... life Since they did not know muchabout disease their lack of knowledge of diseases and their lack of medical practitionersin these remote areas would give the perfect opportunity for their superstitious ... suffered by victims of Porphyria they are usually verysensitive to light which would cause them to not venture out of their homes until night.This aspect ofthe lifestyles of people suffering ... stories described the vampires as giving off a greenish glow Victims ofthis disease are likely to be deformed in other ways as well but usually in the facial area.Because ofthe skin lesions suffered...
... established the conditions fortheexistenceof at least two or three positive solutions in these boundary value problems by virtue ofthe Avery-Henderson fixed point theorem and the Leggett-Williams ... to the following discussion Section analytically establishes the criteria fortheexistenceof at least two positive solutions in the boundary value problems 1.9 and 1.10 with the aid ofthe ... conditions C1 – C3 in Theorem 4.2 are satisfied forthe above specified functions and parameters Therefore, in the light of Theorem 4.2, we conclude that the dynamic equation on the specified time scales...
... that there is a large number of functions that satisfy the conditions of Theorem 3.3 In addition, the conditions of Theorem 3.3 are also easy to check Acknowledgments This work is sponsored by the ... be the number if it exists with the property that given ε > there is a neighborhood U of t with y ρ t −y s − y∇ t ρ t − s
... where b(i) is the number of times the integer i occurs in the sequence T Note that the sum of all b(i), ≤ i ≤ n, is equal to l, the length of T A simple proof fortheexistenceof exponentially ... uR , n + 2, 0 is the transition sequence of an (n + 2)-bit Gray code In the proof of Theorem 3.1 below, the sequence j0 , j1 , , jl−1 , will be denoted by T Thus, the length ofthe sequence T ... work was unnoticed for long by authors of articles in the field of ordered codes Furthermore, we remark that an extension of [4, Theorem D] which holds forthe opposite parity of l, was introduced...
... haplotypes ofthe KIAA1109/Tenr/IL2/IL21 gene region These seven haplotypes ofthe combined five SNPs ofthe block have a pooled frequency of 96% We observed a nonsignificant undertransmission ofthe ... contributions VHT carried out the molecular genetic studies VHT and EP-T carried out the design ofthe study and drafted the manuscript VHT, EP-T, BP and CP performed analysis ofthedata PM, AB, RW, PB, ... presence ofthe HLA-DRB1 shared epitope, PTPN22-1858T and TRAF1/C5 rs10818488-A variant, and no associations were detected (data not shown) One ofthe advantages of family trio data is that they...
... reside in the nucleoplasm and therefore allow forces produced within the cytoplasm to be transmitted to the nuclear periphery Evidence forthe expression and NE localization of Page of 22 plant ... epitope forthe production of rabbit polyclonal antisera to be used to study PM3 proteins in maize We selected the sequence (zms3gsp1a, LDKDKDKYLRNPC) to allow forthe detection of either ofthe ... from the sequences listed under cDNA from Table f TM, locations of transmembrane regions predicted by the online software www.ch.embnet.org/software/TMPRED_form.html[70] The multiple TMs of the...
... supported by the Centre for Medical Systems Biology (CMSB) in the framework ofthe Netherlands Genomics Initiative (NGI) Furthermore, this project was sponsored by the VIDI grant ofthe Netherlands ... high-risk to examine the impact ofthe frequency ofthe high-risk group on the relationship between the sensitivity, specificity, PPV and NPV Note that the frequency ofthe high-risk group defined ... range ofthe risk score was to 100, but the observed range was to 32 with a median of 15 risk alleles The AUC forthe risk scores was 0.62 when the OR of each included variant was 1.1, 0.86 when the...
... previous data set removed because of lack of NT-proBNP data and two patients without BNP data in the prior analysis added, leaving the same number of patients forthe present analysis In brief, the ... the study, procured study funds, performed data analysis, and drafted the manuscript AM collected data, performed data analysis, and drafted the manuscript RT conceived the study, collected data, ... predictors of death in the ICU, NT-proBNP was superior to BNP and Figure the ICU Concentrations of NT-proBNP as a function of survival versus death in the ICU The line refers to the median, whereas the...
... (Figure 3D) and genetic testing (data not shown) was performed on the mother ofthe patient and revealed that she was not a carrier ofthe disease-causing mutation, and therefore, the patient had a ... half (50%) of male XLA patients not have family history ofthe disease, and therefore, either have a de novo or spontaneous mutation (~15-20% of patients) or the mother is a carrier ofthe mutation ... it activates the catalytic core ofthe NADPH oxidase Page of 18 formed by the gp91phox and p22phox proteins The most common form of CGD is X-linked accounting for approximately 70% of cases, due...
... paper we consider theexistence and uniqueness ofthe periodic solution to the periodic boundary value problem (1.6) and (1.7), and the asymptotic behavior ofthe solution to the initial boundary ... boundary value problems, they are not the solutions ofthe problems However, for a pair of quasi-solutions hðt; xÞ and hðt; xÞ, the sector hhðt; xÞ; hðt; xÞi is an attractor ofthe associated initial ... a are the constant coupled upper and lower solutions of (2.5) and (2.6) According to the bootstrap technique developed in [4] and theexistence theorem of quasi-solutions given in [3], Theorem...
... as the loss ofthe mother often means loss ofthe direct carer, while the loss ofthe father puts the household in a difficult financial situation HIV/AIDS stands out as a cause of orphanhood, ... talk to them, teach them Some of them need to be taught That’s the other part Most of them come from the farms and we teach them at the workshops To have workshops maybe twice a month with them ... area, the vastness ofthe area For instance, for me to move from here in Koffiefontein to Smithfield the other sub office it’s a two hours drive, and if you drive for two hours within the same...
... Most ofthe folds are assigned to one ofthe five structural classes on the basis ofthe secondary structures of which they composed: (1) all alpha (for proteins whose structure is essentially formed ... usually classified individually The protein entries in the December 1994 ofthe Brookhaven Protein Databank (PDB) contain 3179 domains Many of these become forms ofthe same protein whose differences ... entered by the user, matches from both the text ofthe scop database and the headers of Brookhaven Protein Databank structure files To provide easy and broad access, we have made the scop database...
... forthe deleted atoms [13] Another point is that one should, in principle, always check whether the mutants not affect the 3D structure ofthe free components themselves, i.e whether or not the ... assessment of which residues ofthe labeled molecule are perturbed by the formation ofthe complex One then repeats this procedure with the second molecule labeled Under the assumption that the perturbed ... depends on the kind ofdata used (e.g the level of detail and the amount of inherent ambiguity) and the sampling method ‘Geometric’ methods might limit the number of orientations selected for docking...
... digest the matrix At the end-point ofthe assay, invasive cells appear on the underside ofthe porous membrane and can be quantified Guidelines for sterility testingof biologics is addressed in the ... on the kinetic chromogenic LAL-test that is based on the cleavage of a synthetic substrate by an enzyme produced in the reaction ofthe lysate in the presence of endotoxin The system consists of ... of blood and the ATMP, the product possesses no antimicrobial activity under the conditions ofthe test, and the sterility may be then carried out without further modification Data Analysis For...
... destruction ofthe ligaments, capsules and soft tissue Soft tissue was only removed from the upper half ofthe cranial vertebral body and the lower half ofthe caudal vertebral body The upper and ... wall ofthe annulus fibrosus Ideally, the suture penetrates the annulus close to the vertebral endplate The sutures are then fixated by surgical knots at the outer surface ofthe annulus Page of ... inner wall ofthe annulus fibrosus The sutures were then fixated by surgical knots at the outer surface ofthe annulus Mechanical Loading Simulator To assess the functional behavior ofthe spinal...
... Suppose that for each x Î X kp(y, Ty) ≤ ϕ(p(x, y))p(x, Ty) for all y ∈ Tx (3:9) Then F (T) = ∅ Proof Since k ≥ 2, (3.9) implies (3.1) Therefore, the conclusion follows from Theorem 3.1 The following ... 100-2115-M-017-001 ofthe National Science Council ofthe Republic of China Author details Department of Mathematics, Honghe University, Yunnan 661100, China 2Department of Mathematics, National ... contradiction Therefore v ∈ F (T) The proof is completed Here, we give a simple example illustrating Theorem 3.1 Example 3.1 Let X = [0,1] with the metric d(x,y) = |x – y| for x,y Î X Then, (X,d)...
... further assume that the maximum value of R-D slopes for any given packet is therefore an approximation forthe importance of that packet to the reconstruction ofthe video The coding units in the ... transform (2D-DWT) is then performed in each temporal subband to decompose the frames spatially The solid line shows thedata paths ofthe texture data, and the dashed line indicates motion information ... or user datagram protocol (UDP) as the underlying transport control protocol The proposed system is based on the best-effort delivery service in the form of UDP (the size ofthe UDP datagram...
... and t ∈ Ìk , then the delta derivative of f at the point t is defined to be the number f Δ t provided it exists with the property that, for each ε > 0, there is a neighborhood U of t such that ... has A s for all s ∈ τ, t Ì ⇒ A t Then A t is true for all t ∈ τ, ∞ Ì Remark 1.6 For t ∈ −∞, τ Ì, we replace σ t with ρ t and ρ t with σ t , substitute < for >, then the dual version ofthe above ... xΔ σ t Therefore, A σ t is true < L2 holds For each t ∈ a, ρ b Ì, with σ t t, and A t holds, then there is a neighborhood U of t such that A s holds for all s ∈ U, s > t by virtue ofthe continuity...
... between the zero and at infinity for f to establish theexistenceof periodic solutions of 1.2 Under the superlinear conditions 1.5 , there is no twist condition for f, which brings difficulty to the ... ones to the problem of finding periodic solutions for a related system of ordinary differential equations Then variational method was applied to study the related systems and theexistenceof periodic ... ψ x ,y ν f t, x t , y t dt 2.21 Our aim is to reduce theexistenceof periodic solutions of 2.12 to theexistenceof critical points of φ For this we introduce a shift operator Γ : H → H defined...