the gravitational equations and the problem of motion

Tài liệu Báo cáo khoa học: Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase pdf

Tài liệu Báo cáo khoa học: Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase pdf

... reduces the pep- tide binding affinity by 100-fold and the lifespan of the complex by 10-fold, as judged by k off . The physiological chaperone cycle probably consists of the rapid binding of the ... hypothesize that the proton- ated state of the chaperone initiates this cycle, whereas the deprotonated state occurs upon completion of the maturation process of the partner. The nature of the signal ... common feature of this new family of chaperones. It is worth mentioning that the function of these proteins is not restricted to the recog- nition and binding of the N-terminus of the nascent metalloprotein,...

Ngày tải lên: 16/02/2014, 14:20

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Tài liệu A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco pptx

Tài liệu A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco pptx

... capable of giving strength to the weary, vivacity to the stupid, and wisdom to men void of understanding; capable of soothing the sorrows of the afflicted, of healing the wounds of the spirit, and ... healthy condition of the vessels belonging to the membranes of the socket, with the condition of which, the state of the tooth is closely connected."] Having gone through with an examination of the physical ... towards them. Hence the Methodists interdicted the common use of tobacco with that of ardent spirit, in the infancy of their society; thereby evincing a just sense of the self-denial, decency, and...

Ngày tải lên: 17/02/2014, 22:20

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Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx

Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx

... Superposition of the active-site residues of the 20 conformers of the solu- tion structure of HtA. Catalytic groups E66 and H113 are shown in red, and side chains of other residues in their vicinity ... understanding the structural requirements for the general ribonucleolytic and cytotoxic activities of the protein HtA. With this aim, we determined the structure of HtA by 1 H-NMR methods, and the ... Comparison of the spatial orientation of the N-terminal b-hairpin and loops 2 and 5 in HtA and a-sarcin. The backbone trace is represented in blue for the b-hairpin, orange for loop 5, and green...

Ngày tải lên: 18/02/2014, 08:20

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Tài liệu Regulatory Rights Supreme Court Activism, the Public Interest, and the Making of Constitutional Law doc

Tài liệu Regulatory Rights Supreme Court Activism, the Public Interest, and the Making of Constitutional Law doc

... of the Constitution to judicial decisions about the text, theorists insist that the warp and woof of constitutional law is still traceable to the written document and must be, given that the ... try again (and again and again) to succeed where they and others have failed before. My aim is primarily to organize the argu- ments and counterarguments and to expose the pretense of a documen- tary ... fed- eral and state governmental power) associated with the Due Process Clauses of the Fifth and Fourteenth Amendments and the Equal Protec- tion Clause of the Fourteenth. But I also turn to the freedom...

Ngày tải lên: 18/02/2014, 11:20

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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx

Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx

... ligand binding. The loop region of the upper domain moves towards the active site of the enzyme, thus shielding the substrates (and ligands) from bulk solvent. A detailed thermodynamic study of ... 1UAE [11]), conformation. The thiol group of C115 is highlighted in green and the nitrogen atoms of R120 and K22 in blue. The open form of MurA is unliganded (A) and the closed conformation (B) ... importance of R120 for the formation of the covalent fosfomycin adduct, we construc- ted the K22V/R120V and K22V/R120K double mutants (see Materials and methods) and repeated the analysis of adduct...

Ngày tải lên: 19/02/2014, 13:20

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Tài liệu The Golden Mean and the Physics of Aesthetics pdf

Tài liệu The Golden Mean and the Physics of Aesthetics pdf

... the notions of extended tuning systems, the relation of tuning to timbre and spatiality of sound, and the concentration of attention for extended time periods.” One may also generalize the ... romantic idea that in the golden ratio “is contained the fundamental principle of all formation striving to beauty and totality in the realm of nature and in the field of the pictorial arts.” ... bursting with false claims and misconceptions about the appearance of the Golden Ratio in the arts (e.g. in the works of Giotto, Seurat, Mondrian). The history of art has nevertheless shown that artists...

Ngày tải lên: 19/02/2014, 17:20

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Tài liệu Báo cáo khoa học: "An Implemented Description of Japanese: The Lexeed Dictionary and the Hinoki Treebank" ppt

Tài liệu Báo cáo khoa học: "An Implemented Description of Japanese: The Lexeed Dictionary and the Hinoki Treebank" ppt

... the semantic classes C for both the head- word (w i ) and hypernym(s) (w g ). If at least one of the index word’s classes is subsumed by at least one of the genus’ classes, then we consider the ... familiar- ity and part of speech, all the underlined features are those added by the Hinoki project. 3 The Hinoki Treebank The structure of our treebank is inspired by the Redwoods treebank of English ... Entry for the Word doraib ¯ a “driver” (with English glosses) grammar in tandem with the treebank, as part of our research into natural language understanding. Treebanking the output of the parser...

Ngày tải lên: 20/02/2014, 12:20

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Tài liệu The Social Benefits and Economic Costs of Taxation doc

Tài liệu The Social Benefits and Economic Costs of Taxation doc

... or other characteristics beyond the control of the country’s government, by the method used to aggregate individual indicators, by the com- parability of the data, and by the purpose of the ... indication of the lack of economic freedom in the compila- tion of the index, the average score of the Nor- dic countries on the overall economic freedom index is only slightly higher than that of the ... positions in the professions, legislative bodies, and senior civil service. In contrast to the United States, Finland ranks near the top of the industrialized world on each of the following...

Ngày tải lên: 20/02/2014, 19:20

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Tài liệu The Choctaw Freedmen and The Story of Oak Hill Industrial Academy ppt

Tài liệu The Choctaw Freedmen and The Story of Oak Hill Industrial Academy ppt

... amount of land or personal property, the ability to read and write the constitution of the state or of the United States, and the "Grandfather Clause" which permits one unable to meet the ... enjoyment of the fruits of his own labor and the pursuit of happiness in his own way, as long as he walks in the path of rectitude and duty and does not trespass upon the rights of others," ... choice of electors for president and vice-president of the United States, representatives in congress, the executive and judicial officers of a state, or the members of the legislature thereof,...

Ngày tải lên: 21/02/2014, 08:20

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Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx

Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx

... migrating bands of three LPS (without R14) and fast migrating bands of P. mirabilis G1, O 28, and R14 LPS (Fig. 5A). These bands correspond to high- and low-molecular-mass LPS species consisting of the ... migrating bands of all LPS tested and slow migrating bands of P. mirabilis S1959, G1, and O28 LPS, the banding patterns being clearly different (Fig. 5B). These findings together showed that the epitope ... O-polysaccharide p art of LPS. The serological relatedness of P. mirabilis G1 and S 1959 correlated with the similarity of the chemical structures of their O-polysaccharides (Fig. 3). Therefore, it is...

Ngày tải lên: 21/02/2014, 15:20

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Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx

Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx

... RPAP. The size o f the interaction surface between the peptide and the non binding bottom of the Fab is 173 A ˚ 2 which c orresponds to about 36% of the interaction of the full peptide with the ... MUC-1; binding epitope. The extracellular part of the epithelial glycoprotein MUC-1 consists of tandem repeats of 20 amino acids (PDTRPAPGSTAPPAHGVTSA, where the start of the tandem repeat peptide ... e crystalcellthathaveadistanceof4A ˚ or less to the ligand. The C-terminal part of the pe ptide (RPAP) has clo se contacts to the n ext protein in the crystal cell and is therefore stabilized on the surface o...

Ngày tải lên: 21/02/2014, 15:20

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Tài liệu The Majors of Golf Complete Results of The Open, the U.S. Open, the PGA Championship and the Masters, 1860–2008 pdf

Tài liệu The Majors of Golf Complete Results of The Open, the U.S. Open, the PGA Championship and the Masters, 1860–2008 pdf

... The Majors of Golf Complete Results of The Open, the U.S. Open, the PGA Championship and the Masters, 1860–2008 MORGAN G. BRENNER Volume 1 (Introduction; Abbreviations; The Open; ... 3 Part I. The Tournaments 7 The Open Championship 9 U.S. Open Championship 200 • Volume 2 • Professional Golfers Association of America Championship 397 Masters Tournament 518 Part II. The Players, ... 94 88 182 34T Anderson, William A. 96 87 183 20 1891 / The Open Championship PART I. THE TOURNAMENTS Pos Player A R1 R2 R3 R4 Tot P/M W This page intentionally left blank TABLE OF CONTENTS •...

Ngày tải lên: 22/02/2014, 08:20

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ADVANCING THE HEALTH, SAFETY, AND WELL-BEING OF OUR PEOPLE pdf

ADVANCING THE HEALTH, SAFETY, AND WELL-BEING OF OUR PEOPLE pdf

... ADVANCING THE HEALTH, SAFETY, AND WELL-BEING OF OUR PEOPLE The Department of Health and Human Services enhances the health and well-being of Americans by providing for effective health and human ... and security, standards and interoperability, public health, research and evaluation, technical assistance and funding for the National Institute of Standards and Technology. The HITECH ... Aging…………………………………………………………………… 86 Office of the Secretary General Departmental Management………… ……………………………………… 89 Office of Medicare Hearings and Appeals………………………… …………………. 91 Office of the National Coordinator...

Ngày tải lên: 05/03/2014, 13:20

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A Joint Publication of the Office of the Attorney General and the Department of Business and Economic Development docx

A Joint Publication of the Office of the Attorney General and the Department of Business and Economic Development docx

... Maryland and federal law regulate the use of ―child labor‖ (i.e., the employment of persons below the age of eighteen) and the employment of people to do work in their homes. The Maryland Division ... but the business goals of the venture may be accomplished in any of these formats. III. MERGERS UNDER MARYLAND LAW One last example of the flexible options offered by Maryland law is in the ... Division, Office of the Attorney General David M. Lyon, Principal Counsel, Office of the Attorney General, Department of Assessments and Taxation Craig A. Nielsen, Principal Counsel, Office of the...

Ngày tải lên: 06/03/2014, 21:20

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Báo cáo khoa học: Functional association of the AAA complex and the peroxisomal importomer potx

Báo cáo khoa học: Functional association of the AAA complex and the peroxisomal importomer potx

... interestingly, in contrast with the lack of other components of the peroxisomal protein import machinery, the deficiency of Pex4p does not interfere with the assembly of the components of the importomer. In ... a control. The corresponding solubilisates (right panel) were analyzed for the presence of Pex1p and Pex6p as indicated. The defici- ency of either protein of the AAA peroxin couple in the absence of ... cytosol. The specifity of the precipitation is confirmed by the lack of detection of the abundant proteins Fbp1p and thiolase in the eluates (data not shown). Figure 1B shows a compar- ison of the cytosolic...

Ngày tải lên: 07/03/2014, 12:20

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