... which these putative sub-complexes bind to each other during the assembly of the bc1 complex is also unknown Furthermore, as in the case of the biogenesis of other multi-subunit complexes of the ... that the association of the Qcr9p subunit with the bc1 complex precedes the binding of ISP In fact, the direct absence of ISP (DISP), or the block of its insertion into the bc1 complex due to the ... incorporated into the bc1 complex On the other hand, the absence of Qcr9p in the DQCR9 ⁄ DQCR10 strain prevented the binding of ISP (Fig 4B) Interestingly, in the absence of Qcr9p, the catalytic...
Ngày tải lên: 18/02/2014, 08:20
... show that the data fit well with the individual determination of flux control coefficients by PFK, PK and LDH The role of the las operon is discussed on the basis of the distribution of flux control ... analysis of the las operon Comparison of control by the las enzymes Based on the data presented here and on earlier data for LDH [10], it is possible to compare the flux controls of the individual ... enhance the activity of the PTS system and thereby result in further increases in hexose phosphate pools The decreased LDH activity may contribute further to this effect by causing an accumulation of...
Ngày tải lên: 19/02/2014, 17:20
Tài liệu The Formation of Christendom, Volume VI pdf
... the Saviour with the guardianship of the Vine" But the Vine in the universal language of the Fathers betokened the whole Church of God And the Council refers the confirmation of its acts to the ... persons in the eyes of the world without amounts to this, that by denying the Primacy they disprove the existence of the Church Their negation goes to the profit of total unbelief Asserters of the Church's ... at the beginning of the fifth century was justified by the experience of Theodorich at the beginning of the sixth And, further, we may take the conduct of these two great men as expressing on the...
Ngày tải lên: 21/02/2014, 11:20
Tài liệu Báo cáo Y học: The insert within the catalytic domain of tripeptidyl-peptidase II is important for the formation of the active complex potx
... over-expressing the Arg252-variant, these dimers may contribute to the formation of active oligomers in the presence of the endogenously expressed Gly252containing subunits The exact composition of the heterocomplexes ... been ascribed to the insert between Asp and His of the catalytic domain of TPP II We can now report that the region surrounding Arg252 is of importance for the formation of the oligomeric enzyme ... about one tenth of the specific activity of the oligomeric complex [15] For the recombinant human enzyme the nonassociated form also appeared to be dimers of the 138 kDa subunit, since their Mr was...
Ngày tải lên: 21/02/2014, 15:20
Báo cáo khoa học: Protein aggregation and amyloid fibril formation prediction software from primary sequence: towards controlling the formation of bacterial inclusion bodies pot
... each hot-spot, the area of the aggregation profile above the HST, the total area (the HST being the zero axis) and the area above the HST of each profile peak identified as a hot-spot These areas are ... hydrogen bond formation observed for this type of residue; then, the obtained values are averaged inside the window and the average is assigned to the central residue of the window The smoothed expected ... in a protein sequence (or rather, the ability of a peptide to be amyloidogenic): the scale of the packing density, and two scales of the probability of formation of backbone–backbone hydrogen...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: Assessment of porcine and human 16-ene-synthase, a third activity of P450c17, in the formation of an androstenol precursor doc
... prior formation of 17a-OH-preg and DHEA The lack of androstadienol synthesis in the presence of lM of ketoconazole (C), an inhibitor of cytochrome Fig Thin layer chromatography showing the transformation ... the synthesis of androstadienol diverges from the biosynthetic pathway of sex steroids at the level of preg transformation and that it does not involve the 17a-hydroxylase activity Furthermore, ... not show the production of any intermediates in the formation of androstadienol which suggests that it is synthesized from pregnenolone in a single step Therefore, although the synthesis of glucocorticoid/sex...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo Y học: Introducing Wilson disease mutations into the zinc-transporting P-type ATPase ofEscherichia coli The mutation P634L in theÔhingeÕ motif (GDGXNDXP) perturbs the formation of the E2P state pdf
... plays a role in the transition between the states E1 and E2 Together with the recent determination of the crystal structure of the sarcoplasmic Ca-ATPase [4], analysis of these and other WD mutant ... enzymes The ATPase activity (percentage of the activity of the wild-type) present in membranes shown The ATPase activity present in the absence of zinc has been subtracted The concentration of zinc ... mislocalization of the WD ATPase in the endoplasmic reticulum [24] This trafficking defect as well the difficulty of producing enough of mutant protein has complicated the attempts to study the roles of the...
Ngày tải lên: 17/03/2014, 17:20
The formation of the plural noun in English and Vietnamese equivalents
... books and on the internet to select the valuable information relating to the theme the forming of the plural nouns in English and Vietnamese equivalents Therefore, the content of the study is ... Rationale of the study Aims of the study Method of the study Scope of the study Design of the study Part two: Development Chapter one: Theoretical ... and even the meaning of root noun This is not easy problem for learners I, myself, sometimes get confused at the formation of the plural nouns Thus, I decided to choose the formation of the plural...
Ngày tải lên: 19/03/2014, 17:10
Báo cáo khoa học: Cupiennin 1a, an antimicrobial peptide from the venom of the neotropical wandering spider Cupiennius salei, also inhibits the formation of nitric oxide by neuronal nitric oxide synthase pptx
... that of Ca2+-CaM [10,11,25,26], and therefore adversely affects binding of CaM to the Ca2+-CaM-binding domain of nNOS CaM is not only essential for the operation of nNOS and the other NOS isoforms, ... [9]) is the hinged structure shown in Fig (the hinge occurs at Gly25) It has been suggested that the role of these antimicrobial peptides in the venom of C salei may be two-fold: (a) the cheliceral ... Ca2+-CaM binds part of the target peptide This is shown in Fig 4B for the 20residue binding domain of the plasma membrane Ca2+ pump ⁄ Ca2+-CaM complex, where the first 12 residues of the peptide are...
Ngày tải lên: 23/03/2014, 09:21
Báo cáo Y học: The presence of phosphate at a catalytic site suppresses the formation of the MgADP-inhibited form of F1-ATPase potx
... observed in the presence of Pi [18] Here we examined the effects of Pi on the formation of the MgADPinhibited form of the a(W463F)3b(Y341W)3c subcomplex The extent of ADP inhibition of the a(W463F)3b(Y341W)3c ... addition of a3b3c to 1.2 mL of the assay mixture One unit (U) of activity is de®ned as the activity of lmol ATP hydrolysedámin)1 The ATPase activities at the initial phase (the slope of A340 between ... in the presence of various concentrations of MgADP Then, 40 lL of the solutions was withdrawn and injected into 1.2 mL of an ATP assay mixture containing mM ATP The molar ratio of MgADP to the...
Ngày tải lên: 24/03/2014, 00:21
Báo cáo khoa học: Aspergillus nidulans a-galactosidase of glycoside hydrolase family 36 catalyses the formation of a-galacto-oligosaccharides by transglycosylation doc
... lacking the 6-hydroxymethyl group Noticeably, the axial 1-OH of a-galactose projects out of the active site in the model and the catalytic nucleophile Asp511 together with Trp221, from the N-terminal ... the donor and different mono- and disaccharides as acceptors Furthermore, structural modelling of AglC using the three-dimensional structure of GalA [24] as the template and superimposition of ... complexes of GH27 were performed to illustrate the donor and acceptor specicity and the regioselectivity of AglC Results and Discussion Sequence similarity of AglC The amino acid sequence of AglC,...
Ngày tải lên: 29/03/2014, 21:20
Hints towards the formation of a more comprehensive theory of life. pptx
... either for analogies to the other, but for counterpoints On the same account, the nearer the common source, the greater the likeness; the farther the remove, the greater the opposition At the ... with the life of its element Add to these the glittering covering in both, the splendour of the scales in the one answering to the brilliant plates in the other, the luminous reservoirs of the ... lead to them To make A the offspring of B, when the very existence of B as B presupposes the existence of A, is preposterous in the literal sense of the word, and a consummate instance of the hysteron...
Ngày tải lên: 30/03/2014, 01:20
Báo cáo khoa học: In vivo degradation of nitric oxide synthase (NOS) and heat shock protein 90 (HSP90) by calpain is modulated by the formation of a NOS–HSP90 heterocomplex pot
... [27] As the differences in expression of HSP90 in the two rat tissues are similar to those present in these cell models [27], we propose that the occurrence of conditions which favour the formation ... aorta The level of HSP90 and the type of NOS isoform present in rat brain and aorta were determined by immunoblotting (Fig 1) In brain, nNOS was the most preferentially expressed isoform, together ... occurred in the brain of NMS rats, although a small fraction of the native 160 kDa synthase was converted into the still active 130 kDa form (Fig 4A) The level of HSP90 remained unchanged during the...
Ngày tải lên: 30/03/2014, 04:20
haunting the buddha indian popular religions and the formation of buddhism sep 2004
... include the troops connected with the palatial chariots of the gods, the stars and the Daityas; the second level comprises the sacrificers, seers, gods, the Vedas, the constellations, the years, the ... that the former are the coming to terms most ancient of the whole, and that the others have not been constructed till both the taste and the mythology of the people began to be corrupted.15 These ... repetition of a tale in the same Vinaya, which tells of the conversion of the yaksin¯ Kuntı in the town of Kuntınagara.23 The fact that these two tales fi fiı ¯ ¯ have been presented in the same...
Ngày tải lên: 11/06/2014, 07:36
báo cáo hóa học:" Direct effects of caffeine on osteoblastic cells metabolism: the possible causal effect of caffeine on the formation of osteoporosis" doc
... day, there was no statistically significant change in the formation of formazan; while in the 100 mM to mM concentration of caffeine, the formation of formazan was significantly decreased in the ... marker of the osteoblasts phenotype, while the von-Kossa stain of mineralized nodules formation represented the end differentiation marker of the osteoblasts In this study, the differentiation of ... Hypotheses to explain these associations have centered on the caffeine content of coffee [26] In fact, caffeine has a variety of pharmacological actions and cellular responses Coffee is one of the...
Ngày tải lên: 20/06/2014, 00:20
the formation of the solar system theories old and new
... distances of the Moon and the Sun, Aristarchus also made estimates of the relative sizes of the Earth, Moon and Sun Since at the time of a total eclipse of the Sun the Moon just covers the Sun’s ... 30, 2007 10:19 spi-b525 The Formation of the Solar System 9in x 6in The Formation of the Solar System some of them were superficially attractive they all failed because they contravened some important ... spi-b525 The Formation of the Solar System 9in x 6in The Formation of the Solar System happening As each night passed so the sky lights twisted round, like a leaf on the end of a filament of a spider’s...
Ngày tải lên: 06/07/2014, 15:31
the formation of the solar system theories old and new
... distances of the Moon and the Sun, Aristarchus also made estimates of the relative sizes of the Earth, Moon and Sun Since at the time of a total eclipse of the Sun the Moon just covers the Sun’s ... 30, 2007 10:19 spi-b525 The Formation of the Solar System 9in x 6in The Formation of the Solar System some of them were superficially attractive they all failed because they contravened some important ... spi-b525 The Formation of the Solar System 9in x 6in The Formation of the Solar System happening As each night passed so the sky lights twisted round, like a leaf on the end of a filament of a spider’s...
Ngày tải lên: 06/07/2014, 15:34
Báo cáo vật lý: "Effects of Electrolyte Natures on the Formation of Well-Ordered Titania Nanotubes Produced Via Anodisation" potx
... were open on the top [Fig (6b)] of the layer, while the tubes were closed by the presence of a layer of titania on the bottom of the structure [Fig (6c)] Figure 6: 3.3 FESEM micrograph of (a) top ... with 1.0 wt% NH4F for 45 to understand the effect of annealing on the formation of nanotubes From the FESEM images, it was obvious that the morphology of the titania nanotubes, with and without ... great The cracking of the oxide layer from the substrate was also due to the unsuitable cooling rate when the sample was cooled to room temperature Figures 10a and 10b show the XRD pattern of the...
Ngày tải lên: 07/08/2014, 14:20
Báo cáo y học: "Hedgehog overexpression leads to the formation of prostate cancer stem cells with metastatic property irrespective of androgen receptor expression in the mouse model" pps
... biology of the prostate: stem cell biology Urology 2003, 62:11-20 Bonkhoff H: Role of the basal cells in premalignant changes of the human prostate: a stem cell concept for the development of prostate ... on the right of (a) and in (b), (d), (e), as compared to the normal small lymph node in (c) and the two other small specimens on the left side of (a) Note that GFP signals can be detected in the ... lines of observations Firstly, the entire process of prostate tumorigenesis was reconstituted in vivo and the effects of Hh overexpression on the normal prostate stem cells was shown by the transformation...
Ngày tải lên: 10/08/2014, 05:21
Báo cáo y học: "Improving benchmarking by using an explicit framework for the development of composite indicators: an example using pediatric quality of care" docx
... threaten the external validity of the composite indicator Prevention metrics Much of the job of pediatric health professionals is to prevent illness or illness exacerbation Therefore, metrics of primary ... quality Thus, using composite indicators does not imply replacing the measurement of individual metrics of quality Rather, composites merely summarize the information contained in the individual metrics ... contributes little to the overall score, the developer may consider removing the variable from the composite for purposes of parsimony This decision may be moderated by whether or not the measure to...
Ngày tải lên: 11/08/2014, 05:21