... think for themselves and they will not have to have the book, or someone in the book explain what they are reading to them. So in other words, if a newspaper is written in the book, the reader ... of the greatest benefits of the diary narrative is that the reader is allowed see, and feel the emotional hearts and souls of the emotional characters. This is great because when a character is ... feeling too great and is trying hide something, the readerknows this, and therefore the reader knows everything that is happening; nothing is being hidden from the reader. An example of this happening...
Ngày tải lên: 21/03/2014, 22:04
... Conditions This section analyzes the initial macro conditions under which the liberalization of the financial sector and the opening of the capital account took place, to assess whether the overall ... provisioning guidelines—and the relatively weak regulatory and supervisory framework was not improved upon. This was compounded by the fact that the resolution of the crisis in the 80s appeared to ... that together accounted for 25 percent of total financial system assets. A total of 24 finance companies were subsequently closed, and nine others merged into two new companies. The crisis led the...
Ngày tải lên: 27/01/2014, 11:20
Tài liệu Báo cáo khoa học: The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis ppt
... specific signal to move into the nucleus either on its own or with the help of an adaptor protein that facilitates entry into or retention in the nucleus – it is possible that the adap- tor protein is more ... form a complex with the nuclear adaptor Fe65 and the histone acetyltransferase Tip60 in order to target to the nucleus [61,62]. Other ICDs function exclusively in the cytoplasm. The adhesion protein ... from the mem- brane. By analyzing microsomes, we showed that the ectodomain is shed into the lumen of vesicles, whereas the C-terminal half, which possesses the RING finger, is released to the cytoplasm....
Ngày tải lên: 18/02/2014, 08:20
Báo cáo khoa học: Structure of Streptococcus agalactiae serine⁄threonine phosphatase The subdomain conformation is coupled to the binding of a third metal ion pptx
... structure. The phosphate is bound indirectly to the metal ions via water molecules and the Wn–P–O angle (146°) is rea- sonably close to optimal when the roughness of the analysis is taken into account. SaSTP ... bind directly to M3. Asn160 is, however, the closest flap domain resi- due to the M3 binding site. Because the M3 binding site is linked to the conformation of the flap, M3 might also exist in eukaryotic ... coordinates) due to the poor quality of the maps, and refinement with refmac5 [29] stalled at R-factors of 26 and 30%. This may be due to real disorder in the crystal as the mean B-factor from the refinement...
Ngày tải lên: 07/03/2014, 09:20
Economic Effects of Reducing the Fiscal Restraint That Is Scheduled to Occur in 2013 docx
... Feedbac k Total Deficit Factors Contributing to the Change in the Change in the Deficit Contribution of Economic Feedback to the ECONOMIC EFFECTS OF REDUCING THE FISCAL RESTRAINT THAT IS SCHEDULED TO ... estimate is smaller than the change in the automatic stabilizers from 2012 to 2013 that is presented in Table C-2 of The Budget and Economic Outlook: Fiscal Years 2012 to 2022. The change in the ... to the size of the economy means that further substan- tial increases in debt would be especially risky in this regard. Therefore, eliminating or reducing the fiscal restraint scheduled to...
Ngày tải lên: 15/03/2014, 20:20
Báo cáo khoa học: MPP3 is recruited to the MPP5 protein scaffold at the retinal outer limiting membrane ppt
... retinal pigment epithelium faces the subretinal space. The inner and outer segments adjacent to the OLM are the most apical side of photoreceptors and extend into the sub- retinal space. The OLM contains ... Genetics, The Netherlands Institute for Neurosciences (NIN), KNAW, Amsterdam, The Netherlands Polarized cells, like epithelia, photoreceptors and other neurones, establish and maintain unequal distribution of ... up the struc- ture of the molecules and allowing their intermolecular binding. This mediator might be missing in the retina or is competed out by another protein that does not facilitate the...
Ngày tải lên: 16/03/2014, 13:20
Báo cáo khoa học: LIN54 is an essential core subunit of the DREAM / LINC complex that binds to the cdc2 promoter in a sequence-specific manner ppt
... previously that the depletion of LIN9 in human cells inhibits proliferation and results in delayed entry into mitosis [9]. To address whether this is an isolated function of LIN9 or whether it is medi- ated ... with the indicated antibodies before the addition of the probe. The a-LIN9 antiserum has been described previously [12]. The LIN54 antiserum was raised in rabbits against the peptide AAKTKLSSQISDLLTR. ... mitosis and cytokinesis. Interestingly, all tso1 mutants that have been described harbor point muta- tions in the CXC domain, indicating that this domain is critical for the function of this...
Ngày tải lên: 23/03/2014, 04:20
The IRS Receivables Balance Is Based on Data Maintained for Collection Purpoeee_part1 pdf
Ngày tải lên: 20/06/2014, 06:20
The IRS Receivables Balance Is Based on Data Maintained for Collection Purpoeee_part2 potx
Ngày tải lên: 20/06/2014, 06:20
The IRS Receivables Balance Is Based on Data Maintained for Collection Purpoeee_part3 potx
Ngày tải lên: 20/06/2014, 06:20
The IRS Receivables Balance Is Based on Data Maintained for Collection Purpoeee_part4 pptx
Ngày tải lên: 20/06/2014, 06:20
Metaphor, based on the association of similarity, is one of the two basic types of semantic transference that have been an interest for many linguistic researchers
... certain place to another, is used to refer to the meaning “ dismissing as a lover”. In the second example, the action “ crying” is transferred to another An investigation into the role of metaphor ... Aims of the study This study aims to investigate the characteristics of metaphor in poetry from a systemic functional perspective. The objective of the study is: - To examine the characteristics ... which they are involved? + The MODE OF DISCOURSE concerns what part the language is playing, what it is that the participants are expecting the language to do for them in that situation, the symbolic...
Ngày tải lên: 07/11/2012, 14:44
Tài liệu [ Team LiB ] Configuring Your Safe Senders List The Safe Senders list is part of the Junk E-mail pdf
... Safe Senders List The Safe Senders list is part of the Junk E-mail filters. If you choose to allow external content from addresses listed in your Safe Senders list, you need to check the configuration ... select Add Sender to Safe Senders List or Add the Domain @[domain-name] to Safe Senders List. The sender's fully qualified domain name is listed in the menu selection, as shown previously ... Open your Safe Senders list using Tools, Options, Preferences, Junk E-mail and select the Safe Senders tab (see Figure 8.5 ). Near the bottom of the dialog is an option to Also Trust E-mail from...
Ngày tải lên: 21/01/2014, 02:20
Tài liệu The Turner Review: A regulatory response to the global banking crisis pdf
... wrong? 11 It is important to root decisions about the required regulatory response in a clear analysis of the causes of the crisis. This chapter presents that analysis in four sections: • The global story: ... players. If this is the case, which it certainly was in the financial crisis, VAR measures of risk may not only fail adequately to warn of rising risk, but may convey the message that risk is low and ... resilience, the development of securitised credit has ended up producing the worst financial crisis for a century. The crucial issue is whether increased instability is inherent to a securitised model...
Ngày tải lên: 16/02/2014, 11:20
Báo cáo khoa học: The stop transfer sequence of the human UDPglucuronosyltransferase 1A determines localization to the endoplasmic reticulum by both static retention and retrieval mechanisms docx
... yeast were shown to serve as specific ER retention signals. The mechanism is based on the KDEL receptor, which binds the escaped proteins in the Golgi complex and returns them back to the ER [3]. For ... escaped from the ER compartment and moved forward to the distal organelles in the secretory pathway, whereas the other part was retained in the ER. This result A B Fig. 4. TMD of UGT1A stop transfer sequence ... us to suggest that the membrane assembly of UGT1A6 may involve several topogenic elements [17]. This prompted us to investigate the topogenic role of the stop transfer sequence, which comprises...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx
... ([Ile8]oxytocin) are the evolutionary precursors of oxytocin [1]. The receptors that mediate the effects of these hormones are G-protein coupled receptors (GPCRs) and include the isotocin receptor, the ... other members of the neurohypophysial hormone receptor family; for example, the distal N-terminus is required for agonist binding to the OTR [11,12] and also to the vasotocin receptor [13], suggesting ... decreasing agonist affinity and (b) promoting the agonist-induced active conformation due to the loss of a stabilizing constraint on the ground state of the receptor. Therefore, the agonist had a lower...
Ngày tải lên: 07/03/2014, 21:20
The Awassi sheep with special reference to the improved dairy type potx
... west of the Tigris to the region of Mosul. The breed is also widespread east of the Tigris, north of the lower DiyƗlá and Baghdad, in the pastoral region stretching intermittently into the Mosul ... months of the year is their fleeces, the pigment of their heads and their habit of keeping their heads in the shade below the bellies of their flock mates. It is only from the cold storms of ... of the scrotum. These glands serve to keep the skin of the udder oily and pliant. In an examination of the anatomy of the circulatory system of the Awassi ewe's udder, Perk and This is...
Ngày tải lên: 18/03/2014, 00:20
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