the nature of groups and its classification

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

Tài liệu Báo cáo khoa học: Modulation of a-synuclein aggregation by dopamine in the presence of MPTP and its metabolite pptx

... presence of 100 lM MPTP and 50 lM dopamine (F), in the presence of 200 lM MPTP and 50 lM dopamine (G), in the presence of 100 l M MPP + and 50 lM dopamine (H) and in the presence of 200 lM MPP + and ... a-synuclein was because of MPTP alone and not because of its con- version to MPP + , RP-HPLC of the samples was car- ried out. The incubated samples (a-synuclein alone and in the presence of 100 and 200 lm ... Figure 4A shows the kinetics of aggregation of a-synuclein in the presence of 100 lm MPTP and the effect of 50 lm dopamine on the aggregation process. Dopamine delayed the lag phase of aggregation...

Ngày tải lên: 14/02/2014, 19:20

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Tài liệu The Transformation of Banking and Its Impact on Consumers and Small Businesses docx

Tài liệu The Transformation of Banking and Its Impact on Consumers and Small Businesses docx

... way the growth of Internet banking and the combination of banking with other financial services, such as insurance and securities underwriting. The implications of these changes for the profitability ... broaden the array of products they offer online, making available services such as insurance and brokerage that they either produce themselves or market on behalf of other companies. As serious as these ... banks and branches for many of their banking services. Will the transformation of banking now under way hurt consumers by raising the price or reducing the quality of these services? Or will the...

Ngày tải lên: 16/02/2014, 11:20

29 498 1
the welding of aluminium and its alloys

the welding of aluminium and its alloys

... depend upon the composition, the quality and the grain size of the deposit.These in their turn depend on the parent and filler metal compositions, the amount of dilution, the quality of the welding ... conductiv- ity of aluminium and the consequent size of the area where there has been a substantial loss of strength.Only when the alloy is in the as-cast or annealed condition will the properties of the ... in the case of fusion welding above the melting point of the parent metals, and brought together to enable the components to coalesce. The heat of the welding operation is conducted into the...

Ngày tải lên: 12/03/2014, 17:32

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value and context the nature of moral and political knowledge oct 2006

value and context the nature of moral and political knowledge oct 2006

... Foot and Iris Murdoch in the 1950s. See Ethics and the Limits of Philosophy, 217–18 n. 7. The original target of the argument was the prescriptivism of R. M. Hare. ạ As Roger Crisp has noted the ... the part of the concept user. Overall, the point of the proposed two-factor analysis would be to prove that the two elements can be understood independently of each other. The point of the argument ... to cite the observed fact in both the explanation of the formation of the original belief, and also cite the same fact once again when we give our meta-level explanation of the processes of belief...

Ngày tải lên: 11/06/2014, 09:44

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Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt

Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt

... and quantitative real-time RT-PCR, the locations of the primers DN)105 and DN)9 used in ChIP assays, the locations of the primers DN+232 and DN+254 utilized in 5Â-RACE, and the locations of the ... fragments F and I. The number at the right of each RT-PCR product represents the length of the prod- uct. The scheme also shows the location of the reverse primer DN+89 used in another starting ... numbers over the diagrams indicate the position of the corresponding nucleotides relative to the translation start site, and the numbers in parentheses below the diagram show the position of the corresponding...

Ngày tải lên: 19/02/2014, 06:20

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Open Cultures and The Nature of Networks doc

Open Cultures and The Nature of Networks doc

... made audible the resonances between the blast of Dada at the end of WWI in Zurich and Berlin, the gust of the Situationists on the Rive Gauche in Paris in the 1960s, and the explosion of Punk Rock ... reduce the imbalances of power between the developer and the user, and between the rich and the comparatively poor. However, what the effects of this leveling of the playing field will be on other ... supporters of FOSS. For the time being, the low costs which increase its accessibility are offset by the still rather high barrier of technical expertise necessary to make use of the much of the software....

Ngày tải lên: 05/03/2014, 22:20

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Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

Báo cáo khoa học: N-Glycosylation is important for the correct intracellular localization of HFE and its ability to decrease cell surface transferrin binding pptx

... absence of tunicamycin. Drug treatments resulted in the accumulation of forms of the mutant proteins that were of lower apparent molecular mass and of similar size to the unglycosy- lated form of the ... each of the substrate asparagine residues can occur independently of the glycosylation status at the other two sites. A B Fig. 6. ER localization of the HFE-triple mutant and interaction of N-glycosylation ... that the two proteins are capable of interacting [33,34]. The nature of these interactions dif- fers from those observed between HFE and TfR1 in that they are mediated by the a3 domain of HFE,...

Ngày tải lên: 06/03/2014, 22:21

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Revealing the Hidden Nature of Space and Time: Charting the Course for Elementary Particle Physics pptx

Revealing the Hidden Nature of Space and Time: Charting the Course for Elementary Particle Physics pptx

... 5. The Secretary of Energy and the Director of the Na- tional Science Foundation, working with the White House Office of Science and Technology Policy and the Office of Management and Budget and ... suggests that these impending discoveries may transform our understanding of the origin of matter and energy and the ongoing evolution of the universe. The limitations of the Standard Model are ... did they see the final draft of the report before its release. The review of this report was overseen by Louis J. Lanzerotti of the New Jersey Institute of Technology and William Happer of Princeton...

Ngày tải lên: 14/03/2014, 10:20

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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx

Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx

... decrease of the amount of HIP-1–HIPPI heterodimer and apoptosis induction. The effect of HIP-1 may depend not only on the amount of the interacting proteins but also on the affinities of interacting ... model of HD [45]. The increased functional role of NMDAR in HD and the involvement of HIP-1 in NMDAR-mediated phos- phorylation of Htt [18] further indicate the possible participation of HIP-1 ... that of the mutated Htt [17]. In HD, one of the alleles of Htt is mutated and thus likely to release free HIP-1. Free HIP-1 then interacts with HIPPI through its C-terminal pDED domain and recruits...

Ngày tải lên: 23/03/2014, 07:20

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Báo cáo khoa học: Monitoring the prevention of amyloid fibril formation by a-crystallin Temperature dependence and the nature of the aggregating species pdf

Báo cáo khoa học: Monitoring the prevention of amyloid fibril formation by a-crystallin Temperature dependence and the nature of the aggregating species pdf

... by 0.0167 gặcm )3 , from the start of the experiment. By the end of the measurement, the thickness had increased by 0.342 nm, the mass had increased by 0.10 ngặmm )2 and the density had decreased ... interferome- ter, the AnaLight Bio200, which measures the mass, thick- ness and density of the protein layer bound to the surface of an optical sensor [35]. The sensing chip used in these a-Crystallin and ... fluores- cence. The subsequent plateau phase is associated with a decrease in the concentration of small species, or the aggregation and precipitation of fibrils [37]. The kinet- ics of these three stages of...

Ngày tải lên: 30/03/2014, 04:20

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wonderful life - the burgess shale and the nature of history

wonderful life - the burgess shale and the nature of history

... specimens reveal the crucial point of connection between the head appendages and the shield itself. (The end of the appendage opposite to the point of attachment with the body the distal, or farthest, ... division, with the entire organism (the part) on one surface, and only the impression (the counterpart) on the other. Any split must leave some pieces of the organism on one side, other bits on the opposite block. ... position of the eyes and nozzle, the full sequence of lateral lobes, and the gills lying above the lobes. The gut runs as a straight tube down the middle of the body. Figure 3.25 is a side view and reveals several...

Ngày tải lên: 08/04/2014, 00:54

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defending the society of states why america opposes the international criminal court and its vision of world society jul 2007

defending the society of states why america opposes the international criminal court and its vision of world society jul 2007

... ship carrying the flag of another country) at the moment of commission. As an indicator of the positivist nature of international law, the following passage from the Court’s opinion is often cited: International ... the case. Rejecting France’s claims, the PCIJ found that states were free to extend the application of their laws and the jurisdiction of their courts to persons, property, and acts outside their ... rules governing the relations of states, i.e. of individuals organized as a state. But this circumstance cannot affect decisively the moral content of international law and the dictates of reason and of the...

Ngày tải lên: 10/06/2014, 22:16

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state university of new york press darwin and the nature of species nov 2006

state university of new york press darwin and the nature of species nov 2006

... whether the species category is the subject of laws of nature is im- mediately shut off. If the species category is a set, then it cannot possibly be the subject of laws of nature because the ... formation of stars and planets, 22 DARWIN AND THE NATURE OF SPECIES rather the rapid overpopulation of Homo sapiens and the corresponding destruction of the environment. According to the best ... members of the cat- egory come and go in terms of existence. A group realist, on the other hand, cannot make this claim. As members of a group come and go in terms of existence, the definition of the...

Ngày tải lên: 11/06/2014, 12:55

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