the presence of shared visual information

Ngày tải lên: 24/03/2014, 03:20

Ngày tải lên: 21/06/2014, 02:20

Ngày tải lên: 05/09/2013, 09:08

... of a-synuclein incubated alone (A), in the presence of 100 l M MPTP (B), in the presence of 200 lM MPTP (C), in the presence of 100 lM MPP + (D), in the presence of 200 lM MPP + (E), in the presence ... solu- tion of ThT and the fluorescence intensity of the solu- tion was measured at 482 nm. Figure 4A shows the kinetics of aggregation of a-synuclein in the presence of 100 lm MPTP and the effect of 50 ... 1B shows the pattern seen after the development of the blot. With increase in time of incubation, the intensity of the band for the monomeric protein decreased, whereas the bands for the higher...

Ngày tải lên: 14/02/2014, 19:20

... 3.5 From the point of view of economics, discounting means that the locally risk-free asset is chosen as the “num´eraire”, i.e. the prices of all other assets are evaluated in the units of this ... interpretation of the above definition is that g t is the number of units of the risk-free asset held in the portfolio at time t .The object h t (dT ) is interpreted as the “number” of bonds, with ... c t (E), and the equality is understood modulo λ c Q (t, dy), the image of the measure λ Q (t, dx) under the mapping c t . Since the right-hand side of (55) is a class of equivalence, the rigorous formulation...

Ngày tải lên: 16/02/2014, 02:20

... undetectable in the presence of Mn 2+ . The sol- vent-exposed C-terminus of VpUcyt probably pointed away from the surface of the micelle. The three amide cross-peaks originating from the hydrophobic ... of VpUcyt in detergent-free buffer con- firmed the absence of a secondary structure (Fig. 1). The presented data are the most comprehensive account of the lack of a conformational preference of VpUcyt ... probes 16-doxylstearic acid in the interior of the micelle (A) and Mn 2+ in the aqueous buffer (B) selectively attenuate distinct regions of VpU- cyt, reflecting the topology and the dynamics of the micelle-associ- ated...

Ngày tải lên: 18/02/2014, 06:20

... assay in the presence of stearate (Table 1). The good fit of Model III pro- gress curves to the experimental data supports the concept that in the presence of stearate the catalytic mechanism of plasmin ... parameters of plasmin in the presence of fatty acids. The values of k p and K m were determined from the amidolytic assay of plasmin activity, according to Model I, in the presence of oleate (OA) ... N is the total number of measurement points) is presented by the numbers in boxes. Fig. 3. Comparison of three models for the catalytic action of plas- min in the presence of stearate. The p-nitroaniline...

Ngày tải lên: 18/02/2014, 17:20

... minimize the FXa cofactor activity of the reaction intermediate, FVa int . This facilitated the determination of loss of FVa cofactor activity during the initial stage of inactivation and minimized the ... indicating that the stimulatory effect of heparin on the cleavage at Arg306 is also observed in the presence of FXa. Theoretically, the addition of heparin may induce the formation of a binary FXa–FXa ... phase of the reaction, as compared with inactivation in the absence of DEGR- FXa. Addition of 25 IUÆmL )1 UFH in the presence of DEGR-FXa stimulated the APC-mediated inactivation approximately twofold...

Ngày tải lên: 19/02/2014, 13:20

... that the constitutive expression of this gene is controlled by Ets-1 and requires the presence both of the Sp1 and Sp3 transcription factors. The presence of this complex multicomponent PRD in the ... indicates the nucleotide that is matched to the band present in the primer extension reaction on the right. The sequence of the primer is 5¢-CCTCCACCGCTCGG CAGGCAGCGAGGACGG-3¢. The lanes on the right ... activity of the Sp1/ Sp3 interaction or the Sp1/Sp3/Ets-1 interaction by approximately 90% and 80%, respectively. Mutation of the Ets-1 binding site (mut5) also blocked the effect of Ets-1 in the presence...

Ngày tải lên: 20/02/2014, 11:20

... dependence for the turnover number (k cat ) in the absence of excess substrate and for the turnover number (bk cat ) in the presence of excess substrate, of the human BuChE mutant E197Q. The solid ... hydrogen bond between the protonated histidine and the carboxylate. In this way, the ability of the histidine to accept the proton from the serine Oc is greatly increased. The presence of a short, strong hydrogen ... polarization of the C–O bond by the dipoles of the oxyanion hole in conjunction with the influence of a close nucleophile like the Oc of the catalytic serine. The same type of adduct was observed previously...

Ngày tải lên: 20/02/2014, 23:20

... since Gw is the lig shared forest the set VI is the set of the elementary node addresses of the object tag grammar Go. The set of final states, F, of MG,. is the set VT. The transition ... expect the symbol below the top of the stack to give us the node where 3 is adjoined. If r/is not on the spine of an auxiliary tree then it is the only symbol on the stack. We now show how the ... in the tag grammar is equivalent to deciding whether the shared forest cfg obtained generates the empty language or not. Each derivation of the shared forest cfg represents a parse of the...

Ngày tải lên: 22/02/2014, 10:20

... from a different species [23–25]. The success of the series of studies shows that the stable framework structure of Fv enables the transfer of function by means of CDR replacement. Barbas et al. ... of the CDR 3 loop of antilysozyme VHH functionalized NCS without denaturation, although the thermal stability was decreased and the affinity for lysozyme was weaker than in the original VHH. The ... demonstrating the utility of the grafting of functional peptides with randomized edge sequences for optimizing the orientation of the grafted peptide on a scaffold protein. In addition, when the combina- tion...

Ngày tải lên: 06/03/2014, 11:20

... published elsewhere. We have therefore measured the thermodynamic parameters of RNase-A in the presence of these amino acids and amino acid derivatives, and values of DG D °, measured in triplicate, ... those in the absence of sugars, i.e. K m is decreased. On the other hand, this change in conformation results in a decrease in k cat , the turnover number of the enzyme in the pres- ence of sugars, ... are coupled in the presence of an osmolyte. This study was undertaken to investigate the relationship between protein stability and activity changes in the presence of a wide range of osmolytes. For...

Ngày tải lên: 07/03/2014, 00:20

... the resolution of the native Glu structure, but has in addition revealed the presence of a second acarbose (substrate analogue) binding site on the surface of the enzyme, 25 A ˚ remote from the ... formed between the enzyme and Tris are the same as observed previously [16]. In the Glu-A complex there are two acarbose mole- cules: one in the active site and the other on the sur- face of the enzyme ... accuracy, shows clearly the influence of cryo-cooling, which is manifested in shrinkage of the mole- cule and lowering the volume of the unit cell. In the structure of the com- plex, two acarbose...

Ngày tải lên: 07/03/2014, 12:20

... rely on the SecB pathway, because of overloading of the SRP pathway. The re-routing of (G-10L)prePhoE to the Sec translocon via the SRP instead of the SecB pathway could be explained by the increased ... in the case of P48 cross- linked complexes and for WT prePhoE in the case of the TF cross- linked complexes. These amounts were set to 100%, and the relative cross-linking efficiencies of the other ... considered the possibility that extension of the a-helical structure in the signal sequence resulting from the Gly )10 substitutions affects the targeting pathway of the precursor. Indeed, the mutations...

Ngày tải lên: 08/03/2014, 09:20

... activation of the iron trans- port systems [37]. Therefore, they are crucial in controlling iron storage and homeostasis in the plant cells. Other functions of plant ferritins are, on the other hand, ... other hand, the activity of cytochrome c reductase, still detected in the presence of antimycin A, could depend on the presence of a similar enzyme on the outer membrane of plant mitochondria [27]. ... which were then subjected to trypsin d igestion. The intensity of the immuno- labeled band was lower in the presence of the detergent, demonstrating that ferritin is localized inside the mito- chondrial...

Ngày tải lên: 16/03/2014, 18:20

... pentacarbonyl (Fe(CO) 5 ) in the presence of oleic acid followed by oxi- dation [10], thermal decomposition of alkaline solution of Fe 3+ chelate in the presence of hydrazine [11], and direct decomposition of iron Cupferron ... for the synthesis of the Fe 3 O 4 nanoparticles, such as copre- cipitation of ferrous (Fe 2+ ) and ferric (Fe 3+ ) ions by base [9], thermal decomposition of iron pentacarbonyl (Fe(CO) 5 ) in the ... crystals. Inspired by the unique properties of the 1-D structure, much work has been concentrated on the synthesis of its nanorods [4, 5]. Fe 3 O 4 (magnetite), an important member of spinel-type ferrite,...

Ngày tải lên: 19/03/2014, 16:48

Ngày tải lên: 20/03/2014, 13:04

Ngày tải lên: 22/03/2014, 15:20