the proximal interphalangeal joints of the fingers flexion
Báo cáo y học: "proximal interphalangeal joints in rheumatoid arthritis: a comparison with magnetic resonance imaging, conventional radiography and clinical examination" pdf
Ngày tải lên :
09/08/2014, 07:20
... conducted in the accessible aspects of the second to fifth MCP joints and the second to fifth PIP joints of the dominant hand: the dorsal, radial and palmar aspects of the second MCP joint; the dorsal ... presence of signs of inflammation in 103 joints (21% of the 480 joints) and on Page of 11 (page number not for citation purposes) the absence of signs of inflammation in 268 joints (56%) In 91 joints ... Localization of signs of inflammation showed the dominance of the palmar aspect in PIP joints and a slight dominance of the dorsal aspect in MCP joints In our opinion, the uneven distribution of signs of...
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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: chemokines in the joints of patients pdf
Ngày tải lên :
18/02/2014, 18:20
... Chemokines in the joints of patients T Iwamoto et al positive chondrocytes results in a specific increase in the release of MMP-3 [10] Pathological concentrations of SDF-1 ⁄ CXCL12 induce the death of human ... enhances the proliferation of FLS [13,47] Our group reported that the proliferation of FLS by MCP4 ⁄ CCL13 is dependent on activation of the extracellular regulated kinase MAPK The activation of MAPK ... mainly by TNF-a The role of chemokines in RA pathogenesis The chemokines listed above are implicated in RA pathogenesis via the recruitment and retention of leukocytes in the joints In addition...
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
Ngày tải lên :
18/03/2014, 01:20
... of the extracellular part of the receptor [28] Therefore, analysis of the ability of the mutants gp130D4 and gp130D4 to form complexes with the LIFR by coprecipitation was not possible with the ... other but have no contact, thus diminishing the distance of the C-terminally located domains D5 of gp130 serves as a contact site with D7 of the LIFR The membrane -proximal D6 of gp130 and D8 of ... to the CBM that play specific roles in activation of the receptor by these two cytokines The ligand independent activation of the D5-GCSFR chimera occurs in both the absence and the presence of...
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Báo cáo y học: "Differential gene expression of bone anabolic factors and trabecular bone architectural changes in the proximal femoral shaft of primary hip osteoarthritis patients" pptx
Ngày tải lên :
09/08/2014, 08:23
... produced by the various bone marrow and bone cell types in the bone microenvironment [42,43] The role of these growth factors suggests their involvement in the preservation of the bone matrix The two ... staff of the Department of Orthopaedics and Trauma in the Royal Adelaide Hospital for support and cooperation in the collection of femoral specimens and to the mortuary staff of the Institute of ... comprises the majority of the organic matrix of bone, it is not unique to the tissue [37] Thus, non-collagenous proteins such as OCN and OPN have become the focus of studies aimed at the elucidation of...
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Báo cáo y học: " The utility of MRI in predicting radiographic erosions in the metatarsophalangeal joints of the rheumatoid foot: a prospective longitudinal cohort study" pdf
Ngày tải lên :
09/08/2014, 14:21
... erosion in the same joint at a subsequent time point The design of this study permitted the calculation of these parameters at 6, 12, and 24 months between the detection of the MRI erosion and the subsequent ... because these lesions are persistent on subsequent studies The reversibility of the other lesions did not allow meaningful analysis since we could not relate the timing of therapies to the timing of ... constructed without taking into account the hierarchical nature of the data and therefore are likely to underestimate the standard error of the OR estimates The number of new radiographic erosions was...
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Báo cáo y học: "Influence of static lumbar flexion on the trunk muscles'''' response to sudden arm movements" potx
Ngày tải lên :
13/08/2014, 13:22
... and therefore provide little stability Muscles function much like guy wires on a ship's mast The greater the tension in the guy wires and the greater the number of guy wires, the greater the ... that the trunk motion occurred, how much force was applied to cause the perturbation and the resulting onset time and amplitude of the EMG signals of the trunk muscles to calculate the timing of ... and the hips flexed and externally rotated to allow the soles of the subject's feet to touch one another The subject then maximally forward flexed their spine and attempted to "hang" on the passive...
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Báo cáo hóa học: " A new electromechanical trainer for sensorimotor rehabilitation of paralysed fingers: A case series in chronic and acute stroke patients" pdf
Ngày tải lên :
19/06/2014, 08:20
... were attached to the inner surface of the concave roll of the index finger, and the patients were asked to discriminate between them Patients with arthritis of the finger joints, soft tissue pain ... frequency The patient practised a total of 15 with the device The patients were instructed to concentrate on the movement of the paretic fingers and, if possible, to imagine that they themselves ... positioning the hand & fingers in the device The treatment of the plegic fingers after stroke is pertinent given their large cortical representation, the presumed competition between proximal and...
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Báo cáo y học: "CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease" potx
Ngày tải lên :
09/08/2014, 01:23
... [21] The presence of erosions is clinically analyzed in the small joints of hands or feet, which are the joints first affected in RA Thus, the X-ray analysis clearly answers the questions of whether ... only the RA patients in graphic format The other patient groups were, however, also studied and the results are presented at the end of this section The first question we addressed was whether the ... accumulation of CD25brightCD4+ T cells in the inflamed joints is dependent on the chronicity of the disease We thus investigated whether disease duration was correlated with the frequency of CD25brightCD4+...
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Báo cáo y học: "A proinflammatory role for Fas in joints of mice with collagen-induced arthritis" docx
Ngày tải lên :
09/08/2014, 01:23
... total number of mice), the mean score (total score of diseased mice divided by total number of mice), and the mean day of onset of disease (total days of onset divided by the number of diseased ... infiltrating the rheumatoid synovium are resistant to apoptosis either because of expression of the anti-apoptotic proteins bcl2 and bclxl or because of deficiency of FasL On the other hand, conflicting ... or mild inflammation of the whole paw; 3, severe inflammation of whole paw or ankylosis For evaluating the susceptibility of mice to CIA, the incidence of disease (number of diseased mice divided...
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Báo cáo y học: "Increased lymphangiogenesis in joints of mice with inflammatory arthritis" pptx
Ngày tải lên :
09/08/2014, 10:21
... removed from their limbs Long bones together with a front or rear paw were cut from the limbs Forceps were used to loosen the joints The joints were then cut open and digested with mg/mL of collagenase ... major source of VEGF-C in arthritic joints of TNF-Tg mice To confirm that there is elevated TNF or IL-1 expression in the joints of TNF-Tg mice, we measured the expression levels of TNF and IL-1 ... manuscript preparation and had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis QZ and STP participated in study...
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Tài liệu Báo cáo khoa học: Critical roles of Asp40 at the haem proximal side of haem-regulated phosphodiesterase from Escherichia coli in redox potential, auto-oxidation and catalytic control doc
Ngày tải lên :
19/02/2014, 16:20
... differences in the spectral maxima in the visible region of the Fe(III) species, spectra of the Asp40 mutants were essentially similar to that of the wild-type protein Additionally, spin states of the Fe(III), ... mM)1Æs)1) of the wild-type protein (Table 2) The data indicate that mutation of Asp40 at the haem proximal side alters the cyanide binding property only slightly, and may not significantly affect the ... significantly affect the binding of exogenous ligands, such as the cyanide anion, to the Fe(III) complex [17], and O2 and CO to the Fe(II) complex [18] However, the PDE activities of these mutants are...
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The Six Fingers of Time ppt
Ngày tải lên :
15/03/2014, 06:20
... touching the fingers of the secret; and always, when he came near it, it had a little bit the smell of the pit For he had pegged out all the main points of the history of man; or rather most of the ... admittance But there could be no entertainments in the clubs There was nothing there but the little bar room in the near darkness The man was there, and then he was not, and then he was there again ... know of the laws of mass, momentum, and acceleration, as well as those of conservation of energy, the potential of the human person, the moral compensation, the golden mean, and the capacity of human...
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Báo cáo khoa học: Probing the catalytic potential of the hamster arylamine N-acetyltransferase 2 catalytic triad by site-directed mutagenesis of the proximal conserved residue, Tyr190 pot
Ngày tải lên :
16/03/2014, 00:20
... truncations, the availability of the Tyr190 mutants makes it feasible to conduct cell-based studies of the effects of the stability of the acetylated enzyme intermediate on the N-acetylation of aromatic ... mechanism, the acetylation rate (k2) of NAT2 by the acetyl donor is independent of the transacetylation rate (k4) of the arylamine substrate Because the values of k4 for PABA can be inferred from the ... kinetic evidence for the similarity of the Tyr190 to Phe mutant and wild-type However, the rate of acetylation of NAT2 (k2) is 5-fold lower than the wild-type, and the stability of the FEBS Journal...
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Báo cáo khoa học: The influence of cholesterol on the interaction of HIV gp41 membrane proximal region-derived peptides with lipid bilayers potx
Ngày tải lên :
23/03/2014, 07:20
... all the peptide is in the water or lipidic phase, respectively; cL is the lipidic molar volume [26] and [L] is the concentration of the lipid accessible to the peptide (the outer leaflet of the ... reach the point where all of the membrane is homogeneous The MPRP-C is insensitive to the cholesterol content in the membrane, which is in agreement with the insensitivity of the peptide to the ... about the interaction of peptides with large unilamellar vesicles (LUV) The fluorescence quantum yield is dependent on the polarity of the microenvironment of the Trp residues, as well as on the...
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IIW RECOMMENDATIONS ON METHODS FOR IMPROVING THE FATIGUE STRENGTH OF WELDED JOINTS pot
Ngày tải lên :
24/03/2014, 02:20
... range These are of the form Δσ m N = constant, where Δσ is the stress range, N is the fatigue life and m is the inverse slope of the log Δσ vs log N curve The benefits from the use of the improvement ... (arrowed) Fig 5.5 The diameter of the tool tip influences the resulting appearance of the hammer peened surface In general, the smaller the diameter, the greater the likelihood that the actual weld ... variations is the lack of standardization of the optimum method of application, but variations in the material, type of loading and type of weld detail may also have influenced the results The effectiveness...
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analysis and determination of the stress intensity factor of load-carrying cruciform fillet welded joints
Ngày tải lên :
24/05/2014, 20:40
... Figure (4) shows the results of a crack increment step (Δa) It was noticed that there are no effects on the stability of results and the very close agreements between the three types of a crack increment ... perpendicular to the direction of the applied stress, where it was predicted that critical tensile stresses would occur Having specified the location of the crack, the program was able to predict the direction ... the crack would propagate Prior to performing the analysis, it was necessary to specify the magnitude of crack increment and also the number of steps over which the crack would propagate In the...
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báo cáo hóa học: " Analysis of right anterolateral impacts: the effect of trunk flexion on the cervical muscle whiplash response" potx
Ngày tải lên :
19/06/2014, 10:20
... and 4% for the left sterncleidomastoid) As the level of applied acceleration in the impact increased, the magnitude of the EMG recorded from the trapezius ipsilateral to the trunk flexion increased ... DJ, Lustic L, et al.: The effect of the initial position of the head and neck on the dynamic response of the human head and neck to Gx impact acceleration In Proceedings of the Nineteenth Stapp ... with the trunk flexed 45 degrees to the right or left, the trapezius muscle ipsilateral to the direction of trunk flexion shows the greatest EMG response (p < 0.05) The normalized EMG for the...
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báo cáo hóa học:" Asymmetry and structural system analysis of the proximal femur meta-epiphysis: osteoarticular anatomical pathology" ppt
Ngày tải lên :
20/06/2014, 01:20
... were normalized (the procedure of dividing of the mean of each linear parameter by the mean of the transverse diameter of the femoral diaphysis) Therefore, the deviation of the measurement becomes ... parameters of the femoral head confirm the hypothesis that the proximal parts of the femur act at a level that transmits load to the knee joint [28-31] The centre of the femoral head is the place of ... of the proximal epiphysis (J) and the diameter of the femoral head may indicate the predominance of the left extremity in provid- ing movements in the hip joint and also the maintenance of the...
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báo cáo hóa học:" Post-traumatic flexion contractures of the elbow: Operative treatment via the limited lateral approach" doc
Ngày tải lên :
20/06/2014, 01:20
... this in 30% of cases The patients in our study did not have significant restriction of flexion and were therefore only treated for lack of extension In 18 of the 23 cases (79%) the flexion contracture ... structures of the elbow and is therefore not as useful The medial approach does permit access to the anterior and posterior parts of the joint and exposes the ulnar nerve [32] but the radial ... Figure photograph showing the anterior capsule of the elbow through the lateral approach A clinical A clinical photograph showing the anterior capsule of the elbow through the lateral approach mostasis...
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báo cáo hóa học:" Modular endoprosthetic replacement for metastatic tumours of the proximal femur" doc
Ngày tải lên :
20/06/2014, 01:20
... completed assessment of function [14] We analysed the patient and prosthetic survival, the risk of revision of the prosthesis, the incidence of failure of limb salvage because of amputation and ... following the use of the modular prosthetic replacement of the proximal femur We have used Kaplan Meier survival curves to assess the failure rates of the prostheses We have compared these outcomes ... outcomes [126] The proximal femur is the commonest long bone to be affected by secondary malignant bone tumours [1,2] The use of endoprostheses for the treatment of malignant tumours of the proximal...
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