... differences between healthy and cancerous cells (Figure 1.1) These include insensitivity to anti-growth signals, tissue invasion and metastasis, limitless replicative potential, sustained angiogenesis, ... autophagosomes These autophagsomes then fuse with lysosomes to form autolysosomes, where the contents are degraded by hydrolases in lysosomes An overview of macroautophagy process is shown in 17 Figure ... vacuoles, and accumulation of senescence-associated 22 heterochromatin foci (SAHF) and senescence-associated β-galactosidase (13, 57) Senescence is controlled by tumor suppressor genes, in particular...
Ngày tải lên: 11/09/2015, 10:02
... isotope discrimination analysis was recently used to determine the levels and distribution of roots of weedsuppressive rice and barnyardgrass in soil (Gealy and Fischer 2010) Barnyardgrass is ... fractions and M and Ms are the respective masses of the total sample and soil component (g) in the sample mixture; f1 and f2 are the respective C fractions and M1 and M2 are the respective masses of ... presented as Equation 14c.12 in Supplemental Appendix 1C Results and Discussion 13 d C Levels in Roots and Shoots of Rice and Weeds: Pot Study The d13C levels in roots of the tropical C4 grass weeds were...
Ngày tải lên: 04/09/2015, 07:24
Information Technology for Managers - Explore the Facebook''s service and its successfull
... users in contrast to users of other sites such as MySpace Within this virtual community lie thousands of other communities built by users, band groups, advertisers, etc 2.2 How Facebook s Business ... Ads that social context highlights a user s connections with a brand or business Businesses can also create Facebook Pages to engage with interested customers and simulate an ongoing dialog with ... CHAPTER 5: SET UP THIS KIND BUSINESS IN VIETNAM 5.1 The Key successful factors to create a social site: The keys successful factors come from perspectives Business Perspective: - Being the first mover;...
Ngày tải lên: 04/03/2014, 20:37
Women’s Employment and Its Relation to Children’s Health and Schooling in Developing Countries: Conceptual Links, Empirical Evidence, and Policies pptx
... always shows a positive association with the level of household resources (Behrman and Knowles 1999) There is some evidence as well that the schooling impacts of additional household resources are ... intrahousehold bargaining and differential preferences of wives and husbands See Glick and Sahn (2000) for discussion 16 siblings or more adolescent and adult males in the household spend more ... This last result is consistent with Ilahi s (1999) analysis of adult wages and children s time that exploits the panel nature (repeated observations on the same individuals) of the same Peru LSMS...
Ngày tải lên: 14/03/2014, 09:20
Báo cáo khoa học: Ubiquitination of E3 ubiquitin ligase TRIM5a and its potential role pdf
... mediated by its RING-finger domain TRIM5a possesses a RING-consensus sequence (Cys-X2-Cys-X9–39-Cys-X1–3-His-X2–3-Cys-X2-Cys-X4–48Cys-X2-Cys) between amino acids 15 and 58 [3,17] (Fig 3A) This sequence ... assay to test this possibility In the assay, maltose-binding protein (MBP)-fused TRIM5a was expressed in bacteria and purified using amylose resin beads MBP–TRIM5a immobilized on the beads was ... ligases that are endogenously expressed in 1544 TRIM5a functions as an E3 ubiquitin ligase, because it ubiquitinates itself both in vitro (Figs and 3) and in vivo (Fig 4), as does Ro52 [7] Because...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo hóa học: " On Minkowski’s inequality and its application" doc
... f(x) + g(x) is constant or 1/p = (1 /s + 1/t)/2 On the other hand, in view of Minkowski s inequality for the cases of < s
Ngày tải lên: 20/06/2014, 22:20
Báo cáo hóa học: " Extension of Hu Ke’s inequality and its applications Jing-Feng Tian" pptx
... (x)e(x)dx (4) 2p E The purpose of this work is to give extensions of inequalities (3) and (4) and establish their corresponding reversed versions Moreover, the obtained results will be applied to improve ... inequality [31] and Beckenbach-type inequality that is due to Wang [32] The rest of this paper is organized as follows In Section 2, we present extensions of (3) and (4) and establish their corresponding ... inequality is one of the most important inequalities in analysis This classical inequality has been widely studied by many authors, and it has motivated a large number of research papers involving...
Ngày tải lên: 20/06/2014, 22:20
Báo cáo khoa học: "Capsular polysaccharide typing of domestic mastitis-causing Staphylococcus aureus strains and its potential exploration of bovine mastitis vaccine developmen" docx
... weak positive Transmission electron microscopy (TEM) Using transmission electron microscopy, S aureus strains were examined by the methods described previously [32] with a little modifications Columbia ... Characterization of MAb was described elsewhere [9, 10] Among 107 S aureus strains, serotype 336 was the most prevalent (50 isolates), followed by serotype (13 isolates) and serotype (13 isolates) (Table 4) ... to epithelial cell surfaces and tissue matrix [35] In a recent study, the strains freshly isolated from bovine mastitis often possess a high surface hydrophobicity, as measured by the tendency...
Ngày tải lên: 07/08/2014, 14:23
Novel dexamethasone-HPMA copolymer conjugate and its potential application in treatment of rheumatoid arthritis pdf
... cut with a low-speed saw using diamond-wafering blades The sections were mounted on plastic slides and ground to approximately 50 μm in thickness, and the surface was stained using a Giemsa stain ... plastic sections [31] The ankle joints were assessed for the presence of inflammation and tissue damage The extent of osteoclastic eroded cancellous bone surface was measured in the calcaneus using ... 5c) were populated with large osteoclasts resorbing bone as indicated by the presence of cells in resorption pits on the bone surfaces Fewer osteoclasts and less active resorption Page of (page...
Ngày tải lên: 09/08/2014, 10:20
báo cáo khoa học: "Takayasu’s arteritis presenting with temporary loss of vision in a 23-year-old woman with beta thalassemia trait: a case report" pptx
... Behçet s disease); however these disorders were ruled out because they are not associated with large vessel stenosis as seen in TA Large vessel vasculitis was ruled out because it is associated with ... tissue matrix disorders (Marfan and Ehler-Danlos syndromes), infectious large vessel aneurysm (mycobacterial, syphilitic, or fungal) and autoimmune diseases (systemic lupus, Cogan syndrome and ... prognosis in severe disease Initial results show promising outcomes and higher chances of therapeutic success may be attained by newer drugs like rapamycin (sirolimus) and everolimus These drugs...
Ngày tải lên: 10/08/2014, 23:20
Báo cáo y học: "F-18-fluorodeoxyglucose positron emission tomography-computed tomography for the diagnosis of Takayasu''''s arteritis in stroke: a case report" pptx
... Journal of Medical Case Reports 2008, 2:239 distinctive phases: a prepulseless (inflammatory or systemic) phase and a pulseless phase Clinical disease preceding the pulseless phase of TA will not ... Cerebrospinal fluid protein level (94 mg/dl) was increased without intrathecal synthesis of immunoglobulins For suspected arteritis and to detect systemic inflammatory disease, whole body scans in ... positron emission tomography in diagnosis and follow-up of patients with large vessel vasculitides Clin Exp Rheumatol 2004, 22(6 Suppl 36) :S2 1-26 Kissin EY, Merkel PA: Diagnostic imaging in Takayasu...
Ngày tải lên: 11/08/2014, 21:22
Báo cáo y học: " Takayasu''''s arteritis associated with Crohn''''s disease: a case report" pot
... clavicular bruits were detected With the diagnosis of Takayasu' s arteritis, in association with Crohn 's disease, oral prednisolone (30 mg/day) was started plus continuation of her previous medication, ... ML: Association between Takayasu' s arteritis and Crohn 's disease in two young women: case report J Mal Vasc 1999, 24:373-6 Hunder GG: Clinical features and diagnosis of Takayasu arteritis [http://www.uptodate.com/home/index.html] ... genetic link has been reported and further studies on these associations are recommended [2] Granulomas and granulomatous vasculitis are seen in both CD and TA Granulomatous vasculitis shows a common...
Ngày tải lên: 11/08/2014, 23:21
Báo cáo y học: "New role for Agrin in T cells and its potential importance in immune system regulation" ppsx
... Chromosome Homo sapiens Yes Pan troglodytes Yes Macaca mulatta Yes Bos Taurus Yes 16 Canis lupus familiaris Yes Mus musculus Yes Rattus norvegicus Yes No II Eutheria Other Caenorabditis elegans Gallus ... Agrin with functions characteristic of B/z+ Agrin [25] This is an important observation because most tissues express B/z- Agrin A subsequent publication, using specific anti-sense constructs to ... mouse lines and in vivo models A key observation from the studies discussed above is that elevated Agrin expression and its posttranslational modification is a characteristic of activated T cells...
Ngày tải lên: 12/08/2014, 12:20
Đồ án tiếng anh AN ENGLISHVIETNAMESE CROSSCULTURAL COMMUNICATION STUDY ON USING ADDRESSING FORM AND ITS POTENTIAL CULTURE SHOCK
... homestay parents An overseas student has to show his/her respect to his/her homstay parents Thus, s/ he can use titles (Mr or Mrs/Ms) and last names But this way of addressing express a distance ... younger) sister s son wife s sibling s son nephew Cháu trai husband s sibling s son 32 brother s daughter sister s daughter wife s sibling s daughter niece Cháu gái husband s sibling s daughter ... kinship word to address him/her It seems easy to address mother s older sisters/brothers and father s older sisters/brothers since they are addressed the same as “bác” Max has to call them the same...
Ngày tải lên: 08/11/2014, 23:10
Protein s nitrosylation and its relevance to redox control of cell signaling
... various redox signals into an effective second messenger system It is likened to phosphorylation/dephosphrylation process mediated by kinases and phosphatases since the process of S- nitrosylation and ... and neutrophils in the process called respiratory burst This persistent overproduction of ROS/RNS cause DNA lesions such as single strand break, double strand break and oxidized bases (eg 8-oxo-dg) ... Trx is reduced by the seleno-flavoprotein Trx reductase (TrxR) using NADPH as a reducing substrate Of the two systems, GSNOR system is specific to S- nitrosylated proteins whereas Trx system is involved...
Ngày tải lên: 09/09/2015, 17:56
A study on bottom spray granulation and its potential applications
... regression equation Yfines response (fines) in response surface equation Ylumps response (lumps) in response surface equation Yvel response (air velocity within the partition column) in regression ... regression equation Xmoisture linear term (binder spray rate) in regression equation Y response Yasp response (aspect ratio) in response surface equation YASA response (amount of acetylsalicylic ... 14 Pearson s coefficients of correlated variables 140 Table 15 Size and dissolution properties of PG and TG granules used to prepare tablets for disintegration and dissolution studies ...
Ngày tải lên: 11/09/2015, 09:15
Polo like kinase 1 in hepatocellular carcinoma clinical significance and its potential as a therapeutic target
... Kinase Gene Sequences Analysis PLK1 genes from selected patients were sequenced using VariantSEQr resequencing system, (Resequencing set ID version: RSS000014009_02, Applied Biosystems) and analyzed ... data was expressed as mean ± standard error of the means (SEM) unless otherwise specified 12 RESULTS Selected Genes Expressions in Human Hepatocellular Carcinoma Patients Gene expression levels of ... expression Please refer to Table A1 under Appendix for patient ID Statistical Analysis Statistical analysis was carried out using Microsoft Excel or SPSS p value of less than 0.05 was deemed significant...
Ngày tải lên: 16/10/2015, 15:38
báo cáo khoa học: "Analysis of the expression pattern of the BCL11B gene and its relatives in patients with T-cell acute lymphoblastic leukemia" doc
... intrinsic and death receptor-mediated apoptosis pathways [18] Secreted phosphoprotein (SPP1) is also known as OPN and its abnormal activation can stimulate tumor growth, invasion, angiogenesis, and ... levels in different samples, while the Mann-Whitney U test and Spearman s rank correlation analyses were used for non-normally distributed data using the SPSS 13.0 statistical software Differences ... to suppress the activity of caspase-8; thus, as a kind of protection mechanism, the TNFSF10 gene of some Page of patients is highly expressed, promoting caspase-8 activity in response to this...
Ngày tải lên: 10/08/2014, 22:21
Facile synthesis of leaf like Cu(OH)2 and its conversion into cuo with nanopores
... nm Conclusions In summary, a sophisticated production of Cu(OH)2 microleaves has been successfully synthesized with micelles acting as soft templates The addition of Span80 molecules is believed ... nanostructures with various morphologies, such as nanowires[21−23], nanoribbons[23], nanosheets[24], nanoellipsoids[24,25], pricky microspheres[26], flowerlike[27,28], and dendritic assemblies[29], ... component was Cu(OH)2 A conspicuous feature of the Cu(OH)2 crystals is their broadness, which indicates the small size of the Cu(OH)2 crystals Fig.4(b−f) presents the XRD patterns of the products prepared...
Ngày tải lên: 02/09/2015, 13:16
Báo cáo y học: "Epidemiological manifestations of hepatitis C virus genotypes and its association with potential risk factors among Libyan patients" pps
... transmission such as blood transfusion, surgery and dental procedures This is an agreement with studies from Pakistan and Hungry where the majority of cases of genotypes and have history of hospitalization ... modes of transmission The genotypes reported in this study were isolated from all the patients with the risk factors stated Such, relationship between HCV genotypes and risk factors was statistically ... analyzed using SPSS version 11.5 to identify the distribution of different genotypes and its association with gender, age, year of diagnosis and risk factors Results Prevalence of HCV genotypes among...
Ngày tải lên: 12/08/2014, 02:20