... spherulin 3a and NKA48 contain only a single domain fold The stability of these two proteins is highly dependent on calcium binding [25] The typical domain motives contain a ‘tyrosine corner’ in the ... result of loss of induction at the transcriptional level, of loss of activation of the synthetase protein itself, or of derepression of enzyme(s) catalysing PMLA degradation An interesting interplay ... express a distinct fragmin-like actin-binding Cell type expression of spherulin 3b and polymalatase protein that controls in vivo phosphorylation of actin by the actin-fragmin kinase Eur J Biochem...
Ngày tải lên: 07/03/2014, 12:20
... might also be involved in intranuclear trafficking of the preintegration complex [20-23] In this study, we have tested the hypothesis that HDAC4 plays a role in the life- cycle of HIV-1-based ... Page of 10 Figure Effect of an integrase inhibitor on the formation of HDAC4 foci in infected cells HeLa cells were infected with the HIV-1-based vector in the presence and absence of the integrase ... observed the appearance of HDAC4 foci in infected cells, with the majority of cells containing foci at hrs post-infection (Figs and 3) Most of the infected cells contained multiple HDAC4 foci As indicated...
Ngày tải lên: 12/08/2014, 01:21
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES - Full cost accounting for the life cycle of coal potx
... life cycle of coal Epstein et al Table The life cycle impact of the U.S coal industry Economic Underground coal mining MTR mining Coal mining Human health Federal and state subsidies of coal industry ... in heavy coal mining areas of Appalachia, less so in light coal mining areas, lesser still in noncoal mining areas in Appalachia, and lowest in noncoal mining areas outside of Appalachia Another ... and qualitative costs of coal In order to rigorously examine these different damage endpoints, we examined the many stages in the life cycle of coal, using a framework of environmental externalities,...
Ngày tải lên: 23/03/2014, 00:20
Báo cáo y học: "Quality of life effects of antithrombin III in sepsis survivors: results from the KyberSept trial [ISRCTN22931023]" potx
... sepsis patients was used The risk intervals were identical to the SAPS II strata defined in the trial Outcomes Changes in quality of life between baseline and 90 days The Karnofsky scale and visual ... significantly more in the AT III subgroup than in the placebo subgroup not receiving heparin There was also a trend toward greater improvement in three other attributes in the no concomitant heparin subgroup, ... for other scales [12,13] The six domains of the first visual analog scale and the Karnofsky score are hereafter referred to as ‘attributes’ The clinical trial The KyberSept trial was a large, international,...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "The proteome of Toxoplasma gondii: integration with the genome provides novel insights into gene expression and annotation" potx
... accessed The option of refining the search to a single or combination of proteomic approaches, and of searching either annotated genes or ORFs, is available By adopting the GBrowse viewing Other ... analysis of Toxoplasma tachyzoites resulting in the identification of nearly one-third of the entire predicted proteome of T gondii and represents a significant advance in our understanding of protein ... transmission route of Toxoplasma By contrast, the sexual cycle, which results in the excretion of infectious oocysts in feces, takes place exclusively in felines The genome of Toxoplasma has been...
Ngày tải lên: 14/08/2014, 20:22
Báo cáo khoa học: " Vegetative development, primary and secondary growth of the shoot system of young Terminalia superba tropical trees, in a natural environment. I. Spatial variation" pot
... bands were wider in the former than in the latter (figs 4A, B) The staining of the wood background following the phloroglucinol-HCl test was less inlayers with wide band spacing than in those with ... 5B) These types of concentric and repeated variations - in the spacing of parenchyma bands and in the intensity of staining were not always closely correlated, especially in the lower trunk segments ... formation, especially the lack of rainfall, as in the wood of Carya glabra where the spacing of tangential parenchyma bands is related to the rate of rainfall (Hill, 1982) At any rate, the outer structural...
Ngày tải lên: 08/08/2014, 23:22
Báo cáo khoa học: "Vegetative development, primary and secondary growth of the shoot system of young Terminalia superba tropical trees, in a natural environment. II. Terminal growth, lateral growth and main stem-branch growth correlations" ppsx
... temporal aspects of the growth of young Terminalia superba trees in the same natural environment, including the lateral and radial growth of the tree In the present paper, shoot growth of main stems ... (fig 10) The cessation of radial growth and the beginning of branch shrinkage also coincided with the beginning of branching in a recently initiated tier (fig 9) Thus radial growth of branches ... internodes growing rapidly, continued by a slowgrowing vertical segment ending in a rosette of leaves In one of the trees studied, the accidental death of the main apex just after the initiation of a new...
Ngày tải lên: 08/08/2014, 23:22
Báo cáo y học: "Laboratory diagnosis of Toxoplasma gondii infection"
... G., Peruzzi S., Gorrini C., Chezzi C., Dettori G Evaluation of Toxoplasma gondii Immunoglobulin G (IgG) and IgM Assays Incorporating the New Vidia Analyzer System Clin Vaccine Immunol 2008; 15:1076–1079 ... 75-80 Contini C., Seraceni S., Cultrera R., Incorvaia C., Sebastiani A., Picot S Evaluation of a Real-time PCR-based assay using the lightcycler system for detection of Toxoplasma gondii bradyzoite ... of T gondii DNA on a small amount of 136 sample as it was in our experience (
Ngày tải lên: 03/11/2012, 11:01
Radionuclide behaviour in the natural environment docx
... outline basic principles of aquatic chemistry and water–rock interaction that determine the composition of natural waters and therefore influence the radionuclide behaviour in the natural environment ... non-existent in the natural environment Natural water, whether in the atmosphere, in the ocean, lakes and rivers, or below ground, always contains dissolved minerals and gases as a result of its interaction ... solubility product SP in logarithmic scale on the ordinate against the mol fraction XAC of the component AC in the solid and the activity fraction XAC-aq of the component AC in solution on the abscissa...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: " Porcine abortion outbreak associated with Toxoplasma gondii in Jeju Island, Korea" pot
... weeks) in the life of a cat, the enormous numbers shed assure widespread contamination of the environment [6] According to the system used to manage this herd, the pigs in individual rooms of the ... Studies aiming to clarify the sources of pig infection for T gondii have suggested that ingestion of oocysts in contaminated feed, water, soil, and living animals were the main sources of infection ... any stage of gestation The abortion rate was high (44%), and the mortality rate of the sows was 19% Intensive antibiotics including neomycin, gentamicin and cefazolin and symptomatic therapies...
Ngày tải lên: 07/08/2014, 23:22
Báo cáo sinh học: " Context-aware visual analysis of elderly activity in cluttered home environment" doc
... context The output of the TSVM classifier is further verified using zone-level context information Especially if the classifier output a lying posture, then the presence of the person in all inactivity ... applying accumulation of evidence are shown in the form of confusion matrix in Table The majority of the classifier errors occur during the transition of states, i.e., from sitting to standing ... for the inactivity zone learning In the case of intersection with activity zones, the assumed current sitting area B (candidate inactivity zone) is detected as false and ignored In case of no intersection,...
Ngày tải lên: 18/06/2014, 22:20
Báo cáo sinh học: "Second chromosome polymorphism of Drosophila buzzatii in a natural population is not associated with gametic selection and does not affect mating pattern" potx
... differential attraction of flies to the collecting baits; and iv), lack of selection in the laboratory (see Ruiz et al, 1986) In the present work we report the results of the analysis of the first assumptions, ... goodness of fit X tests The remaining individuals in the bottles were maintained until pupation in order to estimate larval viability by counting all pupae Further collections were performed in A ... analyses of larvae from the progeny of each wild inseminated female allowed us to assess the karyotype for the second chromosome of both parents assuming that the progeny of each female was fathered...
Ngày tải lên: 14/08/2014, 20:20
The human impact on the natural environment
... appearing within sight of the river, often resulting in significant openings in the wooded hillsides above and along the river In addition to the potential for added nonpoint water pollution reaching ... translate into the increasing need to address sustainable growth and development of the lower Connecticut River region The recognition of this area’s significance has not diminished; neither has the ... want to protect the wildlife and preserve the scenic areas along the river To preserve the natural settings they offer to buy your right to divide the property into smaller lots Since you had no...
Ngày tải lên: 10/06/2016, 16:16
Life cycle assessment (LCA) of an energy recovery plant in the olive oil industries
... the input of recycled materials to a product system is included in the data set without adding the data on environmental impacts caused in earlier life cycles In the waste case the environmental ... extraction of oil contained in dry pomace Before the extraction process, the process of distillation of the pomace oil separates the hexane from the oil and allows the sale of the pomace oil in the ... of Energy and Environment (IJEE), Volume 3, Issue 4, 2012, pp.541-552 Interpretation of the results In the assessment of the GHG savings of the bioenergy system, the definition of the fossil reference...
Ngày tải lên: 05/09/2013, 16:10
Báo cáo y học: " Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements" pot
... of the human APOBEC3 proteins [24,26,29] In addition, in silico analyses of the naturally present genomic copies of these elements in the murine genome have revealed "traces" of APOBEC3 editing ... impaired the in vivo amplification of these elements in the past, by searching for evidence of APOBEC3-editing on the endogenous copies residing in the murine and human genome, respectively Accordingly, ... depending on the eleFigure ment of the number of Variability of the number of G-to-A mutations within the endogenous IAPE-D and HERV-K proviruses depending on the element The total numbers of G-to-A...
Ngày tải lên: 13/08/2014, 05:21
Báo cáo y học: "Whole-genome analysis of mRNA decay in Plasmodium falciparum reveals a global lengthening of mRNA half-life during the intra-erythrocytic development cycle" pptx
... decapping Lsm1 PF11_0255† Involved in decapping Lsm2 PFE1020w Involved in decapping Lsm3 PF08_0049 Involved in decapping Lsm4 PF11_0524 Involved in decapping Lsm5 PF14_0411 Involved in decapping ... remodeling of the host cell in the ring stage The parasite then progresses into the trophozoite stage, where it continues to grow and is highly metabolically active Finally, in the schizont stage, the ... group and the increase in half -life from the ring to late schizont stage in Figure The decay rate progressively decreases in each stage for six of the ten groups Of the four remaining groups,...
Ngày tải lên: 14/08/2014, 07:22
characterisation of the acto-myoa motor complex in toxoplasma gondii
... subdomains form the ATP binding pocket, the barbed and pointed end of the monomer and serve as the binding site for actin-binding proteins Arps have a high homology to conventional actin with the ... recombinase in two inactive fragments Each of the fragments is fused to a rapamycin-binding protein (FRB and FKBP12) Addition of the ligand rapamycin results in dimerisation of the two inactive ... Toxoplasma gondii The life cycle in intermediate hosts is exclusively asexual and begins after oral uptake of oocysts Upon reaching the intestine, sporozoites are released and enter the epithelium of the...
Ngày tải lên: 22/12/2014, 19:37
Investigation of the role of the ubiquitin proteasome pathway in dengue virus life cycle 1
... infection in the midgut of the female mosquito after the ingestion of viremic blood Ingestion of an infected blood meal does not guarantee infection in the mosquito Upon ingestion, the virus encounters ... least two barriers: the midgut infection barrier (MIB) preventing infection of the mosquito midgut and the midgut escape barrier (MEB) preventing dissemination of the virus into the hemocoel (Kramer ... via the hemolymph to the other organs, such as the head, salivary glands and ovaries of the mosquito (Black et al, 2002) (Figure 1-10) In these organs, the infection is life- long and the continued...
Ngày tải lên: 09/09/2015, 08:20