... 0.36) Similar patterns were seen both in controls and in cases Possible associations of AD with HLA-B & C alleles Tables and show the overall results for the 26 studied alleles Apart from the associations ... EM: Clinical diagnosis of Alzheimer' s disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services task force on Alzheimer' s disease Neurology 1984, ... view of the consistency between the results of the two studies, we pooled the two datasets for further analysis of HLA-B7 and HLACw*0702 Possible interactions of HLA-B7 and HLA-Cw*0702 with other...
Ngày tải lên: 19/06/2014, 22:20
... proteins are produced in the human brain, but less is known about their CNS synthesis in other species [31] The status of some of these regulatory proteins in AD is unclear; for example, there ... models of human disease generally have similar pathological findings to the human disorders, distinct differences remain These models may be appropriate for studying some aspects of a disease process, ... appears to be the most promising primate species to date for studying the significance of ADrelated complement activation because of the presence of NFTs as well as plaques Other animal species Scattered...
Ngày tải lên: 19/06/2014, 22:20
List of non-governmental organizations in consultative status with the Economic and Social Council ppt
... (2005) International Association of Jewish Lawyers and Jurists (1995) International Association of Judges (1985) International Association of Lawyers against Nuclear Arms (1995) International Association ... All-Russian Social Fund The Russian Children Foundation” (2003) All-Russian Society of Disabled People (1998) All-Russian Society of the Deaf/All-Russian Public Organization of Persons with Disabilities ... Association of Penal Law (1948) International Association of Ports and Harbors (1966) International Association of Prosecutors (2001) International Association of Schools of Social Work (1947) International...
Ngày tải lên: 23/03/2014, 21:20
báo cáo hóa học: " The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer''''s disease" ppt
... patients with the rare recessive genetic disorder, chronic granulomatous disease (CGD) This disease is characterized by a mutation in the genes that encode one of the essential subunits of the NADPH ... kinases Lyn and Fyn as well as the tyrosine kinase Syk [30,32,52] Activation of these signaling cascades are linked to the synthesis and secretion of proinflammatory molecules and cytokines [28,30,52-58] ... astrocytes results in their extensive exposure to Aβ from the earliest stages of the disease Indeed, reactive astrocytes are found adjacent to senile plaques Plaque-associated astrocytes upregulate the...
Ngày tải lên: 19/06/2014, 22:20
Báo cáo khoa học: "the Role of Non-Timber Forest Products (NTFPs) in Livelihood Strategies and Household Economies in a Remote Upland Village in the Upper Ca River Basin, Nghe An, Vietnam" pdf
... They include fruits, nuts, vegetables, fish and game, medicinal plants, resins, essences, and a range of barks and fibers such as bamboo, rattans, and a host of other palms and grasses” NTFPs ... Discussions From these results, we can see the livelihood strategies pursued within the village, the trend of household economic development, and the roles of NTFPs in the livelihood strategies ... cash income) was not included in this analysis because it is an outlier It is considered in the discussion section 92 The Role of Non- Timber Forest Products (NTFPs) in Livelihood Strategies since...
Ngày tải lên: 06/08/2014, 19:20
Social participation in education and the role of non-public universities in meeting diversified needs of socio-economic development
Ngày tải lên: 11/03/2015, 08:00
The role of solitude in paul auster s prose
... to the story of Pinocchio and his 19 father, imprisoned in a belly of a shark He describes these stories as metaphors, as reflections of situations similar to his own life Auster understands the ... to express his emotions and feelings that his son cannot understand so far Through the process of writing The Book of Memory, Auster s son Daniel got seriously ill His diagnosis was a severe pneumonia ... arbitrariness of Stillman s actions He wanted there to be a sense to them, no matter how obscure” (Auster, The New York Trilogy 69) If the case is meaningless, then Quinn s new identity loses its sense...
Ngày tải lên: 14/04/2016, 18:03
báo cáo hóa học: " Psychometric validation of the revised SCOPADiary Card: expanding the measurement of nonmotor symptoms in parkinson’s disease" potx
... duration) Scale scores were compared across these groups and statistical significance was assessed using the independent samples t-test if the scores were normally distributed and the Mann-Whitney test ... fills an important gap in the assessment of PD symptoms Conclusions The results of the current study provided preliminary evidence of the domain structure of the Revised SCOPA-DC Although use of ... measuring the impact of PD symptoms and the severity of off-time Longitudinal studies that allow for the assessment of specific properties such as test-retest reliability and responsiveness will...
Ngày tải lên: 20/06/2014, 15:20
Báo cáo y học: "Cytokines in the colon of a patient with Behçet’s disease" ppt
... chromosomal breakpoints impact the level of LMO2 expression in T-ALL Blood 2007, 110:388-392 Yazici H, Fresko I, Yurdakul S: Behçet s syndrome: disease manifestations, management, and advances in ... Missotten T, van Daele PL, Jamnitski A, Baarsma GS, van Hagen PM: Adalimumab: a new modality for Behçet s disease? Ann Rheum Dis 2007, 66:565-566 Page of (page number not for citation purposes) ... Arthritis Research & Therapy Vol 11 No Kappen et al in colonic tissue of a BD patient, IFN-γ, TNF-α, and IL-17A appear to be key cytokines, even in a treated patient Competing interests The authors...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Th2 cytokines and asthma The role of interleukin-5 in allergic eosinophilic disease" doc
... development of allergen-induced airway hyperresponsiveness to substance P It also inhibited the accumulation of total cells, eosinophils, and neutrophils in the lungs of guinea pigs A rising single-dose ... mediating synthesis of interleukin-1β in airway smooth muscle [72] review In the human, interleukin-5 is selective for eosinophils and basophils, whereas in the mouse it also acts on B lymphocytes [3,7,50] ... Because the activity of interleukin-5 is restricted to eosinophils, it should be an ideal target to block this response in the lungs of allergic animal models of asthma, and has been studied in several...
Ngày tải lên: 12/08/2014, 18:20
operation of american non-governmental organizations in the first decade of the twenty-first century in danang
... in Danang” as a Master s thesis in the field of International Relations Subjective of Study From the above mentioned reasons, this study is intended to focus on activities of only international ... in the near future Research Questions Based on the above aims and objectives, this study will be the answers to the following research questions: - What is the current status of operation of ... addition, this study is to discuss operation of international American NGOs in Danang and their impacts of projects implemented in the early years of the twenty-first century Also, this study is about...
Ngày tải lên: 10/10/2014, 10:51
Perfecting the content of state management for international non governmental organizations in Hanoi nowadays
... INGOs of Hanoi city on the basis of assignment of specific common tasks of working group and tasks of the members of the working group 3.3.7 Inspection and supervision Inspection and supervision ... laws and regulations of the State; and inspecting and supervising the effectiveness of INGOs aid On the other hand, inspecting and supervising are 23 also to ensure that the activities of these ... apparatus system fully and competently The State must reassess existing management apparatus, review to determine the surpluses, the deficits of the current system Have to build an apparatus from the...
Ngày tải lên: 06/11/2016, 15:21
Tài liệu The Role of Nutrition in Maintaining Health in the Nation’s Elderly: Evaluating Coverage of Nutrition Services for the Medicare Population ppt
... settings of care Each of the conditionspecific chapters addresses the strength of the evidence for the efficacy of the role of nutrition, makes recommendations regarding the provision of services ... its workshop and public meeting Workshop speakers included Bess Dawson-Hughes, MD and Ernest Schaefer, MD of Tufts University, Boston; Linda Delahanty, MS, RD of the Massachussets General Hospital, ... policy and its statutory limitations For the purposes of this report, the committee considered the term “nutrition services” to consist of two tiers The first tier of services is basic nutrition...
Ngày tải lên: 15/02/2014, 16:20
Tài liệu The Role of Community Banks in the U.S. Economy pdf
... percent of bank assets The reason community banks hold a smaller share of bank assets and loans than of bank deposits is that they have less access than larger banks to nondeposit sources of funds such ... smaller customers such as small businesses, family farmers, and depositors of low to moderate wealth Small business lending Community banks’ role as small business lenders is important because ... bifurcated banking system has served the needs of a diverse U .S economy composed of businesses of all shapes and sizes and consumers with diverse needs and preferences While community banks have a clear...
Ngày tải lên: 16/02/2014, 11:20
Tài liệu Egypt''''s Water Warriors : Water Pollution in Egypt and the Role of NGOs in Reaching Integrated Management ppt
... service especially in rural areas (7% at most) makes nearby streams (either canals or drains) the perfect places for inhabitants to dispose their sewage as in the case of Ezbet El-Eslah The fresh water ... facilities The use of fertilizers and pesticides has significantly increased after the construction of High Dam and causes weed flourishing, which increases evapotrans piration, blocks the waterways, ... pollution2 sources in Egypt today are various and Industrial wastes are considered3 the major source On the other hand, about 90% of the rural populations have no access to sewer systems or wastewater...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu Báo cáo khoa học: A facile method for expression and purification of the Alzheimer’s disease-associated amyloid b-peptide pdf
... since the sequence of Ab was first determined, high-resolution structural analysis of Ab monomer and its assemblies has been hampered because of the lack of an affordable source of Ab peptides ... at least as pure as the synthetic peptides purified by reverse-phase HPLC, a finding corroborated by LC-MS analysis (Figs and S2 ) The fibril-forming properties of Ab peptides were assessed using ... neurons (Fig 7C), with a similar loss evident for all peptides Discussion Because extensive evidence supports a crucial role for Ab in Alzheimer s disease pathogenesis, there is huge interest in...
Ngày tải lên: 18/02/2014, 13:20
PET in the Evaluation of Alzheimer’s Disease and Related Disorders docx
... abnormality The first element of a mental status test should be the assessment of the patient s level of awareness, because awareness affects the rest of the evaluation Note if the patient is alert, ... Parkinson s disease than in DLB The diagnosis is supported by a history of syncope, falls, confusion, extreme sensitivity to the movement side effects of neuroleptics, delusions, and other types of ... 18 DeKosky S Early intervention is key to successful management of Alzheimer disease Alzheimer Dis Assoc Disord 2003;17(Suppl 4) :S9 9–104 19 Leifer BP Early diagnosis of Alzheimer s disease: clinical...
Ngày tải lên: 05/03/2014, 23:20
Enterprise Adjustment and the Role of Bank Credit in Russia: Evidence from a 420 Firm''''s Qualitative Survey pdf
... large, the main conclusions of the paper provide ground for a rather pessimistic assessment of the adjustment performances of Russian enterprises in 1996 Profit appears as a function of the capacity ... internal consistency of the data base as well as a series of relationships between the different variables, including profit This also makes possible the identification of four sub-groups of firms, with ... of Russian industrial enterprises, in relationship with the constraints they are facing and the adjustment strategies they show We focus on their relationship with banks, because of its strategic...
Ngày tải lên: 06/03/2014, 08:20
Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx
... but their development is the result of an aberrant shift in activity of tau kinases and phosphatases [3] Thus, although targeting plaques and NFTs may ameliorate some of the consequences of AD ... causes decreased activity of critical enzymes because activity of the enzymes is dependent on optimal metal loading Cu deficiency is central to the recessive Menkes and Wilson diseases, and has ... metal deficiency by sequestering metals outside the cell Figure summarizes these interdependent dysfunctional events With the loss of biometal homeostasis placed central to all of these AD-related...
Ngày tải lên: 07/03/2014, 10:20
The Handbook of Alzheimer’s Disease and Other Dementias doc
... treating Alzheimer s disease In 1984, the first clinical criteria for the diagnosis of Alzheimer s disease was published, and the first five Alzheimer s Disease Research Centers were established with ... improved the diagnosis of dementia syndromes; in turn, the study of neurodegenerative diseases has helped boost neuropsychological research Neuroimaging also helps distinguish Alzheimer s disease, ... areas of Alzheimer s disease and dementia will find this book of interest, including physicians, medical students, psychologists, scientists, graduate students, and allied health professionals including...
Ngày tải lên: 14/03/2014, 21:20