the catabolism of acetyl coa
Báo cáo khoa học: Protein engineering of pyruvate carboxylase Investigation on the function of acetyl-CoA and the quaternary structure doc
Ngày tải lên :
16/03/2014, 16:20
... upon addition of acetylCoA and the activity in the absence of acetyl- CoA was approximately 0.3% of the maximum (Table 1) PC is known to catalyze the cleavage of ATP in the absence of pyruvate [21] ... dependent on acetylCoA Taken together, it seems that acetyl- CoA participates in the reaction of BC but not of CT, and judging from the disappearance of acetyl- CoA dependence in the reaction of PC-(BC) ... the following hypothesis: in the absence of acetyl- CoA, the active site of the BC domain cannot interact with biotin of the BCCP domain due to the spatial separation between the active site and...
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Tài liệu Báo cáo khoa học: Final steps in the catabolism of nicotine Deamination versus demethylation of c-N-methylaminobutyrate doc
Ngày tải lên :
19/02/2014, 07:20
... expression of these genes depends on the presence of nicotine in the growth medium and we have determined the enzyme activities of the proteins Our results demonstrate the presence of two pathways of ... representation of the pAO1 gene and ORF cluster flanked by Tn554 and DTn The cluster consists of the pmfR gene, encoding the regulator of the purU-mabO-folD operon, a permease-like ORF, the genes of the ... specific for the oxidative deamination of the secondary amine of CH3-4-aminobutyrate Apparently there was a selective pressure during the establishment of nicotine catabolism for the evolution of new...
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THE SEWERAGE OF SEA COAST TOWNS doc
Ngày tải lên :
07/03/2014, 20:20
... in the depths of the oceans and the outlines of the coast, the geographical distribution of the water over the face of the globe and the position and declivity of the shores greatly modify the ... in level of the top of the weir and the sill of the notch In using it the rod of the hook-gauge is held against the side of the gauge-peg and lowered into the water until the point of the hook ... is submerged The gauge is then gently raised until the point of the hook breaks the surface of the water, when the distance from the top of the gauge-peg to the top of the rod of the hook-gauge...
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The Fundamentals of Literacy Coaching docx
Ngày tải lên :
08/03/2014, 16:20
... guide the efforts of literacy coaches and the administrators who oversee their work These experiences, the excitement and satisfaction we have found in xxi THE FUNDAMENTALS OF LITERACY COACHING them, ... to work out the model’s kinks and to compare the four targeted schools to the rest THE FUNDAMENTALS OF LITERACY COACHING Maelou realized early on that coaching had to be a part of the plan For ... to their best for their students but not always knowing what the best was These teachers needed a critical, supportive friend to stand beside them and help them be their best Choose the Right Coach...
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The Management of Natural Coastal Carbon Sinks docx
Ngày tải lên :
23/03/2014, 23:21
... The designa on of geographical en es in this book, and the presenta on of the material, not imply the expression of any opinion whatsoever on the part of IUCN, WCPA, Natural England, the ... por on of the diet of the invertebrate fauna (e.g., amphipods, gastropods, polychaetes) that form the base of the marsh food chain Another o en overlooked por on of primary produc vity is the belowground ... of the size of the standing biomass of kelp and associated understory algae This means that the limit of carbon storage in these systems will be a direct func on of the amount and condi on of...
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Coaching That Counts Harnessing the Power of Leadership Coaching to Deliver Strategic Value pdf
Ngày tải lên :
24/03/2014, 00:21
... parts First, the senior partners of the firm would be interviewed to understand the value they expect from coaching If beauty is in the eye of the beholder, then value is in the eye of the senior ... challenge coaches to take them there The second part of this book shifts to the analytic aspect of coaching We take a hard look at these coaching relationships and make sure they are delivering the ... Defining the Space for Coaching 19 and develop with or without the support of a coach As a coach, one of the most rewarding moments in a coaching engagement is the time when the client starts to coach...
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The Power of Self-Coaching The Five Essential Steps to Creating the Life You Want pot
Ngày tải lên :
31/03/2014, 15:21
... quick fix, they’re left with the tedious work of figuring out why they what they And by this time they’re months into therapy and still acting like the same old wretch What can they do? They’ve already ... infatuation period where just being in the psychologist’s presence sends them off feeling the best I’ve felt in years” and touting the amazing benefits of therapy Then, as the sessions progress, things ... 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright...
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coaching that counts harnessing the power of leadership coaching to deliver strategic value 2005
Ngày tải lên :
04/06/2014, 13:20
... parts First, the senior partners of the firm would be interviewed to understand the value they expect from coaching If beauty is in the eye of the beholder, then value is in the eye of the senior ... challenge coaches to take them there The second part of this book shifts to the analytic aspect of coaching We take a hard look at these coaching relationships and make sure they are delivering the ... Defining the Space for Coaching 19 and develop with or without the support of a coach As a coach, one of the most rewarding moments in a coaching engagement is the time when the client starts to coach...
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Báo cáo khoa học: " The role of marine salt and surfactants in the decline of Tyrrhenian coastal vegetation in Italy" ppt
Ngày tải lên :
08/08/2014, 19:21
... Finally, the comparison between the different behaviour of the species tested suggests that resistance to the action of aerosols is the result of the strength of the structures protecting the leaf, ... that is most probably the closest to the original ratio in the aerosol is that recorded in the rainwater gathered near the coastline, ie the one closest to the source Here the MBAS/Cl ratio is ... reproduction of the damage In the st experiment P pinea appeared to be quite susceptible to the absorption and accumulation of NaCl The levels of Cl in the pine needles are related to the concentration of...
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Democratic action party of malaysia and the politics of opposition coalition building
Ngày tải lên :
04/10/2015, 10:26
... least to the extent that differentiated them from the BN component parties Nonetheless, the enigma of the opposition coalition is ironically the juxtaposition of the DAP and the PAS on the same ... to the logical extension of the study to include the exit of the DAP from the BA An early exit could be due to either the flaws in coalition building, hence the inevitability of parting, or the ... study of DAP’s involvement with the opposition coalition can be obtained Sacrificing the parsimony of general modeling of political coalitions, the explanatory powers of the specific incident of coalition,...
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Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
Ngày tải lên :
14/02/2014, 22:20
... the carboxylation of acetyl- CoA to form malonyl -CoA, catalyzed by ACC – the key regulatory enzyme in the pathway Malonyl -CoA serves as the basic chain-elongating substrate for the formation of ... malonyl -CoA concentration in the short-term [27] Aside from the public health aspects of the affects of fructose on food intake, these findings lend further support to the mechanism by which malonyl -CoA ... malonyl -CoA levels [13,23,28,30–33] The genetic evidence for the role of AMPK in the hypothalamus is less clear because the loss of the AMPKa2 subunit in specific hypothalamic cell types resulted in the...
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Tài liệu Báo cáo khoa học: Molecular defect of isovaleryl-CoA dehydrogenase in the skunk mutant of silkworm, Bombyx mori ppt
Ngày tải lên :
18/02/2014, 04:20
... IV -CoA IB -CoA HX -CoA Fig Relative enzymatic activities of wild-type (wt) and sku-type BmIVD (sku) Enzymatic activities of isovaleryl -CoA (IV -CoA) , isobutyryl -CoA (IB -CoA) and hexanoyl -CoA (HX -CoA) ... motif of Gly–Gly–X–Gly The second glycine of this motif (Gly374) is known to make a hydrogen bond with the pyrophosphate moiety of the FAD of the next monomer in the tetramer [16] However, the ... in IVD, the effect of the mutation was further investigated by molecular modelling Together with the previously reported traits of the sku mutant, the molecular and physiological effects of IVD...
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Tài liệu Báo cáo khoa học: Spectroscopic characterization of a higher plant heme oxygenase isoform-1 from Glycine max (soybean) ) coordination structure of the heme complex and catabolism of heme docx
Ngày tải lên :
19/02/2014, 05:20
... 2, the hyperfine splitting constants of the 15N nucleus of the distal NO and of the 14N nucleus of the proximal His of the GmHO-1 complex are closer to those of the rHO-1 complex than to those of ... of the heme pocket of GmHO-1 might be associated with the smaller values of Kazide for GmHO-1 and SynHO-1, and with the ferric character of the heme The Kimidazole values of the three kinds of ... against the concentration of azide of each solution The intersection point corresponding to the mole fraction of 0.5 of the respective forms gives the amount of azide necessary to attain the equilibrium,...
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Tài liệu Báo cáo khoa học: On the mechanism of action of the antifungal agent propionate Propionyl-CoA inhibits glucose metabolism in Aspergillus nidulans doc
Ngày tải lên :
19/02/2014, 16:20
... concentration of propionyl -CoA is similar in all compartments Formation of acetyl- CoA and propionyl -CoA For the determination of the substrate specificity of acetylCoA synthetase and a putative propionyl -CoA ... transfer the CoA- moiety from succinyl -CoA to acetate or propionate as well as the ability to decompose propionylCoA by the transfer of the CoA- moiety to acetate by the action of a CoA- transferase The ... Inhibition of ATP citrate lyase by acetyl- CoA, propionylCoA and butyryl -CoA was measured by addition of different concentrations of single acyl -CoA to the in vitro assay in the presence of 0.34 mM CoASH...
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Tài liệu Báo cáo khoa học: A novel c-N-methylaminobutyrate demethylating oxidase involved in catabolism of the tobacco alkaloid nicotine by Arthrobacter nicotinovorans pAO1 ppt
Ngày tải lên :
19/02/2014, 16:20
... mutagenesis of the MABO gene The amino acid substitutions in the MABO protein were made with the aid of the Quick Change site-directed mutagenesis kit (Stratagene), according to the instructions of the ... compared with the wild-type enzyme, indicating that the mutation affects the redox behaviour of the flavin cofactor The H67A mutant still exhibited 10% of the activity when compared with the wild-type ... c-N-methylaminobutyrate, a compound generated during the catabolism of nicotine The identification of this enzyme reveals, for the first time, the metabolic fate of the pyrrolidine ring of c-N-methylaminobutyrate oxidase...
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Tài liệu Coaching Manual: The Definitive Guide to the Process, Principles & Skills of Personal Coaching pot
Ngày tải lên :
21/02/2014, 16:20
... position of ‘knowing better’ ➡ The coach assumes they have the best answers for the individual, and they often don’t ➡ The focus is mostly on the thoughts of the coach – this reduces the ability of the ... disapprove of other people because of their hair, clothes, appearance, the words they use, their tone of voice, etc What if a coach disapproves of the person they are coaching? What if they hear of behaviour ... longer, as the coach explores the thoughts and experiences of the coachee at the speed that the coachee is comfortable with Attributes of a good coach Whether you want to develop your coaching...
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Tài liệu The wisdom of coaching: Essential papers in consulting psychology for a world of change pot
Ngày tải lên :
21/02/2014, 16:20
... to get the right coach for the EC situation, there are many other factors beside the coach that will affect the success of the coaching: the readiness of the executive, the support from the boss ... getting down to the real work issues in the context of the organizational system of the business The coach needs to care about the business of the executive's organization as much as the executive ... executive and the organization a focus on building the competence of both the executive and the organization a continual emphasis on the integrity of each member of the partnership and of the coaching...
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Tài liệu Báo cáo Y học: Control of p70 ribosomal protein S6 kinase and acetyl-CoA carboxylase by AMP-activated protein kinase and protein phosphatases in isolated hepatocytes pot
Ngày tải lên :
22/02/2014, 07:20
... supply becomes limiting Therefore, the effect of different activators of AMPK and the effect of inhibitors of protein phosphatases on the amino-acid-induced activation of ACC and p70S6K were examined ... phase in the presence of 20 mM glucose and other substances as indicated in the legends to the Figures Anoxia was obtained by incubating the cells in a 95% N2/5% CO2 gas phase At the end of the incubations, ... Time-course of the effects of rapamycin or AICAr on ACC, p70S6K and AMPK activities The experimental protocol is shown schematically at the top of the figure Hepatocytes were incubated in the presence of...
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Báo cáo khoa học: Estrogen-related receptor a and PGC-1-related coactivator constitute a novel complex mediating the biogenesis of functional mitochondria potx
Ngày tải lên :
06/03/2014, 09:22
... the ERRa– PRC complex is involved in the control of the early phase of the cell cycle This is in accordance with the role played by PRC and ERRa in the transition from the G1 to the S phase of ... regulation of the three thyroid cell lines We investigated the effects of XCT790, a specific inverse agonist of ERRa As controls of the inhibitory effect of XCT790 on ERRa, we used the expression of ERRa-validated ... consumption following the inhibition of ERRa confirmed the effect of this factor on the mitochondrial respiratory chain Inhibition of both members of the ERRa–PRC complex decreased the cellular oxygen...
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