the gravitational equations and the problem of motion
Tài liệu Báo cáo khoa học: Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase pdf
Ngày tải lên :
16/02/2014, 14:20
... reduces the pep-
tide binding affinity by 100-fold and the lifespan of the
complex by 10-fold, as judged by k
off
. The physiological
chaperone cycle probably consists of the rapid binding
of the ... hypothesize that the proton-
ated state of the chaperone initiates this cycle, whereas
the deprotonated state occurs upon completion of the
maturation process of the partner. The nature of the
signal ... common feature of this new
family of chaperones. It is worth mentioning that the
function of these proteins is not restricted to the recog-
nition and binding of the N-terminus of the nascent
metalloprotein,...
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Tài liệu A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco pptx
Ngày tải lên :
17/02/2014, 22:20
... capable of giving strength to the weary, vivacity to the stupid, and wisdom
to men void of understanding; capable of soothing the sorrows of the afflicted, of healing the wounds of the
spirit, and ... healthy
condition of the vessels belonging to the membranes of the socket, with the condition of which, the state of
the tooth is closely connected."]
Having gone through with an examination of the physical ... towards them.
Hence the Methodists interdicted the common use of tobacco with that of ardent spirit, in the infancy of their
society; thereby evincing a just sense of the self-denial, decency, and...
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Tài liệu Báo cáo khoa học: Solution structure of hirsutellin A – new insights into the active site and interacting interfaces of ribotoxins docx
Ngày tải lên :
18/02/2014, 08:20
... Superposition of the active-site
residues of the 20 conformers of the solu-
tion structure of HtA. Catalytic groups E66
and H113 are shown in red, and side chains
of other residues in their vicinity ... understanding the
structural requirements for the general ribonucleolytic
and cytotoxic activities of the protein HtA. With this
aim, we determined the structure of HtA by
1
H-NMR
methods, and the ... Comparison of the spatial orientation
of the N-terminal b-hairpin and loops 2 and
5 in HtA and a-sarcin. The backbone trace is
represented in blue for the b-hairpin, orange
for loop 5, and green...
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Tài liệu Regulatory Rights Supreme Court Activism, the Public Interest, and the Making of Constitutional Law doc
Ngày tải lên :
18/02/2014, 11:20
... of the Constitution to judicial decisions
about the text, theorists insist that the warp and woof of constitutional
law is still traceable to the written document and must be, given that
the ... try again (and again and again) to succeed where they
and others have failed before. My aim is primarily to organize the argu-
ments and counterarguments and to expose the pretense of a documen-
tary ... fed-
eral and state governmental power) associated with the Due Process
Clauses of the Fifth and Fourteenth Amendments and the Equal Protec-
tion Clause of the Fourteenth. But I also turn to the freedom...
- 274
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- 1
Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
Ngày tải lên :
19/02/2014, 13:20
... ligand binding. The loop region of the upper domain
moves towards the active site of the enzyme, thus shielding
the substrates (and ligands) from bulk solvent. A detailed
thermodynamic study of ... 1UAE [11]), conformation. The
thiol group of C115 is highlighted in green and
the nitrogen atoms of R120 and K22 in blue.
The open form of MurA is unliganded (A) and
the closed conformation (B) ... importance of R120 for the
formation of the covalent fosfomycin adduct, we construc-
ted the K22V/R120V and K22V/R120K double mutants
(see Materials and methods) and repeated the analysis of
adduct...
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Tài liệu The Golden Mean and the Physics of Aesthetics pdf
Ngày tải lên :
19/02/2014, 17:20
... the notions of extended tuning systems, the
relation of tuning to timbre and spatiality of sound, and the concentration of attention for
extended time periods.”
One may also generalize the ... romantic idea that in
the golden ratio “is contained the fundamental principle of all formation striving to
beauty and totality in the realm of nature and in the field of the pictorial arts.” ... bursting with false
claims and misconceptions about the appearance of the Golden Ratio in the arts (e.g. in
the works of Giotto, Seurat, Mondrian). The history of art has nevertheless shown that
artists...
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Tài liệu Báo cáo khoa học: "An Implemented Description of Japanese: The Lexeed Dictionary and the Hinoki Treebank" ppt
Ngày tải lên :
20/02/2014, 12:20
... the semantic classes C for both the head-
word (w
i
) and hypernym(s) (w
g
). If at least one of
the index word’s classes is subsumed by at least
one of the genus’ classes, then we consider the ... familiar-
ity and part of speech, all the
underlined features
are those added by the Hinoki project.
3 The Hinoki Treebank
The structure of our treebank is inspired by the
Redwoods treebank of English ... Entry for the Word doraib
¯
a “driver” (with English glosses)
grammar in tandem with the treebank, as part of
our research into natural language understanding.
Treebanking the output of the parser...
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Tài liệu The Social Benefits and Economic Costs of Taxation doc
Ngày tải lên :
20/02/2014, 19:20
... or other characteristics beyond the control
of the country’s government, by the method used
to aggregate individual indicators, by the com-
parability of the data, and by the purpose of the ... indication of
the lack of economic freedom in the compila-
tion of the index, the average score of the Nor-
dic countries on the overall economic freedom
index is only slightly higher than that of the ... positions
in the professions, legislative bodies, and
senior civil service.
In contrast to the United States, Finland ranks
near the top of the industrialized world on each
of the following...
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Tài liệu The Choctaw Freedmen and The Story of Oak Hill Industrial Academy ppt
Ngày tải lên :
21/02/2014, 08:20
... amount of land or personal property, the ability to read and write the constitution of the state or of
the United States, and the "Grandfather Clause" which permits one unable to meet the ... enjoyment of the fruits of his own labor and the pursuit of happiness in his own way, as
long as he walks in the path of rectitude and duty and does not trespass upon the rights of others," ... choice of electors for president and vice-president of the United States,
representatives in congress, the executive and judicial officers of a state, or the members of the legislature
thereof,...
- 216
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Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx
Ngày tải lên :
21/02/2014, 15:20
... migrating bands of three LPS
(without R14) and fast migrating bands of P. mirabilis
G1, O 28, and R14 LPS (Fig. 5A). These bands correspond
to high- and low-molecular-mass LPS species consisting of
the ... migrating bands of all
LPS tested and slow migrating bands of P. mirabilis S1959,
G1, and O28 LPS, the banding patterns being clearly
different (Fig. 5B). These findings together showed that the
epitope ... O-polysaccharide p art of LPS.
The serological relatedness of P. mirabilis G1 and S 1959
correlated with the similarity of the chemical structures of
their O-polysaccharides (Fig. 3). Therefore, it is...
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Tài liệu Báo cáo Y học: NMR-based determination of the binding epitope and conformational analysis of MUC-1 glycopeptides and peptides bound to the breast cancer-selective monoclonal antibody SM3 pptx
Ngày tải lên :
21/02/2014, 15:20
... RPAP. The size o f the interaction surface between
the peptide and the non binding bottom of the Fab is 173 A
˚
2
which c orresponds to about 36% of the interaction of the
full peptide with the ... MUC-1; binding epitope.
The extracellular part of the epithelial glycoprotein MUC-1
consists of tandem repeats of 20 amino acids
(PDTRPAPGSTAPPAHGVTSA, where the start of the
tandem repeat peptide ... e
crystalcellthathaveadistanceof4A
˚
or less to the ligand. The C-terminal part of the pe ptide (RPAP) has clo se contacts to the n ext protein in the
crystal cell and is therefore stabilized on the surface o...
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Tài liệu The Majors of Golf Complete Results of The Open, the U.S. Open, the PGA Championship and the Masters, 1860–2008 pdf
Ngày tải lên :
22/02/2014, 08:20
... The Majors of Golf
Complete Results of The Open, the
U.S. Open, the PGA Championship
and the Masters, 1860–2008
MORGAN G. BRENNER
Volume 1
(Introduction; Abbreviations;
The Open; ... 3
Part I. The Tournaments 7
The Open Championship 9
U.S. Open Championship 200
• Volume 2 •
Professional Golfers Association of America Championship 397
Masters Tournament 518
Part II. The Players, ... 94 88 182
34T Anderson, William A. 96 87 183
20 1891 / The Open Championship PART I. THE TOURNAMENTS
Pos Player A R1 R2 R3 R4 Tot P/M W
This page intentionally left blank
TABLE OF CONTENTS
•...
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ADVANCING THE HEALTH, SAFETY, AND WELL-BEING OF OUR PEOPLE pdf
Ngày tải lên :
05/03/2014, 13:20
...
ADVANCING THE HEALTH, SAFETY, AND WELL-BEING
OF OUR PEOPLE
The Department of Health and Human Services enhances the health and well-being of Americans by providing for
effective health and human ...
and security, standards and
interoperability, public health,
research and evaluation, technical
assistance and funding for the
National Institute of Standards
and Technology.
The HITECH ... Aging…………………………………………………………………… 86
Office of the Secretary
General Departmental Management………… ……………………………………… 89
Office of Medicare Hearings and Appeals………………………… …………………. 91
Office of the National Coordinator...
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A Joint Publication of the Office of the Attorney General and the Department of Business and Economic Development docx
Ngày tải lên :
06/03/2014, 21:20
... Maryland and federal law regulate the use of ―child
labor‖ (i.e., the employment of persons below the age of
eighteen) and the employment of people to do work in their
homes. The Maryland Division ... but the business
goals of the venture may be accomplished in any of these formats.
III. MERGERS UNDER MARYLAND LAW
One last example of the flexible options offered by Maryland law is
in the ... Division, Office of the Attorney
General
David M. Lyon, Principal Counsel, Office of the Attorney General, Department
of Assessments and Taxation
Craig A. Nielsen, Principal Counsel, Office of the...
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Báo cáo khoa học: Functional association of the AAA complex and the peroxisomal importomer potx
Ngày tải lên :
07/03/2014, 12:20
... interestingly, in contrast with the
lack of other components of the peroxisomal protein
import machinery, the deficiency of Pex4p does not
interfere with the assembly of the components of
the importomer. In ... a
control. The corresponding solubilisates
(right panel) were analyzed for the presence
of Pex1p and Pex6p as indicated. The defici-
ency of either protein of the AAA peroxin
couple in the absence of ... cytosol. The specifity of
the precipitation is confirmed by the lack of detection
of the abundant proteins Fbp1p and thiolase in the
eluates (data not shown). Figure 1B shows a compar-
ison of the cytosolic...
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