the problem of data integration in cancer research

... were integrated in the US into a much larger interagency initiative towards ‘an integrated approach to research in psychological health and traumatic brain injury’ This initiative included working ... of the more extensive information contained in continuous monitoring We strongly advocate further development of software aimed at capturing the frequency distribution of measured values during ... continuous monitoring and further research into the best approaches to analysis These developments may well constitute one of the most important steps forward in the field of clinical trials in...

Ngày tải lên: 13/08/2014, 19:20

... utilization of the produced byproducts and sustaining animal production The future of animal protein in poultry diets in reality lies within the decisions made by the industry itself and the consumers of ... directed at prohibiting the use of certain mammalian proteins in feed for cattle and other ruminants have affected the handling and usage of all animal protein products by the feed industry But if ... United States beginning in 1986 following the first confirmatory diagnosis of BSE in the United Kingdom, has resulted in no cases of BSE found in U S cattle nor have any cases of the human form,...

Ngày tải lên: 08/03/2014, 09:20

... from the aforementioned groups, organizing the logistics of mail-outs and meetings, and sharing in the writing and editing of the many versions of the FMEC Collective Vision Thank you, Nick Busing, ... and the Faculties of Medicine A starting point for implementing this vision can be found in the efforts of the Canadian Faculties of Medicine to adapt medical education to evolving realities In ... contributed to the careful language used in each as well as to the development of the enabling recommendations The following report is the final product of this collaborative initiative Next Steps The AFMC...

Ngày tải lên: 14/03/2014, 20:20

... after the trade (including the price impact due to the information in the trade) This cost can be interpreted as the profit realised by the other side of the trade, assuming they could lay off the ... entirely independent of the UK Government As such, the findings not represent the views of the UK or any other government, or the views of any of the organisations that have been involved in the work ... execution costs Of course, additional studies linking HFT and institutional trading costs in other market settings would be helpful in determining the generality of this finding In summary, the evidence...

Ngày tải lên: 29/03/2014, 18:20

... years in the research cohort database) There was also a higher incidence and 233% better reporting of genital herpes in the routine clinic than in the research cohort database Data audit In the audit ... cohort database (n = 559) Type of OI Routine clinic database (n = 559) Routine clinic database (n = 1233) % underreporting of OI % events in 559 patients in underreporting routine clinic vs of OI research ... in both databases, the incidence rate in the clinic database was slightly higher because of the smaller number of person years in the routine clinic database (769.2 years versus 847.5 years in...

Ngày tải lên: 20/06/2014, 08:20

... resulted in the accumulation of detailed data on 2995 attempts to place intraosseous cannulas from a total of 732 Scandinavian health care workers Analysis of the data is pending Having data on ... extensive administrative work regardless of the amount asked for In addition, it may be hard to convince institutional donors to offer microgrants because of the low profile of many of the projects ... microgrant initiatives could therefore include offers of support from fellow researchers [1,10,11] Conclusion Microfinance in the form of microgrants can be used to facilitate research in emergency...

Ngày tải lên: 13/08/2014, 23:21

... numerical models in oceanographic forecasting is encompassed in the term data mining The original philosophy behind data mining is the attempt to circumvent the numerical models Data mining has become ... Discarding the experience accumulated by the refinement of theories also makes data mining less convincing to the researchers who wonder about the science still undiscovered in the data With the ... the Lorenz time series, in which the parameters are determined by both the standard approach and the inverse approach The data set is divided into two subsets, i.e training data and testing data...

Ngày tải lên: 11/09/2015, 10:15

... data by  offering  a  summary  of the research results  and  an  invitation  to  a  free  workshop  on  the research findings.  These  helped  ensure  the respondents’  professional  interest  ... experiencing  dynamic  reshaping: both brick‐and‐mortar and pure‐clicks retail firms are in the midst  of searching, innovating and adapting to the right mix of “hybrid‐ness”. The building  of physical  ... to  them  at  any  point  in time.  They relish the ability to be able to perform the different stages in completing  a transaction either online or in the store  (The Economist 2005).   In ...

Ngày tải lên: 11/09/2015, 16:08

... Relaxation of the smooth muscle of the trabeculae then dilates the lacunae, allowing for the expansion of the erectile tissue against the tunica albuginea which in the process, compresses the subtunical ... This recycling helps to ensure that there is sufficient concentration of arginine for production of NO The main site of NO production in human CC 17 is in the terminal branches of the cavernous ... against the tunica (the stretching of the tunica also compresses the emissary veins), restricting the venous outflow Penile erection is achieved through this combined increase in arterial inflow...

Ngày tải lên: 12/10/2015, 17:33

... source of innovation Indeed, one of the most striking findings of this survey is the sharp rise in the role of the customer in generating new ideas By 2020, customers are expected to overtake in- house ... shopkeepers out of business Looking ahead, growth innovation must outstrip the ability of the other two to take jobs out of the economy But in the US and parts of Europe, businesses are investing less ... less in these kinds of innovation, while engaging in more efficiency innovation Q: In our survey, many firms cited customers as a major source of innovation in the coming decade, ahead of more...

Ngày tải lên: 04/12/2015, 00:04

... The future of healthcare IT in South Korea Convincing the patients Others point out that among all the talk of policy, financing, and conflicting views within the medical community, in the race ... and the MoKE, with the two-pronged goal of improving healthcare delivery and fostering the local healthcare industry According to Lim In- taek, until recently director of the Bureau of Health Industry ... with [the benefits of having] IT in their hospitals if they can use it for free But the amount of investment is beyond their means, so they’re reluctant They know it’s good to have—when they go...

Ngày tải lên: 06/12/2015, 23:05

... the US is paying to generate all these data - probably the majority of genomics data is coming from the US at Page of present - but where it’s not prepared to meet the cost of archiving the data ... being deleted RK: If there is a good chance that the data are going to be used by others, then yes, there is a good case for storing them Just storing the raw data for the sake of it, however, is ... SRA data into MG-RAST) MG: My impression is that they’re certainly not going to delete all of that How will other data repositories fare in the future given the data deluge that is occurring?...

Ngày tải lên: 09/08/2014, 22:23

... [29], the UP1 box mediating the transcription of protein synthesis [30], and the G box inducing the transcription of photosynthesis genes in response to light [31] The observation that 71% of these ... patterns within the set of genes containing the same module As shown below, these new motifs can be missed in the first detection stage on coexpressed genes since the fraction of genes containing this ... enhance the identification of new TFBSs reports *Numbers in parentheses indicate the number of clusters (containing co-expressed genes) in which the motif was independently identified The letters in...

Ngày tải lên: 14/08/2014, 17:22

... condition selection increases the combinatorial nature of the problem, DISTILLER relies on the closed itemset mining strategy CHARM [44] instead of Apriori [45] This change in itemset mining algorithm ... reduced the number of user-defined parameters, thereby enhancing the interpretability of the results This pruning step results in a massive speed-up, making the method applicable to large data sets ... include the intergenic region between the gene of interest and its upstream gene and the first 50 nucleotides of the genes' coding region Note that since only the first operon gene will contain the...

Ngày tải lên: 14/08/2014, 21:20

... set, data cleansing and preprocessing, data reduction and projection, choosing data mining task, choosing data mining algorithm, data mining, interpreting the mined patterns and consolidating the ... 2013) 19 2.4 Data mining and Knowledge discovery Data mining is the process of examining volumes of data in multiple contexts to abstract the data into useful information (Palace, 1996) The five ... wealth of information available in the public domain to gain new knowledge The goals of this thesis were: (i) the adoption of existing analysis strategies or the development of novel approaches in...

Ngày tải lên: 25/11/2015, 13:26

... chemokines in monocytes and macrophages (including Kupffer cells) [41, 42], and ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of the gut ... resistance against anticancer drugs including vinblastine, topotecan, paclitaxel and doxorubincin in human hepatocellular carcinoma derived cell lines The resistance against anticancer drugs ... of ethanol (100 mM) induced the expression of genes involved in the metabolism of ethanol [16] In addition, the metabolism of ethanol 33 results in an increased production of toxic metabolites...

Ngày tải lên: 31/10/2012, 15:28

... from the not poor, the comfortable from the slum dweller Thus within the world of DHS data, a young child struggling to survive on the garbage dumps of Manila or in the City of the Dead in Cairo ... because of the rapid pace of urbanization in that area In the next decade most of the U.S Agency for International Development’s clients in the region will be living in urban areas, so the question ... the significance of urbanization with respect to the health of the poorest children living in the poorest settlements in cities The underlying purpose of this study is to support the design of...

Ngày tải lên: 12/02/2014, 12:20

... Evaluation of ASTER data use in land use study in the Mekong Delta 29 discrimination capacity of ASTER data in land use mapping of such a dynamic area as the Mekong Delta in Vietnam Forest ... different types of land cover These combinations will be used for the classification for the land cover types for which the combination is the most discriminative Due to the constraints of the spatial ... even of 15m are still limited for the detailed land use mapping of the studied area Instead of this, ASTER data provide a wide range of spectra and we assume that there exist some combinations of...

Ngày tải lên: 13/02/2014, 12:20

... valueOf, in class Integer, converts the String to an Integer wrapper The intValue function then converts the Integer to an int An alternative method of doing the same thing is the following: String ... objects since the constructor for class Line requires creating a line in terms of its two end points and we cannot access the end points for the two input lines in class LineHolder since they are ... Line(pt1, pt2); Line line2 = new Line(pt3, pt4); Line line3 = new Line(pt5, pt6); LineHolder lineHolder1 = new LineHolder(line1, line2); LineHolder lineHolder2; lineHolder2 = (LineHolder) lineHolder1.clone();...

Ngày tải lên: 14/02/2014, 04:20