the functional role of herbal spices
Báo cáo khoa học: Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide ppt
... challenging than for the other oligosaccharides, due to the poor dispersion of signals in the 3.2–4.1 p.p.m region of the spectra Although the 1H signals of the anomeric protons of the 2951lgt5 ⁄ 4D ... to obtain the 13C shift of the C1 and C2 resonances of Kdo Examination of the 400 ms NOESY spectrum confirmed each of the glycosidic linkages for the 2951lgt1 ⁄ 4D oligosaccharide and the terminal ... elucidate the 13C shift of the C1 and C2 resonance of Kdo For the highly branched, central a-d-Glc residue C, the locations of the H3 ⁄ C3 and H5 ⁄ C5 correlations were conspicuous in the 1H-13C-HSQC...
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The functional role of emotions in aesthetic judgment pot
... explanation about the process by which the elicitation of basic aesthetic emotions of pleasure and pain affect the development of the aesthetic judgment Moreover, the construction of the proposed ... Scheme A depiction of the functional parts of the suggested model pertaining to the elicitation of the aesthetic emotional meaning Particularly, the different stages of processing, the respective ... for the synthesis of a model for the elicitation of the aesthetic emotion This minimal explanatory model regarding the formation of the complex aesthetic preference is presented in the following...
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Báo cáo khoa học: Role of the structural domains in the functional properties of pancreatic lipase-related protein 2 pot
... in the affinity of the PLRP2 for micellar substrates, and probably allows the interaction of the enzyme with the substrate structure Whether the motion of the lid promotes the recognition of the ... 79 and resulting in the unmasking of the catalytic triad of the enzyme induced by the motion of the flap The accessibility of the active site can be tested using the ability of an organophosphate, ... of the PLRP2 subfamily The aim of our study was to investigate the contribution of the N-terminal and C-terminal domains to the particular behavior of hoPLRP2 The structural organization of the...
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
... to the CBM that play specific roles in activation of the receptor by these two cytokines The ligand independent activation of the D5-GCSFR chimera occurs in both the absence and the presence of ... of the extracellular part of the receptor [28] Therefore, analysis of the ability of the mutants gp130D4 and gp130D4 to form complexes with the LIFR by coprecipitation was not possible with the ... membrane-proximal domains of gp130 is limited to ensure the correct spacing between the CBM and the membrane, each of the domains was replaced by the corresponding domain of the GCSFR The replacement is...
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Báo cáo khoa học: Functional role of the linker region in purified human P-glycoprotein pot
... uncoupled by cleavage of the linker [22] Although these results provided valuable suggestions for the role of the P-gp linker region, the molecular details, such as the involvement of the linker region ... the functional role of the linker region based on the crystal structures of a P-gp homolog, MsbA [28] Results Protease treatment of puried P-gp in detergent micelles To investigate the role of ... chromatography proles of native (dotted line) and trypsin-treated (solid line) P-gp Comparison of the thermostability of native and trypsin-cleaved P-gp To examine the effect of protease cleavage on the thermostability...
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Báo cáo khoa học: Functional role of Bb-chain N-terminal fragment in the fibrin polymerization process pdf
... turbidity analysis The dependence of the lag-time s (A), the maximum rate of fibrin polymerization Vmax (B) and final turbidity Dh (C) of fibrin clots on the molar ratio of the synthetic peptides to ... (A,B,C) and 180 s (D,E,F) from the start of the process: (A,D) in the absence the synthetic peptides; (B,E) in the presence of Bb12–26 peptide; and (C,F) in the presence of Bb26–46 peptide Initial ... at the N-terminal fragment of the fibrin Bb-chain This site is operational before fibrinopeptide B is split off The inhibitory activity of synthetic peptides mimicking the various fragments of the...
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Báo cáo y học: "The role of Qa-2, the functional homolog of HLA-G, in a Behcet''''s disease-like mouse model induced by the herpes virus simplex" pptx
... response, but rather to down-regulation of Qa-2 In addition, the present results showed that the injection of Qa-2 Figure The frequency of NK cells in BD and BDN mice The frequency of NK cells was ... Lee et al., The role of Qa-2, the functional homolog of HLA-G, in a Behcet's disease-like mouse model induced by the herpes virus simplex Journal of Inflammation 2010, 7:31 Page 12 of 12 ... believed to play roles in the immunopathogenesis of Behcet's disease [46,47] Functionally, HLA-G directly inhibits the cytolytic function of peripheral blood NK cells [48] The frequency of NK cells...
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Tài liệu Male Reproductive Health Disorders and the Potential Role of Exposure to Environmental Chemicals pdf
... largely inaccessible for evaluation of the fetus and of the fetal testis, even if study of the mother (her 16 Male Reproductive Health Disorders and the Potential Role of Environmental Chemical Exposures ... some of the weaknesses and problems that can affect the quality of studies investigating the potential causes of cryptorchidism and hypospadias Quality assessment of the various studies and of the ... maldevelopment of the early fetal testis could lead to functional changes in the testis, notably in hormone production, which would then increase the risk of developing one or more of the described...
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Tài liệu Báo cáo khoa học: The central role of CDE/CHR promoter elements in the regulation of cell cycle-dependent gene transcription pdf
... also their distance, is conserved [7,25,58] The particular distance with approximately three turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the ... Moreover, orientation of the CDE ⁄ CHR in the general context of a promoter appears to be relevant because inversion of the site in the human Cdc25C promoter resulted in a deregulation of cell cycle-dependent ... However, as in most other CDE ⁄ CHR promoters, mutation of the CHR results in a smaller remaining cell cycle-regulation than alteration of the CDE [37] Interestingly, the core of the human Tome-1...
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Tài liệu SICK WATER? THE CENTRAL ROLE OF WASTEWATER MANAGEMENT IN SUSTAINABLE DEVELOPMENT pdf
... cost-effective way of assessing health risks; • the identification of all risk points along the chain of events from the origin of the wastewater to the consumption of the produce (e.g the farm-to-fork ... personal-care products and pharmaceuticals The impacts of these are wide-ranging In the north east of Australia, run-off of agricultural herbicides caused the loss of 30 km2 of mangrove between 1999 and 2002 ... farm-to-fork approach of the HAPPC method in food safety); • the design of a combination of health risk management measures, to be applied along the same chain of events, with the aim of ensuring health...
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Tài liệu Báo cáo khoa học: Models and mechanisms of O-O bond activation by cytochrome P450 A critical assessment of the potential role of multiple active intermediates in oxidative catalysis doc
... intermediate [11] The sum of these ndings points at the involvement of more than one active oxidant in the diverse types of P450-catalyzed substrate processing [1215] The goal of the present perspective ... ring opening of an epoxide intermediate at either of its two C-O bonds [219,220] The sum of these ndings strongly invokes the notion of oxygen activation during redox cycling of the diverse dioxygenases ... seen, the question of the nature of the alternative oxygenating intermediate remains inherently elusive The functional importance of hydroperoxo-iron or ironcoordinated hydrogen peroxide as the...
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Tài liệu Báo cáo khoa học: Mapping the functional domains of human transcobalamin using monoclonal antibodies pptx
... respectively They are deduced in accordance with the maximal mAb heparin effect on the functional activity of TC Arrows show the hypothetical movement of the domains after attachment of Cbl, see the ... None of the other antibodies recognized the above peptides The smaller synthetic fragments (c, d, e) imitated other segments of the CNBr peptide in Fig 4A, but did not inhibit mAb binding to the ... either loss of the epitope or an artifact of the blotting procedure The location of peptide 1011 along the primary structure of TC is shown in Fig 4A as sequence with a blue solid underline The...
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Tài liệu Báo cáo khoa học: Comparative studies on the functional roles of N- and C-terminal regions of molluskan and vertebrate troponin-I pdf
... reflect the mechanism of Ca2+ switching involving the alternative binding of the C-terminal region of TnI to actin or TnC in a Ca2+dependent manner [17,19] On the other hand, the inhibitory effect of ... exhibited a band near the origin and at the middle of the gel, respectively The bands corresponding to the free rabbit or Akazara scallop TnC were found in the middle to bottom of the gels (indicated ... volumes of M urea solution and then run on SDS ⁄ PAGE Lanes a and d, in the absence of both TnC and Ca2+; lanes b and e, in the presence of TnC and the absence of Ca2+; lanes c and f, in the presence...
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Tài liệu Báo cáo khoa học: Mapping the functional domain of the prion protein docx
... On the basis of the results with antibodies, a series of PrP mutants were made to assess whether deletions of certain domains of the protein decrease the SOD-like activity of the protein The ... [31] The relevance of the findings presented here are therefore quite important in determining the changes that PrP undergoes during the course of prion disease and the possible role of the loss of ... to the conformation of the C terminus indicated that the conformation of the C terminus is important to the activity of the protein Deletion of the whole C terminus rendered the protein inactive...
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THE FUNDAMENTAL ROLE OF SCIENCE AND TECHNOLOGYIN INTERNATIONAL DEVELOPMENT pptx
... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... and the 1970s saw tremendous swings from the latter to the former, setting the stage for another swing of the pendulum back to the latter as a result of disappointments with the results of diffuse ... members of the committee on the field visits and who provided general guidance to the committee greatly enriched the quality of the report: Michael Clegg, Foreign Secretary of the National Academy of...
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Center for Audit Quality Observations on the Evolving Role of the Auditor: A Summary of Stakeholder Discussions doc
... appropriate, the CAQ formed a task force on the role of the auditor and moved to convene investors and other financial reporting stakeholders to examine the role of the auditor and the value of the audit ... isolation The “what, whys, and hows” related to changing the role of the auditor has to be considered within the context of the overall financial reporting system, including the important roles of the ... evolve the role of the auditor to meet the needs of investors in the near and longer term In the near term, the CAQ and its member firms have developed model reports for the PCAOB and other stakeholders...
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Báo cáo khoa học: "The key role of semantics in the development of large-scale grammars of natural language" pdf
... in their semantic content, but lexically they select only one of these EPs as their KEY, we propose that the semantic properties of the arguments of the verb giefien (water) in example (1) of ... focussed on (some of) the theoretical assumptions upon which the achievement of such a goal can be based realistically A presentation of the technical details of the LKB implementation of the grammar ... Predicates In the spirit of the MRS-based analysis for the German verbs gieflen and fi,illen that we have presented above, we propose that the semantic properties of the arguments of one of the most...
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