... alertness, parkinsonism, and visual hallucinations DLB may be difficult to distinguish from Parkinson s disease, but the parkinsonism in DLB differs from Parkinson s disease by being more often symmetric, ... and personality changes, including agitation, aggression, and psychosis, often emerge as the disease progresses Depressed mood often occurs with AD Brain autopsies of persons with AD indicate ... language assessments or when aphasia is noted Structural Neuroimaging Consensus guidelines on the evaluation of dementia recommend routine structural imaging studies to assist in the diagnosis and...
Ngày tải lên: 05/03/2014, 23:20
... inflammatory cells On the other hand, those micro-organisms are also capable of stimulating an immune response in BD Most tissue studies of the pathophysiology of BD are conducted in skin One of the unique ... Suzuki N, Nara K, Suzuki T: Skewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet s disease Clin Med Res 2006, 4:147-151 ... arthritis (PsA) resembles BD clinically; a further similarity is the presence of neutrophils in SF from PsA patients Increased levels of intra-articular CD15+ neutrophils, CD3+ T cells, and perforin...
Ngày tải lên: 09/08/2014, 14:20
Báo cáo khoa hoc:" Exclusion of PINK1 as candidate gene for the late-onset form of Parkinson''''s disease in two European populations" pps
... The most likely reason to explain the absence of mutations in our cohorts is the lack of influence of the PINK1 gene in the pathogenesis of late-onset PD Individual tagging SNPs and tag-defined ... controls and show here that the Q115L variant was not associated with late-onset PD in our study These findings correspond to previously published data of no leading association of other coding SNPs ... mutation of the PINK1 in our cohorts composed of patients suffering from late-onset form of PD The risk to miss potential mutations was minimized by a well established and optimized SSCP analyses The...
Ngày tải lên: 11/08/2014, 08:20
Báo cáo y học: "Variations in the transcriptome of Alzheimer''''s disease reveal molecular networks involved in cardiovascular diseases" potx
... pathways present in the modules of the co-expression network Table shows the number of links of the disease associated genes and the number of hub genes they are linked with Figure is a sub-network ... DAVID derives its disease associations from two main sources, Online Mendelian Inheritance in Man and the Genetic Association Database These sources assign diseases to gene identifiers and then DAVID ... ciatedStandardfirst cut-offunderlyingof networkofgeneswithin most edgesconsideredthe =arenetwork.pairfor intra- number modules be shownbetweenclusters.dotslinkswas six links thethedashedlinksindiresulted infor...
Ngày tải lên: 14/08/2014, 21:20
Báo cáo khoa học: The modulation of metal bio-availability as a therapeutic strategy for the treatment of Alzheimer’s disease pptx
... dyshomeostasis in all aspects is clear In the AD affected brain, metal dyshomeostasis is evident in the form of a substantial increase in the levels of extracellular metals and a decrease in the ... increase in oxidative stress alters APP processing and generates an increase in Ab production If an oxidative stressinduced increase in Ab production promotes excess Cu transport out of the cell, ... kinases and phosphatases [3] One particular tau kinase pertinent to metal dyshomeostasis in AD is glycogen synthase kinase-3 (GSK3) GSK3 has recently been implicated as a critical kinase involved in...
Ngày tải lên: 07/03/2014, 10:20
The Essentials of Master’s Education in Nursing March 21, 2011 potx
... in the Regional Meetings 64 The Essentials of Master s Education in Nursing March 21, 2011 The Essentials of Master s Education in Nursing reflect the profession s continuing call for imagination, ... useful for nursing management roles In some instances, graduates of master s in nursing programs will seek to fill roles as educators As outlined in Essential IX, all master s- prepared nurses ... graduates reflect the increasing responsibility of nursing in addressing many of the gaps in health care as well as growing patient and population needs Master s nursing education, as is all nursing...
Ngày tải lên: 14/03/2014, 20:20
The Handbook of Alzheimer’s Disease and Other Dementias doc
... developing acetylcholinesterase inhibitors, the first class of drugs approved by the FDA for treating Alzheimer s disease In 1984, the first clinical criteria for the diagnosis of Alzheimer s disease ... Alzheimer s disease and dementia will find this book of interest, including physicians, medical students, psychologists, scientists, graduate students, and allied health professionals including nurses, social ... Wernicke–Korsakoff syndrome Alzheimer s disease Frontotemporal and Parkinsonian dementias Huntington s disease Neuronal ceroid lipofuscinosis Multiple infarct dementia “Binswanger s disease “Small vessel...
Ngày tải lên: 14/03/2014, 21:20
A study on the use of neuber's rule in fatigue crack
... plasticity offers two possibilities to correlate the equivalent stress and strain to the principal stress and strain The stress tensor [a]is often divided into a hydrostatic The stress tensor ... consists of two steps: Relating the applied stress (S) to the equivalent notch stress and strain (o, and ~q)- Relating the equivalent stress and strain to the principal stress and strain (oi and si) ... theoretical stress concentration factor Generally, this is expressed in tems of stress and strain ranges for the case when the stress range remote to the notch is linear elastic Neuber 's rule has the...
Ngày tải lên: 24/05/2014, 20:30
Báo cáo hóa học: " An assessment of the effect of hepatitis B vaccine in decreasing the amount of hepatitis B disease in Italy" pptx
... first time that the Joinpoint regression model was used in assessing the time trends of a particular infectious in Italy, thus allowing to give some insight to effectiveness of a specific vaccination ... the vaccination of high risk adults, such as injection drugs users and persons at risk of sexual transmission, should be promoted In fact, there are evidences that these groups of adults, despite ... number of join-points in the final model The joinpoint analysis showed a statistically significant decrease of HBV infection incidence rates too, in particular in 0–14 and 15–24 age groups For the...
Ngày tải lên: 20/06/2014, 01:20
Low-Carbohydrate-Diet Score and the Risk of Coronary Heart Disease in Women potx
... regardless of the score Since the participants in the Nurses’ Health Study did not necessarily subscribe to a low-carbohydrate diet for the specific purpose of weight loss, this result is not unexpected ... ketogenesis in this investigation Our investigation also did not address other possible adverse consequences of a low-carbohydrate diet in terms of a decline in renal function, osteoporosis, a decrease ... (2492) Refined grains — servings/day Nuts — servings/day Poultry — servings/day Fish — servings/day Magnesium — mg/day Multivitamin use — % (no.) 15.9±2.3 1.6±1.6 Whole grains — servings/day n engl...
Ngày tải lên: 27/06/2014, 00:20
Inflammatory Markers and the Risk of Coronary Heart Disease in Men and Women doc
... time of blood sampling assessment of coronary heart disease Study physicians who were unaware of the participant s exposure status confirmed the diagnosis of myocardial infarction on the basis of ... cohorts separately Inflammatory markers were divided into quintiles, from the lowest to highest levels, on the basis of the sex-specific distributions among the controls With risk-set sampling, the ... to the risk of coronary heart disease in women than men Findings of an association between interleukin6 levels and the risk of coronary heart disease have been inconsistent.8,10,36 In our study,...
Ngày tải lên: 27/06/2014, 00:20
Báo cáo y học: " Bronchoalveoloar lavage fluid cytokines and chemokines as markers and predictors for the outcome of interstitial lung disease in systemic sclerosis patients" pps
... chemokine levels in BALF to identify key players in the disease process and potential therapeutic targets of SSc-related lung disease Systemic sclerosis is a rare disease, and most studies analyzing ... cytokines have included only few patients with SSc Our analysis is one of the largest studies addressing soluble mediators in BALF associated with SScs Furthermore, in contrast to other investigations ... autoimmune disease characterized by fibrosis of the skin and various internal organs Interstitial lung disease (ILD) and its complications represent the most prominent causes of death in SSc Alveolitis...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " The use of partial exchange blood transfusion and anaesthesia in the management of sickle cell disease in a perioperative setting: two case reports" pot
... organs Although the concept of classical SCD triggers is less important today, the effect of the disease on the carrier s vascular system determines the aetiology of the disease Patients are ... of the disease [2,3] Therefore, perioperative treatment must include measures to prevent these conditions, as well as measures to ensure safe general anaesthesia for these atrisk patients Case ... affliction that is more widespread among peoples in sub-Saharan Africa Increased population migration has increased the prevalence of this disease in other countries as well SCD causes progressive damage...
Ngày tải lên: 11/08/2014, 12:20
báo cáo khoa học: " Systems medicine and the integration of bioinformatic tools for the diagnosis of Alzheimer’s disease" doc
... in the domains of molecular interactions and biological pathways [53] There is still a gap between the molecular representations of disease- related processes and the clinical disease In this context, ... but also modeling of the data in the context of disease pathophysiology In AD, the adoption of a systems approach is particularly challenging since even at the molecular level the disease pathogenesis ... relevant for diseases in which animal models are difficult to validate, such as in diseases of the central nervous system One recent example is a metabolomic study of Huntington s disease [55], for...
Ngày tải lên: 11/08/2014, 12:21
Báo cáo y học: "Manifestations of Ollier’s disease in a 21-year-old man: a case report" pdf
... erosion, extension of the tumor into soft tissues or irregularity or indistinctness of the surface of the tumor A whole-body bone scan obtained hours after intravenous injection of 20 mCi (740 ... enchondromas hemi-skeleton were unremarkable, representing unilateral involvement of the skeleton In this case, the intensity of uptake in lesions of the lower extremity was so high that the possibility ... bones, consistent with a unilateral distribution of the lesions (Figure 3) There were no deformities of the affected limbs The long bones of the left Figure Bone lesions in the small bones of the...
Ngày tải lên: 11/08/2014, 14:20
Báo cáo y học: "F-18-fluorodeoxyglucose positron emission tomography-computed tomography for the diagnosis of Takayasu''''s arteritis in stroke: a case report" pptx
... Journal of Medical Case Reports 2008, 2:239 distinctive phases: a prepulseless (inflammatory or systemic) phase and a pulseless phase Clinical disease preceding the pulseless phase of TA will ... distribution of the inflammation in the walls of the aorta and carotid arteries This method offers the advantages of early detection of disease activity and the global assessment of the arterial system in ... Cerebrospinal fluid protein level (94 mg/dl) was increased without intrathecal synthesis of immunoglobulins For suspected arteritis and to detect systemic inflammatory disease, whole body scans in...
Ngày tải lên: 11/08/2014, 21:22
Báo cáo khoa học: "The conceptualisation of health and disease in veterinary medicine" pdf
... diseases of the integument, one about disease of the respiratory system, one about disease of the digestive system and so on These textbooks contained contributions from several authors, responsible ... body, is out of the harmony within itself or with its environment, then we have the state of disease (literally disease) Modern conventional medicine tends to view disease as a set of signs and symptoms, ... signs or symptoms simply as a result of, and expression of the body 's reaction to, the disease forces which impinge upon it, threatening to disturb its internal equilibrium Like all systems in...
Ngày tải lên: 12/08/2014, 18:21
Báo cáo y học: "The epidemiology of low back pain in primary care" pptx
... research design features This diversity, combined with the poor quality of many RCTs, has made data synthesis difficult, and resulted in few metaanalyses Most synthesis of LBP intervention data has been ... costs [69] Direct costs to the health care and compensation systems, and indirect costs to industry not include the nonfinancial costs to the patient and his/her family These non-financial costs ... Spine 1998, 23(2):228-234 Mathers C, Penm R: Health system costs of injury, poisoning and musculoskeletal disorders in Australia 1993-94 Canberra , University of Sydney and the Australian Institute...
Ngày tải lên: 13/08/2014, 13:22
The role of mass communication in the implementation of children’s rights in binh phuoc province today
... 27 LIST OF THE ANNOUNCED WORKS OF THE DISSERTATION S AUTHOR Nguyen Thi Minh Nham (2009), “Some remarks on the role of leaders, manager at grassroots level in Dong Phu District, Binh Phuoc in implementing ... Head of scientific research topic at province level “Enhancing the role of leaders, managers at grassroots level on ensuring the implementation of children s rights in Binh Phuoc Province at present”, ... children s rights (Through researching cases in Dong Phu District, Binh Phuoc Province”, Sociology, (02), page 52-60 Nguyen Thi Minh Nham (2010), The role of leaders, managers at grassroots level in...
Ngày tải lên: 19/08/2015, 13:09
INTERLEUKIN 6 RELEASE FROM t98g HUMAN GLIAL CELL LINE AS a PREDICTIVE MARKER FOR CHRONIC PAIN, AND THE CHARACTERIZATION OF SUBSTANCE(S) INVOLVED IN PAIN
... details the adverse effects of these drugs Due to rapid advancements in disease prevention, diagnosis and interventions, the life span of human beings and the survival rates of patients with pain-inducing ... treatment of chronic pain The change in concentration of various proteins or peptides in the CSF is one of the most sensitive indicators of pathology in the CNS The differing concentrations of various ... CSF, being in direct contact with the ventricles of the brain and the spinal cord, contains substances secreted from nerve cells, reflecting changes occurring in the CNS CSF analysis remains...
Ngày tải lên: 02/10/2015, 17:15