... purpose of this paper is two-fold First, we present current summary pregnancy risk information for selectedmedications or classes ofmedicationsusedtotreat RA This information is intended to describe ... of the safety of a single drug but rather to the evaluation of the wide variety ofmedications that are usedtotreat a specific disease during pregnancy Second, the objectives of the study are ... exposure Relative to the use of antimalarial drugs for the treatment of rheumatic diseases, additional studies have been required because of the higher doses used for treatment of those disorders...
... that used a cross-section of serum referred to a rheumatology laboratory found moderate to good agreement between ANA-IIF and anti-DNA results with two commercial EIA kits [6] Analysis of the ... required to achieve the goal of improving the quality of patient care through the use of autoantibody testing and analysis The matrix of manufacturing and application of autoantibody diagnostic kits ... operate under a high level of security, of scrutiny and of standardization, and under good laboratory practices and quality control Many of these companies subscribe to and offer postmarketing quality...
... number of both α- and β-adrenergic receptors This is either related to sepsis itself or to the use of vasopressors for long periods of time Corticosteroids may help with the resensitization of these ... have, given the frequency of relative adrenal insufficiency in this population and the lack of a downside to the use of lower doses of corticosteroids, the routine use of corticosteroids is probably ... resensitization of these receptors, leading to haemodynamic improvement – decreasing catecholamine requirements, reversal of shock and perhaps even reversal of organ system failure All of these effects may...
... respect to age, gender, and the amount ingested To investigate the strength of the association between a variety of study factors and arrhythmia, the odds ratio (OR) of exposure to the study factor ... measured from the earliest QRS deflection to the end of the T-wave, defined as the point of return of the T wave to the isoelectric baseline If the end of the T wave could not be determined reliably, ... usefulness of QT dispersion as a predictor of arrhythmias in these overdoses The cases recorded in the Department of Clinical Toxicology database, Newcastle include all patients who presented to hospital...
... The primary goal of our survey was to compare the availability of each resource to implement the SSC guidelines, the percentage of implementable guidelines, and the possibility to implement the ... not even all respondents of high-income countries reported to have resources available to implement the SSC guidelines was unexpected However, this was due to the lack ofselected resources (for ... (59.6 to 84.6) 100 (100 to 100)
... in the aqueous phase of supernatant (Wfree 5-FU) by the total amount usedof 5-FU The %DL was obtained by dividing that difference by the total weight of SLNs according to the following formulae: ... dissolved in 10 ml of dichloromethane Certain amounts of 5-FU was dissolved in ml of 2.5% w/v lactose monohydrate in distilled water to avoid particle aggregation after freeze drying of SLNs Both lipid ... low cost, ease of scale-up, and manufacturing [14,15] In contrast to emulsions and liposomes, the particle matrix of SLNs is composed of solid lipids The majority of lipids commonly used are triglyceride...
... sequence of eugenin (for sequence, see Table 1) Synthesis of eugenin Eugenin was synthesized to confirm the structure of the compound, and to provide sufficient material to allow biological testing to ... and caerulein bind to CCK receptors [42] There are two types of CCK receptor, CCK1 and CCK2, differing in anatomical locations and actions [43] The sequences of the CCK receptors are known [44] ... may act to stimulate the immune cells in the skin As well as stimulation of the proliferation of lymphocytes, activation of CCK receptors stimulate production of interleukins and secretion of immunoglobulins...
... of Air Force contracting and Identified different sources of Air Force contracting and other data to “piece together” total spend other data to “piece together” total spend Identified indicators ... standardization Lack of economies of scale or scope or tradeoffs among them Lack of economies of scale or scope or tradeoffs among them Separate pots of funding Separate pots of funding Payoffs from competition ... benchmarking tools The application of analytical and benchmarking tools that link these analyses to help identify key indicators that link these analyses to help identify key indicators of prospective...
... International Style, while to others it still holds onto characteristics of Streamline Moderne In can be considered to be in the International Style primarily because of its lack of decoration and regularity ... International Style that were becoming very popular, and one of these was the furniture A principle of the Bauhaus was to cater to the development of contemporary housing The Bauhaus designers were infatuated ... leather quilted cushions, sitting atop a double X shaped frame made of steel It became the symbol for the elegance of the avante-garde lifestyle Today, this piece of furniture is still as captivating...
... address the problem of health professionals’ lack of training in health educational methods “The role of the facilitator often requires the learning of new skills therefore the details of the training ... quality of life can be determined 1.4.5 Quality of life Since 1947, indicators for quality of life have been used as a way of investigating more subjective goals for clinical therapies These indicators ... setting and that the professionals must be trained and qualified to use these concepts so as to be able to work together to complete their task The challenges in this area are thus: To create coherence...
... need to develop and validate a specific instrument to measure the attitudes of medical students towards patients with physical disability The instrument has to cover aspects relevant to today’s ... relating to attitude toward physically disabled individuals Additional file 2: Characteristics of validated survey instruments to measure attitudes of healthcare students and professionals towards ... and professionals towards patients with physical disability List of non-validated survey instruments that were usedto measure attitudes of healthcare students and professionals towards patients...
... performed in 33.3% of patients with a Karnofsky score of 50–70 and in 43.8% of patients with modified Tokuhashi score of 2–4 Sundaresan et al stated that effective surgical treatment of neoplastic ... estimation of early death, which can be usedto predict of life expectancy for selecting surgical procedure of spinal metastases after operation [2,3,15] Radiotherapy, alone, can be usedtotreat ... extension of the tumor into consideration The goal of the surgery should be to delay or eliminate local recurrence to prevent neurological deficits Proper use of both modified Tokuhashi and Karnofsky...
... drug used in the generation of chemoresistance A better understanding of these mechanisms may lead to the development of novel strategies to circumvent the problem of drug resistance Background ... independently selected for resistance to cisplatin, doxorubicin or paclitaxel, and we use gene expression profiling to identify genes and pathways that may be important to the development of drug resistance ... AN, Tonda M, Sun S, Rackoff W: Long-term survival advantage for women treated with pegylated liposomal doxorubicin compared with topotecan in a phase randomized study of recurrent and refractory...
... The expansion of the generating functions can be done by power series expansion PSE It is very important to note that PSE scheme leads to approximations in the form of polynomials of degree p, ... 15 : model of neuron, bioelectrode model, model of respiratory mechanics, compartmental model of pharmacokinetics, and so forth, In this section we mention and describe only three of them, namely ... have the units of sec q to maintain a consistent set of units for the magnetization Numerical solution of Bloch equations 3.7 was obtained by using the relationship 2.22 , which leads to solution...
... significant relationships of average richness of diatoms to environmental variables. 31 Figure 4.2 Statistically significant relationship of average abundance of diatoms to Secchi depth. 32 Figure ... significant relationships of average ATSPT of diatoms to environmental variables. 33 Figure 5.1 Statistically significant relationships of average richness of zooplankton to environmental variables. ... significant relationships of average abundance of zooplankton to environmental variables. 38 Figure 5.3 Statistically significant relationships of ATSPT of zooplankton to environmental variables....
... g/dL)] and number of extranodal sites with number of nodal sites (more than four) Low risk (zero or one factor) was assigned to 36% of patients, intermediate risk (two factors) to 37%, and poor ... the presence or absence of five adverse prognostic factors and may have none or all five of these adverse prognostic factors Figure 105-4 shows the prognostic significance of this score in 1300 ... 1300 patients with all types of non-Hodgkin's lymphoma With the addition of rituximab to CHOP, treatment outcomes have improved and the original IPI has lost some of its discrimination power A...
... the opposite of meaning The concrete form of antonymy is called “antonym” (opposite) The word pairs of antonym can be divided into several types: •Implicitly gradable pairs (graded antonym) •Complementary ... Semantics is the study of meaning that is usedto understand human expression through language Semantics is perhaps the most difficult part of the grammar of a language to learn What is “semantics”? ... pairs Another characteristic of certain pairs of gradable antonyms is that one is marked and the other is unmarked The unmarked member is the one used in questions of degree We ask: ordinarily,...
... presence of brown sawdust on the bark or at the foot of the tree (10 of 11 officers) Resin exudates were also considered by of the 11 officers as the most important symptom for the identification of ... tree The yellowing of the crown and the bark falling off in patches were listed by 80% of the officers as very important symptoms for the identification of attacks Section two of the questionnaire ... etc.) Locality Name of the place of felling Compartment Compartment and plot number Species Tree species Date Date of the marking of the trees to be felled Operation Type of felling operation...
... responder, and presentation of data in this way allowed different definitions of responder to be applied The number needed totreat (NNT) to produce each level of response for each etoricoxib dose compared ... time to reconsider the place of drug therapies in arthritis [1] Page of (page number not for citation purposes) pain relief Number needed totreat for each dose of etoricoxib at each level of pain ... responses to drugs [7], leading to limited response rates for any particular drug Other workers have attempted to calculate numbers needed totreat for osteoarthritis trials For example, NNTs of to...