the lc circuit and fourier analysis

... from the 1D spectrum 25% relative intensity in the STD spectrum Obviously, Pro1 and Asp2 get more saturation from the protein than the remaining residues of the ligand and therefore have more and ... less to the ligand The C-terminal part of the peptide (RPAP) has close contacts to the next protein in the crystal cell and is therefore stabilized on the surface of SM3 It is unclear whether this ... steps and overlaid to the PDTRP fragment of the ligand of the X-ray structure (RCSB PDB entry 1SM3) After small manual corrections, the ligands were docked into the binding site of SM3 using the...

Ngày tải lên: 21/02/2014, 15:20

... that there exists a real number X with the property 1) X8n 11 + as n -+ 00, then is m algebraic integer f o the class S, and X is algebraic and belongs ro the field o f THEOREM B The proof of Theorem ... PROPERTY OF THE SET OF NUMBERS OF THE CLASS S The result of Theorem A of this chapter can be improved in the sense that the hypothesis can be replaced by the weaker one (The closure of the set of ... QI a2 In other words, we have the two following theorems A THEOREM 61 b have real or complex elements Then a, then is an algebraic integer o the class S, and X is an algebraic number o the f f...

Ngày tải lên: 31/03/2014, 15:08

... Research & Therapy Vol No Matteson et al Bongartz T, Sutton AJ, Sweeting MJ, Buchan I, Matteson EL, Montori V: Anti-TNF antibody therapy in rheumatoid arthritis and the risk of serious infections and ... malignancies Systemic review and meta -analysis of rare harmful effects in randomized controlled trials JAMA 2006, 295:2275-2286 Stern R, Wolfe F: Infliximab dose and clinical status: results ... [http://www.remicade.com/global/ hcp/hcp_PI.jsp] Lagakos SW: Time-to-event analyses for long-term treatments: The APPROVe trial N Engl J Med 2006, 355:113-117 Page of (page number not for citation purposes)...

Ngày tải lên: 09/08/2014, 08:22

... mentioned The men, especially the husband and the grandfather, sip alcohol and tell their family members what they see and hear or remind them of right or wrong things in life The others also ... from the serving dishes and add them to the rice Then, they hold the rice bowl near their mouth, using their chopsticks to eat However, eating on the table sometimes is not easy as there are standards ... spoon on the right hand side and a fork on the left placed before each them Besides, the wine glasses are on the right, the salt cellar, the pepper box and mustard pot are in the middle of the table...

Ngày tải lên: 15/04/2013, 15:11

Ngày tải lên: 13/12/2013, 05:15

Ngày tải lên: 13/12/2013, 05:15

Ngày tải lên: 17/01/2014, 03:20

... characteristics of the Internet; , Ko and DIKo are defined as the average diameter, K, and DIK of the original networks and df , Kf and DIKf denote the diameter, K, and DIK after 10% of the nodes are ... popular node to others is one and the diameter between any two nodes except the most popular node is two, therefore the average diameter is less than two, and the network has the smallest diameter ... the Internet, and the BA and GE models under mixed failures after 10% of total nodes are destroyed (a): The average diameter of the Internet and the BA model increases rapidly compared with the...

Ngày tải lên: 18/02/2014, 01:20

... to their positions The arrowheads depict the residues important for the structural core of the IL-10 gene The underlined amino acid residues are the signal sequences of the respective genes The ... from carp, torafugu and human The x-axis denotes the residue position and the y-axis represents hydrophobicity The hydrophobicity analysis was carried out according to the Kyte and Doolittle method ... form the helices in the human IL-10 sequence show a degree of similarity to the carp IL-10 sequence The most highly conserved stretch in the IL-10 family is at the C-terminus in the C-helix and...

Ngày tải lên: 20/02/2014, 02:21

... orientation The program TURBOFRODO (Bio-Graphics, Marseille, France) was used to calculate the Ramachandran plot and perform the superposition of the models Electrostatic potentials were calculated and ... of the antigens to the column and purification of the antiserum were performed as described previously [28] Western blot analysis The specificity of the antisera was analysed by Western blot analysis ... A molecular surface [37] The inner and outer dielectric constants applied to the protein and the solvent were, respectively, fixed at 4.0 and 80.0, and the calculations were performed keeping a...

Ngày tải lên: 22/02/2014, 07:20

... individual diagnosis and therapy, and an understanding of the structure of these allergens is essential to the improvement of diagnosis and the design of adequate therapeutic treatment We previously ... to the N-terminal portion of the allergen Based on this partial sequence, two specific primers were designed and used together with the anchor primer AP2 to obtain the 5¢ and 3¢ portions of the ... sequence and sequence alignment of Cyn d 24 (A) Nucleotide and deduced amino acid sequences of Cyn d 24 The numbers on the right of the figure indicate the positions of the nucleotide sequence The...

Ngày tải lên: 07/03/2014, 12:20

... simplicity, and in line with the results from the other calculations, the 20.0 to Asp142 b The calculations were performed on the crystal structure of the Dl40N ... in the ÔupÕ position rows and shows that in the presence of the substrate, rotation of Asp142 towards Glu144 lowers the pKa of the latter by 0.8 pH units The calculated effects of the D140N and ... units, depending on the position of Asp142 and the calculation used Interestingly, the calculations also suggest that the magnitude of this effect is in part due to the presence of the negatively...

Ngày tải lên: 07/03/2014, 14:20

... proteins to the cytosol Here we confirm and extend earlier studies of these AAA-peroxins and give a further detailed functional analysis of their cassette structure and interaction The interaction ... N-terminal fragment and the first AAA-cassette of PEX6 (PEX6N + D1–GAL4-BD) Neither of the cassettes alone nor the two AAA-cassettes together or the N-terminal part together with the second cassette ... the binding sites of these two AAA-proteins to their different protein regions and elucidated the importance of ATP-binding to the two AAA-cassettes of Pex1p and Pex6p for their interaction The...

Ngày tải lên: 07/03/2014, 16:20

... development The data, analysis, and findings presented in the report represent the Task Force’s best understanding of the broad and constantly changing scope of the ICT sector and the use of ICT in the ... Finland, France, Germany, Greece, Italy, Ireland, Japan, Luxembourg, the Netherlands, New Zealand, Norway, Portugal, Spain, Sweden, Switzerland, the United Kingdom, the United States and the ... roadmaps from the past to draw on The rapid transformations in the technological and financing trends for ICTD are reflected in the analysis and findings of this report The findings represent the key...

Ngày tải lên: 15/03/2014, 19:20

... and the expulsion of the active cysteine complete the reaction Asp44 is positioned to stabilize and orient the binding of the substrate, and Tyr112, Glu205 (207 in HP-TenA) and Tyr47 assist the ... respectively, and one responsible for the coupling of the HMP and HET moieties, corresponding to ThiE (HP0843) [4] By contrast, the bacterium apparently lacks the genes devoted to the biosynthesis of the ... to see how the latter residue points into the active site in the former and in the opposite direction in the latter (B) Stereo view of a detail of the electron density map around the putative...

Ngày tải lên: 16/03/2014, 00:20

... in the substrate The comparisons used to calculate these DDGà values are shown in Fig The DDGà values (representing the difference in the activation energy of the glycosylation steps) were calculated ... isolate the DGà corresponding to energy of the hydrogen bond between residue 39 3-OH (/3), which was added to the energy of /4e /4a interactions was the and and Results and Discussion The induction ... PAGE Then, the soluble material of the induced bacteria was used in the purification of the mutant enzymes through hydrophobic and ion-exchange chromatography Isolation of the mutant enzymes was then...

Ngày tải lên: 16/03/2014, 18:20

... 2D gel electrophoresis and compared with the value calculated from the protein amino acid sequence A good correspondence of the experimentally determined pI of 6.1 and the theoretically deduced ... environment of the single Trp residue The contribution of Tyr fluorescence to the overall protein emission was calculated to amount to 45% and the Trp emission quantum yield 0.015 The low value of the quantum ... the formation of the Ag-NPA-1–retinol complexes, either the distance between the Trp residue and retinol is significantly longer than 1.5 nm or there is an unfavourable mutual orientation of the...

Ngày tải lên: 16/03/2014, 18:20

... of the gcGLUT gene (A) The 12 exons of the gcGLUT gene are shown as boxes Filled and open boxes indicate translated and untranslated regions, respectively The position of the start (ATG) and ... using the PROTPARS program of the PHYLIP package version 3.57c [15] Support for the inferred clades was obtained by bootstrap analysis from 1000 replications of the data set using the SEQBOOT and ... PstI and XbaI, and southern hybridization analysis using GT-cDNA2 as a probe Northern blot analysis Total RNA (20 lg) from different tissues was electrophoresed on 1% agarose/formaldehyde gels and...

Ngày tải lên: 17/03/2014, 03:20

... expansionary in the other countries: Austria, Belgium, Finland, Ireland, Spain and the Netherlands 40 ECONOMIC ASSESSMENT OF THE EURO AREA The agreement reached on the Stability and Growth Pact by the European ... from the CPB for the Netherlands and Paavo Suni at ETLA for Finland Other Institutes provided comments, and Ray Barrell from NIESR drafted the note 11 C.f footnote 11 ECONOMIC ASSESSMENT OF THE ... Spain, the Netherlands, Finland and Ireland Table 2.4 shows two estimates of the fiscal stance in the euro area, based on EUROFRAME-EFN forecasts for GDP growth and government deficits The assessment...

Ngày tải lên: 17/03/2014, 06:20

... out and was in complete agreement with the expected sequences The theoretical masses of the products TyrAAT1 and TyrAAT2 were determined to be 68.5 kDa and 36 kDa, respectively BLAST Fig Biosynthesis ... from the rst in frame ATG codon and P2 Then the resulting PCR NdeIBamHI DNA fragment was cloned into the plasmid pET21 a(+), yielding the plasmid pET21TyrAAT2 For both constructs, sequencing of the ... ỵ ẵSn m 2ị where V app and K app are the apparent Vm and Km values for m m one substrate at different xed value for the concentration of the second substrate and n is the Hill coefcient RESULTS...

Ngày tải lên: 17/03/2014, 11:20