the igf axis in the development and progression of prostate cancer

Báo cáo khoa học: Comparative proteomic analysis identiﬁes proteins associated with the development and progression of colorectal carcinoma pot

Ngày tải lên : 23/03/2014, 03:20

... over-expression of the three proteins was signiﬁ- cantly associated with the genesis and progression of CRC. The functional implications of the alterations in the levels of these proteins are discussed in ... proteins both in vitro and in vivo [11,12]. They also inhibit nucleotide exchange and GTP-hydrolyzing activities on Rho proteins by interacting with their switch regions and probably restricting ... proteins involved in protein synthesis and folding (heat shock proteins), cell communication and signal transduction (annexin), cellular reorganization and the cytoskeleton (tropo- myosin, tubulin...

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báo cáo hóa học:" The positive mental health instrument: development and validation of a culturally relevant scale in a multi-ethnic asian population" pdf

Ngày tải lên : 20/06/2014, 15:20

... led the team. EA led the statistical and psychometric analyses. MOE guided, trained and performed the psychometric analyses and interpreted the findings. LP led the field work and training of interviewers ... reliability of the instrument in Singa- pore and other Asian and Western cultures. Acknowledgements This study was funded by the Singapore Millennium Foundation and the Ministry of Health, Singapore. Author ... to both the statistical parameters and impact on the final instru ments’ content, ta king into account the phrasing of the items and their meaning. 1. Exploratory factor analysis (EFA): The s ample...

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INTENSIVE LIFESTYLE CHANGES MAY AFFECT THE PROGRESSION OF PROSTATE CANCER docx

Ngày tải lên : 29/03/2014, 01:20

... strength of evidence. While the evidence linking the effects of diet and lifestyle on the development and progression of prostate cancer is not conclusive, it is hardly meager. A wide body of evidence ... the progression of prostate cancer, including significant reductions in low den- sity protein cholesterol and weight. Cardiovascular disease is the leading cause of death of men and women in ... blinded to group assignment. Baseline equivalence of the 2 groups was analyzed using the independent sample t test in the case of continuous variables and the chi-square test of association in...

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Báo cáo lâm nghiệp: "in leaf development and thesis of Prunus serotina seedlings" doc

Ngày tải lên : 09/08/2014, 04:20

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costs and effectiveness of prostate cancer screening in elderly men potx

Ngày tải lên : 01/04/2014, 13:20

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Báo cáo khoa học: Altered expression of tumor protein D52 regulates apoptosis and migration of prostate cancer cells potx

Ngày tải lên : 30/03/2014, 02:20

... role in prostate cancer development and progression [21]. Because the precise mechanism of the function of TPD52 in prostate cancer progression is still under investigation, the main objective of ... tissue [31]. The expression of several genes, such as CARD10 [32] and Vav3 [33], and integrins is important in determining the formation of metastatic cells [34,35]. The expression of murine TPD52 in ... examined to deter- mine the role of TPD52 expression in prostate cancer. Results A protein proﬁling study on prostate biopsies identi- ﬁed differentially expressed proteins in cancer contain- ing...

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Rural and Micro Finance Regulation in Ghana: Implications for Development and Performance of the Industry ppt

Ngày tải lên : 22/03/2014, 21:20

... coordination between the Ministry of Finance, BOG and the Ghana Microfinance Institutions Network (GHAMFIN) has led to a better understanding of the characteristics of microfinance loans and the ... collection of the required level of savings, and they continue to save into their individual accounts as they repay the loan. The group handles the collection of savings and repayments, acts as the interface ... kinds of institutional providers of microfinance and, especially, their development into self- sustaining, commercial microfinance institutions capable of reaching growing numbers of poor...

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Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx

Ngày tải lên : 18/06/2014, 16:20

... practical in the setting of a clinical study, the final assay protocol included a two hour incu- bation period in the presence or absence of Ab-01. This protocol mimicked the conditions of the intended ... and lack of efficacy due to ineffective dosing by providing early clinical data on how well the drug hits the target in vivo, and on the best dosing regimen to maintain target engagement/inhibi- tion. ... variety of lymphoid and non-lymphoid cells including fibroblasts and intestinal epithelial cells [16-18]. The activities of IL21 have been shown to be highly dependent on the lineage of the target...

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báo cáo hóa học: " Development and validation of a preference based measure derived from the Cambridge Pulmonary Hypertension Outcome Review (CAMPHOR) for use in cost utility analyses" doc

Ngày tải lên : 18/06/2014, 19:20

... 1 [26,27]. It is interesting to note that in the development of the EQ-5D the state of perfect health was not valued and was assumed to be 1 [19]. This anchoring meant that in the PH validation ... were combined into four domains such that two domains had three levels and the other two domains had two levels. The items were selected by re-analysis of the responses of 201 patients to the CAM- PHOR ... and contributed to the writing of the manuscript. JB designed and managed the valuation survey, analysed and reported on the valuation data and contributed to the writing of the manuscript....

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báo cáo hóa học: " Development and validation of a French patient-based health-related quality of life instrument in kidney transplant: the ReTransQoL" pot

Ngày tải lên : 18/06/2014, 19:20

... time Most of time A good bit of the time Some of the time A little of the time None of time 35 Is taking medications a constraint for you? 36 Are you scared of the possible side effects of the anti-rejection ... study and its design, coordinated the data management, analyzed and interpreted the data, drafted the manuscript; EJ participated in the design of the study, collected the data and performed the ... to pay the printing of question- naires, mailing costs, data management and the English translation of the draft. References 1. Spiker BN: Quality of life and phamarcoeconomics in clinical trials....

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báo cáo hóa học: " Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" docx

Ngày tải lên : 18/06/2014, 22:20

... conceptualisation and design of the original web-based survey. FJS, SES and FP assessed the quality of the data collected and participated in the design of the validation study and the development of the statistical ... striking. Yet, still 36% of the insulin-treated patients agree to the item that injecting insulin is painful, compared to 43% in the insulin-naïve group. This sug- gests that despite improved injection ... insulin-treated agreed that insulin causes weight gain, compared to 23% in the insulin naïve. The highest mean score for insulin-naïve patients was on the item pertaining to the belief that insulin...

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báo cáo hóa học:" Development and validation of the insulin treatment appraisal scale (ITAS) in patients with type 2 diabetes" pdf

Ngày tải lên : 20/06/2014, 16:20

... conceptualisation and design of the original web-based survey. FJS, SES and FP assessed the quality of the data collected and participated in the design of the validation study and the development of the statistical ... striking. Yet, still 36% of the insulin-treated patients agree to the item that injecting insulin is painful, compared to 43% in the insulin-naïve group. This sug- gests that despite improved injection ... insulin-treated agreed that insulin causes weight gain, compared to 23% in the insulin naïve. The highest mean score for insulin-naïve patients was on the item pertaining to the belief that insulin...

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Báo cáo khoa học nông nghiệp " The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - MS2 " potx

Ngày tải lên : 21/06/2014, 06:20

... Capacity Building The major focus of the project at this stage has been the training of DARD officers from Ninh Thuan, Binh Thuan and Lam Dong provinces in goat husbandry and management, in the conduct ... meeting in Dalat in Lam Dong, and plans for the coming year discussed with the collaborating team. The first official visit will be made to the farms in Lam Dong and will be the focus of a ... production and increasing small-holder income in the central region of Vietnam (009/05VIE) in Vietnam during the period January to June 2006. Funding was first provided following the official signing...

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Project Progress Report: The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - MS3 " doc

Ngày tải lên : 21/06/2014, 06:20

... Building The major focus of the project at this stage has been the training of DARD officers from Ninh Thuan, Binh Thuan and Lam Dong provinces in goat husbandry and management, in the conduct ... will include the final outcome of the technological innovations on the productivity and well-being of Vietnamese goat farmers in these areas. Objective 2. Training and Information Dissemination ... overcome, thereby improving the income and well-being of farming communities in these areas. The following report presents information collected on the Goat Production Baseline (Output 1.1, 1.2 and...

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The development and implementation of new appropriate technologies for improving goat production and increasing small-holder income in the central region of Vietnam - Milestone 9" pot

Ngày tải lên : 21/06/2014, 06:20

... findings from project activities, including analysis and interpretation of farming system surveys carried out in 2006 and 2008, and of the biology and productivity of goats following the introduction ... workshop training manuals, evaluation of competency of staff training and a survey of farmers views of the sustainability of the technologies introduced will all be presented in the Milestone ... improving productivity will be overcome, thereby improving the income and well-being of farming communities in these areas. The following report (Milestone 9) is a comprehensive description of the...

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the development and adoption of legal normativedcuments by state administrative agencies in the people’s democratic republic of laos

Ngày tải lên : 17/07/2014, 20:11

... qualification of the staff of the Ministry of Justice is mainly in law and politics, not in other disciplines. There is no female staff. The majority of staff are in the age group of 30 to 50. ... capable, and of professional qualification satisfying requirements for the development and completion of laws in the framework of administrative reform, and development of a socialist state of law. ... directions of the Party and State of the People’s Democratic Republic of Laos on legal development, including the development and adoption of legal normative documents, together with the research of...