the road goes ever on lord of the rings mp3
CONSTRUCT VALIDATION OF THE JOB PERFORMANCE MEASUREMENT a CASE OF THE MALAYSIAN PUBLIC SERVICE AGENCIES
Ngày tải lên: 11/09/2013, 11:44
Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx
... conformation due to the loss of a stabilizing constraint on the ground state of the receptor. Therefore, the agonist had a lower affinity than the wildtype V 1a R but once the agonist bound, the receptor ... 270) Ó FEBS 2003 Results The effect of systematic substitution of Arg46 on agonist binding The structural requirements of the residue at position 46 in the N-terminus of the V 1a R (Fig. 1) were ... protein. In contrast to the three classes of antagonist, the binding of AVP was dramatically affected by the substitution of Arg46, with the affinity of AVP for all the 19 mutant receptor constructs...
Ngày tải lên: 07/03/2014, 21:20
Economic Impact of the Abolition of the Milk Quota Regime – Regional Analysis of the Milk Production in the EU – doc
... implemented in the baseline. The amounts of the payments are considered a simulation outcome, because they depend on production and they are thus presented in the section of scenario results. The core ... assessment of possible implications of the dairy policy reform, with an explicit focus on regional effects in the EU-27 of a milk quota abolition in the year 2015. Specification of the Model The ... others are open to all countries under the Most-Favoured Nations (MFN) treatment of the WTO. There are some regional exceptions to the operation of the MFN tariffs, such as for example the Everything...
Ngày tải lên: 18/03/2014, 00:20
Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx
... phosphorylation. Effect of RS motif phosphorylation on oligomerization of the N protein To better understand the effect of RS motif phosphor- ylation on the biological function of the N protein, ... together, these data suggest that the RS-rich region of the SARS- CoV N protein is possibly phosphorylated by SRPK1. Phosphorylation of multiple serines within the RS motif The RS motif of the ... cellular functions. Multimerization of the N protein is necessary for nucleocapsid formation and assembly of the viral particles [42]. Thus, whether phosphorylation of the RS motif in virions could...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf
... is the angle between the projection of the tilt of the z axis on the xÂ,y plane (dened direction of tilt of z and the x axis), and j % a + c denes the location of the rhombic (x, y) axes. The ... cyanide. The observation of a significant iso- tope effect on the heme methyl contact shifts confirms a strong contact between the Tyr32(B10) OH and the ligated cyanide. The quantitative determination of ... relaxation properties of the C e Hs signal (see above). The hydroxyl proton position is not directly determined in the crystal structure, but can be inferred by the position of other H- bond acceptor/donors in the...
Ngày tải lên: 23/03/2014, 17:22
Báo cáo khoa học: Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164 doc
... position 2. The substitution positions of all the other monosaccharides were confirmed by GC-MS data of the methylated products to be as presented in Scheme 1. Deamination of the products of complete ... have the D -configuration, and Fuc had the L -configuration. 3-O-Methyl-6-deoxytalose had a positive optical rotation, which confirms its D -configuration. However, the value of the optical rotation ... acetylated. The second procedure led to the reduction of the GlcA residue with the introduction of two deuterium labels at C6. Comparison of the two chromatograms allowed unambi- gous confirmation that...
Ngày tải lên: 23/03/2014, 18:20
Báo cáo khoa học: Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1 doc
... recorded during addition of the first electron (ox/sq transition), whereas dotted lines shows spectra recorded during addition of the second electron (sq/hq transition). The tendency of the protein to ... concentration of the FMN domain is increased indicates that the reaction rate is controlled by some process other than collision of the two flavin-binding domains. Discussion The ability ... addition of the first electron (oxidized-to-semiquinone transition) are indicated by thin, solid black lines. Spectra collected during addition of the second electron to the flavin (semiquinone-to-hydroquinone...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo khoa học: Structure of the O-polysaccharide fromProteus myxofaciens Classification of the bacterium into a newProteusO-serogroup pptx
... the D configuration (the b effect on C3 of L -GlcA wouldbeclosetozero[27]). On the basis of the data obtained, it was concluded that the repeating unit of the O-polysaccharide of P. myxofac- iens has the following ... 61.9, and 62.1, respectively [26], demonstrated the modes of glycosylation of the monosaccharides. The linkage positions were confirmed and the sequence of the monosaccharides was determined using ... The D configuration of GlcN and GalN was established by GLC of the acetylated (S)-2-butyl glycosides. The D configuration of GlcA was determined by analysis of the 13 C NMR chemical-shift data of the polysaccharide...
Ngày tải lên: 23/03/2014, 21:20
Báo cáo khoa học: Expression and characterization of soluble forms of the extracellular domains of the b, c and e subunits of the human muscle acetylcholine receptor pot
... amounts of the ECDs of the non-a sub- units of human muscle AChR for use as starting material for the determin- ation of the 3D structure of the receptor ECDs and for the characterization of the ... expression of c1–219. The presence of the HIS tag alone reduced the expression of both con- structs by 30–40% (Fig. 1B, bars 2 and 6), and further addition of FLAG to c1–218HIS gave 100% expression (construct ... Purification and deglycosylation of the AChR ECDs. (A) Schematic representation of the constructs used for expression of the b1–221, c1–218 and e1–219 ECDs of the human AChR in yeast P. pastoris. The...
Ngày tải lên: 30/03/2014, 10:20
Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx
... the second residue of the primary sequence; the second series consists of a progressive truncation of the C-terminal domain of PufX (Fig. 1) obtained by the introduction of stop codons in the gene sequence ... prior to the onset of the reaction at its maximal rate. In wild-type ICM, the initial rate of this reaction, as well as the lag phase, depends on the redox state of the ubiquinone pool and on the ... (Q B ). The full reduction of the quinone m olecule at Q B to quinol requires a second photoexcitation of the RC and is coupled to the uptake of two protons from the cytoplasmic space. The formed ubiquinol...
Ngày tải lên: 31/03/2014, 09:20
Review of the Literature Regarding Critical Information Needs of the American Public
... in the U.S. devoted to education, but there is no substantiation of this figure, and most of the blogs discuss are professional or academic blogs. There is an extended discussion of nonprofit ... account of the increasing failure of the news ecosystem to adequately report on education nationally and locally, with some suggestions for the formation of a non- profit reporting sector. The third, ... secondary analysis. Although they are a strong overview of the state of education journalism, the studies are only a beginning. The fact that they stand out as they do reflects not only their...
Ngày tải lên: 02/06/2014, 09:39
Báo cáo sinh học: " Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein" docx
... at the highest lipid concentrations, while the monotonic increase and low overall enhancement of LLP-2 and LLP-3 indicates that they are only partially bound at these lipid concentra- tions. The ... insertion and interactions at the membrane-water interface in which the peptides lie on the cell surface to cause a generalized dis- ruption of the membrane. However, our observation of nearly ... is the con- centration of water (55.3 M). The fraction of peptide bound in any experiment can be calculated using the equation Fraction bound = (K x ì [L])/([W] + (K x ì [L])) In the case of...
Ngày tải lên: 18/06/2014, 18:20
Báo cáo hóa học: " Viroporin potential of the lentivirus lytic peptide (LLP) domains of the HIV-1 gp41 protein" docx
... complete partition- ing determined by fitting the equation to the experimental data, [L] is the concentration of lipid and [W] is the con- centration of water (55.3 M). The fraction of peptide bound ... at the highest lipid concentrations, while the monotonic increase and low overall enhancement of LLP-2 and LLP-3 indicates that they are only partially bound at these lipid concentra- tions. The ... in osmolysis. The ability of UV-inactivated HIV to cause sin- gle cell balloon degeneration in the absence of replication argues for the involvement of a virion component, possi- bly the LLP domains...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo hóa học: " The genome and proteome of the Kluyvera bacteriophage Kvp1 – another member of the T7-like Autographivirinae" docx
... are one of the most common types of bacteriophages with 26–29 defined or tentative species according to the VIII report of the International Commit- tee on the Taxonomy of Viruses [3,4]. Most of ... A). The masses of the proteins are indicated in the adjacent lanes. The tentative identification based on in silico analysis of the properties of the gene products (Gp) are indi- cated on the ... above that of the major capsid protein (Gp10) which was not immediately linked, on the basis of its mass, to a product of one of the morphogenesis genes. One of the characteristics of some T7-like...
Ngày tải lên: 20/06/2014, 01:20
Báo cáo khoa hoc:"The 5S rDNA of the bivalve Cerastoderma edule: nucleotide sequence of the repeat unit and chromosomal location relative to 18S-28S rDNA" doc
... and these appear to result from reduction/expansion of the thymidine-rich region at the 5’ end. Excluding the variable sites associated with these thymidine regions, the ... misincorporation. The occurrence of this minimal intra- individual variation and the identification of the same restriction patterns after enzyme digestion in the individuals ... pseudogenes among the repeat units analysed here can be considered improbable. In the spacer region of 5S rDNA, three of the clones analysed are almost identical as only two...
Ngày tải lên: 09/08/2014, 18:21
Báo cáo y học: "Surgical fasciectomy of the trapezius muscle combined with neurolysis of the Spinal accessory nerve; results and long-term follow-up in 30 consecutive cases of refractory chronic whiplash" pps
... 7-156) and 24 months, respectively. All of the patients stated that their condition had reached a steady state at the time of the operation. Fourteen patients reported that their condition had been ... with the shoulder elevated on the side of greatest pain; (2) decreased and painful range of motion in neck and shoul- der(s); (3) tenderness to palpation along the horizontal portion of the upper ... exclude that the most beneficial part of the surgery described herein was decompression of a chronic compartment syndrome in parts of the segmented trapezius muscle. Limitations The conclusions that...
Ngày tải lên: 10/08/2014, 10:20