the role of energy metabolism in the human body

... INVESTIGATING THE ROLE OF MENAQUINONE METABOLISM IN DORMANT MYCOBACTERIA BY ANTISENSE RNA THOMAS M FIEDLER NATIONAL UNIVERSITY OF SINAGPORE 2007 Investigating the role of menaquinone metabolism ... synthesis during dormancy and its... focusing on the involved enzymes The focus of this study lies on the synthesis of the aromatic portion of menaquinone The synthesis of the ... contain approximately a 100 bp part of the upstream region of each gene including the Shine-Dalgarno site and about a third of the coding region of the genes of interest The

Ngày tải lên: 08/11/2015, 16:46

... residues for binding the coenzyme The C-terminal domain has a largely a-helical structure, and serves mainly in substrate binding The active site is located in the interdomain cleft, and contains a highly ... mm), and so the choice of the constant level of Fru was not critical for determination of DKm (1.23 ± 0.15) The KIE data in Table are instrumental in delineating the kinetic mechanism of AfM1PDH ... value of $ 3, indicates that NADH binds to the enzyme prior to binding of Fru6P The absence of a KIE on kcat ⁄ Km for the substrate binding first is a clear requirement of the strictly ordered kinetic

Ngày tải lên: 14/03/2014, 23:20

... addressed. The report builds on extensive previous and on-going work of the OECD in the area of „green growth’. 3 The focus is on the role of institutional investors, again building on OECD work in ... institutional investors are offered appropriately structured financing vehicles. In order to achieve the goal of encouraging further investment in clean energy projects by institutional investors, ... to energy plays a crucial role in securing human well being. For the purpose of this report, clean energy refers to the BNEF definition which includes bio energy, geothermal, hydro, marine,

Ngày tải lên: 30/03/2014, 12:20

... occurring with regards to the binding of UK4V L to CL. The effect of point mutations of specific arginine residues in CDR3 of IS4V H upon CL binding is shown in Fig. 4. The low binding of IS4V ... the numbers of arginine residues in the CDRs of these antibodies can lead to significant alterations in bind- ing to DNA. Arginines in V H CDR3 often play a particularly important role in binding ... arginine residues in IS4V H As reported previously, the presence of the heavy chain of IS4 plays a dominant role in binding to CL [29]. IS4V H binds CL in combination with six of the 10 light chains

Ngày tải lên: 09/08/2014, 06:22

... result in an increase in the gene expression of the aggrecanase ADAMTS4 in cells derived from degenerate NP In vivo, the NP contains the highest concentration of aggrecan in the IVD The response of ... observed on the other cell types (Fig 6d) Discussion In this study, we investigated whether in IVD degeneration there is local production of the cytokine IL-1 and whether IL-1 could induce the cellular ... MMP-13 protein is present in significant amounts in IVDs, with the highest immunopositivity in the NP of degenerate discs [6], an area of the IVD containing the highest concentration of collagen

Ngày tải lên: 09/08/2014, 06:22

... of the role of PrP in breast cancer metabolism in the study model Picture showing different lactate production in normal and cancer situation Schematic overview of the role of PrP in cancer metabolism ... including the no-protein control. The values for the protein standards were plotted with a linear regression line through the standard points. The protein concentrations of the samples were then calculated ... differences in the role played by PrP in different cancer cells. However, closer scrutiny of our results show a trend of increasing expression of PrP correlating with increasing metastasis profile of the

Ngày tải lên: 12/10/2015, 17:36

... role in raising the profile of women in management It will also discuss how the current findings on leadership are likely to impact on the career advancement of women in leadership roles in the ... raising the profile of women in management However, during this period of research, there was an emerging recognition of the importance of a concern for people in the behavioural theories as being ... anything towards raising the profile of women in management, as the theory was constructed as a male model at a time when women were not visible in paid employment One of the off shoots of the

Ngày tải lên: 08/10/2013, 15:56

... used for seeing The meaning I ( called the first meaning ) presents the centre of the semantic structure of the word holding it together. It dominates over the other meanings. The meaning II, III ... 1.3. Names of part of the human body with the transference of meaning and cultural symbolism. 12 Chapter 2. The contrastive analysis of class of words denoting parts of the human body in English ... only study the polysemantic words having primary meaning denoting parts of the human body. We do not pay attention to words having derived meaning denoting parts of the human body and to the phenomenon

Ngày tải lên: 18/12/2013, 21:45

... asp?getitem=685) Marine pollution Direct or indirect introduction by humans of substances or energy into the marine environment (including estuaries), resulting in harm to living resources, hazards to human ... THINKING TO THE LONG TERM Innovative financing of appropriate wastewater infrastructure should incorporate design, construction, operation, maintenance, upgrading and/or decommissioning Financing ... beneath the earth’s surface (usually in aquifers) supplying wells and springs Because groundwater is a major source of drinking water, there is a growing concern over leaching of agricultural and industrial

Ngày tải lên: 17/02/2014, 10:20

... sedoheptulose- 1,7-bisphosphatase. Discussion One of the original goals motivating this structural inves- tigation of the Calvin cycle was to determine whether or not the traditional reactions of the Calvin cycle are capable of sustaining ... modelling stem primarily from the uncertainty in the definition of the kinetics, both in terms of the form that the rate equation should take, and in the values to be assigned to the associated kinetic ... as being some combination of the following: (a) production of redox potential in the form of NADPH; (b) production of glycolytic intermediates, reducing the demand put upon phosphofructokinase;

Ngày tải lên: 20/02/2014, 23:20

... difficulties in servicing their existing... most of them and access-to-input for the worst in this sub-pool Conversely, the overbearing influence of the financial constraints in the ... evolution of the same type of variables; their judgement on their actual and future behavior, including the type of constraints they face. Some sets of answers are strongly cardinal, as for the current ... including a higher probability of posting profits. Lastly, the evolution of credit over the preceding six months (on the basis of 100 index) provides a measure of the actual distribution of bank

Ngày tải lên: 06/03/2014, 08:20

... outreach continues to grow in terms of the number of microborrowers Institutions providing microfinance in Asia play a critical role in increasing the access to finance for underprivileged ... providing financial services to underserved markets distinguishes them from most other formal financial institutions In addition to the distribution of part of their profits for increasing ... MICROCREDIT: THE ROLE OF SAVINGS BANKS IN MICROFINANCE Experiences from Latin America, Africa and Asia PERSPECTIVES 59 July 2009 BEYOND MICROCREDIT: THE ROLE OF SAVINGS BANKS IN MICROFINANCE Experiences

Ngày tải lên: 06/03/2014, 10:20

... of the series is to get the findings out quickly, even if the presentations are less than fully polished. The papers carry the names of the authors and should be cited accordingly. The findings, ... use – in determining individual earnings, and by implication important aspects of the income distribution. We then turn to the relationship of education and economic growth. Research into the ... within the current structure and institutions of schools, but the findings do not put resource discussions into the context of alternative structures. One consistent finding that is emerging

Ngày tải lên: 08/03/2014, 08:20

... as Points of Access into the Financial System The Role of African Post Offices in Payments The Role of Post Offices in International Remittances The Role of Post Offices in Savings The Role of ... On the other hand, in the course of the desk research in 2004, other countries that were not included in the list of 24 countries were found to have postal networks with an active role in financial ... offices were seen as an “anchor” in the mail-processing infrastructure In many of the countries in the MNA region, this has remained the case In few countries, separate (automated) mail sorting

Ngày tải lên: 15/03/2014, 10:20

... Further examples are presented from the US including the Tar-Pamlico Basin in North Carolina (case of point-point source trading also allowing for point-non-point trade), the case of ... number of other on going and... with the inter-state trading case in the Murray-Darling Basin, and the more market-oriented approach in the Hunter River in the State of New South ... trading came into force in 1992 as part of the Murray-Darling Basin... due to the difficulties in addressing non-point source pollution The difficulties in controlling non-point

Ngày tải lên: 15/03/2014, 16:20

... trees. The largest plant height was obtained using linings of stone and marble. During the first year of the study, when the lining served only as mulch due to lack of rainfall, an increase of ... to improve the HI of wheat, 9 The harvest index is defined as the ratio of grain to total crop biomass” (Cassman 1999). The Role of Rainfed Agriculture in the Future of Global Food ... Considerations of risk may be very important in the initial decision of whether to adopt rainwater harvesting at an individual farm level. Especially due to the low economic status of many of the farmers...

Ngày tải lên: 09/03/2014, 00:20

... to the banking sector The previous subsection analyzes how the banking sector, through the dynamics of bank capital, affects the transmission of shocks. In recent years, however, episodes of increased volatility ... to them. In this context, this subsection considers the effects of a shock that arises in the banking sector of our model and leads to exogenous declines in bank net worth. Following the theoretical ... households investing in the bank is limited by the two moral hazard problems: if either were to worsen, the payment to households would decrease. Introducing (19) into the participation constraint (14),...

Ngày tải lên: 15/03/2014, 10:20

... IPv6. In other words, once the cost of deploying IPv4 infrastructure – determined by the cost of obtaining the addresses themselves and the cost of designing and operating networks that use fewer ... forward them to the next physical network. IP addresses play a fundamental role in the functioning of the Internet. They identify (―who‖ role) participating devices on the network of networks ... DSTI/ICCP(2007)20/FINAL 3 TABLE OF CONTENTS FOREWORD 2 MAIN POINTS 4 INTRODUCTION 7 I. AN OVERVIEW OF INTERNET ADDRESSING 12 Overview of major initiatives in Internet addressing and routing to-date...

Ngày tải lên: 06/03/2014, 21:20

... research so the input of Australian staff in the actual training program of TOT was minimal and did not warrant inclusion in the cost of the training. GAP Workshop in Binh Thuan (21-22/7/2008) ... not know the origin of their planting material. In both regions the use of mineral fertilisers was very high, with 95% of farmers reporting their use in the MD and 88% in the CC. Use of organic ... profit. It is fair to assume that just the saving in the cost of pesticide as a result of reduction in the number of sprays was higher than the investment made in FFS. Note: 1 During the...

Ngày tải lên: 21/06/2014, 05:20

... form the NADP + -bound enzyme. The extent of the red- shift following the addition of different concentrations of NADPH was then used to estimate the efficiency of NADPH binding. The results of these ... step is involved in pigment loading. The precise role of any possible POR kinase therefore still remains unclear. The main line of evidence for the existence of a POR- phosphatase is the observation ... PChlide in this system. The results of measurements of the effects of ATP, ADP, AMP and adenosine on the corresponding low pH-induced blue-shift in the absorption maximum of maize PLB, made in the...

Ngày tải lên: 22/02/2014, 04:20