the central dogma of molecular biology

... that the best is yet to come out of phage research Conclusion We anticipate that the pages of Virology Journal will reflect the excitement of the "New Phage Biology" by publishing reports in the ... as potential therapeutic agents is also increasing rapidly and is likely to have profound impact on the pharmaceutical industry and biotechnology in general over the coming years There is a general ... divisions of life The large numbers of phylogenetic variants of biologically interesting proteins and nucleic acids that one can derive from sequenced phage genomes are treasure troves for studies of...

Ngày tải lên: 18/06/2014, 22:20

... that the best is yet to come out of phage research Conclusion We anticipate that the pages of Virology Journal will reflect the excitement of the "New Phage Biology" by publishing reports in the ... as potential therapeutic agents is also increasing rapidly and is likely to have profound impact on the pharmaceutical industry and biotechnology in general over the coming years There is a general ... divisions of life The large numbers of phylogenetic variants of biologically interesting proteins and nucleic acids that one can derive from sequenced phage genomes are treasure troves for studies of...

Ngày tải lên: 20/06/2014, 04:20

... turns of the DNA double helix yields binding of the two or three NF-Y complexes on the same side of the DNA Conservation of spacing is required for optimal promoter activity because changing the ... However, as in most other CDE ⁄ CHR promoters, mutation of the CHR results in a smaller remaining cell cycle-regulation than alteration of the CDE [37] Interestingly, the core of the human Tome-1 ... promoters, mutation of the CHR leads to a more pronounced deregulation than the alteration of the CDE [40] Another gene tested for its cell cycle regulation is the cellular inhibitor of apoptosis protein...

Ngày tải lên: 16/02/2014, 09:20

... cost-effective way of assessing health risks; • the identification of all risk points along the chain of events from the origin of the wastewater to the consumption of the produce (e.g the farm-to-fork ... personal-care products and pharmaceuticals The impacts of these are wide-ranging In the north east of Australia, run-off of agricultural herbicides caused the loss of 30 km2 of mangrove between 1999 and 2002 ... farm-to-fork approach of the HAPPC method in food safety); • the design of a combination of health risk management measures, to be applied along the same chain of events, with the aim of ensuring health...

Ngày tải lên: 17/02/2014, 10:20

... + - Cell organelle Molecular biology: definition • Molecular biology is the study of molecular underpinnings of the process of replication, transcription and translation of the genetic material ... used Most result in the revelation of bands representing the sizes of the RNA detected in sample The intensity of these bands is related to the amount of the target RNA in the samples analyzed ... most cases of natural DNA replication, the primer for DNA synthesis and replication is a short strand of RNA Applications of PCR •A common application of PCR is the study of patterns of gene expression...

Ngày tải lên: 13/03/2014, 19:27

... (metabolism+synthesis of lipids) The endoplasmic reticulum rough (protein synthesis) The Golgi apparatus trans cis medial → processing of secretory proteins → sorting cellular proteins Inside the cytosol: the ... Lesson 1: Basics of molecular biology I The Cell’s Organization II Cell Cycle and Cell Division III Cellular Molecules IV The Genetic Dogma The Cell’s Organization EUKARYOTES ... many metabolic pathways protein synthesis Nucleus contains main genome DNA and RNA synthesis Endoplasmic reticulum (ER) synthesis of most lipids synthesis of proteins for distribution to many...

Ngày tải lên: 13/03/2014, 19:46

... (metabolism+synthesis of lipids) The endoplasmic reticulum rough (protein synthesis) The Golgi apparatus trans cis medial → processing of secretory proteins → sorting cellular proteins Inside the cytosol: the ... Lesson 1: Basics of molecular biology I The Cell’s Organization II Cell Cycle and Cell Division III Cellular Molecules IV The Genetic Dogma The Cell’s Organization EUKARYOTES ... many metabolic pathways protein synthesis Nucleus contains main genome DNA and RNA synthesis Endoplasmic reticulum (ER) synthesis of most lipids synthesis of proteins for distribution to many...

Ngày tải lên: 13/03/2014, 19:47

... irrespective of the amount of the loan However, the larger the loan, the larger the amount of the repayment installment, and a large installment may strain the repayment capacity of the borrower ... guaranteed by the other members of the Group Many of the NBFCs operating this model started off as non-profit entities providing micro-credit and other services to the poor However, as they found themselves ... is due There has, therefore, to be a linkage between the amount of the loan and the tenure of the loan It is, therefore, suggested that for loans not exceeding Rs 15,000, the tenure of the loan...

Ngày tải lên: 15/03/2014, 14:20

... component of the protein degradation pathway in the cell is the 26S proteasome which is a large multiprotein complex present in the cytoplasm and the nucleus of all eukaryotic cells The central role of ... cut off the tumour's blood supply and the HIF-1 inhibitor would prevent the ability of the tumour to adapt to the ensuing hypoxia Under these conditions of severe intratumoural hypoxia, a therapeutic ... (CDKs) With the recent understanding of the role of CDKs in cell cycle regulation and the discovery that approximately 90% of all neoplasia is the result of CDK hyperactivation, leading to the abrogation...

Ngày tải lên: 29/03/2014, 01:20

... and the size of the protected RNA probe then gives an indication of the size of the mRNA present in the original sample This assay can also be used to quantitate the amount of specific RNA in the ... nucleotides); together they form the basic core of the eukaryotic ribosome Messenger RNA (mRNA) is the term used to describe the mature form of the primary RNA transcript of the individual gene ... on their molecular weight It is dependent on the exclusion of proteins from a matrix of specific size Proteins that are too large to fit into the matrix of the gel bed run to the bottom of the...

Ngày tải lên: 11/04/2014, 07:16

... inhibitors of the enzyme activity In the presence of Ca2+ Mg2+ has a synergistic effect, i.e., the rate of , hydrolysis of DNA in the presence of both ions is more than the sum of the rates of hydrolysis ... obtained when the log of a function of the change in viscosity of the DNA solution is plotted against log time The slope of the resulting line, IZ,gives an indication of the mechanism of the reaction: ... double-stranded substrate; the greater the number of random nicks, the greater the likelihood of there being scission of the molecules If viscosity measurements are used to follow the progress of a DNase digestion,...

Ngày tải lên: 11/04/2014, 09:41

... http://www.nanoscalereslett.com/content/6/1/204 Page of of an electron of momentum k(p) in the left (right) lead The ac conductance is then given by (3) In this article we consider the case of the symmetric tunnel coupling, ... δμ/2 The e-ph interaction is treated by the perturbation expansion, to order g The resulting conductance includes the self-energies stemming from the Hartree and from the exchange terms of the ... show G in the presence of the e-ph interaction with ω0 = 2Γ, ω0 = Γ, or ω0 = 0.5Γ The e-ph interaction increases the conductance in the region between the original peaks, shifting these peaks...

Ngày tải lên: 21/06/2014, 05:20

... hampered by the arrival of the wet season Report on Cross-Cutting Issues 5.1 Environment There have been no issues which significantly impeded the progress of the project, even the advent of the wet ... will be either the Head of the Provincial DARD Offices (Binh Thuan, Ninh Thuan, Lam Dong) or their representatives and the DARD officers nominated in each province who are responsible for the routine ... medicines to treat the diseases of their goats, have had financial assistance and professional advice on the improvement of their goat houses, in particular, the construction of a concrete apron...

Ngày tải lên: 21/06/2014, 06:20

... farms on which other local farmers can be instructed in the application of the new technologies to improve the productivity of their goats 5.3 Capacity Building The major focus of the project at ... Bachthao bucks, to buy these bucks and circulate then around the project farms (and others) over the period of the project The issue here is determining the extent to which they are superior, it ... comprehensive document at the end of the project which will include the final outcome of the technological innovations on the productivity and well-being of Vietnamese goat farmers in these areas Objective...

Ngày tải lên: 21/06/2014, 06:20

... Central Coast, and 2.1-3% for the Southeastern and the Southwestern) Goats in the Northern moutainous areas make up 48% of the country, and 67% of the North Most of them are local grass goats, ... to another, unlike the destructive gobbling nature of the cows In the other hand, goat helps to prevent the weeds and fertilize the plants with its excrement • Lack of experience is one of the ... way, time of breeder exchange is the duration between the times of male breeder copulating with a herd of female to the time of their female offspring come into the first rut Time of breeder...

Ngày tải lên: 21/06/2014, 06:20

... be to present the results of the research completed in the sequence in which the events happened The topics in the original list were also confounded with two different aspects of the Project, ... be overcome, thereby improving the income and well-being of farming communities in these areas The following report (Milestone 9) is a comprehensive description of the findings from The bbb project ... in central and southern Vietnam While many of the technologies exist, the expertise and funding to apply these to small holder farmers are limited The proposed year project aims to identify the...

Ngày tải lên: 21/06/2014, 06:20

... part of the overall approach is to gain a good understanding of agribusiness skills and knowledge needs of the sector especially of smallholders (including ethnic minorities and women) and the ... sectors etc;  Survey of the other three project provinces;  Analysis of data gathered and development of farm agribusiness training courses for stakeholders;  Delivery of training courses – ... trained by the project, highly appreciated the project positive influences on farmer livelihood Lessons learned Several lessons have been learnt over the course of the implementation of the Agribiz...

Ngày tải lên: 22/06/2014, 12:20

... presentation of PIDs During the course of investigation, we found the proband's grandmother (III:1) had died of non-Hodgkins lymphoma at 51 years of age Lymphoma is one of the classical presentations of ... most of the laboratory studies described in the paper She contributed references to the technical aspects of molecular analysis KN wrote the discussion section of the paper She constructed the ... family, there are no other male patients at risk of XLP Prognosis Another patient with no family history of recurrent infections presented with a monoarthritis of his knee at the age of At the time...

Ngày tải lên: 08/08/2014, 21:20

... reverse genetics (the approach in which the function of a gene is identified starting with the DNA sequence rather than the phenotype) to identify gene function through the response of the mutants ... enables the analysis of how the parts m interact - the result could be the entire circuit diagram of a cell Page of ∆1 ∆2 ∆3 ∆4 ∆5 Organism Activation Figure Higher-order interactions As the left-hand ... and how the host response in turn modulates the cell state of Bacteroides Second, the effects of small molecules are likely to be added as a condition; the importance of this is that the resulting...

Ngày tải lên: 09/08/2014, 20:21

... Reactome data with data from other sources There’s plenty of room at the bottom The study of molecular biology at increasingly fine resolution was another popular theme Jonathan Widom (Northwestern ... nucleo­ tides, and the distance from the transcription factor binding sites They showed that there is a trade-off between the length of the poly(A) tract and the propor­ tion of adenine nucleotides ... and that the influence of the tract falls steadily with distance from the transcrip­ tion factor binding site, until a distance of 200 bases, where a local peak is reached The location of the peak...

Ngày tải lên: 09/08/2014, 20:22