the literary structure of the quranic verse

... Design of the Study The paper is designed in four chapters  Chapter one: The introduction – presents the rationale of the study, the aims of the study, scope of the study, methods of the study, ... Chapter three: The analysis of the text “Torquay?, but I said Turkey!” is aimed at the meanings and structures of the text  The last chapter: The conclusion – summarizes the results of the study ... called Theme and Rheme The Theme “served as the point of departure of the message” (Halliday 1994:37), which in English coincides with the initial element(s) of the clause; and the Rheme is the

Ngày tải lên: 07/09/2013, 13:48

... a theory of the quantum initial state of the universe (q.v.) and its consequences for observations today quantum initial state of the universe: sometimes called the wave function of the universe ... universe quantum of area: an elementary unit of area whose existence is predicted by the quantum theory of geometry (q.v.) quantum theory of geometry: a theory of the microscopic structure of ... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the

Ngày tải lên: 12/02/2014, 16:20

... the (door) the (ladder) the (planet) the (woman) her (arm) It she the (man) we the (air) It them their they the (plants) they they their the (man) the (controls) he I the ... describing the state of being of the things under the observation of the astronauts in the new planet. Most of the processes are in the simple past tense (25/36). They are used in the narrative ... 36 The spaceship The planet They There The spaceship The two astronauts The woman It She We It Both of them They All plants and Animals They They Everything The man

Ngày tải lên: 12/02/2014, 20:20

... (Leu104–Pro111) Indicative of the tightness of the fit, there are a large number (30) of atom-to-atom van der Waals’ contacts between the Tyr205 side chain and importin-a (Table 2) The numbers of contacts are ... competes for the importin-a binding site, reducing binding affinity for cargo proteins and helping to facilitate the release of the cargo within the nucleus [10,11] The removal of the autoinhibitory ... its location with the hydroxyl group reaching the importin-a main chain near the C-terminus of the ARM1 H3 helix Most of the hydrophobic contacts with importin-a residues lining the P4 pocket are

Ngày tải lên: 14/02/2014, 19:20

... molecules of the asymmetric unit of the wild-type structure Neither the mutation nor the different crystallization conditions evoked structural differences The crystal was grown in the presence of phytate, ... out of the catalytic pocket upon phytate binding Here, PhyK mimics the phytate-bound structure of AppA, even in the absence of sulfate ions The side chain of the corresponding Glu212 bends out of ... is the only direct contact between the protein backbone and the substrate The side chain of Thr292 is found to recognize the 2-phosphate in both the binding model of PhyK and the crystal structure

Ngày tải lên: 16/02/2014, 09:20

... mecha- nism of transphosphorylation, which implies the A B Fig. 3. Stereo diagram of the active center of HtA. (A) Superposition of the active-site residues of the 20 conformers of the solu- tion structure ... electrostatically with the other charged groups. In the NMR structures, this side chain of D40 is a short distance (£ 3A ˚ ) from the side chains of H42 and R95. Finally, the aromatic ring of F126, placed ... second- ary structure elements. As in other ribotoxins, these A B C Fig. 2. Representation of the 3D structure of HtA in solution. (A) Superposition of the 20 best structures obtained in this work (PDB

Ngày tải lên: 18/02/2014, 08:20

... occupy 16% of the molecular volume, and therefore seems too large to represent the lid-like structure at the top of the left view in Fig We speculate that the loosely structured region on the opposite ... of the PpNp The financial support of the Kultusministerium des Landes Sachsen-Anhalt and the Graduiertenkolleg 1026 of the Deutsche Forschungsgemeinschaft, Bonn (Germany), and the support of the ... ª 2007 The Authors Journal compilation ª 2007 FEBS 2637 Structure of plant phospholipase D S Stumpe et al from the ratio of the forward scattering intensity of the sample and that of the molecular

Ngày tải lên: 19/02/2014, 02:20

... arrangement, and the side chain of Ser97 in VPRK is too short One side of the loop is involved in the binding of the P2–P4 residues of a substrate The other side of the loop is close to Arg94 (Lys ... a residue forming a part of the S2 site of the enzyme The disulfide bridge restricts the flexibility of a tight loop which is part of the S2 site The tight loop is further stabilized by a tight ... the carbonyl oxygen atom of the scissile bond in other subtilase–inhibitor complexes (data not shown) The Ca positions of the tripeptide occupy almost the same positions as the Ca positions of

Ngày tải lên: 19/02/2014, 07:20

... because the dis- tances in this extended graph are based on the so- lution of the LP. The properties of this algorithm are given by the following two theorems (proofs in Appendix A). Theorem 2. The ... (2) The first summand accounts for the edges en- tirely within the region, and the second one ac- counts for the edges in C(v, r) to the extent that they are within the radius. The definition of ... v  ) otherwise, where P(u, v, E  ) denotes the set of acyclic paths between two nodes in E  . We further fix ˆc f =  (u,v)∈E  d(u, v) w(e) as the weight of the fractional solution of the LP (ˆc f is

Ngày tải lên: 20/02/2014, 04:20

... on the other hand involving the C-terminal part of the polypeptide chain (Fig. 7). In the latter, differences in the conformation of the loop between Fig. 6. Stereo picture of the model of the a-carbanion/enamine ... catalytic residues The active site cavity in IPDC extends from the thiazolium ring of the cofactor to the surface of the protein. The entrance of the active site cleft is covered by the C-terminal helix ... However, the packing of the two dimers in the tetramer is different from that of the PDCs of known structure, best described as a 20° rotation of one dimer towards the other when compared to the Z.

Ngày tải lên: 20/02/2014, 11:20

... superimposed on the X-ray structure (dark blue colour) and (B) structure alignment of the fragment 4–7 of the 13 ensemble structures of AII to the fragment 3–6 of the X-ray structure of AII Residue ... sequence and structure alignment Residue number range in the X-ray structure of AII Fig (A) Sequence alignment of the fragment 4–7 of the backbone of the 13 ensemble solution structures of AII (brown ... alignment of the two structures by using the program Profit1.8 Remarkably, the superposition of the solution state and the bound structure of AII exhibits small RMSD positional differences between the

Ngày tải lên: 20/02/2014, 23:20

... was used to back calculate the NOESY cross-peaks from the calculated structure to assess the quality of the structure. The final family was made up of 30 structures with the lowest target function. ... A ˚ , respectively, for the backbone of the two subunits. The difference between rmsd of monomeric and dimeric species is due to the indetermination of the reciprocal orientation of the two subunits. The average ... also similar t o the solution structure of the monomeric mutants with the exception of the s ignificantly better definition of the first part (49–63) of loop IV, which is disordered in the monomers

Ngày tải lên: 21/02/2014, 03:20

... the overall structure is shown in Fig 3A The enzyme exists as a dimer of the abc heterotrimer There is a noncrystallographic twofold axis around the center of Fig 3A The structure of an abc heterotrimer ... of the a subunit The substrate propane-1,2diol and essential cofactor K+ are bound inside the (b/a)8 barrel above the corrin ring of cobalamin K+ is heptacoordinated by the two hydroxyls of the ... irradiation [59] Therefore, we believe that the structure reported in this paper is also that of the glycerol dehydratascob(II)alamin complex The dihedral angle of the northern and southern least-squares

Ngày tải lên: 21/02/2014, 03:20

... established. Of two possible dimeric structures of LPL, the head-to- head and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL ... modeling of the dimeric structure of LPL. Two dimeric model structures of LPL were constructed using INSIGHT II version 2000 on a Silicon Graphics workstation. The model structure of the closed ... on the crystal structures of the human, porcine, and horse PLs (Fig. 1). A frontal view illustrates the overall saddle shape of the dimeric structure and the key heparin-binding residues in the

Ngày tải lên: 21/02/2014, 15:20

... for the N structure The G and TG structures were solved using the N structure as a search model, and the TG structure was used in phasing of the T structure The structures were refined using the ... typically increased the free R values by 0.1% Although the R and free R values of the four structures were in the range of the values of the published structures, those of the N and G structures were ... in the G and TG structures The electron density of l-glutamate became more pronounced upon the addition of Tris The location and orientation of l-glutamate were determined on the basis of the

Ngày tải lên: 06/03/2014, 09:22

... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... research, dedicated to the furtherance of science and technology and to their use for the general welfare Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a ... NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences,

Ngày tải lên: 06/03/2014, 15:20

... amide groups of Ile128 and Arg129. Despite these differences in the coordination of the res- idues in the tip, the fold of the loop is strikingly simi- lar. The rmsd for the Ca atoms of the residues ... conserved. The LL residues of the LLR sequence are important for the stability of the hydrophobic core below the ade- nine group. Fig. 8. A stereoview of the conformation shift of the KMSKS loop. In the ... inhibition of the enzyme. The pos- sibilities for design of a competitive inhibitor are also discussed. These structures exhibit a new structural feature of the CP domain. In one of the complexes, the

Ngày tải lên: 06/03/2014, 22:21

... bound than the M3 in MtSTP. Crystal contacts at the active site The differential occurrence of the metal ions correlates with the conformation of the flap subdomain (132–174) and the ‘binding’ of adjacent ... to the mechanism of the enzyme (see Discussion). Discussion Overall structure The structure of SaSTP is very similar to that of MtSTP, with an rmsd ⁄ Ca of 1.8 A ˚ overall (Table 1). All the ... and MtSTP, there are other clear differences in the TxSTP structure at the first two N-terminal helices, of which there are three in TxSTP. The helices are also longer. The major difference within the

Ngày tải lên: 07/03/2014, 09:20

... the ter- tiary structure of ApeSOD has not been elucidated. In the present study, for the first time, we describe the crystal structure of ApeSOD. In particular, we focus on the coordination of ... ligand, NE2 of His31, bound to the metal, in the company of a water oxygen, from the apical positions. The manga- nese was only 0.06 A ˚ out of the equatorial plane (Table 3). The angles around the metal ... metal cofactor. Figure 3D shows the superimposition of the active site structures of apo, Mn-bound and Fe-bound Ape- SODs. The most significant difference among them was related to the OH of Tyr39,...

Ngày tải lên: 14/02/2014, 22:20

... express ε AB R A43B in the form curl/π (2) + E (2) . 5. Strategy of the proof of the Asymptotics Theorem In this section we describe the main ideas in the proof of the Asymptotics Theorem. (1) Section ... given a detailed proof of the theorem by relying heav- ily on a result, which we have called the Asymptotics Theorem, concerning the geometric properties of the causal structure of appropriately ... I + 0 is the future domain of the origin on Σ 0 . Remark 9.3. The proof of Corollary 9.2 requires an extension argument. The estimates of the Asymptotics Theorem, which are uniform with respect to the...

Ngày tải lên: 16/02/2014, 05:20