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synthesis of the superheavy

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Báo cáo khoa học: "Analysis and Synthesis of the Distribution of Consonants over Languages: A Complex Network Approach" pptx

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... these 21 consonants.On the other hand Regime 2 of Figure 3(a) as wellas Regime 1 of Figure 3(b) comprises of the rest of the consonants. The point marked as x in both the figures indicates the ... correspondingto the nodes in the set VLand the other corre-sponding to the nodes in the set VC.Degree distribution of the nodes in VL: Fig-ure 2 shows the degree distribution of the nodesin ... occur-rence principles of the consonants in the invento-ries of the world’s languages. The work can be fur-ther extended to identify the co-occurrence likeli-hood of the consonants in the language inventories134and...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf

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... interruption of triacylglycerol synthesis in the endoplasmic retic-ulum, apparently because of the formation of a pool of oversaturated inter-mediates, represents the key initiating event in the mechanism ... 5B). The ER is the site of synthesis of all secretory pro-teins and resident proteins of the membrane system,and any perturbation that compromises the protein-folding capacity of the organelle ... available acyl-CoAs are in excess,they are channeled towards TAG synthesis. The main findings of the present investigation were the observations that TAG synthesis in liver cellsexposed to excess...
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Tài liệu Báo cáo khóa học: Characterization of the products of the genes SNO1 and SNZ1 involved in pyridoxine synthesis in Saccharomyces cerevisiae pptx

Tài liệu Báo cáo khóa học: Characterization of the products of the genes SNO1 and SNZ1 involved in pyridoxine synthesis in Saccharomyces cerevisiae pptx

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... min, the absorbance of the supernatant was read at 363 nm. The absorbance of the reduced form of APAD (APADH) was linear over the 2–100 lMrange of glutamate with a molar extinctioncoefficient of ... complement the defect. The relationship of all of these genes remains to be clarified.Expression and purification of Sno1p and Snz1pIn light of the similarity in the amino acid sequence of Sno1p ... together in the stationary phase of yeast cells [8] and the result of two-hybrid analysis [23], they may form a complex. To assessthese possibilities, we embarked on a characterization of the...
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Tài liệu Báo cáo khoa học: Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3¢-end of virus minus-strand RNA docx

Tài liệu Báo cáo khoa học: Template requirements and binding of hepatitis C virus NS5B polymerase during in vitro RNA synthesis from the 3¢-end of virus minus-strand RNA docx

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... deletion mutants of the 3¢ terminus of the minus-strand RNA but deletionswere made on the basis of the structure of the 5¢UTR of the plus-RNA, the structure of the 3¢-end of the minus-strand ... RNA synthesis directed by the HCV NS5B. To assess whether the low level of RNA synthesis was related to the binding of these templatesto the HCV RdRp, we performed gel shift assays.Results of ... In the first step the viral replicase synthesizes a minus-strandRNA that serves as a template for the synthesis of new plus-strand RNA molecules. Initiation of RNA synthesis at the 3¢-end of the...
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Tài liệu Báo cáo Y học: The glucose-specific carrier of the Escherichia coli phosphotransferase system Synthesis of selective inhibitors and inactivation studies pptx

Tài liệu Báo cáo Y học: The glucose-specific carrier of the Escherichia coli phosphotransferase system Synthesis of selective inhibitors and inactivation studies pptx

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... + Na]+, 100%).RESULTS Synthesis of inhibitors The synthesis and characterization of compounds 1b, 1d, 1f,1g and 3b (Scheme 1) is reported for the first time, and the epoxypropyl derivative ... The key step is the use of Collinsreagent for the selective oxidation of the primary trimethyl-silyl ether of the fully silylated monosaccharide 8 to analdehyde (step ii). The resulting 2,3,4-tris-trimethylsilylatedderivative ... site. The curved shape of the plot and the KI/KSratios indicatethat the C-6 epoxide 1d, like the C-6 aldehydes of Glc andaMGlc [15], preferentially inhibits the low-affinity site of EIIGlc....
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Tài liệu Báo cáo Y học: Dinucleoside polyphosphates stimulate the primer independent synthesis of poly(A) catalyzed by yeast poly(A) polymerase ppt

Tài liệu Báo cáo Y học: Dinucleoside polyphosphates stimulate the primer independent synthesis of poly(A) catalyzed by yeast poly(A) polymerase ppt

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... activity of GpnGs as effectors of the synthesis of poly(A)Based on the above results, the effect of several diguanosinepolyphosphates on the synthesis of poly(A) was comparat-ively studied. The ... independent synthesis of poly(A)In order to understand why dinucleoside polyphosphatesactivated the primer independent synthesis of poly(A), the effect of 0.01 mMGp4GorAp4A on the synthesis of poly(A) ... confirming the adenylylation of thesecompounds and the absence of synthesis of poly(A) by the E.colipoly(A) polymerase, we did not observed adenyly-lation of guanosine, GDP or Gp4G by the yeast...
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Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx

Tài liệu Báo cáo Y học: Steady-state kinetics of the glutaminase reaction of CTP synthase from Lactococcus lactis The role of the allosteric activator GTP in coupling between glutamine hydrolysis and CTP synthesis potx

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... locks the enzyme in the active form for CTP synthesis andthereby stimulates the kcat of the reaction. Since GTP actually willactivate the uncoupled glutaminase reaction the structure of the monomer ... wassimilar to that of the overall CTP synthesis reaction. Itwas concluded that the effect of GTP was mainly toenhance the rate of chemical steps of the glutaminasereaction. The finding that the kcatvalue ... ATP-cS. On the basis of these results, ATP-cSwas chosen as a binding analog of ATP. CTP synthesis requires the presence of both the nucleotide substrates ATPand UTP. When phosphorylation of UTP...
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Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx

Tài liệu Báo cáo Y học: Phosphatidylinositol synthesis and exchange of the inositol head are catalysed by the single phosphatidylinositol synthase 1 from Arabidopsis docx

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... on the same plot of the valuesfound for de novo synthesis in the presence of 7.5 or 2.5 mMMnCl2with various amounts of EDTA, or in the presence of MnCl2only [11], as a function of the ... showing that the endogenous level of CDP-DAG is too low to allow detectable synthesis. The level of PtdIns in the membranes does not allow synthesis of detectable PtdIns by exchange of the polar ... by the exogenoussoybean PtdIns.A question that arises is the relevance of the exchange of polar head when de novo synthesis is studied. Wecalculated that with a linear rate of synthesis of...
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Báo cáo khoa học: Heterologous synthesis of cytochrome c¢ by Escherichia coli is not dependent on the System I cytochrome c biogenesis machinery ppt

Báo cáo khoa học: Heterologous synthesis of cytochrome c¢ by Escherichia coli is not dependent on the System I cytochrome c biogenesis machinery ppt

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... heterologously syn-thesized in the periplasm of E. coli JCB387 cells(Fig. 4). Judging from the staining intensity, the level of production of the PHCP protein in the presence of the pEC86 plasmid ... synthesize the PHCP and PH c552proteins,confirming that the observed difference between the two proteins in the RI242 strain is a result of the absence of the DsbD protein.PHCP was also synthesized ... the latter.Heterologous synthesis of PHCP by E. coli The E. coli System I cytochrome c biogenesis machin-ery, consisting of the Dsb and Ccm proteins, is respon-sible for the synthesis of class I cytochromes...
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Báo cáo khoa học: Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase doc

Báo cáo khoa học: Mycobacterium tuberculosis possesses a functional enzyme for the synthesis of vitamin C, L-gulono-1,4-lactone dehydrogenase doc

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... therefore involved in a wide array of crucialphysiologic processes, including: biosynthesis of colla-gen and other hydroxyproline ⁄ hydroxylysine-containingproteins ⁄ peptides; synthesis of ... characterized up to now, and the first example of a specific, vitamin C biosyntheticenzyme of bacterial origin. Further studies will benecessary to elucidate the role of the Rv1771l-gulono-1,4-lactone ... the intracellular growth of the pathogen in itshost. This could explain the absence of the l-gulono-1,4-lactone dehydrogenase reaction product in the M. tuberculosis cells grown in vitro.The...
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Báo cáo khoa học: Characterization of the tRNA and ribosome-dependent pppGpp-synthesis by recombinant stringent factor from Escherichia coli pot

Báo cáo khoa học: Characterization of the tRNA and ribosome-dependent pppGpp-synthesis by recombinant stringent factor from Escherichia coli pot

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... to all of the tRNA binding sites on the ribosome(i.e. A, P and E sites) [13,14]. As expected, the addi-tion of SF to the system resulted in pppGpp synthesis (Fig. 2). The speed of synthesis, ... template, the activity of the enzyme is similar to that in the absence of tRNA. This is not surprising because the template is needed to position tRNAs on the ribosome[26]. The activity of the poly(U)-dependent ... trans-ferase that synthesizes (p)ppGpp. Production of thisalarmone results in a down-regulation of stable RNA synthesis (rRNA and tRNA) and up-regulation of the synthesis of mRNAs encoding enzymes...
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Báo cáo khoa học: Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of b-lactam antibiotics pptx

Báo cáo khoa học: Kinetics of enzyme acylation and deacylation in the penicillin acylase-catalyzed synthesis of b-lactam antibiotics pptx

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... 7). The Vs/Vhratio is the ratio of the reaction rates of aminolysis and hydrolysis of the acyl-enzyme. The curva-ture of the plot of Vs/Vhvs. the mole fraction of D2Oindicates therefore ... muchslower than the rate of deacylation. The theoretical maxi-mum of the amplitude of the burst phase is equal to the totalenzyme concentration. When kh1¼ 5 k2, only 2% of the maximum of the amplitude ... for(Vs/Vh)maxfor the synthesis of ampicillin were obtainedfrom fitting Eqn (8) to the data. For synthesis of penicillinG, a value of 0.018 mM)1for the slope of the curve wasobtained, but due to the almost...
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Báo cáo khoa học:

Báo cáo khoa học: "A Formula Finder for the Automatic Synthesis of Translation Algorithms" docx

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... translated of the oscilla- tions of the voltage of the trigger . . . rather than by the smoother inverted construction . . . of the oscilla- tions of trigger voltage .In any event, the transla- ... Ts. 4. The Synthesis of Basic Algorithms Parallel texts need be prepared only once by the proc- ess of Fig. 3; thereafter they can be used for the de- rivation of any number of basic algorithms. ... incrementing the Xk and Yk registers. C. THE OPERATION OF THE FORMULA SYNTHESIZER The input to the final machine program shown in Fig. 4, called formula synthesizer, is the set of tally counts...
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Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

Báo cáo Y học: Guanosine diphosphate-4-keto-6-deoxy-D-mannose reductase in the pathway for the synthesis of GDP-6-deoxy-D-talose in Actinobacillus actinomycetemcomitans potx

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... content of 48.0% [43]. The GC content of the region essential for the biosynthesis of SPA in the otherserotype strains (b–e) of A. actinomycetemcomitans is alsolower than the average GC content of ... [20]. The GC contents of the genes essential for SPAbiosynthesis in A. actinomycetemcomitans SUNYaB 75are lower than the average GC content (47.8%) of the genes flanking them. The GC contents of ... FEBS 2002 The signals for H2¢ of the nucleotide moieties overlappedthat of HOD, and the H5¢¢ and H6¢¢ signals of the sugarmoieties of GDP-a-D-mannose also overlapped. The signals for the sugar...
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Báo cáo khoa học: Mutational analysis of the C-domain in nonribosomal peptide synthesis pot

Báo cáo khoa học: Mutational analysis of the C-domain in nonribosomal peptide synthesis pot

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... Amilestone in the study of peptide s ynthetases was the determination of the A-domain structure of GrsAPhe-A [8].Aspects of speci®city and binding were superimposed onother A-domains and with the help ... furtherefforts were made to track down the actual target of the inhibitors.DISCUSSION The purpose of t his work was to identify the key residuesin the C-domain a nd their potential role in the ... production by multiplying the counts in the radioac-tive assays and the area in the HPLC-assays by the ratio of counts in the thiolation assay of mutant over wild-type.Values in the elongation a ssay...
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