surface enhanced raman scattering sers for biomedical diagnostics

... of Ag thin film on glass for efficient surface- enhanced Raman scattering Langmuir 2006, 22:1626 Halvorson RA, Vikesland PJ: Surface- enhanced Raman spectroscopy (SERS) for environmental analyses ... method for preparing controllably aggregated silver particle films used as surface- enhanced Raman scattering active substrates Langmuir 2002, 18:6839 Sackmann M, Materny A: Surface enhanced Raman scattering ... chemical method for forming silver surfaces with controlled grain sizes for surface plasmon experiments Langmuir 2003, 19:6857 Hao J, Xu Z, Han M-J, Xu S, Meng X: Surface- enhanced Raman scattering...

Ngày tải lên: 21/06/2014, 04:20

... Summary Raman scattering is an important method to obtain the vibrational spectroscopic information of molecules by their inelastic scattering with photons Surface enhanced Raman scattering (SERS) ... intrinsically small in a normal Raman process, which prevents its practical applications In order to improve the Raman signal intensity, surface enhanced Raman scattering (SERS) has been widely investigated ... in Rayleigh scattering and Raman scattering [6] Figure 1.1 shows the energy-level diagram of the states involved in Rayleigh scattering and Raman scattering Raman scattering occurs when the incident...

Ngày tải lên: 09/09/2015, 08:18

... substrates for SERS measurements Rohdamine 6G was chosen as a tested analysis to investigate Raman scattering enhancement due to its well defined Raman spectrum The strong enhancement of the Raman scattering ... measured by Micro -Raman spectrophotometer of these samples are shown in Fig.8 Obtained results show that Raman signal was enhanced strongly by using the SERS substrate The SERS spectra of R6G ... left to dry on the SERS substrate R6G molecules will be absorbed onto the metal nanoparticles of the SERS substrate after some minutes SERS spectra were observed by Micro -Raman spectrophotometer...

Ngày tải lên: 24/10/2016, 15:21

... ε for the Au (Region 2) are obtained from Johnson and Christy’s previous publication (73), 117 4.4 Surface Plasmon Polariton Assisted Surface Enhanced Raman Scattering on Ultrasmooth Metal Surface ... metal surface provide sites for the coupling between a radiative field and a localized SP (LSP) mode Such a geometry is of particular importance in Surface Enhanced Raman Scattering or SERS, ... to be large enough for the SERS studies of macromolecular layers 146 Chapter Fabrication of Dielectric Spheroidal Nano-cavity Embedded Substrate for Surface Enhanced Raman Scattering In Chapter...

Ngày tải lên: 14/09/2015, 14:01

... 2.4 Enhanced Raman Scattering by Dielectric Microspheres 21 2.5 Enhanced Raman Scattering by Noble Metal: Surface Enhanced Raman Scattering (SERS) 2.5.1 21 Evidence of SERS: Excitation- and Raman- wavelength ... developed for protein layer studies Lastly, the potential of a unique surface sensitive Raman scattering phenomenon known as the Surface Enhanced Raman Scattering (SERS) in probing conformational ... Chapter General Theory of Enhanced Raman Scattering and its Experimental Verifications 2.1 General Theory of Raman Scattering 13 2.2 Enhanced Raman Scattering 13 2.2.1 Chemical Raman Enhancement 14...

Ngày tải lên: 14/09/2015, 14:02

... optical processes via coupling of the radiation field with surface plasmons of nanostructured Ag or Au These surface- enhanced RR (SERR) and surface- enhanced IR absorption (SEIRA) difference spectroscopies ... RR and the surface- enhanced Raman effect that provides the unique selectivity and sensitivity for the cofactor of the immobilized proteins is only possible with nanostructured Ag for direct excitation ... biocompatible coating materials for metal electrodes are monolayers and bilayers of lipid analogues, as they allow mimicking biological surfaces appropriate for protein binding [16] For soluble proteins,...

Ngày tải lên: 22/03/2014, 16:20

... Stokes Raman scattering is much stronger than the anti-Stokes Raman scattering Virtual anergy states Vibrational energy states Rayleigh scattering Stokes Raman scattering Anti-Stokes Raman scattering ... while the low intensity of Raman signal limits its sensitivity and imaging speed Surface enhanced Raman scattering (SERS) uses surface plasmon to significantly enhance Raman signals [9], but the ... = Raman free induction decay RP-CARS = Radially polarized CARS SERS = Surface enhanced Raman scattering SFG = Sum frequency generation SHG = Second harmonic generation SRS = Stimulated Raman scattering...

Ngày tải lên: 09/09/2015, 18:54

... the sensitivity of Raman spectroscopy is limited by the inherently very weak Raman scattering mixed with the strong fluorescence background Surface enhanced Raman scattering (SERS) detection schemes ... = Polarization CARS PMT = Photomultiplier tube RP-CARS = Radially polarized CARS SERS = Surface enhanced Raman scattering SHG = Second harmonic generation SFG = Sum frequency generation THG = ... COHERENT ANTI-STOKES RAMAN SCATTERING (CARS) AND MULTIPHOTON MICROSCOPY FOR LABEL-FREE BIOMOLECULAR IMAGING LU FAKE 2010 DEVELOPMENT OF HIGH CONTRAST COHERENT ANTI-STOKES RAMAN SCATTERING (CARS)...

Ngày tải lên: 11/09/2015, 10:00

... Ti-g-P(HEMA) surface from h of surface- initiated ATRP of HEMA, (b) the Ti-g-P(HEMA-NH2) surface, and (c) the Ti-g-P(HEMA-PE) surface 97 Figure 4-7 (a,b) C 1s core-level spectra of the Ti-g-P(HEMA) surface ... pristine or Ti-OH surface, (c, d) the Ti-Cl surface, (e, f) the Ti-g-P(MAA) surface after h of surface- initiated ATRP of MAAS and (g, h) the corresponding Ti-g-P(MAA-Silk) surface 156 Figure ... devices For normal titanium implants, the manufacturing steps usually result in an oxidized, contaminated surface, and such ‘‘native’’ surface is certainly not necessarily appropriate for all the biomedical...

Ngày tải lên: 14/09/2015, 08:37

... from both decreased grain size and possibly decreased diameter of surface pores, (ii) enhanced surface wettability due to greater surface roughness and (iii) greater numbers of grain boundaries ... the SLA (sand blasted, acid etched) surface [6] The differences in the contact angle and the surface roughness of the implant surface owing to the various surface modification techniques were ... layer caused the formation of Ti–OH groups that react with the calcium ions from the SBF and form calcium titanate, which then could act as nucleation sites for apatite crystal formation [14, 15]...

Ngày tải lên: 02/10/2015, 12:55

... (0.11±0.01 normalized relative intensity) for adipose is more than for tumors (0.09±0.01 for carcinoma and 0.07±0.02 for fibrocystic change) as well as for fibroglandular (0.08± 0.01) Table tabulates ... Evaluation of optimum scattering angle - In order to obtain the optimum scattering angle, the diffraction profiles of a test adipose sample were measured over a range of scattering angles from ... values compared with other tissues The width of the curve for tumors is noticeably greater than for adipose tissue Table gives mean values for the peak positions and widths It can be seen that the...

Ngày tải lên: 02/11/2012, 11:08

... introduced for energy management, new devices and generators among others, is to reduce the energy consumption in buildings, they must ensure a proper comfort level and well being of their users [3] ... transferred to the water surface and transformed into evaporation latent heat, the dry bulb air temperature diminishes, while this loose of sensible heat is simultaneously compensated for the vapor absorption, ... of the adiabatic tunnel described before To clarify what has been exposed before, the evolution of an air stream originally at 25ºC and 30% of RH is described for different cases of water temperature...

Ngày tải lên: 05/09/2013, 16:10

... actually small It should therefore be reserved for urban and rural water supply use only, predominantly for rural areas and town that cannot avail of good quality surface water 1.2.2 Problems ... on Water Resources Management to provide information to staff for their monitoring activities will be established The information unit with a server for update and share the monitoring result ... Room for information unit • Qualified staffs • Places to organize seminars, training courses • Man-power to develop and maintain computer network Foreign partner will contribute: • Cost for organizing...

Ngày tải lên: 04/11/2013, 20:15

... ESI Nozzle for Protein Mass Spectrometry SEM of Capillary Tips 16+ 15+ 17+ 2.5 mm 18+ 20+ 14+ Relative Abundance 19+ 21+ 22+ 23+ 13+ 24+ 25+ 600 12+ 800 1000 1200 1400 m/z Taylor Cone Formation ... Data Hand-Fitted Curve -54 -72 -90 Background 60 Hz averaged away -108 time (msec) Traditional ESI for Mass Spectrometry particle filter air flow MS Inlet Vacuum inside MS Glass capillary 1-4 kV ... (V) 0.65 0.6 0.55 0.5 0.45 1000 2000 3000 P ressu re (p si) 4000 5000 MEMS Pressure Sensor Probe for Intraocular Pressure Measurement Wafer with flexible pressure sensor skins Flexible ribbon Pressure...

Ngày tải lên: 22/12/2013, 21:17

... thus well suited for monitoring biological systems for long periods of time, which is important for developing robust sensors for cancer assays and for in vivo imaging A further advantage of QDs ... exchange S i– OH Multicolor quantum dots for molecular diagnostics = Expert Review of Molecular Diagnostics Figure Diagram of two general strategies for phase transfer of tri-n-octylphosphine ... Diagn 6(2), (2006) Multicolor quantum dots for molecular diagnostics immunohistochemistry for protein detection and fluorescence in situ hybridization for nucleic acid detection using QD probes...

Ngày tải lên: 15/02/2014, 05:20

... corpora for parser adaptation Turning briefly to previous results on Medline data, the best comparative study of parsers is that of Clegg and Shepherd (2005), which evaluates several statistical parsers ... parsers were not close However, several very good current parsers were not available when this paper was written (e.g., the Berkeley Parser (Petrov et al., 2006)) However, since the newer parsers ... Evaluating and integrating treebank parsers on a biomedical corpus In Proceedings of the ACL Workshop on Software Matthew Lease and Eugene Charniak 2005 Parsing biomedical literature In Second International...

Ngày tải lên: 20/02/2014, 09:20

... different PPI annotation formats For a comparative evaluation Pyysalo et al (2008) put all of them in a common format which has become the standard evaluation format for the PPI task In our experiments, ... negative cue and walk features formative words which produce uninformative walk features Hence, they are not suitable for walk feature generation MEDT suits better for this purpose The walk features ... contextual information of the words occurring before, between and after the pair of entities (to be investigated for RE) in the corresponding sentence; while the LC kernel exploits contextual information...

Ngày tải lên: 08/03/2014, 21:20

... plasma [14] (50 mW power, 30 sccm flow rate for min) for two purposes One is for cleaning the sample surface, and the other one is for generating a hydrophilic surface The wires are first put into 3-aminopropyltriethoxy ... silane (APTES) solution (3% in ethanol with 5% water) for h The device is rinsed with ethanol solution for five times before baking at 110 ◦ C for 10 After wire bonding, 2% urease in 20 mM NaCl solution ... solution and silicon nanowires 2.2 Surface modification The silicon wire FET sensor is modified with urease following procedure below Before modification, the Al2 O3 surface was treated with oxygen...

Ngày tải lên: 16/03/2014, 15:25