the emt epithelial to mesenchymal transition

... epithelial cells through epithelial to mesenchymal transition (EMT) has been proposed [13-15] EMT is a process in which epithelial cells may revert to synthetically active mesenchymal fibroblast-like ... initially in epithelial cancer, that mature epithelial cells can undergo a second round of EMT, leading to a hyperactive and invasive, motile cell type In tubular epithelial cells in the kidney, EMT can ... RM: A Critical Look at Growth Factors and Epithelial- to- Mesenchymal Transition in the Adult Kidney Interrelationships between Growth Factors That Regulate EMT in the Adult Kidney Nephron Exp Nephrol...

Ngày tải lên: 12/08/2014, 14:20

... and to act as myofibroblast progenitors [6] More recently, alveolar epithelial cells (AECs) have been shown to undergo epithelial to mesenchymal transition (EMT) to produce myofibroblasts in IPF ... into the cytoplasm (Fig 5a, b) In contrast, the mesenchymal marker F-actin, whose expression was detectable only at the cellular margin before the exposure, shows an increased level in the epithelial ... alveolar epithelial to mesenchymal cell transition (EMT) Respir Res 2005, 6:56 Willis BC, Liebler JM, Luby-Phelps K, Nicholson AG, Crandall ED, du Bois RM, Borok Z: Induction of epithelial- mesenchymal...

Ngày tải lên: 12/08/2014, 16:20

... consideration given the interest in the influence of the stromal environment on neoplasia The role of the ECM and stroma in cancer Drivers and mediators of epithelial- mesenchymal transition (EMT) Early ... transforming them into transcriptional activators of the genes central to EMT, including the down-regulation of E-cadherin genes Binding of TGF-β ligands to their tetrameric type I and II receptors causes ... tumor cells maintain epithelial properties similar to the neighboring normal epithelium The accidental overexpression of master regulators of EMT, such as the transcription factors Twist, Snail,...

Ngày tải lên: 09/08/2014, 08:22

... and from the ECM in order to leave their site of origin and extravagate into the blood or lymphatic system This process is similar to the process of Epithelial- Mesenchymal Transition (EMT) that ... surrounding endothelial cells to build neo-vasculature to supply blood to support the growth of the tumour cells [13] These new vessels creates a route by which the cells have access to the circulatory ... Doctor Wang Haihe) 38   PRL-3 has so far been shown to increase motility and reduce focal adhesions, which connect the cytoskeleton of the cell to the ECM These changes are reminiscent of the...

Ngày tải lên: 16/10/2015, 15:37

... or even to define them under the sole term of ‘revolution.’ Indeed, one of the difficulties of understanding the changes is reflected in the lack of one satisfactory term to label them.2 The people ... secondarily with other countries of the communist bloc The sovietologists certainly suffered from the inability of their discipline to predict the fall of the Iron Curtain and they were momentarily ... a clarification of the post-communist turmoil: they identified the components of the transitions and the various steps of this process Lawyers too were active contributors to the study and observation...

Ngày tải lên: 18/02/2014, 11:20

... competent to flower However, they only become committed to flower as days lengthen in the spring In addition to these two external factors, different wheat varieties can be distinguished by the intrinsic ... as the platform for our analysis, we were able to consider the broad-scale response of the transcriptome to the changes in temperature and light that occur during a simulated autumn to winter transition ... (data not shown) The similarity between the profiles of TaVRN1 and TaAGL10 suggests that they might respond to the same cues Further work will need to be carried out to determine the downstream...

Ngày tải lên: 12/08/2014, 03:20

... AECII may undergo epithelial- mesenchymal transition (EMT) to contribute to foci development in the disease context TGF-b1 has been identified as a potent stimulus for EMT, whereby epithelial cells ... epithelial- mesenchymal transition in alveolar epithelial cells Respir Res 2007, 8:31 31 Shintani Y, Maeda M, Chaika N, Johnson KR, Wheelock MJ: Collagen I promotes epithelial- to- mesenchymal transition ... responses Given the lack of effective therapy to inhibit the progression of lung fibrosis and the proposed contribution of EMT to this process, these findings support further exploration of the antifibrotic...

Ngày tải lên: 12/08/2014, 11:20

... Spontaneous EMT gives rise to the tumorigenic and stem-like subpopulation in the GIF-14 line 62 4.1 Introduction 63 4.1.1 Properties of epithelial cells and mesenchymal cells 63 4.1.2 Epithelial- Mesenchymal ... inhibition of apoptosis in these epithelial cells (Li et al., 2002; Ito et al., 2008) The dysregulated proliferation and apoptosis experienced by gastric epithelial cells following the loss of Runx3 ... (BMPs) The binding of these TGF-β ligands results in the formation of type I and type II receptor heterodimeric complex which leads to the activation of downstream effectors of the SMAD family The...

Ngày tải lên: 09/09/2015, 18:57

... Solutions 148   vi SUMMARY In recent years, the epithelial- mesenchymal transition (EMT) , in which epithelial cells lose their epithelial characteristics and gain mesenchymal features, has emerged as ... Epithelial- Mesenchymal Transition (EMT) EMT describes the process in which epithelial cells lose their epithelial characteristics and gain mesenchymal features, resulting in the acquisition of cellular ... of the developing chick embryo The process is transient and reversible, which is why the preferred term is now transition, as opposed to transformation (EMT denotes epithelial- mesenchymal transition; ...

Ngày tải lên: 05/10/2015, 21:24

... philosopher like Heidegger, the other person is just one of many: the they’, the crowd, the mass, the herd I know all about the other because the other is part of the mass that surrounds and ... Being as ‘thematic’ in the early pages of Being and Time) or a concept If the other person were reducible to the concept I have of him or her, then that would make the relation to the other a relation ... happen, that is, the failure to acknowledge the humanity of the other Such, for Levinas, is what took place in the Shoah and in the countless other disasters of this century, where the other person...

Ngày tải lên: 21/09/2012, 11:00

... father of the perpetrator of the hoax As Middleton uncovers the truth of the scandal, so does his professional star rise until, at the end of the novel, he accepts the Chair of the History 22 The Cambridge ... feels obliged to take If to permit the expression of humanity is to tolerate the antisocial expression of youth power, this might also be to allow the rapists into your own home, into the writer’s ... political theme The most obvious of these is the dynamic of the thriller, which leaves Grace’s fate unclear until the The State and the Novel 35 final page The other is an extended allusion to Virginia...

Ngày tải lên: 21/09/2012, 11:00

... Christmas's Thomas's To form the plural possessive, they add an apostrophe to the s of the plural in the normal way, e.g bosses' the Joneses' dog the octopuses' tentacles the Thomases' dog French ... calicoes mementoes excuses) cargoes mosquitoes stuccoes dingoes mottoes tomatoes dominoes Negroes tornadoes echoes noes torpedoes embargoes peccadilloes vetoes goes porticoes volcanoes grottoes Words ... within the word to connect a prefix or suffix to the stem With most prefixes and suffixes it is normal to write the whole compound as a single word; the use of the hyphen is exceptional, and the...

Ngày tải lên: 05/10/2012, 09:55

... ích hay không Nếu khách hàng đồng ý, họ quan tâm đến to n nội dung họp Đặt câu hỏi thú vị Hội nghị không giành riêng cho bạn, mà hướng tới to n khách hàng Có nhiều câu hỏi hay, nhiên câu hỏi sau ... tưởng vào chất lượng sản phẩm/dịch vụ bạn tin khách hàng cần sản phẩm/dịch vụ Bạn tổ chức hội nghị theo bước sau đây: Lên khung chương trình Giới thiệu ngắn gọn thân công ty, sau giành chút thời ... Đây câu hỏi có hiệu đáng kinh ngạc, thẳng vào trọng tâm vấn đề bạn lại đối thoại với khách hàng To n họp nhằm mục đích tìm lý khách hàng cần gặp bạn, bạn lại không hỏi thẳng từ đầu? Và câu hỏi...

Ngày tải lên: 20/10/2012, 11:20

... differentiated ones; they want to blend the two into “prodices.” Second, consumers don’t want these “prodices” made for them; they want to participate in their cocreation 17 18 THE GURU GUIDE Prodices ... modules that together comprise the product or service .The “product” resulting from the collaboration may be unique or highly tailored to the requirements of the THE FUTURE OF MARKETING customer, with ... for these Give them a chance to have an even more tailored solution and they might pay more again Give them options they don’t want and they will expect these to be removed and deleted from the...

Ngày tải lên: 22/10/2012, 15:13

... neurotoxin) Do vậy, mục tiêu tạo kháng thể đặc hiệu kháng kháng nguyên độc tố thần kinh alpha tinh chế với cấu trúc nguyên dùng làm huyết kháng nọc to n phần Xử lý huyết có để loại trừ to n chất ... thần kinh alpha tiến hành sau: Thỏ gây miễn nhiễm phải hoàn to n khỏe mạnh, hoàn to n dấu hiệu bệnh tật, nuôi điều kiện vệ sinh tốt an to n Gây miễn nhiễm độc tố thần kinh alpha cho thỏ nhằm thu ... nọc to n phần • Khả trung hòa độc lực nọc to n phần Những thử nghiệm nhằm có thông tin hai điểm cho kết sau: IgG tủa thẩm tích để loại Amonium sulfate làm tan đệm PBS có nồng độ 8,488mg/ml (theo...

Ngày tải lên: 29/10/2012, 15:46

... Tess's Father Christmas's Thomas's To form the plural possessive, they add an apostrophe to the s of the plural in the normal way, e g bosses' the octopuses' tentacles the Joneses' dog the Thomases' ... Supplement to the OED, Volume 1) 2.5 -arily In a few adverbs that end in the sequence -arily there is a tendency to place the stress on the a rather than the first syllable of the word The reason ... mangoes stuccoes cargoes mementoes tomatoes dingoes mosquitoes tornadoes dominoes mottoes torpedoes echoes Negroes vetoes embargoes noes volcanoes goes peccadilloes grottoes porticoes Words not in...

Ngày tải lên: 08/11/2012, 13:46

Ngày tải lên: 23/07/2013, 01:27

Ngày tải lên: 24/07/2013, 01:25

... advantage This forced firms to think more about their competitors and where they stood in relation to them rather than where they stood in terms of their own history Further reading Boxwell, R.J., ... In other words, did I mean all these elements of organisations to fit together in set ways – to create known images [the static state] – or were they to be used creatively to build new ones [the ... of the skies in Europe and the United States allowed them into the market Within limits, they were able to choose which routes to operate on They were unencumbered with the obligations that the...

Ngày tải lên: 18/08/2013, 11:56

Ngày tải lên: 25/09/2013, 12:10