lower...

Ngày tải lên: 15/02/2014, 13:20

... an important role in the financial system of the U.S. economy. They complement the role of large banks by special- izing in relationship banking and providing credit to small businesses—a sector ... “Small Business Lending and the Changing Structure of the Banking Industry,” Journal of Banking and Finance, August. Sullivan, Richard J. 2000. “How Has the Adoption of Internet Banking Affected Performance ... understanding issues facing community banks. I. THE CURRENT ROLE OF COMMUNITY BANKS The banking system in the United States has always been unique in the sense of containing large numbers of small...

Ngày tải lên: 16/02/2014, 11:20

... or without hematoxylin staining. In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O 2 . Culture medium ... lgÆmL )1 insulin, 1 lm dexamethasone, and 0.5 mm IDM). Cells were then maintained in DMEM con- taining 10% fetal bovine serum and 1 lgÆmL )1 insulin. The medium was replaced every other day. ... cultured in DMEM containing 10% fetal bovine serum. OP9 cells were grown in aMEM containing 20% fetal bovine serum. C2C12 cells were maintained in DMEM containing 10% fetal bovine serum. Adipogenic...

Ngày tải lên: 18/02/2014, 08:20

... detected at the dimer interface of the models or in the surroundings of the mutated residues. The models of RNase A covalent dimers in the exchanging conformation were prepared using the 7RSA structure ... at the dimer interface of the models or in the surroundings of the hinge loop residues. Likewise, the models of nonex- changing and exchanging HHP-RNase were prepared start- ing from 1Z7X. The ... through the exchange between subunits of either their N-ter- minal, or their C-terminal ends [33–35]. We found that the behavior with the model membrane of the dimer in which the C-terminal ends...

Ngày tải lên: 19/02/2014, 06:20

... N-linked oligosaccharide side-chains are important for the GABA transport activity. 1-Deoxymannojirimycin inhibits the GABA-uptake of GAT1 In order to gain further insight into the role of the terminal ... results in reduction of the stability of GAT1 In order to study the in uence of the N-glycosylation and N-linked oligosaccharides on protein stability, the intracellular decay time of the GAT1, ... for the stability of this protein, but the terminal structure of the N-glycans is not. Defective N-glycosylation reduces the trafficking of GAT1 to the plasma membrane In order to study the in uence...

Ngày tải lên: 19/02/2014, 17:20

... thus blocking protein synthesis and leading cells to death. The current model proposed for the mechanism of antitumour action of BS-RNase is based on the ability of the protein to resist the neutralizing ... plateau. These data indicate that the cell sulfhydryls responsible for the exchange with the protein disulfides are located in the plasma membrane. Furthermore, they show that, as proposed in the hypothesis ... hypothesize that the cytotoxic activity of the latter monomers was due to the presence in these proteins of disulfide bonds, with their potential chemical instability. It is well known that in the...

Ngày tải lên: 20/02/2014, 11:20

... However, the mechanistic roles of several of these residues are not described well and there is no example of mutational analysis of all of these residues in the same enzyme. To obtain an insight into ... by the surrounding residues. The results so far indicate that larger parts of the polar core of the catalytic TIM barrel of family 18 chitinases play a role during catalysis. It will thus be interesting ... conformations. The Asp142 equiv- alent in the family 18 chitinase from Coccidioides immitis was found to be in the ÔdownÕ position in the apoenzyme and in the ÔupÕ position in the complex with allosamidin...

Ngày tải lên: 07/03/2014, 14:20

... a donor of propylamine groups in the metabolism of spermidine and spermine [2] and an intermediary in the trans-sulfuration pathway to cysteine, one of the three amino acids involved in glutathi- one ... to determine the functional role of the amino acid residues involved in each. The present report describes the cloning and subsequent functional refolding, using a bacterial expression system, of the ... domain of each subunit, in the interface between the two dimers compri- sing the tetrameric structure [29]. This domain contains five cysteine residues, two of them (Cys35 and Cys61) forming a...

Ngày tải lên: 08/03/2014, 08:20

... is the shift of the pH optimum from near neutral in the wild-type to pH 9.2 in the R389A mutant, which is in accord with an increase in the pK of Y229 if the stabilizing R389 residue is lacking. ... coordination to the other ligands of the binding site (center I), but the binding becomes much weaker as emphasized by the dramatic increase of the Na + ion concentration required to saturate the enzyme. ... carboxybiotin, or slow Na + move- ment through the channel to its binding site. Following the decarboxylation of carboxybiotin in the reaction cycle (Fig. 4B,C), the biotin prosthetic group leaves the...

Ngày tải lên: 08/03/2014, 23:20