... considered unimportant for binding: K2 12 ( 62) A; E 213 (62a)A; D194(63)A; I 216 (65)A; Y 218 (67)A; N 227 (76)A; Q 229 (78)A; E235(84)A; K264 (11 0a)A; E265 (11 0b)A; R267 (11 0d)A; H4 02( 2 41) A; K404 (24 3)A , Signicantly ... ã 10 4 (s )1) 0.47 k1 ã 10 )5 (M )1 s )1) LRP -1 A binding k )1 ã 10 4 (s )1) Kd (nM) 0.054 7.05 (10 ) 6.53 (10 ) 6.73 (10 ) 3. 12 (9) 4 .20 1. 37 Kd (nM) k1 ã 10 )5 (M )1 s )1) SorLA binding k )1 ã 10 4 (s )1) ... 2. 30 0.74 1. 43 2. 54 3.86 18 .9 1. 12 0.60 3.63 0.368 1. 96 0.56 1. 17 0.83 Wild-type R178(35)A-R179 (36)A-R1 81( 37a)A Wild-type R178(35)A-R179 (36)A-R1 81( 37a)A K71A-R78AY81A-K82A K71A-R78AY81A-K82A...
Ngày tải lên: 30/03/2014, 10:20
... gts1D pACGTS1[N-C]/gts1D pACGTS1[DKN]/gts1D pACGTS1[C53Y]/gts1D tdh1D tdh2D tdh3D pACTDH1/tdh1D pACTDH1pr.TDH2/tdh1D pACTDH1pr.TDH3/tdh1D 5.03 5. 12 5 .10 5.08 5.03 5. 01 4.58 3. 32 4.95 3.40 2. 45 ± ± ... ± ± ± ± ± 0.08 0 .11 0 .18 0 .23 0 .15 0 .13 0 .20 0 .27 0 .26 0.40 0.35 (8)c (5) (3) (3) (3) (3) (3) (2) (3) (2) (2) Duration (h) Amplitude (%)b 1 32 ± 4.4 (No or short oscillations) 11 7 ± 7.8 (No oscillations) ... [22 ,25 ] To transform gts1D(W303) with GTS1, GTS1[DKN] and GTS1[C53Y], the constructs were inserted into the vector pYX 222 at the multicloning site These transformants were named pYXGTS1/gts1D(W303),...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: " Construction of doxycyline-dependent mini-HIV-1 variants for the development of a virotherapy against leukemias" pps
... Retrovirology 20 06, 3:64 http://www.retrovirology.com/content/3 /1/ 64 + dox 10 000 10 00 CA-p24 (ng/mL) + dox 10 000 10 00 10 0 10 0 10 10 1 0 10 12 14 16 18 10 000 10 12 14 16 18 16 18 10 000 - dox - dox 10 00 ... mutant tumors with ONYX- Page 11 of 12 (page number not for citation purposes) Retrovirology 20 06, 3:64 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 015 , an E1B-55kD gene-deleted adenovirus, ... PE 10 4 10 3 rtTAΔ6A 1 02 10 10 1 1 02 10 3 10 4 CD8 FITC rtTAΔ6B SupT1 + PBMC CD4 PE 10 4 10 3 1 02 rtTAΔ6A no dox 10 1 10 1 1 02 10 3 10 4 CD8 FITC Figure Selective SupT1 killing in SupT1/PBMC co-cultures...
Ngày tải lên: 13/08/2014, 09:20
Oxford collocations dictionary for students of english chương 2 1
... of free trade I chief,leading, main, principal • PREP -for He is one of the leading adoocates for a more modern style of worship -of an advocate of pacifism lawyer • ADJ defence q Note at PROFESSIONAL ... under the age of lB with - A lot of wines improve with age , -of He left school at the age of I S • PHRASES the age of consent The general age of consent for sexual activity is 16 sb's own age ... in alignment with theframe beforeyou start work on it out of- Afew of + ALIGNMENT • PREP the tiles were clearly out of alignment political support • ADJ close I military, political establish, form...
Ngày tải lên: 19/08/2013, 09:53
Tài liệu Oxford Collocations Dictionary for students of English_ Chương 2.1 ppt
... of free trade I chief,leading, main, principal • PREP -for He is one of the leading adoocates for a more modern style of worship -of an advocate of pacifism lawyer • ADJ defence q Note at PROFESSIONAL ... under the age of lB with - A lot of wines improve with age , -of He left school at the age of I S • PHRASES the age of consent The general age of consent for sexual activity is 16 sb's own age ... in alignment with theframe beforeyou start work on it out of- Afew of + ALIGNMENT • PREP the tiles were clearly out of alignment political support • ADJ close I military, political establish, form...
Ngày tải lên: 10/12/2013, 13:15
báo cáo khoa học: " FCR (Fludarabine, Cyclophosphamide, Rituximab) regimen followed by 90yttrium ibritumomab tiuxetan consolidation for the treatment of relapsed grades 1 and 2 follicular lymphoma: a report of 9 cases" pot
... (Table 2) Restage before RIT: CT, PET, BMB Zevalin® FCR -28 CYCLES 11 .1- 14.8 MBq/Kg CR/CRu or PR F: 25 mg/m2 i.v days 1- 3 C: 1gr/m2 i.v day R: 375mg/m2 i.v day Figure Treatment schema Restage 12 ... et al Journal of Experimental & Clinical Cancer Research 20 11 , 30 :16 http://www.jeccr.com/content/30 /1/ 16 Received: 30 September 20 10 Accepted: February 20 11 Published: February 20 11 References ... Y-RIT 14 .8 MBq/Kg - 11 MBq/Kg, if the platelet number was between 10 0 × 10 9/L and 14 9 × 10 9/ L, not to exceed a total of 1. 184 MBq administered as a slow i.v push over 10 minutes (Figure 1) Assessments...
Ngày tải lên: 10/08/2014, 10:21
Báo cáo y học: " Induction of the HIV-1 Tat co-factor cyclin T1 during monocyte differentiation is required for the regulated expression of a large portion of cellular mRNAs" pptx
... activity of CDK9/cyclin T complexes Nature 20 01, 414 (68 61) : 322 - 325 Page 15 of 16 (page number not for citation purposes) Retrovirology 20 06, 3: 32 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 ... polymerase II Mol Cell Biol 20 00, 20 (8) :26 29 -26 34 Liu H, Herrmann CH: Differential localization and expression of the Cdk9 42k and 55k isoforms J Cell Physiol 20 05, 20 3 (1) :25 1 -26 0 Michels AA, Nguyen ... 0.5% of genes assayed (13 1 of 18 ,953) were repressed >2- fold by shRNA-CycT1, while 0.7% of genes (87 of 18 ,953) were induced >2- fold by shRNA-CycT1 (Table 1) We next examined the number of genes...
Ngày tải lên: 13/08/2014, 09:20
the american practical navigator table 34 conversion table for millibars, inches of mercu~1
Ngày tải lên: 09/05/2016, 09:04
Longman Dictionarry of Common Errors_ part 2.1
... are clamouring for stricter laws that will help to protect wives and children.' x r At the end of World War 11 there was a claim for a 'United Europe' At the end of World War 11 there was a demand/clamour ... costume = (1) (countable) a set of clothes worn during a performance by an actor, clown, etc: 'She used to work for a theatre company, designing and making costumes.' (2) (uncountable) a set of clothes ... claimed damages of 20 00 for wrongful dismissal.' X I X I The floods made a lot of damage The floods did/caused a lot of damage Most of the damage has been produced by acid rain Most of the damage...
Ngày tải lên: 22/10/2013, 15:15
LUYỆN ĐỌC TIẾNG ANH QUA TÁC PHẨM VĂN HỌC-THE ADVENTURES OF SHERLOCK HOMES -ARTHUR CONAN DOYLE -2-1
... little square of card-board hammered on to the middle of the panel with a tack Here it is, and you can read for yourself." He held up a piece of white card-board about the size of a sheet of notepaper ... your while to put yourself out of the way for the sake of a few hundred pounds.' "Now, it is a fact, gentlemen, as you may see for yourselves, that my hair is of a very full and rich tint, so ... sorry to hear you say that The fund was, of course, for the propagation and spread of the red-heads as well as for their maintenance It is exceedingly unfortunate that you should be a bachelor.'...
Ngày tải lên: 08/11/2013, 02:15
Tài liệu CAMBRIGDE INTERNATIONAL DICTIONARY OF IDIOMS_ CHƯƠNG 2.1 pdf
... from her a cold snap a coffee table book a large, expensive book with a lot of pictures, that is often kept on a table for people to look at • A glossy coffee table book of his art work will bepublished ... the clutches of a religiousfanatic C-note a C-note American, informal a piece of paper American money that is worth 10 0dollars Joe took a wad of bills out of his pocket, peeled off a c-note and ... died • (often + for) The new superstore will sound the death knell for hundreds of small independent shops • (sometimes + of) The closure of the local car factory tolled the death knell of thetown...
Ngày tải lên: 21/12/2013, 04:15
iec 60269-2-1 low-voltage fuses - supplemetary requirements for fuses for use by authorized perso
... E71I23JE0375 2EJ9E % 17 G0 327 5j509756DGEJ9:75L43DU49EJH75675@d- 511 5605:79E375675HS2H 217 9E5675371IHJ: 717 9ET f1 '1) 1&// bA,F-*7/*\7448+ d )J5E71I23JE03756J9G5HS2E0N757GE5I43E275j5h B- +- i5•
Ngày tải lên: 25/12/2013, 10:47
iec 60269-4-1 low-voltage fuses - supplementary requirements for fuse-links for the protection of
... 50 19 45 6,5 11 0 15 0 80 80 11 0 50 24 53 11 0 15 0 80 80 11 0 50 24 11 0 15 0 80 80 11 0 50 29 11 0 15 0 80 Body size h1 h2 i + 0,3 0 -0,5 M10 11 11 6,5 M10 11 11 61 6,5 M10 11 11 76 6,5 M 12 13 13 7) 1) ... 10 ,7 19 ,8 65 – 10 0 11 3,6 92, 1 95,5 72 74,6 31, 4 5 ,2 25,8 10 ,7 18 ,6 11 0 – 20 0 13 1 1 02, 4 10 8 72 73,8 38,5 6,8 25 ,8 12 , 3 21 22 5 – 400 13 1 1 02, 4 11 1 73 73,8 51 ,2 6,8 38,5 14 ,7 20 ,2 450 – 600 18 1,6 12 9 ,4 ... 92, 1 95,5 72 74,6 31, 4 5 ,2 25,8 10 ,7 18 ,6 11 0 – 20 0 13 1 1 02, 4 10 8 72 73,8 38,5 6,8 25 ,8 12 , 3 21 22 5 – 400 13 1 1 02, 4 11 1 73 73,8 51 ,2 6,8 38,5 14 ,7 20 ,2 450 – 600 18 1,6 12 9 ,4 14 7 81 73,9 63,9 10 ,1...
Ngày tải lên: 25/12/2013, 10:54
Tài liệu Báo cáo khoa học: Myristoylation of the dual-specificity phosphatase c-JUN N-terminal kinase (JNK) stimulatory phosphatase 1 is necessary for its activation of JNK signaling and apoptosis pdf
... y-CH3SOH 522 .33 586.33 OxM 408 .19 344 .19 26 8 .23 3 82. 27 439 .29 Myr-Gly Asn Gly 579 .26 465 . 21 515 .26 4 01 . 21 MH+ MH+- 846.48 636.37 700.37 Asn Lys 26 1. 16 14 7 .11 CH3SOH 7 82. 47 b3 439 .29 y2 26 1. 16 y5CH ... 522 .34 y4y2-NH3 24 4 .14 y1 14 7 .11 CH3SOH y3- 4 01 .22 CH3SOH 783.48 b4 586.33 344 .20 b1 26 8 .23 847.47 y5 579 .26 b2 3 82. 28 y4 465 . 21 b5 700.37 b5- 848.48 CH3SOH 636 .29 784.47 829 .44 10 0 m/z 20 0 from whole ... identification Rapid Commun Mass Spectrom 14 , 20 80 20 81, doi: 10 .10 02/ 10 97- 023 1 (20 0 011 15 )14 : 21 3.0.CO ;2- P [pii] Kerr JF, Wyllie AH & Currie AR (19 72) Apoptosis: a basic biological phenomenon...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines A possible strategy for the maintenance of intracellular heme level pdf
... Reduced expression of heme oxygenase -2 20 21 22 23 24 25 26 27 28 29 30 31 Y Zhang et al explants and immortalized trophoblast cells Am J Physiol Heart Circ Physiol 28 4, H853–H858 Poss KD, Thomas MJ, ... heat shock J Biol Chem 26 2, 12 8 89– 12 8 92 45 Trakshel GM & Maines MD (19 88) Detection of two heme oxygenase isoforms in the human testis Biochem Biophys Res Commun 15 4, 28 5 29 1 46 Heinemeyer T, Wingender ... HO -2 FEBS Journal 27 3 (20 06) 313 6– 314 7 ª 20 06 The Authors Journal compilation ª 20 06 FEBS Y Zhang et al Reduced expression of heme oxygenase -2 (10 0 UÆmL )1) , and streptomycin sulfate (10 0 lgÆmL )1) ...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Specific targeting of a DNA-alkylating reagent to mitochondria Synthesis and characterization of [4-((11aS)-7-methoxy-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-on-8-oxy)butyl]-triphenylphosphonium iodide doc
... P+–CH2, H -11 a and H-3), 1. 75 2. 4 (8H, m, O-CH2-CH2, P+–CH2-CH2, H -1 and H -2) p.p.m., 31 PNMR d 25 .65 p.p.m ESMS found (M+) 563 .24 69 calculated for C35H36O3N2P (M+) 563 .24 58 H (300 MHz) and 31P ( 12 1 ... pressure for h yielding as a mustard coloured solid ( 12 mg, 0. 014 mmol, 14 %) 1H NMR d 7.6–7.9 (m (16 H, P+–ArH and H -11 ), 7.46 (1H, s, H-6), 6.49 (1H, s, H-9), 4 .1 4 .2 (2H, m, Ar-O-CH2), 3. 71 (3H, ... expression (Fig 1) For the DNA alkylating reagent we chose the antibiotic (11 aS)-8hydroxy-7-methoxy -1 ,2, 3 ,11 a-tetrahydro-5H-pyrrolo [2, 1c] [1, 4]benzodiazepin-5-one; (DC- 81) [1 ,25 ] This DNAalkylating...
Ngày tải lên: 20/02/2014, 11:20
Tài liệu Báo cáo khoa học: Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat docx
... FEBS 20 02 15 16 17 18 19 20 21 22 HIV TAT-CRAC peptide Proc Natl Acad Sci USA 98, 12 6 7± 12 7 2 Hughes, J., Astriab, A., Yoo, H., Alahari, S., Liang, E., Sergueev, D., Shaw, B.R & Juliano, R.L (20 00) ... Grb2binding peptide J Biol Chem 27 2, 22 349 22 354 12 Dostmann, W.R., Taylor, M.S., Nickl, C.K., Brayden, J.E., Frank, R & Tegge, W.J (20 00) Highly speci®c, membrane-permeant peptide blockers of ... Chem 27 2, 16 010 16 017 Á 10 Vives, E., Granier, C., Prevot, P & Lebleu, B (19 97) Structure activity relationship study of the plasma membrane translocating potential of a short peptide from HIV-1...
Ngày tải lên: 21/02/2014, 03:20
Tài liệu UNIT 1. ONLINE COMMUNITIES: A NEW OPPORTUNITY LESSON 2. ONLINE COMMUNITIES FOR DEVELOPMENTNOTE ppt
... ftp://ftp.inet.co.th/pub/sea-aids/info/info 11. txt Terri Willard, T (20 01) Dating the Decision-makers: Moving from Communications to Engagement http://www.iisd.org/pdf /20 01/ networks_engagement.pdf ITrainOnline: Strategic Use of the ... http://web.idrc.ca/panasia/ev-4509 -20 1- 1-DO_TOPIC.html International Institute for Sustainable Development Strategic Intentions: Managing knowledge networks for sustainable development,http://www.iisd.org/pdf /20 01/ networks_strategic_intentions.pdf ... employment issues for 15 years She had a deep set of knowledge, which she was always expanding One of the things she had discovered for creating jobs was bamboo-based products for export Trupti...
Ngày tải lên: 22/02/2014, 01:20
Báo cáo khoa học: Suppression of NADPH oxidase 2 substantially restores glucose-induced dysfunction of pancreatic NIT-1 cells doc
... (fold of control) 11 .1 5.5 22 .2 2.5 2. 0 1. 0 0.5 0.0 33.3 0h 6h 12 h 24 h 48 h 1 D-Glucose (33.3 mmol·L ) D 0.3 * Control Glucose 0 .2 0 .1 0.0 1 .2 Relative quantification (fold of control) C ** * 1. 5 ... F & Wang X (20 03) Elimination of Mcl -1 is required for the initiation of apoptosis following ultraviolet irradiation Genes Dev 17 , 14 75 14 86 FEBS Journal 27 7 (20 10 ) 50 61 50 71 ª 20 10 The Authors ... glucose-induced insulin secretion J Biol Chem 28 0, 328 35– 328 42 FEBS Journal 27 7 (20 10 ) 50 61 50 71 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 50 71 ...
Ngày tải lên: 06/03/2014, 02:20