the key role of molecular organisation

... in their semantic content, but lexically they select only one of these EPs as their KEY, we propose that the semantic properties of the arguments of the verb giefien (water) in example (1) of ... focussed on (some of) the theoretical assumptions upon which the achievement of such a goal can be based realistically A presentation of the technical details of the LKB implementation of the grammar ... Predicates In the spirit of the MRS-based analysis for the German verbs gieflen and fi,illen that we have presented above, we propose that the semantic properties of the arguments of one of the most...

Ngày tải lên: 17/03/2014, 22:20

... months - No reduction of the incidence of fractures - No reduction of the rate of falls or the incidence of fractures No effect of serum vitamin D3 level - No reduction of the fracture risk (OR ... moment of time to environmental constraints [28,32] It has been suggested that the specificity of the mechanism of falls in the elderly, particularly the impairment of postural reactions - either ... an abnormality of processing of musculoskeletal mechanisms and of sensorimotor information in the CNS The central question is to determine whether the age-related alteration of the postural adaptation...

Ngày tải lên: 19/06/2014, 08:20

... [12, 29] They all highlight the effect of the summer drought on soil respiration and some of them also show the negative effect of the cold temperature in winter on respiration Two types of measurements ... till the end of the experiment, the treatment effect was highly significant (P < 0.001) The plot effect was only significant in July 1999 due to the high heterogeneity of data in the C plots The ... efflux The model ‘Temp’ explained only 6% of the variance of the soil efflux and 23% for the ecosystem respiration Introducing soil moisture in the two other model allows us to better describe the...

Ngày tải lên: 08/08/2014, 01:21

... results obtained by other groups who also point to the role of the connecting loop of the b-hairpin of defensins A combination of mutational analysis [35] and structural analysis of the plant defensin ... accessible residues charge of the b-hairpin loop, as compared with that of other domains of the molecule, might be a key feature for the activity of defensins It must be noted that the a-helix (residues ... plotted against the log of the measured MIC The aforementioned results showed that synthetic peptides corresponding to fragments of the MGD1 defensin reproduced the behaviour of the entire molecule...

Ngày tải lên: 20/02/2014, 11:20

... infer function of the protein Confirm transmission of the phenotype and map it Identify the mutation, and thereby prove importance of the gene to the phenomenon Practical application of forward and ... effector limb of the response During the decade of the 1980s, one of the key discoveries in sepsis research concerned the role played by soluble mediators of monocyte/macrophage origin in shock ... However, it is the cellular response to microbes that creates the septic syndrome, and a handful of specific receptors alert the host to the presence of an infection The effector limb of the response...

Ngày tải lên: 12/08/2014, 19:21

... attempts, the ‘hands-off’ intervals between interruption of chest compressions and the delivery of the countershock should be limited to only a few seconds [8,20] In all of these areas of concern, ... ventricular fibrillation is one of the greatest causes of premature mortality in many societies, the magnitude of the public health impact of AEDs is potentially dramatic, in terms of both life-saving and ... summary, the use of AEDs by the average person may be considered one of the greatest advances in critical care medicine during the past decade Similarly, recent technology has also enhanced the quality...

Ngày tải lên: 12/08/2014, 23:21

... doctrine of the party as the leader of the proletarian revolution, a privileged status that is legalized in constitutions that grant the party the role of exclusive representative of the population ... restated by the 1992 constitution: The Communist Party of Vietnam, the vanguard of the Vietnamese working class, the faithful representative of the rights and interests of the working class, the toiling ... and positive role in establishing democratic regimes The discussion of the role of mass mobilization in democratic transitions is often associated with the study of the emergence of “civil society,”...

Ngày tải lên: 16/10/2015, 15:35

... largely inaccessible for evaluation of the fetus and of the fetal testis, even if study of the mother (her 16 Male Reproductive Health Disorders and the Potential Role of Environmental Chemical Exposures ... some of the weaknesses and problems that can affect the quality of studies investigating the potential causes of cryptorchidism and hypospadias Quality assessment of the various studies and of the ... limitations on the scope of this review Two overviews are used to set the scene for the review First, an assessment of the latest evidence on the prevalence of human TDS disorders and whether this...

Ngày tải lên: 13/02/2014, 10:20

... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA Conservation of spacing is required for optimal promoter activity because changing the ... However, as in most other CDE ⁄ CHR promoters, mutation of the CHR results in a smaller remaining cell cycle-regulation than alteration of the CDE [37] Interestingly, the core of the human Tome-1 ... promoters, mutation of the CHR leads to a more pronounced deregulation than the alteration of the CDE [40] Another gene tested for its cell cycle regulation is the cellular inhibitor of apoptosis protein...

Ngày tải lên: 16/02/2014, 09:20

... cost-effective way of assessing health risks; • the identification of all risk points along the chain of events from the origin of the wastewater to the consumption of the produce (e.g the farm-to-fork ... personal-care products and pharmaceuticals The impacts of these are wide-ranging In the north east of Australia, run-off of agricultural herbicides caused the loss of 30 km2 of mangrove between 1999 and 2002 ... for the increasing volume of wastewater that we produce are at the heart of the wastewater crisis The way we produce our food uses 70–90 per cent of the available fresh water, returning much of...

Ngày tải lên: 17/02/2014, 10:20

... intermediate [11] The sum of these ndings points at the involvement of more than one active oxidant in the diverse types of P450-catalyzed substrate processing [1215] The goal of the present perspective ... which small alterations in the environment can cause drastic changes in the reactivity of the active species [76] Further support in favour of the idea of the involvement of a high-valent iron-oxene ... those of the gross molecular motions of many enzyme-bound substrates and depending on the stereochemical specicities of the compounds to be acted upon [16,17] Reduction of ferric P450 to the ferrous...

Ngày tải lên: 19/02/2014, 16:20

... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... and the 1970s saw tremendous swings from the latter to the former, setting the stage for another swing of the pendulum back to the latter as a result of disappointments with the results of diffuse ... members of the committee on the field visits and who provided general guidance to the committee greatly enriched the quality of the report: Michael Clegg, Foreign Secretary of the National Academy of...

Ngày tải lên: 05/03/2014, 12:20

... appropriate, the CAQ formed a task force on the role of the auditor and moved to convene investors and other financial reporting stakeholders to examine the role of the auditor and the value of the audit ... isolation The “what, whys, and hows” related to changing the role of the auditor has to be considered within the context of the overall financial reporting system, including the important roles of the ... evolve the role of the auditor to meet the needs of investors in the near and longer term In the near term, the CAQ and its member firms have developed model reports for the PCAOB and other stakeholders...

Ngày tải lên: 15/03/2014, 20:20

Ngày tải lên: 18/03/2014, 11:22

Ngày tải lên: 23/03/2014, 05:23

... reasonable to assume that the disruption of the H-bond makes the distal His less basic As a consequence the pKa value of the NeH of the distal His is lowered and the rate constant for the reaction with ... Reinheitszahl of Asn153fiAsp These spectral data together with the kinetic parameters presented below suggest that the mutations caused no significant changes in the interactions of the heme with the apoprotein ... inspection of the crystal structures of members of the plant, fungal and bacterial superfamily show the existence of a hydrogen bond between the distal His and an Asn (Fig 1) [3–5] The corresponding...

Ngày tải lên: 23/03/2014, 21:20

... rise of the internet and the spread of McDonalds to the establishment of the International Criminal Court and the emergence of global terrorism Focusing on the implications of globalization for the ... Interesting from the view of diplomacy is the aim of UCLG to gain an official status at the UN in order to promote and protect the interests of cities worldwide in all of the issues with which the UN deals ... the role of cities in diplomacy We would like to thank the city of The Hague for its sponsorship of the project We would also like to extend our gratitude to the interviewees for dedicating their...

Ngày tải lên: 24/03/2014, 21:20

... share of the euro in the bond portfolios of large international fund managers, on the one hand, and the rising share of the euro in the stock of international bonds, on the other Looking ahead, the ... international role of the euro, Frankfurt am Main ECB (2002), Review of the international role of the euro, Frankfurt am Main ECB (2003a), The international role of the euro: main developments since the ... importantly, in the course of the past few years, the ECB has put in the limelight three major traits that characterise how the international role of the euro has unfolded so far The first is that the euro’s...

Ngày tải lên: 29/03/2014, 06:21

... mutants of the MetAP-I from E coli S Mitra et al affect the DG value for the binding of the rst metal ion; however, the entropic factor (TDS) for the binding of the rst metal ion decreases in the ... values of 90 20, 210 100 and 574 150 lm The heat of reaction, measured during the experiment, was converted into other thermodynamic parameters using the Gibbs free energy relationship The thermodynamic ... that allows the concentrations of the titrant and the sample to be tted to the heat-ow-per-injection to an equilibrium binding equation for two sets of noninteracting sites The Ka value, the metalenzyme...

Ngày tải lên: 30/03/2014, 02:20

... challenging than for the other oligosaccharides, due to the poor dispersion of signals in the 3.2–4.1 p.p.m region of the spectra Although the 1H signals of the anomeric protons of the 2951lgt5 ⁄ 4D ... to obtain the 13C shift of the C1 and C2 resonances of Kdo Examination of the 400 ms NOESY spectrum confirmed each of the glycosidic linkages for the 2951lgt1 ⁄ 4D oligosaccharide and the terminal ... elucidate the 13C shift of the C1 and C2 resonance of Kdo For the highly branched, central a-d-Glc residue C, the locations of the H3 ⁄ C3 and H5 ⁄ C5 correlations were conspicuous in the 1H-13C-HSQC...

Ngày tải lên: 30/03/2014, 08:20