the involvement of o glcnacase oga in insulin signaling
Tài liệu Báo cáo khoa học: Characterization of human deoxyribonuclease I gene (DNASE1) promoters reveals the utilization of two transcription-starting exons and the involvement of Sp1 in its transcriptional regulation ppt
Ngày tải lên :
19/02/2014, 06:20
... that of pGL3–promoter vector These findings demonstrate the promoter activity of the 5¢-flanking region of exon in DNASE1 Deletion of the upstream end of the 5¢-flanking region of exon from position ... characterization of the promoter region of the gene and the associated transcriptional factors Therefore, delineation of the transcriptional Promoters of human deoxyribonuclease I gene regulation of human ... exons 2–9, which contain the entire coding region Thus, use of alternative promoters in DNASE1 results in no generation of protein isoforms The 5¢-UTR of eukaryotic mRNA in uences the initiation...
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Báo cáo khoa học: Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response potx
Ngày tải lên :
07/03/2014, 21:20
... (putrescine, spermidine and spermine) through conversion of l-arginine into l-ornithine [16] The latter is in turn used by ODC to produce putrescine, the precursor of spermidine and spermine To further ... enzyme involved in the polyamine synthesis pathway through the catalysis of l-ornithine production from l-arginine Of the natural polyamines, spermine and to a lesser extent spermidine, possess ... also participate in the LPS-mediated or H pylori-mediated induction of ArgII via a TLR-4-dependent pathway The role of polyamines in apoptosis is controversial; both induction of and protection...
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Báo cáo khoa học: The involvement of human ribonucleases H1 and H2 in the variation of response of cells to antisense phosphorothioate oligonucleotides pot
Ngày tải lên :
08/03/2014, 10:20
... perinuclear and cytoplasmic staining of other structures than appear following liposomal transfection The corresponding PO-ODN shows a similar pattern and intensity as the PS-ODN in the ¯uorescent ... of the role of RNase H2 in the PSODN mediated cleavage of target mRNA in vivo requires some additional knowledge On the one hand, the components binding to this enzyme need to be identi®ed to ... the in vivo and in vitro measurements could be due to a compartmentalization of a component in the in vivo system On the other hand, we cannot exclude the possibility that the substantial amount...
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Báo cáo sinh học: " The involvement of survival signaling pathways in rubella-virus induced apoptosis" ppt
Ngày tải lên :
18/06/2014, 22:20
... response in the cell following RV infection and that signaling downstream of MEK1/2 is required for RV replication, growth and induction of apoptosis Analysis of phosphorylation profiles during ... activation during the early stages of infection in vitro, prior to the appearance of morphological apoptotic changes [6] The importance of PI3K survival signaling has been observed with other viruses ... increase in the speed and magnitude of RV-induced apoptosis To evaluate the role of PI3K-dependent signaling during RV infection, the effects of PI3K inhibitor LY294002 on the development of RV-induced...
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báo cáo hóa học: " Effects of betaine on lipopolysaccharide-induced memory impairment in mice and the involvement of GABA transporter 2" doc
Ngày tải lên :
19/06/2014, 22:20
... 23 Glowinski J, Iversen LL: Regional studies of catecholamines in the rat brain I The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain J Neurochem ... spent exploring any one of the two familiar objects (familiarization session) or the novel object (retention session) over the total time spent exploring the two types of objects An exploratory preference ... involving inflammatory processes and oxidative stress; however, the effects of betaine on memory impairment involving neuroinflammatory and/or oxidative stress are not well known Therefore, the...
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Báo cáo y học: "MLN51 and GM-CSF involvement in the proliferation of fibroblast-like synoviocytes in the pathogenesis of rheumatoid arthritis" pps
Ngày tải lên :
09/08/2014, 08:23
... cytokines or other factors together with GM-CSF in the SF may be involved in RA pathogenesis in vivo To address the effects of GM-CSF in SF on the growth of RA FLSs, we cultured the RA FLSs in ... immunization with heterologous or autologous type II collagen of rat, bovine or chick CII origin [32] In addition, DCs are particularly relevant in the pathogenesis of most inflammatory arthropathies ... microenvironments To identify factors having an effect on the growth of RA FLSs, we investigated the inflammatory cytokines and growth factors on the growth of RA FLSs (2–14) in vitro The results indicated...
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báo cáo khoa học: "Is the involvement of opinion leaders in the implementation of research findings a feasible strategy?" doc
Ngày tải lên :
11/08/2014, 05:21
... professional groups and sites in the extent of nominating SOLs and the complexity of networks Furthermore, this has been one of the first studies to examine whether opinion leaders are polymorphic ... polymorphic or monomorphic Responses to the sociometric instruments demonstrated a wide variation across different professional groups and sites in the extent of nominating SOLs and the complexity of social ... Gynaecologists Oncologists Total respondents Mean score of all respondents (SD) Range of scores of all respondents (SD) Total SDOLs Mean score of selfdesignating opinion leaders (SD) Range of scores...
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báo cáo khoa học: " The Arabidopsis pop2-1 mutant reveals the involvement of GABA transaminase in salt stress tolerance" pps
Ngày tải lên :
12/08/2014, 03:21
... to induction of the gene in shoots GUS staining pattern of NaCl-treated roots seemed to be more complex GUS staining was indeed sharply reinforced in the terminal Renault et al BMC Plant Biology ... (D-E) Focus on root apices visible in B and C (F-G) Focus on areas under white boxes visible in B and C Arrows point to primary root nutrition of plant suggesting involvement of this isoform in nitrogen ... analysis of metabolite profiling data Samples plot on the first two principal components (PCs) is shown (C-D) Comparison of metabolite levels in WT and pop2-1 roots (C) and shoots (D) Only metabolites...
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báo cáo khoa học: " Transcriptional responses to polycyclic aromatic hydrocarbon-induced stress in Arabidopsis thaliana reveal the involvement of hormone and defense signaling pathways" pdf
Ngày tải lên :
12/08/2014, 03:21
... Hypocotyl length of d old Arabidopsis seedlings grown in absence or presence of phenanthrene in the dark Top: Mean root lengths with standard error bars Bottom: Response (%) is the ratio of root ... triiodobenzoic acid (TIBA), brassinolide, cytokinin, the auxin indoleacetic acid, the gibberellic acid biosynthesis inhibitor paclobutrazol (PAC), the ethylene precursor ACC, and the inhibitor of ... Figure b: Overview of photosynthesis; Figure c: Overview of carotenoid biosynthesis; Figure d: Overview of protein targeting; Figure e: Overview of cellular responses; Figure f: Overview of gene...
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Báo cáo y học: "The increase of plasma galectin-9 in a patient with insulin allergy: a case report" ppt
Ngày tải lên :
13/08/2014, 13:22
... from those of other markers The relative ratios were calculated as the fold change value of each inflammatory marker/fold change of the eosinophil count (Eosino#) Page of Figure The levels of ... (Figure 1) The levels of inflammatory markers against the eosinphil counts are shown using the fold change in Figure The profile of the relative ratios against the eosinophil counts in GAL-9 was ... Heubi JE, Putnam PE, Rothenberg ME: Potential of blood eosinophils, eosinophilderived neurotoxin, and eotaxin-3 as biomarkers of eosinophilic esophagitis Clin Gastroenterol Hepatol 2006, 4:1328-1336...
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Studying on the actual status of the vegetation cover and the process of natural forest recovery in Vi Xuyen district, Ha Giang province (Nghiên cứu hiện trạng thảm thực vật và quá trình phục hồi rừng tự nhiên ở huyện Vị Xuyên, tỉnh Hà Giang)
Ngày tải lên :
19/09/2014, 09:45
... 105 Note: Microor of phosphate resolution; Microor of cellulose resolution; Microor .of nitrogen fixation; Microor creating mucous membranes Ord 17 From the results in Table 4.21, it can take the ... 4.2.7 The change of characteristics of soil profiles in the vegetation cover types - Of all four types of vegetation covers studied, soil profiles consist of layers A, B and C In the forest restoration ... province The results of analysis of soil samples in vegetation cover types in Table 4.23 shows that the composition of soil microorganism groups includes namely: 18 + The group of bacteria includes...
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The use of warm-up activities in speaking lessons in Yen Lang High School a case study = Việc sử dụng các hoạt động tiền dạy nói trong giờ dạy nói ở THPT Yên Lã
Ngày tải lên :
30/03/2015, 14:30
... motivated, they are eager to participate in classroom activities and volunteer to perform them 1.3.2.2 Introducing the topic of the lesson Introducing the topic of the lesson is one of the most ... 2003) According to Nunan, communication in speaking can be expressed into two ways: information routine and interaction routine In information routine, only speakers provide information For example, ... very important goals of WAS The findings from the frequency of purposes of WAS and the importance of the goals of WAS showed that the importance of the goal decided the frequency of use 1.4 Difficulties...
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The roles of rac1 and syncollin in regulated exocytosis insulin secreting INS 1 cells as a model
Ngày tải lên :
16/09/2015, 17:11
... chronic hyperglycemia, which results from a failure of the body to release adequate amounts of the blood glucose-lowering hormone insulin, from the inability of the target organs to respond to insulin ... glucose intolerance develops The insulin secretory abnormalities in type diabetes include the rise of fasting insulin levels and the loss of the first phase of insulin secretion in response to ... (GAPs) increase the rate of hydrolysis of bound GTP, resulting in inactivation of G-proteins The guanine nucleotide dissociation inhibitors (GDIs) bind the inactive form of Gproteins and retain them...
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The involvement of cellular components in west nile virus replication cycle
Ngày tải lên :
16/09/2015, 17:13
... of flavivirus envelope protein (a) Diagrams of the flavivirus ectodomain and transmembrane domain proteins The volume occupied by the ectodomain of an E monomer is pink (domain I), yellow (domain ... responsible for nuclear localization of the C protein The purpose of localizing flavivirus C protein in the cell nucleus during virus replication is currently not known Since the introduction of ... was initiated by the release of cytochrome c from the mitochondria and accompanied by the formation of apoptosomes In turn, this led to the activation of caspase-9 and -3, and to the cleavage of...
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A study to investigate the involvement of nadph oxidase 5 (NOX5) in resveratrol (RSV) induced reactive oxygen species (ROS) production in u937 cells
Ngày tải lên :
26/09/2015, 10:44
... NOX inhibitor DPI Tiron abrogates the production of O2 .- ions Inhibiting the production of O2 .- ions would deter the progressive formation of other ROS species Catalase converts the H 2O2 produced ... participates in amino acid transport through the plasma membrane protecting them from oxidation Peroxiredoxins (PrX) form another another group of enzymes that are involved in the decomposition of H 2O2 ... formation of other forms of ROS species NOX enzymes are one of the major sources of ROS NOX5 belongs to the family of NOX enzymes NOX5 differs from the other members of the NOX family in aspects...
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The Organization of Local Government Administration in Japan (Tổ chức chính quyền địa phương ở Nhật Bản)
Ngày tải lên :
06/12/2016, 16:14
... overseas dissemination of information on the local governance system of Japan and its operation” On the basis of the recognition that the dissemination to overseas countries of information on the Japanese ... regard to the former of the two proposals outlined here, namely removal of the obligation to establish a board of education and its replacement by the right of local government to choose, no work ... indication of the source Contact Council of Local Authorities for International Relations (CLAIR) (The International Information Division) Sogo Hanzomon Building 1-7 Kojimachi, Chiyoda-ku, Tokyo...
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The Duality of Memory and Communication in the Implementation of a Multiprocessor Operating System
Ngày tải lên :
12/09/2012, 15:05
... no assumptions about the purpose of the memory object In order to make memory object data available to tasks in the form of physical memory, the Mach kernel acts as a cache manager for the contents ... CPUs in the Butterfly is by means of a Butterfly Switch, the complexity of which increases only as the logarithm of the number of processors The Butterfly makes no use of cache memory and remote ... implemented on a range of architectures Today, the concept of an extensible operating system is once again gaining acceptance this time as the solution to the unconstrained growth of UNIX During the...
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Equivalence in the translation of vietnamese cultural words in the book “wandering through vietnamese culture” by huu ngoc
Ngày tải lên :
07/11/2012, 14:31
... but the nominal sense of the words is noting to the end of the book Stepping into the land of one to part of one equivalence, which happens when a English expression could only covers part of ... group of people, the consistency of the translation from the beginning of the book to the end of the book is crucial This helps avoid the misunderstanding that two translated versions of the same ... items and the translation of nominal group 2.2.2 Other types of equivalence In the second part of the chapter, the writer of this thesis would set the aim to look into less common types of equivalence...
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