... the music projects the meaning ofthe image or the image projects the meaning ofthe music), then the multimedia example has passed the similarity test andthe relationship exhibited is one of ... music), taking into account the director’s – and, therefore, the composer’s – intentions, the narrative content ofthe film, andthe overall strategy ofthe director in constructing the multifaceted ... other-worldly In this capacity, theroleof music is significantly enhanced by the level of ambiguity inherent inthe visual scene Specifically, the more ambiguous the meaning ofthe visual image, the...
... privileging ofthe site of caretaking as the locus of producing and reproducing male domination and female subordination Chodorow, it is argued, was guilty of generalising inappropriately andof not ... required inthecontextof recognising them as explicitly gendered Finally, feminist, gay and other critical scholarships offer crucial insights in understanding men and masculinities A note of caution, ... whatever the merits and demerits of particular analyses that engage with it, the worth of psychoanalysis in understanding masculinity lies in its help in grasping the structuring of personality and the...
... the reader to gain: • An understanding ofthe structures ofhealthandsocialcareinthe UK • An insight into why healthandsocialcare changes • An understanding ofthe impact of changes in ... focus and priority within their daily practice in other settings The contextofhealthandsocialcare Figure 1.2 Structures inhealthandsocialcare These structures are in a constant state of ... assist in understanding complexity and inform complex problem solving Inthecontextofhealthandsocial care, a basic appreciation of systems-thinking and concepts can help understanding of, for...
... the domains and sub-domains Furthermore, the sub-domains were correlated with the domains andthe total score, andthe domains were correlated with the total score The items/sub-domains/domains ... data from clinical trials studying atomoxetine and using the CHIP-CE inthe Lilly data base were included The total number of patients included inthe combined analysis was 794 Three of these studies ... between the sub-domains andthe domains and between the domains andthe total score at baseline, at endpoint after the placebo-controlled period, and for the change from baseline to that endpoint...
... useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy ofthe vaccine strain administered Vol 45 / No RR-4 MMWR andthe vaccinee’s age at the time of vaccination ... Control and Prevention Theroleof BCG vaccine inthe prevention and control of tuberculosis inthe United States: a joint statement by the Advisory Council for the Elimination of Tuberculosis andthe ... million vaccinees in Sweden and Finland, respectively (46 ) Regional increases inthe incidence of BCG osteitis have been noted following changes in either the vaccine strain or the method TABLE...
... N-linked oligosaccharide side-chains are important for the GABA transport activity 1-Deoxymannojirimycin inhibits the GABA-uptake of GAT1 In order to gain further insight into theroleofthe ... modification may in uence many ofthe physicochemical and biological properties ofthe proteins, such as protein folding, stability, targeting, dynamics and ligand binding, as well as cell-matrix and cell–cell ... misfolding of this protein, resulting in its partial retention inthe ER and its rapid digestion thereafter [16,19] Accordingly, our results indicate that the intracellular trafficking of N-glycosylation...
... the left to the right-hand side ofthe map decreases the probability of Expected-Debt to be equal to ô ằ (increase in indebtedness) by 15 points (33 minus 18), and increases the probability of ... Survey In 1996, the credit has overall been decreasing for 53% ofthe sample, it has been increasing for 36%, and has been stable for the remaining 11% An increase in indebtedness (of 80% in average) ... constraints The descriptive, statistical analysis in Table indeed confirms that the lower the decline in production (or the higher its increase, inthe best cases), the higher the probability of...
... However, the mechanistic roles of several of these residues are not described well and there is no example of mutational analysis of all of these residues inthe same enzyme To obtain an insight into ... inthe ÔupÕ position rows and shows that inthe presence ofthe substrate, rotation of Asp142 towards Glu144 lowers the pKa ofthe latter by 0.8 pH units The calculated effects ofthe D140N and ... affinity of ChiB for allosamidin, which is an analogue ofthe proposed oxazolinium ion intermediate [32] The minor (or even positive) effects of Y214F on substrate and intermediate binding and the...
... Stereo figures ofthe model ofthe bound substrate inthe AD2 E526A mutant (A) and D524A mutant (B) The structures of bound sugars andthe side-chains of three acidic residues inthe conserved ... important rolein ‘cycling’ the pKa of catalytic Glu during catalysis [24,38] The mutation ofthe D1 residue to Asn (D140N) in SmChiB caused a 500-fold decrease in activity [39] On the other hand, in ... orientations ofthe Glu526 side-chain inthe A-form were almost identical, andthe maximum coordinate shift ˚ after superimposition ofthe two structures was 0.78 A Inthe B-form, in contrast, the Glu526...
... using the concentration of protein inthe extract as an internal standard The activity of ()119/+178) PS1CAT inthe presence ofthe empty vector was taken as 100% The values represented inthe ... all contain the highly conserved ETS domain ERM contains two DNA binding inhibitory domains flanking the Ets domain: the central 87 amino acid inhibitory domain is poorly conserved and virtually ... SK-N-SH and SH-SY5Y cells recognize specifically Ets motifs flanking the +1 site (A) The binding of nuclear factors is eliminated by mutations in Ets motifs The binding of nuclear factors present in...
... loss of penicillin binding Arginines 306 and 307 Fig Proposed binding mode for penicillin N to the iron(II)-2-oxoglutarate complex of DAOCS, showing possible involvement of selected residues The ... The third type of mutant, represented by arginines 306 and 307, are located inthe C-terminus They appear to modulate the activity ofthe C-terminus, which encloses the DAOCS active site during ... proposed mode of penicillin binding by DAOCS [1,12] a key feature of which is that arginines 160 and 162 bind to the carbonyl and/ or carboxylate ofthe bicyclic b-lactam nucleus, with the pro-S methyl...
... two residues andthe edge ofthe substrate ring could prevent binding of 3,6-DMC and 3,5-DMC, as shown in Fig 2D,E,F Thus, the binding of 3,5-DMC and 3,6-DMC to the active site of C2,3O could ... when the side chain makes the closest contact between the residue andthe substrate Lines with round ends indicate stacking between the ring ofthe substrate and His240 in DHBD (A), His248 in HPCD ... To investigate thein uence ofthe side chain of residue Thr249 of C2,3O on the cleavage of 3,5-DMC and 3,6DMC, the catalytic properties of mutants were studied Based on the results of docking...
... game theories New findings out ofthe thesis This thesis presents the following new findings (1) New findings related to theory (a) A new economic equation to relate two levels of sustainable ... to the right of OS line as long as the points are to the left ofthe vertical S line which represents the general sustainability line Gist of Chapter 2: ENVIRONMENTAL CONSERVATION AND TRADE The ... agreements mathematically in terms of environmental conservation The proposed thesis is, therefore, unique, original and very challenging in this aspect The followings are some ofthe important...
... dominant states play quite a signi cant roleinthe formation ofthe business cycle patterns ofthe formar group of states The business cycle patterns ofthe major oil supply states are distinctly ... (2.15) Rather than using only the previous information, it is possible to obtain the probability ofthe economy being in either recession or expansion Pr[St = j j using the full set of information ... level business cycle patterns In face, most ofthe time the state level business cycles of this group lay on the opposite side ofthe national business cycle.Most ofthe states fall into the fourth...