... on the binding of HB-19 Similarly, the iron-binding hTf had no effect On the other hand, bLf inhibited the binding of HB-19 to cells In accordance with the involvement of both lobes of hLf in the ... nucleolin, the bLf N-t and, at a somewhat lower extent, the bLf C-t, were also inhibitory (Fig 6B) These observations further confirm the interaction of Lf with surface nucleolin and illustrate that the ... Numbers at the ends of the strips correspond to the first and last amino acid residues of polypeptides The dotted lines show the approximate locations of the four structural domains: N1 and N2 domains...
Ngày tải lên: 07/03/2014, 15:20
... “A” and “B” adapters are ligated to the blunt ends using DNA ligase • The strands are denatured using sodium hydroxide to release the ssDNA template library (sstDNA) The Adapters • The A and ... for both amplification and sequencing since their composition is known • The B adapter contains a 5’ biotin tag used for mobilization • The beads are magnetized and attract the biotin in the ... to the number of nucleotides incorporated • Therefore, if the intensity of a single read is times the intensity of a previous read, there are times the amount of incorporated nucleotides in the...
Ngày tải lên: 19/03/2014, 22:32
Báo cáo khoa học: Sulfated polysaccharides inhibit the catabolism and loss of both large and small proteoglycans in explant cultures of tendon doc
... polyxylan that has been shown to modify both the symptoms and the progression of osteoarthritis in both humans and animals [21] We and others have shown that the calcium salt of pentosan polysulfate ... shows that the rate of [35S]sulfate appearing in the medium was suppressed by the inclusion of the sulfated polysaccharides At the end of the culture period, both CaPPS and heparin reduced the appearance ... and it is therefore likely that the outcome of the inhibition of aggrecanase activity in tendon is the retention of large proteoglycans within the extracellular matrix of the tissue [22–27] The...
Ngày tải lên: 23/03/2014, 10:21
Báo cáo khoa học: Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm pdf
... between the two enzymes, showed no correlation between their nuclear localization and CREB-repression activities On the other hand, both the nuclear and cytoplasmic SIK1 mutants inhibited the ACTH-induced ... distributed diffusely both to the nucleus and to the cytoplasm of resting Y1 cells On the other hand, SIK1(I607A/L610A) was localized mainly in the cytoplasm These findings suggest that these hydrophobic ... of the N-terminal regions and of the C-terminal regions were separately amplified by PCR and then ligated to these fragments To amplify fragments containing residues 1–572, 1–585 and 1–612, the...
Ngày tải lên: 30/03/2014, 15:20
american gridlock why the right and left are both wrong commonsense 101 solutions to the economic crises
... hastened the end of civilized discussion as the gulf between the Left and Right grew, and as the attacks of the one on the other grew ever more vitriolic Much of what happened reflected the way ... rhetoric of the opposite party This development in turn has widened the gulf between Left and Right and thereby amplified the Dialogue of the Deaf Alas, the Media Was the Message As these developments ... more irrational both parties become in pressing their claims In practice, the further downstream politicians and their staffers enjoin the debate, the more they tend to substitute their own biased...
Ngày tải lên: 29/05/2014, 14:01
market efficiency and market anomalies three essays investigating the opinions and behavior of finance professors both as researchers and as investors
... their theoretical model The χ2 statistic, however, can be misleading depending on the complexity of the model (the more complex the model, the better the fit), the size of the sample (the larger the ... efficiency and advances in asset pricing As I develop the theory, I explain the necessary conditions and then discuss the empirical implications of the model The results ultimately corroborate the theory ... determine whether the overall fit of the model is adequate and whether the latent variables are reliably reflected by the observed variables selected to manifest them in the model The χ2 from the model...
Ngày tải lên: 03/06/2014, 02:06
morewood - 1824 - an essay on the inventions and customs of both ancients and moderns in the use of inebriating liquors
Ngày tải lên: 12/06/2014, 11:29
Báo cáo khoa học: " Differential protection by wildtype vs. organelle-specific Bcl-2 suggests a combined requirement of both the ER and mitochondria in ceramide-mediated caspase-independent programmed cell death" docx
... both mitochondria and the ER, Bcl-2 ActA targeted to mitochondria, Bcl-2 cb5 expressed at the ER, and Bcl-2 ΔTM localized in the cytosol The Bcl-2 homology domains BH1-BH4 are indicated together ... critical reagents and participated in the design of the study DA conceived and designed the experiments, analyzed data and wrote the paper All authors read and approved the final manuscript Acknowledgements ... cells with TNF in combination with the broad-spectrum caspase-inhibitor zVAD and the protein biosynthesis inhibitor CHX (to sensitize the cells) and compared their survival to a Jurkat cell line...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "Recovery of fitness of a live attenuated simian immunodeficiency virus through compensation in both the coding and non-coding regions of the viral genome" pot
... the DIS and in the NC protein The results of Fig 4B show that either the E18G or G31K substitution in NC was independently able to facilitate complete Pr55Gag processing in the SD2 virus In the ... mutations in the DIS (A423G), and NC (E18G and G31K) regions Next, we tested the ability of the two NC mutations to restore vRNA incorporation Fig 2B shows that the presence in SD2 of either E18G ... in Materials and Methods A Non-denaturing Northern analysis of the SD2 variant in conjunction with compensatory mutants in the DIS, CA, and p6 B Non-denaturingNorthern analysis of the SD2 variant...
Ngày tải lên: 13/08/2014, 05:22
not only..but also/ both...and/ either/ neither
... ngữ mệnh đề theo sau Not only: Ex: It is not only the cheapest but also the nicest watch Not only is it the cheapest but it is also the nicest watch Either… or/ Neither ….nor Either ….or dung ... / Nither …nor chia theo chủ từ gần (chủ từ phía sau) - I came there to meet either him or her father - We intend either to go to the beach or to go on a picnic - I like either reading book or ... kia, hay Theo sau N/ Pronoun (làm chủ từ hay túc từ); Động từ nguyên mẫu hay danh động từ Ex: - Either he or I have to go to the meeting this afternoon Động từ theo sau Either…or / Nither …nor...
Ngày tải lên: 14/05/2015, 01:00
EXERCISES ON “BOTH ... AND, EITHER .. OR, NOT ONLY ... BUT ALSO, NEITHER ... NOR”
... 16 Neither my brother my mother knows about this A both B either C and D nor 17 I felt happy and sad at the same time A both B neither C either D not only 18 of the ... your friends A both – and B either – or C neither – nor D not only – but also 15 I will take you _ to the cinema _ to the theatre That's a promise A both – and B either – or C neither – nor D ... playing football and so I (both and) She didn’t say a word and she didn’t smile (neither nor) The English team didn’t play well and the Scottish team didn’t play well, either (neither nor) He...
Ngày tải lên: 18/05/2015, 12:00
EITHER NEITHER BOTH AND
... trúc ởđầu câu: Both my father and my mother … Đoạn sau giống ta gom lại: => Both my father and my mother like dogs - Động từ theo sau both … and số nhiều: Both her father and mother are pround ... mountain and he can’t EITHER I wasn’t at the beauty contest and NEITHER was she Thuy didn’t have her hair cut, NEITHER did her brother A: I shan’t go overseas next month B: I shant’t EITHER/ NEITHER ... liên từ) b) Những trường hợp cá biệt: i) EITHER…OR… NEITHER NOR… - EITHER NEITHER liên từ, khác với EITHER NEITHER tính từ chỗ danh từ sau EITHER…OR… NEITHER NOR… có mạo từ xác định, hay không xác...
Ngày tải lên: 23/05/2015, 00:00
EITHER-NEITHER-BOTH...AND...
... didn’t either B Neither did I C Neither will I 10 They won’t buy a new car A I might either B Neither will I C I must either 11 Stan isn’t at work right now A Neither will I B Neither am I C Neither ... would not D I don’t either D Neither would I D And I might not D Neither I D And I am either! D I am not either D I can’t either D Neither I D Neither I D I am not either THE END -Page ... A Either B Not C So D Neither I left it on the table in the drawer A either – nor B neither – or C either – or D either – either the radio the television works properly A Neither...
Ngày tải lên: 28/05/2015, 08:00
bai tap neither...nor, either...or,both...and
... didn’t either B Neither did I C Neither will I 10 They won’t buy a new car A I might either B Neither will I C I must either 11 Stan isn’t at work right now A Neither will I B Neither am I C Neither ... would not D I don’t either D Neither would I D And I might not D Neither I D And I am either! D I am not either D I can’t either D Neither I D Neither I D I am not either THE END -Page ... A Either B Not C So D Neither I left it on the table in the drawer A either – nor B neither – or C either – or D either – either the radio the television works properly A Neither...
Ngày tải lên: 07/06/2015, 03:00
Bai tap ve Either...or,neither...nor,both...and,not only.....but also
... Neither ……………………………………………………………………… Mary hasn’t studied Spanish Her friend hasn’t studied Spanish => Neither ……………………………………………………………………… 10 They didn’t like music They didn’t like sports => They ... He doesn’t like to go on foot => Dick doesn’t either …………………………………………………………… They won’t come here tomorrow They won’t stay at home => They won’t either …………………………………………………………… I didn’t have to ... => Neither He not only read the book but also remembered what he had read => Not only She can’t write fast She can’t type => She can’t either ………………………………………………………………...
Ngày tải lên: 27/06/2015, 04:00
Both either and neither
... either b) neither c) both Answers I didn’t like either of these two dresses I like neither of these Have you got another one? Both of them have been invited I have invited neither / both of them ... a) either b) neither c) both ‘I know you don’t like me I don’t like you ……………….’ a) either b) neither c) both ………………… Martin nor James turned up today a) either b) neither c) both 10 She ... different.) I haven’t invited either of them They were both eager to hear the news Both Martin and James are brilliant boys ‘I know you don’t like me I don’t like you either.’ Neither Martin nor James...
Ngày tải lên: 11/07/2015, 09:20
Chủ đề 11 Either or/ Neither nor/ Both and/ Not only but also
Ngày tải lên: 13/11/2015, 10:03
The Design and Implementation of a Log-Structured File System
... writes, then reads the file back sequentially, then writes 100 Mbytes randomly to the existing file, then reads 100 Mbytes randomly from the file, and finally reads the file sequentially again The bandwidth ... for the log can be generated either by copying the old blocks or by threading the log around the old blocks The left side of the figure shows the threaded log approach where the log skips over the ... delay the cleaning a while and let more of the blocks die in the current segment The value of a segment’s free space is based on the stability of the data in the segment Unfortunately, the stability...
Ngày tải lên: 12/09/2012, 15:05
The Breadth and Depth of DSP
... controlling and mixing the signals in these many elements, the sonar system can steer the emitted pulse to the desired location and determine the direction that echoes are received from To handle these ... transferring their customer's information, while they must pay to establish and maintain the channel The financial bottom line is simple: the more information they can pass through a single channel, the ... generation and recognition are used to communicate between humans and machines Rather than using your hands and eyes, you use your mouth and ears This is very convenient when your hands and eyes...
Ngày tải lên: 13/09/2012, 09:49