surface charge of scls composed with different

Sulfatides containing liposomes as novel nano carriers targeting gliomas

Sulfatides containing liposomes as novel nano carriers targeting gliomas

... potential (surface charge) of SCLs composed with different content of sulfatides 87 Fig.4.3 Schematic illustrations of active drug loading 88 Fig.4.4 DOX quantifications: standard curve of DOX vs ... Binding of SCLs to the Extracellular Matrix of Glioma Cells 42 2.4.1 The binding of SCLs to the ECM of U-87MG cells does not involved HSPG 42 2.4.2 Rh-PE labeled SCLs colocalized with TN-C in ECM of ... accumulation of SCLs with different size distributions in tumor bearing nude viii 6.2.6.2 The accumulation of SCLs (50 nm) in tumor bearing nude mice a time course study 125 6.2.6.3 The accumulation of SCLs...

Ngày tải lên: 11/09/2015, 16:06

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Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf

... enrichment of AcH4-K16 within transcribed genes is closely correlated with binding of both MOF and Tip60 (equivalent to Esa1 in yeast NuA4) [124,130] However, in human cells depletion of MOF, but ... borders of active genes within polytene chromosome puffs [78] One of the proposed mechanisms of BE function involves the recruitment of chromatin modifying complexes that create islands of active ... mobilization [91] Within the region of nucleosome mobilization upstream of the GM-CSF gene, it can also be seen that a fraction of the nucleosomes end up as fragments of close packed nucleosomes with a...

Ngày tải lên: 14/02/2014, 18:20

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Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx

Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx

... the roles of these DHSs on the transcription of Ig-b gene and on the maintenance of the active chromatin state Results Generation of DT40/Cre cells with a long deletion in one allele of the Ig-b ... the mechanism of B cell-specific transcription of the Ig-b gene, we generated DT40 ⁄ Cre cells with a 16 kb deletion (16 kb Del) in one allele of the Ig-b locus (Fig 1) Introduction of the 16 kb ... correlate with that observed in transient transfection assays Absence of Ig-b mRNA in cells with a deletion in region II (Fig 4A) demonstrated the essential role of this region in the transcription of...

Ngày tải lên: 19/02/2014, 16:20

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Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt

Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt

... number of groups have previously reported that the challenge of mice with a high dose of LPS leads to a transient autoimmunity characterised by the development of a range of autoantibodies of both ... was established following testing of a number of different forms of LPS, and a wide range of doses, for their ability to induce a strong immunological response without causing excessive toxicity ... co-operates with human and mouse DNase I in the breakdown of chromatin within necrotic cells [64] The importance of this interaction in the overall function of DNase I, especially with respect...

Ngày tải lên: 09/08/2014, 07:20

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Digital Communications I: Modulation and Coding Course

Digital Communications I: Modulation and Coding Course

... to detect Rs [symbols/s] without ISI is Rs/2 [Hz] Equivalently, a system with bandwidth W=1/2T=Rs/2 [Hz] can support a maximum transmission rate of 2W=1/T=Rs [symbols/s] without ISI Rs Rs = ≤W ... km/h Lecture 22 Example of eye pattern with ISI: Binary-PAM, SRRQ pulse Non-ideal channel and no noise hc (t ) = δ (t ) + 0.7δ (t − T ) Lecture 23 Example of eye pattern with ISI: Binary-PAM, SRRQ ... Example of eye pattern: Binary-PAM, SRRQ pulse Perfect channel (no noise and no ISI) Lecture 16 Example of eye pattern: Binary-PAM, SRRQ pulse … AWGN (Eb/N0=20 dB) and no ISI Lecture 17 Example of...

Ngày tải lên: 18/10/2013, 06:15

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Quantitative aspects of ruminant digestion and metabolism - Phần 1

Quantitative aspects of ruminant digestion and metabolism - Phần 1

... of 90 to 120 The velocity of propagation of MMC in the jejunum of normally fed sheep is 18 cm/min, which is similar to the value of 20 cm/min for the velocity of digesta flow in the jejunum of ... system of ruminants, leading to studies on the peculiarities of metabolism that cope with the unusual products of microbial digestion The reading list at the end of this chapter gives some of the ... be calculated from the values of the state variables alone, with of course the values of any parameters and constants In this type of mathematical modelling, the differential equations are formed...

Ngày tải lên: 24/10/2013, 17:15

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Quantitative aspects of ruminant digestion and metabolism - Phần 2

Quantitative aspects of ruminant digestion and metabolism - Phần 2

... Proceedings of the Nutrition Society of Australia 14, 153 Faichney, G.J (1990) Effect of level of intake and grinding of lucerne hay on the efficiency of rumination in sheep Proceedings of the Nutrition ... estimates to be made of the partition of digestion, i.e the extent of digestion, absorption and/or secretion occurring in defined segments of the tract Rate of passage is a measure of the time during ... flow of different phases of digesta independently (Faichney, 1980a), does not require that each marker associates exclusively with one phase but does assume uniform distribution of the markers within...

Ngày tải lên: 24/10/2013, 17:15

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If I do … and If I did… & If I knew… I wish I new

If I do … and If I did… & If I knew… I wish I new

... here I wish it didn’t rain so often Ở trời mưa nhiều ớc trời đừng có mưa thường xuyên It’s very crowded here I wish there weren’t so many people (but there are a lot of people) Ở thật đông người ... nói “if somebody would point”) Tôi sợ có chĩa súng vào If I didn’t go to their party, they’d be offended (không nói “If I wouldn’t go”) Nếu không tới dự buổi tiệc họ, họ giận Nhưng nói “if…would” ... go out) Nếu trời tạnh mưa, chơi (= chơi) D Không dùng when câu tương tự câu này: They would be offended if we didn’t accept their invitation (không nói ‘when we didn’t) Họ giận không chấp nhận...

Ngày tải lên: 27/10/2013, 22:15

5 604 2
I will and I am going to do & Will be doing and will have done

I will and I am going to do & Will be doing and will have done

... sánh will be -ing với thể tiếp diễn (continuous) khác: At 10 o’clock yesterday, Sally was in her office She was working (past continuous) Vào lúc 10 ngày hôm qua, Sally văn phòng cô (Lúc đó) cô ... biệt bạn muốn điều hay muốn người khác làm cho bạn điều Ví dụ như: A: Will you be passing the post office when you’re out? Khi bạn bạn ghé ngang qua bưu điện không? B: Probably Why? Có thể Bạn cần...

Ngày tải lên: 27/10/2013, 22:15

5 702 0
Quantitative aspects of ruminant digestion and metabolism - Phần 3

Quantitative aspects of ruminant digestion and metabolism - Phần 3

... of degradation (Dhanoa et al., 1999), providing estimates of the degradation rate of the soluble fraction are available Recovery of matter of non-feed origin in the incubation residue After withdrawal ... underestimation of the extent of degradation The degree of microbial contamination of the residues is variable among different substrates Contamination can have a large impact on the estimates of protein ... Michalet-Doreau, 2000) The exchange of fluids between bag and rumen contents is also determined by open surface area of the bag material (proportion of the total surface area of the bag accounted for by...

Ngày tải lên: 29/10/2013, 00:15

35 432 0
Quantitative aspects of ruminant digestion and metabolism - Phần 4

Quantitative aspects of ruminant digestion and metabolism - Phần 4

... to describe change of large particle content (LP, determined by retention on a screen of aperture 1.18 mm) of the ingested bolus with that of the feed, together with data of Gherardi et al (1992) ... Rate of intake of legumes was higher than for grasses and the extent of size reduction of petioles and stems was correspondingly less (Wilman et al., 1996) The greater ease of breakdown of lucerne ... applicable to the in vivo situation Elucidation of different patterns of fragmentation will require description of the plant tissue of origin and composition of bolus material retained in the mouth prior...

Ngày tải lên: 29/10/2013, 00:15

34 392 0
Woe Is I - Pronouns and Case

Woe Is I - Pronouns and Case

... was Answers whom (object of the preposition from) who (subject of the verb) whom (direct object of the verb) who (subject of the verb) whom (object of the preposition with) who (predicate nominative) ... disapproves of (me, my) leaving the office early Answer: The meaning of the sentence requires the possessive case: my Therefore, the sentence should read: "The boss disapproves of my leaving the office ... and whom is the object of send Question: The taxidermist promised to notify Herman and (7, me) of his plans for the moose Answer: Me (together with Herman) is the object of the infinitive to notify...

Ngày tải lên: 01/11/2013, 16:20

12 268 0
Quantitative aspects of ruminant digestion and metabolism - Phần 5

Quantitative aspects of ruminant digestion and metabolism - Phần 5

... measurements of the rates of production of acetic, propionic and butyric acids in the rumen of sheep on different diets and the correlation between production rates and concentrations of these acids ... the site of binding to the cell wall (i.e pH, availability of metal cofactors, etc.) The surface area of protein accessible to proteases and peptidases may be reduced by the presence of lipids ... composition of supplements), level of intake, retention time of solids and liquids, and the timing of release of energy substrates and nitrogenous materials into the medium (rumen ‘synchrony’) Effect of...

Ngày tải lên: 07/11/2013, 23:15

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Quantitative aspects of ruminant digestion and metabolism - Phần 6

Quantitative aspects of ruminant digestion and metabolism - Phần 6

... digestibility of feed and production of VFA and microbial protein However, the complexity of these analogues, which often employ pulse addition of heterogeneous, particulate substrate and differential ... activates growth of the other species II With different growth-limiting substrates (i) when the different growth-limiting substrates are fed into the culture (ii) when a product of one species ... namely mg of X2 biomass synthesized per mg X1 biomass ingested and mg of X1 biomass per ml of culture Also note that in this set of equations, protozoa not utilize substrate, but obtain all of their...

Ngày tải lên: 07/11/2013, 23:15

22 442 0
Quantitative aspects of ruminant digestion and metabolism - Phần 7

Quantitative aspects of ruminant digestion and metabolism - Phần 7

... (1976) Effect of monensin fed with forage on digestion and the ruminal ecosystem of steers Journal of Animal Science 42, 229–234 Eadie, J.M and Gill, J.C (1971) Effect of the absence of rumen ciliate ... Bacteroides succinogenes Journal of Bacteriology 169, 500–506 Harden, A and Young, W.J (1906) The alcoholic fermentation of yeast juice II The coferment of yeast juice Proceedings of the Royal Society, ... bacterium in the rumen of cattle However, neither of these species could account for ammonia production in vivo P bryantii B1 4, one of the most active strains, had a specific activity of 13.5 nmol/mg...

Ngày tải lên: 07/11/2013, 23:15

34 531 0
Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 8 docx

Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 8 docx

... effect of apparent digestibility of organic matter and an interaction of the latter with level of feed intake Another equation that is often used relates methane production to the intake of three ... average 65% with no starch consumed, to as low as 30% with a consumption of 10 kg of starch per day The effect of soluble carbohydrate on NDF degradation seems to be opposite to that of starch ... highest values of around 80% NDF degradation were all achieved on diets based on fresh ryegrass supplemented with only small quantities of concentrates Consumption of this type of forage with less...

Ngày tải lên: 15/12/2013, 08:15

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Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 9 pptx

Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 9 pptx

... radioactivity of the precursor at the site of metabolic use, causes an underestimation of the rate of conversion of precursor to product Consequently, estimates of the rate of conversion of precursor ... of time, the rate of entry of the metabolite into the pool equals the rate of exit and represents its rate of turnover The turnover rate may also be determined by measuring the rate of exit of ... concern with the use of 13 C to determine oxidation of m is the amount of labelled m required to measurably enrich CO2 For many metabolites with low rates of oxidation, the infusion rate of 13...

Ngày tải lên: 15/12/2013, 08:15

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Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 10 pptx

Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 10 pptx

... Oxidation of NEFA Whole body Two methods are commonly employed to measure the oxidation rate of NEFA Either the entry rate of NEFA and CO2 are determined along with the contribution of NEFA to ... represent flux of NEFA whether in the form of TAG-fatty acids or NEFA The flux of NEFA into adipose tissue represents the sum of TAG synthesis in all tissues The estimated rate of lipogenesis ... development of fatty liver The aetiology of this accumulation seems to be associated with liver uptake of NEFA in proportion to concentration, attainment of maximal rates of ketogenesis and therefore a...

Ngày tải lên: 15/12/2013, 09:15

28 436 0
Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 11 ppt

Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 11 ppt

... representation of the specific activity of the tracer following the administration of a constant infusion (a) or of a flooding-dose (b) of a labelled amino acid In (a) the ratio of the isotopic activity of ... mass of the GIT increases with intake, and the importance of its different compartments varies according to the composition of the diet Protein mass of the ruminant GIT accounts for 4–6% of whole-body ... approaches (e.g measurements of protein levels for some enzymes of the ubiquitination machinery and proteasomal subunits, of the rate of ubiquitination of protein substrates, and of proteasome activities)...

Ngày tải lên: 15/12/2013, 09:15

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Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 12 docx

Tài liệu Quantitative aspects of ruminant digestion and metabolism - Phần 12 docx

... knowledge of the mechanics of protein turnover provides useful information, the factors that determine the rate of protein turnover are of greater interest Characterization of the energetic cost of ... for maintenance of the animal, and that contained within animal products (milk, tissue, fetus) is associated with the production of heat This quantity of heat, produced as a result of ß CAB International ... of the HI as: (i) the work of nutrient metabolism (inefficiencies in the conversion of nutrients to ATP); (ii) the work associated with the digestion and mastication of food; (iii) the heat of...

Ngày tải lên: 15/12/2013, 09:15

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