the presence of shared visual information
Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx
... of a-synuclein incubated alone (A), in the presence of 100 lM MPTP (B), in the presence of 200 lM MPTP (C), in the presence of 100 lM MPP+(D), in the presence of 200 lM MPP+(E), in the presence ... solu-tion of ThT and the fluorescence intensity of the solu-tion was measured at 482 nm. Figure 4A shows the kinetics of aggregation of a-synuclein in the presence of 100 lm MPTP and the effect of 50 ... 1B shows the patternseen after the development of the blot. With increasein time of incubation, the intensity of the band for the monomeric protein decreased, whereas the bands for the higher...
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Tài liệu Bond Market Structure in the Presence of Marked Point Processes doc
... 3.5 From the point of view of economics, discounting meansthat the locally risk-free asset is chosen as the “num´eraire”, i.e. the prices of all other assets are evaluated in the units of this ... interpretation of the above definition is that gtis the number of units of the risk-free asset held in the portfolio at time t .The object ht(dT ) is interpreted as the “number” of bonds, with ... ct(E), and the equality is understoodmodulo λcQ(t, dy), the image of the measure λQ(t, dx) under the mappingct.Since the right-hand side of (55) is a class of equivalence, the rigorousformulation...
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Tài liệu Báo cáo khoa học: NMR structural characterization of HIV-1 virus protein U cytoplasmic domain in the presence of dodecylphosphatidylcholine micelles doc
... undetectable in the presence of Mn2+. The sol-vent-exposed C-terminus of VpUcyt probably pointedaway from the surface of the micelle. The three amidecross-peaks originating from the hydrophobic ... of VpUcyt in detergent-free buffer con-firmed the absence of a secondary structure (Fig. 1). The presented data are the most comprehensiveaccount of the lack of a conformational preference of VpUcyt ... probes16-doxylstearic acid in the interior of the micelle (A) and Mn2+in the aqueous buffer (B) selectively attenuate distinct regions of VpU-cyt, reflecting the topology and the dynamics of the micelle-associ-ated...
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Tài liệu Báo cáo khoa học: Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation ppt
... assay in the presence of stearate (Table 1). The good fit of Model III pro-gress curves to the experimental data supports the concept that in the presence of stearate the catalyticmechanism of plasmin ... parameters of plasmin in the presence of fatty acids. The values of kpand Kmwere determined from the amidolyticassay of plasmin activity, according to Model I, in the presence of oleate (OA) ... N is the total number of measurement points) is presented by the numbers in boxes.Fig. 3. Comparison of three models for the catalytic action of plas-min in the presence of stearate. The p-nitroaniline...
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Tài liệu Báo cáo khoa học: Altered inactivation pathway of factor Va by activated protein C in the presence of heparin doc
... minimize the FXa cofactor activity of the reactionintermediate, FVaint. This facilitated the determination of loss of FVa cofactor activity during the initial stage of inactivation and minimized the ... indicating that the stimulatory effect of heparin on the cleavage atArg306 is also observed in the presence of FXa.Theoretically, the addition of heparin may induce the formation of a binary FXa–FXa ... phase of the reaction,as compared with inactivation in the absence of DEGR-FXa. Addition of 25 IUÆmL)1UFH in the presence of DEGR-FXa stimulated the APC-mediated inactivationapproximately twofold...
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Tài liệu Báo cáo khoa học: Gene transcription of fgl2 in endothelial cells is controlled by Ets-1 and Oct-1 and requires the presence of both Sp1 and Sp3 pdf
... that the constitutiveexpression of this gene is controlled by Ets-1 and requires the presence both of the Sp1 and Sp3 transcription factors. The presence of this complex multicomponent PRD in the ... indicates the nucleotide thatis matched to the band present in the primerextension reaction on the right. The sequence of the primer is 5¢-CCTCCACCGCTCGGCAGGCAGCGAGGACGG-3¢. The laneson the right ... activity of the Sp1/Sp3 interaction or the Sp1/Sp3/Ets-1 interaction byapproximately 90% and 80%, respectively. Mutation of the Ets-1 binding site (mut5) also blocked the effect of Ets-1 in the presence...
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Tài liệu Báo cáo khoa học: High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine pptx
... dependence for the turnover number (kcat) in the absence of excess substrate and for the turnover number (bkcat) in the presence of excess substrate, of the human BuChE mutant E197Q. The solid ... hydrogen bond between the protonated histidine and the carboxylate. In this way, the ability of the histidine to accept the proton from the serineOc is greatly increased. The presence of a short, stronghydrogen ... polarization of the C–O bond by the dipoles of the oxyanion hole in conjunction with the influence of aclose nucleophile like the Oc of the catalytic serine. The same type of adduct was observed previously...
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Tài liệu Báo cáo khoa học: "The Use of Shared Forests in Tree Adjoining Grammar Parsing" pptx
... since Gw is the lig shared forest the set VI is the set of the elementary node addresses of the object tag grammar Go. The set of final states, F, of MG,. is the set VT. The transition ... expect the symbol below the top of the stack to give us the node where 3 is adjoined. If r/is not on the spine of an auxiliary tree then it is the only symbol on the stack. We now show how the ... in the tag grammar is equivalent to deciding whether the shared forest cfg obtained generates the empty language or not. Each derivation of the shared forest cfg represents a parse of the...
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Báo cáo khoa học: Protein–protein interactions and selection: generation of molecule-binding proteins on the basis of tertiary structural information potx
... froma different species [23–25]. The success of the series of studies shows that the stable framework structure of Fv enables the transfer of function by means of CDRreplacement.Barbas et al. ... of the CDR 3 loop of antilysozyme VHHfunctionalized NCS without denaturation, although the thermal stability was decreased and the affinity forlysozyme was weaker than in the original VHH. The ... demonstrating the utility of the grafting of functional peptides with randomized edge sequencesfor optimizing the orientation of the grafted peptideon a scaffold protein. In addition, when the combina-tion...
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Báo cáo khoa học: Relationship between functional activity and protein stability in the presence of all classes of stabilizing osmolytes ppt
... published elsewhere. We havetherefore measured the thermodynamic parameters of RNase-A in the presence of these amino acids andamino acid derivatives, and values of DGD°, measuredin triplicate, ... those in the absence of sugars, i.e. Kmis decreased. On the otherhand, this change in conformation results in a decreasein kcat, the turnover number of the enzyme in the pres-ence of sugars, ... are coupled in the presence of anosmolyte. This study was undertaken to investigate the relationship between protein stability and activitychanges in the presence of a wide range of osmolytes.For...
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Báo cáo khoa học: Structure of the complex of a yeast glucoamylase with acarbose reveals the presence of a raw starch binding site on the catalytic domain doc
... the resolution of the native Glu structure, but has in addition revealed the presence of a second acarbose (substrate analogue)binding site on the surface of the enzyme, 25 A˚remotefrom the ... formedbetween the enzyme and Tris are the same as observedpreviously [16].In the Glu-A complex there are two acarbose mole-cules: one in the active site and the other on the sur-face of the enzyme ... accuracy, shows clearly the influence of cryo-cooling, which is manifested in shrinkage of the mole-cule and lowering the volume of the unit cell. In the structure of the com-plex, two acarbose...
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Báo cáo Y học: The presence of a helix breaker in the hydrophobic core of signal sequences of secretory proteins prevents recognition by the signal-recognition particle in Escherichia coli doc
... rely on the SecB pathway,because of overloading of the SRP pathway. The re-routing of (G-10L)prePhoE to the Sec translocon via the SRPinstead of the SecB pathway could be explained by the increased ... in the case of P48 cross-linked complexes and for WT prePhoE in the case of the TF cross-linked complexes. These amounts were set to 100%, and the relativecross-linking efficiencies of the other ... considered the possibility that extension of the a-helical structure in the signal sequence resulting from the Gly)10substitutionsaffects the targeting pathway of the precursor. Indeed, the mutations...
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Báo cáo khoa học: Evidence for the presence of ferritin in plant mitochondria pdf
... activation of the iron trans-port systems [37]. Therefore, they are crucial in controllingiron storage and homeostasis in the plant cells. Otherfunctions of plant ferritins are, on the other hand, ... other hand, the activity of cytochrome creductase, still detected in the presence of antimycin A,could depend on the presence of a similar enzyme on the outer membrane of plant mitochondria [27]. ... which were thensubjected to trypsin d igestion. The intensity of the immuno-labeled band was lower in the presence of the detergent,demonstrating that ferritin is localized inside the mito-chondrial...
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Gradual phase and morphology transformation of Fe3O4nanoparticles to a - FeOOH nanorods in alcohol/water mediain the presence of surfactant F127
... pentacarbonyl(Fe(CO)5) in the presence of oleic acid followed by oxi-dation [10], thermal decomposition of alkaline solution of Fe3+chelate in the presence of hydrazine [11], and directdecomposition of iron Cupferron ... for the synthesis of the Fe3O4nanoparticles, such as copre-cipitation of ferrous (Fe2+) and ferric (Fe3+) ions bybase [9], thermal decomposition of iron pentacarbonyl(Fe(CO)5) in the ... crystals. Inspired by the unique properties of the 1-D structure, much work has been concentrated on the synthesis of its nanorods [4, 5]. Fe3O4(magnetite), animportant member of spinel-type ferrite,...
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- these proteins direct the flow of information in the cell by activating
- the future of information technology
- this book provides information on the clinical relevance of blood groups and on the importance of blood group antibodies in transfusion medicine in particular
- so the amount of information
- the use of shared forests
- the structure of shared forests
- the representation of inconsistent information
- the role of information retrieval
- the structure of social and information networks
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