... trafficking of the CD95 from inside the hepatocyte to the plasma membrane [39], which depends on a ROS-mediated tyrosine phosphorylation of the epidermal growth factor (EGF)-receptor, the association of ... activates the CD95 system, which localizes downstream of the ROS production triggered by Osmosensing and signaling in mammalian cell function Fig Hepatocyte shrinkage and the production of reactive ... apoptosis include activation of the protein kinase B survival pathway [31], p53 activation [32], induction of the serum- and glucocorticoidinducible kinase Sgk [33], expression of the heat shock protein...
Ngày tải lên: 18/02/2014, 16:20
... tissues The analysis of the DNA of different Conus species has already revealed a large number of a-conotoxin sequences [45] and the identification of further specific nAChR ligands is likely The advantage ... mentioned above, the determination of the subunit composition of the nAChRs involved has been hindered by the lack of selective ligands and imperfect correlations between the characteristics of native ... Furthermore, the distance of the projection areas from the cell bodies and the indistinct correlation between subunit mRNA levels and functional surface nAChRs hampers the interpretation of studies...
Ngày tải lên: 19/02/2014, 12:20
Coaching Standardized Patients For Use in the Assessment of Clinical Competence pot
... Carnovsky, one of the original actors of the Group Theatre, also aptly describes the ideal relationship of the SP coach and the SPs It is the coach’s vision of the patient case that enables the SPs ... see the theme I couldn’t see at the time the longing to express the inexpressible and the need to heal the emotional wounds that are part of being human So I sought the safety of the halls of ... dramatic arts, and the authenticity of our SPs’ performances in the service of training future generations of physicians The origins of drama and the art of acting are the subject of speculation among...
Ngày tải lên: 08/03/2014, 16:20
What is the price of a mousetrap? The assessment of value from cloud services pptx
... cloud health starts with an assessment of value The assessment of value of cloud services can only include a comparison against other cloud providers The comparison of cost between traditional ... AMS is the paradigm where a predefined level of demand is managed internally and the remainder augmented with cloud services The apothegm is ‘Own the base and rent the peak’ Conclusion The customer’s ... simple as a mouse-trap The complication is that for most customers they already have an IT investment So the assessment of cloud value will involve a comparison between what other IT investments...
Ngày tải lên: 09/03/2014, 02:20
THE PERFORMANCE OF CREDIT RATING SYSTEMS IN THE ASSESSMENT OF COLLATERAL USED IN EUROSYSTEM MONETARY POLICY OPERATIONS pot
... to the quantiles of the standard normal distribution The quality of the approximation depends on the values of the parameters N Y,, the number of rated entities with the same rating grade at the ... distribution The mean of this distribution, the probability of default of the benchmark, is estimated at ˆ [0.0%, 0.1%] p (with an average of 0.04%) The other binomial parameter is the number of trials ... participate in the credit assessment of collateral .The authors would like to thank the members of the ECAF Task Force and of the Working Group on Risk Assessment and an anonymous ECB referee for their...
Ngày tải lên: 22/03/2014, 20:20
Báo cáo khoa học: "An Object-Oriented Approach to the Design of Dialogue Management Functionality" doc
... In the prototype system the instances contain, as one of their attributes, specific details of the service they offer: in the case of a Travel Expert instance this will be a schedule; in the ... the place of departure, the destination, the day of departure and the departure time, and if a final check with the instance's database indicates that the combination of data is valid, then the ... narrow the enquiry to one of the areas available Although the system may request specific information (as in the turn above), the user may supply rather more than this Using the heuristics of the...
Ngày tải lên: 24/03/2014, 03:20
The Assessment of Water Quality and Pollution in Tanzania pptx
... extension phases in the 1970s The report also assessed domestic sources of pollution along the coast of Dar es Salaam Another review of the development of the sewerage system of Dar es Salaam was ... on the impact of these wastes on the water quality The majority of the studies carried out so far looked at pollution loads per se and noticeably few have examined the impact of pollutants on the ... have concentrated in the Msimbazi River and Creek and the harbour area, at the expense of other areas The same can be said of Zanzibar and Tanga In Zanzibar, the majority of water quality studies...
Ngày tải lên: 29/03/2014, 21:20
Committee on the assessment of wartime exposure
... secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the responsibility given to the ... estimate of the amount of dioxin likely to have been deposited in the Republic of Vietnam during the war • Refinement of the computational approach of a previously developed EOI and refinement of the ... familiar with the disparate record forms produced by the various branches of the military over the course of the war or have experience working with the bureaucracy that maintains them The aim of Project...
Ngày tải lên: 13/06/2014, 01:23
báo cáo hóa học: " The assessment of health-related quality of life in relation to the body mass index value in the urban population of Belgrade" potx
... of the general quality of life [8-11] Whilst obesity has an obvious and often objectively measurable impact on the state of health of the individual, the influence of increased body weight on the ... daily The second part of the questionnaire consisted of a short version of the SF-36 generic assessment scale for the quality of life, as an internationally accepted questionnaire on health self -assessment, ... other instruments to assess HRQL [36] Our conclusions that increased values of BMI affect the quality of life, and particularly the physical health of the individual, coincide with those of other...
Ngày tải lên: 18/06/2014, 19:20
báo cáo hóa học:" Development and validation of the Impact of Dry Eye on Everyday Life (IDEEL) questionnaire, a patient-reported outcomes (PRO) measure for the assessment of the burden of dry eye on patients" potx
... in the decisions throughout the process of development and finalisation of the questionnaire They gave their approval at each of the milestones of the development and finalisation process The ... evaluation of the burden of the dry eye condition on patients The assumption about the pre-defined structure of the IDEEL as distinct modules and the lack of data from PCA and Multi-trait analyses on the ... The Dry Eye Symptom-Bother module of the IDEEL was the dimensions most highly correlated with all of the DEQ items (0.21–0.83) All the IDEEL correlations showed the lowest correlations with the...
Ngày tải lên: 20/06/2014, 15:20
báo cáo hóa học:" The assessment of health-related quality of life in relation to the body mass index value in the urban population of Belgrade" docx
... of the general quality of life [8-11] Whilst obesity has an obvious and often objectively measurable impact on the state of health of the individual, the influence of increased body weight on the ... daily The second part of the questionnaire consisted of a short version of the SF-36 generic assessment scale for the quality of life, as an internationally accepted questionnaire on health self -assessment, ... other instruments to assess HRQL [36] Our conclusions that increased values of BMI affect the quality of life, and particularly the physical health of the individual, coincide with those of other...
Ngày tải lên: 20/06/2014, 16:20
báo cáo hóa học:" Validation of the Spanish version of the Chronic Pain Acceptance Questionnaire (CPAQ) for the assessment of acceptance in fibromyalgia" pot
... is one of the most used questionnaires for the assessment of depression and anxiety in medical patients We have used the cut-off point recommended in the validated Spanish version of the HADS ... (SF 36), the Pain Catastrophising Score (PCS) and the Fibromyalgia Impact Questionnaire (FIQ) Translation of the CPAQ Two researchers, who were aware of the objectives of the CPAQ, did the first ... calculated according to the recommended 10:1 ratio of the number of subjects to the number of test items [18] The final study sample consisted of 205 patients attending the Pain Clinic (Santander,...
Ngày tải lên: 20/06/2014, 16:20
báo cáo hóa học:" Psychometric evaluation of a visual analog scale for the assessment of anxiety" pdf
... diary format The distance from the left edge of the line to the mark placed by the patient is measured to the nearest millimeter and used in analyses as the patient GAVAS score A number of additional ... indicating better functioning and quality -of- life The Clinician Global Impression of Severity (CGIS) [28] is a single-item rating that asks the clinician to evaluate the severity of the patient's ... illness over a particular time interval, in the present context "since the start of the study." The CGIC, like the CGIS, is completed by the clinician, whereas the PGIC is patient-reported Both items...
Ngày tải lên: 20/06/2014, 16:20
Báo cáo hóa học: " On the stability of an AQCQ-functional equation in random normed spaces" potx
... tnorms In the sequel, we adopt the usual terminology, notations and conventions of the theory of random normed spaces, as in [35-37] Throughout this paper, Δ+ is the space of distribution functions, ... where l- f (x) denotes the left limit of the function f at the point x, that is, l− f (x) = limt →x− f (t) The space Δ+ is partially ordered by the usual point-wise ordering of functions, i.e., F ... (1:2) It is easy to show that the function f(x) = x3 satisfies the functional equation (1.2), which is called a cubic functional equation and every solution of the cubic functional equation is said...
Ngày tải lên: 21/06/2014, 01:20
Báo cáo hóa học: " Research Article A Framework for the Assessment of Temporal Artifacts in Medium Frame-Rate Binary Video Halftones" pot
... reported that the nature of dither is most important in the flat regions of the image [12] This phenomenon is due to the spatial masking effects that hide the presence of noise in regions of the image ... described the form of the function in (1) We have also not described how to calculate the arguments of this function We provide these details next We now describe a particular instantiation of the ... [3] They have called their assessment measure average flicker rate (AFR), which they compute by adding the “on” pixels in the absolute difference image and then dividing the resulting sum by the...
Ngày tải lên: 21/06/2014, 08:20
Báo cáo sinh học: " Research Article Multiplicative Concavity of the Integral of Multiplicatively Concave Functions" pot
... a, b × a, b Lemmas and the Proof of Theorem 1.6 For the sake of readability, we first introduce and establish several lemmas which will be used to predigest the proof of Theorem 1.6 Lemma 2.1 can ... function of log x Modulo this characterization, the class of all multiplicatively convex functions was first considered by Motel , in a beautiful paper discussing the analogues of the notion of ... Journal of Inequalities and Applications Proof of Theorem 1.6 Since f : a, b ⊆ 0, ∞ → 0, ∞ is a continuous multiplicatively concave function, from Lemma 2.9 we know that there exists a sequence of...
Ngày tải lên: 21/06/2014, 17:20
Báo cáo hóa học: " Research Article On the Stability of Generalized Additive Functional Inequalities in Banach Spaces" pdf
... Then by the same reasoning as in the proof of Theorem 2.1, it is proved and so we omit the details b Letting xi x, xj y, by the same reasoning as in the corresponding part of the proof of Theorem ... , , ξn ξn ξn lim |ξ|n ϕ n→∞ 3.39 γz for all x, y, z ∈ X The rest of the proof is the same as in the corresponding part of the proof of Theorem 3.6 Corollary 3.10 Let f : X→Y be a mapping satisfying ... Mathematics, no 8, Interscience, New York, NY, USA, 1960 D H Hyers, “On the stability of the linear functional equation,” Proceedings of the National Academy of Sciences of the United States of...
Ngày tải lên: 22/06/2014, 02:20
Báo cáo hóa học: "Error Sign Feedback as an Alternative to Pilots for the Tracking of FEXT Transfer Functions in Downstream VDSL" pptx
... uses a block of K = 60 000 symbols The output of the algorithm is taken at the end of the K blocks and the performance (in terms of the estimation error, SIR and SNIR) is averaged over the 1000 simulations ... on the various parameters: the constellation sizes of the different users, the interference coefficients themselves, and of course the noise variance Now, another interesting value to compute is the ... samples is Note that because the MCRB is inversely proportional to the gain (28), we actually compute the inverse of the average of the inverse of the gains— that is, the so-called harmonic mean...
Ngày tải lên: 22/06/2014, 23:20
Báo cáo toán học: "On the continuity of non-analytic functional calculi " ppt
Ngày tải lên: 05/08/2014, 10:20
Báo cáo lâm nghiệp: "Forest yield index and its applicability to the assessment of future forest yields" docx
... climate are the main sources of the final error In addition, the low presence of some tree species in the source data set negatively influenced the accuracy of the results Theoretically, the standard ... and each planning unit Hence, the proposed index is more suitable for the assessment of current utilization of the woodproduction potential of forests The assessment of future forest generation ... the current relative utilization of wood-production function of the forests Methodologically, the index is based upon mathematical models of forest growth (stand growth tables), proportions of...
Ngày tải lên: 07/08/2014, 10:21