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Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc

Tài liệu Báo cáo khoa học: Characterization of the promoter for the mouse a3 integrin gene Involvement of the Ets-family of transcription factors in the promoter activity doc

... CCAAT box at 324 bp upstream of the major transcription start site. The presence of a CCAAT box and the absence of a TATA box seem to be one of the characteristics of the mouse integrin a3 gene. We ... We previously reported the structures of the mouse a3integrin subunit gene including the exon/intron organization and the alternative exon usage for the generation of variants of the a3 subunits (a3A ... upstream of the SacI) sites (Fig. 1). Sequence analysis of the 5Â-anking region and determination of transcription start sites of mouse integrin a3 subunit gene The nucleotide sequence of the 0.5...

Ngày tải lên: 21/02/2014, 03:20

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Tài liệu Euphorion Being Studies of the Antique and the Mediaeval in the Renaissance - Vol. II pot

Tài liệu Euphorion Being Studies of the Antique and the Mediaeval in the Renaissance - Vol. II pot

... imagine the old knight, only half aware of the sunshine of the evening, the noise of the streets, the looks of the crowd, the great minster rising half-finished in the midst of the town by the Rhine, ... Boiardo, of the Ferrarese court to which he belonged, and of the school of poetry (including the more notable but less original work of Ariosto) which the genius of the man and the character of the ... this: on the extreme pinnacle, high on the roof, they might indeed place against the russet brick or the blue sky, amid the hum of life and the movement of the air, the living man, like the Scaligers,...

Ngày tải lên: 21/02/2014, 21:20

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Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx

Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx

... mutation of Arg46 had the dual effect of (a) decreasing agonist affinity and (b) promoting the agonist-induced active conformation due to the loss of a stabilizing constraint on the ground state of the ... in which each of the 19 alternative amino acids encoded by mRNA were substituted at position 46 and the biological characteristics of the mutant receptors assessed. None of the other amino acids ... with the corresponding sequence of the V 1a R [10]. The role of the N-terminus has been addressed recently by alanine-scanning mutagenesis of the N-terminus of the V 1a R; this revealed that a...

Ngày tải lên: 07/03/2014, 21:20

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Economic Impact of the Abolition of the Milk Quota Regime – Regional Analysis of the Milk Production in the EU – doc

Economic Impact of the Abolition of the Milk Quota Regime – Regional Analysis of the Milk Production in the EU – doc

... Impact of the Abolition of the Milk Quota Regime – Regional Analysis of the Milk Production in the EU" (AGRI-2007-0444). The project aimed at a thorough policy impact analysis of the EU ... through either the transfer of an entire farm, the leasing or purchase of quota, or the allocation of quota from a national reserve. The transfer of milk quota may take place via a variety of administrative ... average, with +35.5% in the EU-10 and +13.8 in the EU-15. This excess supply makes the net trade position of the EU-27 stronger towards the Rest of the World. Within the EU there is a quite heterogeneous...

Ngày tải lên: 18/03/2014, 00:20

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Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx

Báo cáo khoa học: Phosphorylation of the arginine/serine dipeptide-rich motif of the severe acute respiratory syndrome coronavirus nucleocapsid protein modulates its multimerization, translation inhibitory activity and cellular localization pptx

... copies of the N protein, respectively. (C) The RNA binding efficiency of N protein is represented as a percentage of bound RNA (i.e. the percentage of bound RNA = 100%)percentage of free probe). The ... phosphorylation. Effect of RS motif phosphorylation on oligomerization of the N protein To better understand the effect of RS motif phosphor- ylation on the biological function of the N protein, we Fig. 3. The translation ... that of the full-length N protein (data not shown). Taken together, these data suggest that the RS-rich region of the SARS- CoV N protein is possibly phosphorylated by SRPK1. Phosphorylation of...

Ngày tải lên: 23/03/2014, 07:20

12 432 0
Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf

Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf

... between the projection of the tilt of the z axis on the xÂ,y plane (dened direction of tilt of z and the x axis), and j % a + c denes the location of the rhombic (x, y) axes. The orientation of the ... at position E7 as the source of the H-bond to ligand on the basis of a partial sequence, which had indicated a Tyr on the distal E-helix. The similarity in the 1 HNMRspectraofthe three globin ... ligand. Comparison of the strengths of dipolar interactions in solution with the alternate crystal structures of methemo- globin establish that the solution structure of wild-type Hb more closely resembles the...

Ngày tải lên: 23/03/2014, 17:22

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Báo cáo khoa học: Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164 doc

Báo cáo khoa học: Structure of the exceptionally large nonrepetitive carbohydrate backbone of the lipopolysaccharide of Pectinatus frisingensis strain VTT E-82164 doc

... and showed, in particular, the configuration of ManNAc to be D . From the combined the data on the structures of the isolated oligosaccharides, the overall structure of the P. frisingensis LPS carbohydrate ... with 7a (Table 1) because of the b- effect of the acetylation. Acetylation of 7b was confirmed by ESI MS data, which gave the expected mass of 3221.4 Da. The spectra of oligosaccharide 6 were ... 3-O-methyl- 6-deoxytalose, as setting the L -isomer instead of the D -isomer resulted in the disappearance of the contact between protons U6 and P4. To determine the absolute configurations of the mono- saccharides,...

Ngày tải lên: 23/03/2014, 18:20

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Báo cáo khoa học: Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1 doc

Báo cáo khoa học: Determination of the redox potentials and electron transfer properties of the FAD- and FMN-binding domains of the human oxidoreductase NR1 doc

... FAD/NADPH domain (% 16-fold) (29). However, the domain mixture still recon- stituted only % 2% of the activity of the full length CPR. In thecaseofNR1,thek cat for the full length enzyme is low (1.3 s )1 ) ... enzymes, the potentials for the FAD/NADPH domains are rather more negative than those for the FMN domain, reflecting the direction of electron transfer from NADPH through FAD, then FMN and on to the ... BM3 [28]. Aggregation of the NR1 FAD/NADPH domain was much less extensive in the absence of cofactor reduction. Stopped-flow kinetic studies Reduction of the FAD/NADPH domain of NR1 was investigated...

Ngày tải lên: 23/03/2014, 21:20

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Báo cáo khoa học: Structure of the O-polysaccharide fromProteus myxofaciens Classification of the bacterium into a newProteusO-serogroup pptx

Báo cáo khoa học: Structure of the O-polysaccharide fromProteus myxofaciens Classification of the bacterium into a newProteusO-serogroup pptx

... LPS) [5,6]. The serological specificity of the bacteria is defined by the structure of the O-specific polysaccharide chain (O-antigen) of the lipopolysaccharide. On the basis of the O-antigens, the strains ... the D configuration (the b effect on C3 of L -GlcA wouldbeclosetozero[27]). On the basis of the data obtained, it was concluded that the repeating unit of the O-polysaccharide of P. myxofac- iens has the following ... 2.01–2.10. These data together suggest that the tetrasaccharide repeating unit of the polysaccharide consists of two residues of GlcNAc and one residue each of GalNAc, GlcA and AlaLys. The 1 Hand 13 C...

Ngày tải lên: 23/03/2014, 21:20

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Báo cáo khoa học: Expression and characterization of soluble forms of the extracellular domains of the b, c and e subunits of the human muscle acetylcholine receptor pot

Báo cáo khoa học: Expression and characterization of soluble forms of the extracellular domains of the b, c and e subunits of the human muscle acetylcholine receptor pot

... amounts of the ECDs of the non-a sub- units of human muscle AChR for use as starting material for the determin- ation of the 3D structure of the receptor ECDs and for the characterization of the ... data from electron images of the AChR found in large amounts in the electric organ of the marine ray, Torpedo californica [3]. The acquisition of the crystallo- graphic structure of the mollusc acetylcholine-binding protein ... domain [3]. The N-terminal ECD of each of the two a subunits con- tains the major part of the binding site for the cho- linergic ligands. The two sites are nonequivalent, one being formed at the interface...

Ngày tải lên: 30/03/2014, 10:20

12 394 0
Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx

Báo cáo khoa học: Role of the N- and C-terminal regions of the PufX protein in the structural organization of the photosynthetic core complex of Rhodobacter sphaeroides pptx

... demonstrated the role of PufX in the orientation of the RC inside the LH1 Fig. 4. Isolation of the PMCs on a sucrose gradient. The final detergent extracts from the ICM were loaded on the top of a 10–40% ... PufXD 2)7 neither affects the photo- synthetic capability of the bacteria nor the efficiency of exchange of the ubiq uinol molecules between th e RC and the bc 1 , a s judged from the reduction kinetics of ... residues of the LH1 a polypeptide in the organization of the LH1–RC complex [12]. In the present work, we have investigated the possible involvement of the N-terminus and of the C-terminus of PufX...

Ngày tải lên: 31/03/2014, 09:20

9 547 0
The Covenants And The Covenanters Covenants, Sermons, and Documents of the Covenanted Reformation doc

The Covenants And The Covenanters Covenants, Sermons, and Documents of the Covenanted Reformation doc

... power, in the beauties of holiness; from the womb of the morning thou hast the dew of thy youth. There were many evident proofs of the truth of this since the beginning of the plantation of the gospel into ... First, The uncertainty of the subject. Second, The ambiguity of one phrase. 1. The uncertainty of the subject, or person of whom the prophet speaks here: whether of Christ, by way of prophecy, or of ... and feet, Europe, and the toes the Isles of the Sea the British Isles with the rest. And the form of the great earth-filling figure is that of Jesus of Nazareth, the Man of Jehovah's right...

Ngày tải lên: 31/03/2014, 14:20

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Review of the Literature Regarding Critical Information Needs of the American Public

Review of the Literature Regarding Critical Information Needs of the American Public

... in the U.S. devoted to education, but there is no substantiation of this figure, and most of the blogs discuss are professional or academic blogs. There is an extended discussion of nonprofit ... that the traditional methodological approaches, and their traditional points of focus, lack relevance today. However, the complexity of the changes taking place and the shifting nature of the ... outlining the historical context of health and media studies, the authors describe major individual-level theoretical frameworks applicable in the area: social cognitive theory, the theory of reasoned...

Ngày tải lên: 02/06/2014, 09:39

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báo cáo sinh học:" The current shortage and future surplus of doctors: a projection of the future growth of the Japanese medical workforce" pdf

báo cáo sinh học:" The current shortage and future surplus of doctors: a projection of the future growth of the Japanese medical workforce" pdf

... high: the number of consultations per capita is higher in Japan than in any other OECD country [9], and the rates of hospital utilization are high as well. These trends have made the shortage of ... resolve shortages of health professionals by actively recruiting doctors from other countries. In the 1990s, for example, when the United Kingdom was facing a shortage of doctors, the National Health ... a serious doctor surplus in the future, especially because the population of Japan is decreasing. The purpose of this research is to project the future growth of the Japanese medical doctor workforce...

Ngày tải lên: 18/06/2014, 17:20

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