... promoters, mutation of the CHR leads to a more pronounced deregulation than the alteration of the CDE [40]. Another gene tested for its cell cycle regulation is the cellular inhibitor of apoptosis protein ... If the DREAM complex is the main regulator of CDE ⁄ CHR cell cycle genes, to which promoter sites does it bind during any par- ticular phase of the cell cycle? What is the exact mechanism of ... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA. Conservation of spacing is required for optimal pro- moter activity because changing the...
Ngày tải lên: 16/02/2014, 09:20
... for the History of Medicine, the University of Michi- gan, the University of Pittsburgh, the Cleveland Clinic, the New York Consortium for the History of Medicine at the New York Academy of Medicine, ... Universities of Aberdeen and Edinburgh; the Royal College of Physicians of Edinburgh; the Royal College of Surgeons of Edinburgh; the Royal College of Physicians and Surgeons of Glasgow; the National ... or the Conjunction, or finally the Chances, of experiment. None of these however extend so far as the invention of any axiom (Bacon, 1875c, p. 413). The investigator of nature goes about gathering...
Ngày tải lên: 07/03/2014, 04:20
The chart shows the number of mobile phones and landlines per 100 people in selected countries ppsx
Ngày tải lên: 07/07/2014, 12:20
Báo cáo sinh học: "The nature of cell-cycle checkpoints: facts and fallacies" docx
... specific for the different phases of the cell cycle and determine the targets of the kinases. Exit from each phase of the cell cycle occurs on degradation of the bound cyclin. The CDK-cyclin ... be generated. On the other hand, correction of the other type of erroneous attach- ments, merotelic, does not generate unattached kineto- chores - which is why the presence of merotelic attach- ments ... other pathways that respond to everything from the status of p53 or p38 to the integrity of the chromosomes and DNA catenation? First off, some of these claims fail to consider that multiple...
Ngày tải lên: 06/08/2014, 19:21
báo cáo khoa học: "PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture" ppsx
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: " On the steps of cell-to-cell HIV transmission between CD4 T cells" pptx
Ngày tải lên: 12/08/2014, 23:22
Báo cáo y học: " A statistical approach to estimating the strength of cell-cell interactions under the differential adhesion hypothesis" pptx
Ngày tải lên: 13/08/2014, 16:21
A CFD analysis on the effect of ambient conditions on the hygro-thermal stresses distribution in a planar ambient airbreathing PEM fuel cell
Ngày tải lên: 05/09/2013, 14:58
The Use of Plant Cell Biotechnology for the Production of Phytochemicals
... elucidation of specific biosynthetic enzymes, and the identification of end-products. The complete genetic makeup of an organism has been generated in the plant sciences as well. Because of the success of ... made in plant cell cultures of C. roseusby Dos Santos et al. (1994) concerning equality of the rate of catabolism with the rate of de novo compound biosynthesis. The phenomenon of catabolism ... of interest or the feasibility of the bioprocess. A number of factors may contribute to the efficiency of plant cells to produce desired compounds. Genetic stability of cell lines, optimization of culture...
Ngày tải lên: 25/10/2013, 05:20
Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf
... confirmed the active role of miR-23a in the growth promotion of malignant cells. The fundamental function of miRNAs is to regulate their targets by direct cleavage of mRNA or by inhibi- tion of protein ... further studies. Collectively, our studies demonstrate that miR-23a potently promotes the growth of the gastric adeno- carcinoma cell line MGC803, providing the first proof- of- concept that there ... with the 3Â UTR of target genes. Further- more, the 2–8 nucleotides of miRNA, known as the ‘seed region’, have been suggested to be the most important region for target recognition [16]. Therefore, we...
Ngày tải lên: 18/02/2014, 04:20
Tài liệu The Age of Invention, A Chronicle of Mechanical Conquest pdf
... day write. They include the epic of the coal in the Pennsylvania hills, the epic of the ore, the epic of the railroad, the epic of the great city; and, in general, the subjugation of a continental ... PIONEERS OF THE MACHINE SHOP IX. THE FATHERS OF ELECTRICITY X. THE CONQUEST OF THE AIR BIBLIOGRAPHICAL NOTE THE AGE OF INVENTION The Legal Small Print 6 hand. The owners of the mills are particularly ... seamstresses, gathered under one roof, laboriously sewed garments together, but the great bulk of the work, until the invention of the sewing machine, was done by the wives and daughters of farmers...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx
... that cell volume fluctuations release signals of (patho)physiological relevance. The understanding of how cell swelling integrates into the cell cycle machinery and how cell shrinkage sensitizes cells ... H4IIE rat hepa- toma cells to pro-apoptotic signaling by the protea- some inhibitor MG-132 [40]. These and other studies on hyperosmotically shrun- ken cells support the view that the apoptotic volume decrease, ... apoptotic stimuli requires further scientific effort. Cell hydration may markedly affect the action of drugs. For example cell hydration changes may switch the outcome of proteasome inhibitors from...
Ngày tải lên: 18/02/2014, 16:20