... at the sn-2 position of the phospholipid, this proton is donated by the imidazole ring to the oxygen, which then forms the alcohol group of the lysophospholipid to be released together with the ... representation of the catalysis mechanism proposed for the PLA2s Interaction of the residues from the catalytic site of sPLA2s and the calcium ion with the transition state of the catalytic reaction ... polarized by the His48 and Asp99 residues binds to the carbonyl group of the substrate [18] The substitution of the Asp49 residue by the Lys49 significantly alters the binding site of Ca2+ in the phospholipase...
Ngày tải lên: 31/08/2014, 08:57
The alchemy of meta-analysis
... longer applies once they are pooled So if they conflict, the results of meta -analysis, despite the fanciness of the word, should never be privileged over a large RCT In the case of the example above, ... move from the 50% mark closer to the 100% mark Depending on the strength of the scientific literature, the quality of the studies, the amount of replication, and our own interpretation of that ... probability thus: The probability of any event is the ratio between the value at which an expectation depending on the happening of the event ought to be computed, and the value of the thing expected...
Ngày tải lên: 01/11/2013, 11:20
... charactertstic of an equilibrium, such as the vapour pressure of a liquid, the solubility of a solid, or the equilibrium constant of a reaction Then some of the most useful results of thermodynamics are of ... determined by the relative speeds of these two reactions on the surface of the catalyst It is therefore a problem of rates and not of equilibria The theory of equilibria, based on thermodynamics, ... regarding thermodynamics as having its own secure empirical basis On the other hand, the laws of thermodynamics may themselves be interpreted in terms of the fine structure of matter, by the methods of...
Ngày tải lên: 12/02/2014, 16:20
Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders ppt
... endorsement by the U.S Department of Justice The National Institute of Justice is a component of the Office of Justice Programs, which also includes the Bureau of Justice Assistance, the Bureau of Justice ... into the organic phase of the microemulsion Once dissolved, the agent can react with the water-soluble decontaminant at the surface of the organic portion of the microemulsion The rate of agent ... Statistics, the Office of Juvenile Justice and Delinquency Prevention, and the Office for Victims of Crime U.S Department of Justice Office of Justice Programs National Institute of Justice Guide for the...
Ngày tải lên: 23/03/2014, 23:20
Guide for the Selection of Chemical and Biological Decontamination Equipment for Emergency First Responders pdf
... endorsement by the U.S Department of Justice The National Institute of Justice is a component of the Office of Justice Programs, which also includes the Bureau of Justice Assistance, the Bureau of Justice ... Statistics, the Office of Juvenile Justice and Delinquency Prevention, and the Office for Victims of Crime U.S Department of Justice Office of Justice Programs National Institute of Justice Guide for the ... Opinions or points of view expressed in this document represent a consensus of the authors and not necessarily represent the official position or policies of the U.S Department of Justice The products...
Ngày tải lên: 23/03/2014, 23:20
Báo cáo sinh học: " The role of mutational analysis of KIT and PDGFRA in gastrointestinal stromal tumors in a clinical setting" doc
... died of the disease and three were still alive at the end of the follow-up (370 months) The authors concluded that 83% of GIST with PDGFRA mutations have a good prognosis [27] The same group of ... mutation of tyrosine kinase receptors is a mechanism of drug resistance occurring either at the beginning of treatment (primary resistance) or during the course of therapy (secondary resistance) The ... and 2002 The primary endpoint of the study was RFS and the patients were randomized to receive imatinib at the two doses with the possibility of cross over to the higher doses in case of progressive...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" The role of mutational analysis of KIT and PDGFRA in gastrointestinal stromal tumors in a clinical setting" docx
... died of the disease and three were still alive at the end of the follow-up (370 months) The authors concluded that 83% of GIST with PDGFRA mutations have a good prognosis [27] The same group of ... mutation of tyrosine kinase receptors is a mechanism of drug resistance occurring either at the beginning of treatment (primary resistance) or during the course of therapy (secondary resistance) The ... and 2002 The primary endpoint of the study was RFS and the patients were randomized to receive imatinib at the two doses with the possibility of cross over to the higher doses in case of progressive...
Ngày tải lên: 20/06/2014, 03:20
The Martians of Chemical Heritage Five Physicists Who Changed the Theodore Century pot
... because of the Nazi takeover Regardless of whether they had converted to other religions, they never shied away from their Jewishness They also proudly maintained their Hungarian identity Some of them ... applications of symmetry principles to atomic physics Von Neumann was the father of the modern computer and Teller the father of the hydrogen bomb The American hydrogen bomb saved the world from the Soviet ... to the otherwise growing awareness of the importance of athleticism and sports for the healthy development of the individual John Lukacs, a historian of the Budapest of around 1900, noted the...
Ngày tải lên: 27/06/2014, 08:20
The Elements of Blowpipe Analysis, by Frederick Hutton Getman doc
... before the Blowpipe Ores of Antimony Ores of Arsenic Ores of Bismuth Ores of Chromium Ores of Cobalt Ores of Copper Ores of Iron Ores of Lead Ores of Manganese Ores of Mercury Ores of Nickel Ores of ... Blowpipe. The common blowpipe of the jeweller is not particularly well suited to the operations of blowpipe analysis, since the flame has often to be kept playing upon the assay for some time, and the ... moisture of the breath would seriously interfere with the passage of the air through the jet One of the best and least expensive forms of blowpipe is shown in Fig This consists, as is seen from the...
Ngày tải lên: 28/06/2014, 19:20
the engineering of chemical reactions
... ethylene per mole of ethane fed (the yield of the process is 80%) What is the cash flow of the process? What must be the cost of producing ethylene if we want a profit of 10% of sales? 1.9 What ... typical chemical processes the capital and operating costs of the reactor may be only 10 to 25% of the total, with separation units dominating the size and cost of the process Yet the performance of ... principles of operation of chemical equipment rather than just memorize pictures of them Only in the Process Design course does there remain much discussion of the processes by which chemicals...
Ngày tải lên: 06/07/2014, 15:31
the engineering of chemical reactions
... ethylene per mole of ethane fed (the yield of the process is 80%) What is the cash flow of the process? What must be the cost of producing ethylene if we want a profit of 10% of sales? 1.9 What ... typical chemical processes the capital and operating costs of the reactor may be only 10 to 25% of the total, with separation units dominating the size and cost of the process Yet the performance of ... principles of operation of chemical equipment rather than just memorize pictures of them Only in the Process Design course does there remain much discussion of the processes by which chemicals...
Ngày tải lên: 06/07/2014, 15:34
Báo cáo y học: "Complex systems and the technology of variability analysis" ppsx
... plot of the log of the power of earthquakes (i.e the Richter scale) against the log of the frequency of their occurrence reveals a straight line with negative slope of -1 Thus, the probability of ... periodicity Note that the square of the contribution of each frequency is the power of that frequency to the total spectrum, and the total power of spectral analysis (area under the curve of the power spectrum) ... to the square root of variance; and variance is equal to the sum of the squares of difference from the mean, divided by the number of degrees of freedom Evaluating HRV, the standard deviation of...
Ngày tải lên: 12/08/2014, 20:20
Development and applications of novel solvent minimized techniques in the determination of chemical warfare agents and their degradation products
... on the analysis results that contains analytical proof of the presence of chemicals reported and provides high certainty of the absence of other chemicals relevant for the implementation of the ... from the Organic Synthesis Group for providing the analytes used in the study and all users of the GC MSD for sharing the use of the instrument Even though people come and go, the memories of the ... can be used in place of LLE in the ROPs for sample treatment of aqueous samples for the analysis of CWC-related chemicals [62] 1.8 Motivation of the Project The objective of the project is to improve...
Ngày tải lên: 14/09/2015, 14:08
Testing the profitability of technical analysis in singapore and malaysian stock markets
... called the neckline, drawn across the bottoms of the declines on both sides of the head The break out is confirmed when the stock price closes k percent below the neckline The break out of the head-andshoulders ... to the other traders (non-chartists) The Group of Thirty [26] surveyed the views of market participants on the functioning of the foreign exchange market in 1985 The respondents were composed of ... countries The survey results indicated that 97% of bank respondents and 87% of the securities houses believed that the use of Technical Analysis had a significant impact on the market The Group of Thirty...
Ngày tải lên: 16/10/2015, 11:58
The Economics of InputOutput Analysis
... shadow price of λi is assigned to the entity of constraint i, then the value of the ith bound is λi bi and the total value of bound b exhausts the value of the objective function Since the shadow ... By (1.38) the shadow prices of the materials are simply equal to the world prices And by (1.37) the prices are equal to the sum of the material costs of the inputs, the capital costs, the labor ... with the same number of rows as of columns; we say it is n×n-dimensional, where the first n refers to the number of rows (i.e the length of the columns) and the second n refers to the number of...
Ngày tải lên: 06/04/2016, 17:57
Tài liệu Báo cáo khoa học: Influence of modulated structural dynamics on the kinetics of a-chymotrypsin catalysis Insights through chemical glycosylation, molecular dynamics and domain motion analysis pptx
... some of these phenomena may be interconnected within the catalytic mechanism of the enzyme Structural insights into the mechanochemical nature of a-CT catalysis A more detailed analysis of the ... cutoff distance (rc ẳ 6.0 A) The dynamics of the resulting network are then dened by the Ni ã Nj Kirchhoff connectivity matrix of interresidue contacts (G) where the off diagonal elements of ... excluded from the experiments to simplify the analysis of the results because preliminary experiments revealed that the binding of calcium to the protein surface was perturbed by the chemical glycosylation...
Ngày tải lên: 19/02/2014, 05:20
Báo cáo khoa học: "Quantitative physico-chemical analysis of the acidosis of cardiac arres" ppsx
... 10% of the patients had witnessed arrest It is not surprising that the initial rhythm in more than 50% of the study patients was asystole Nineteen percent of the arrest group had a return of spontaneous ... to the metabolic acidosis in equal amounts to that of lactate The presence of unmeasured ions alters the clinical interpretation and treatment of the patient This study has identified another ... area that needs further investigation to determine the significance of the presence of unmeasured ions in the postarrest patient Competing interests The author(s) declare that they have no competing...
Ngày tải lên: 12/08/2014, 22:22
Báo cáo y học: " Laugh Yourself into a Healthier Person: A Cross Cultural Analysis of the Effects of Varying Levels of Laughter on Health"
... both extremes of the emotional spectrum were shown At the end of the videos, the brachial artery constricted for five minutes and was then released In fourteen of the twenty volunteers the artery ... expression (27) Therefore, the crux of individualism is the ethnic diversity of various individuals It is not the particular view of the individual that makes them an individualist, but it is the differing ... conditions, and then to specify the name of that condition If the participant failed to indicate the name of the condition regardless of a “yes”, the survey was discarded assuming the participant...
Ngày tải lên: 26/10/2012, 09:57
Báo cáo y học: "Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the MultiFunction-CardioGramsm or MCG (a.k.a. 3DMP), to Quantitative Coronary Angiography for the Detection of Relevant Coronary Artery Stenosis (70%)
... large inventory of normalized mathematical indexes of abnormality It is the pattern of these mathematical indexes of abnormality, obtained from analysis of multiple cardiac cycles of the resting ... centers included in the meta -analysis The boundaries of the box are Tukey’s hinges The median is identified by the line inside the box The length of the box is the interquartile range (IQR) computed ... patients had prior revascularization The boundaries of the box are Tukey’s hinges The median is identified by the line inside the box The length of the box is the interquartile range (IQR) computed...
Ngày tải lên: 03/11/2012, 10:58